Rak jelita cienkiego
Objawy

Rak jelita cienkiego jest rzadkim nowotworem złośliwym, który często rozwija się bezobjawowo lub z niespecyficznymi symptomami, co utrudnia wczesne rozpoznanie. Wczesne objawy obejmują ból brzucha o charakterze kurczowym, niewyjaśnioną utratę masy ciała, nudności, wymioty oraz objawy anemii, takie jak osłabienie i zmęczenie. W miarę progresji choroby mogą pojawić się krwawienia z przewodu pokarmowego (widoczne jako krew w stolcu lub smolisty stolec), żółtaczka (szczególnie przy lokalizacji guza w dwunastnicy), wodnista biegunka, uczucie pełności, a także wyczuwalny guz w jamie brzusznej. Zaawansowane stadia mogą prowadzić do powikłań takich jak niedrożność jelita, perforacja czy wgłobienie. Lokalizacja guza wpływa na specyfikę objawów, np. guzy dwunastnicy często powodują żółtaczkę i refluks żołądkowo-przełykowy, natomiast guzy neuroendokrynne mogą wywoływać zespół rakowiaka z objawami takimi jak zaczerwienienie twarzy, biegunka i świszczący oddech.

Objawy Raka Jelita Cienkiego

Rak jelita cienkiego jest rzadkim nowotworem złośliwym, który rozwija się w tkankach jelita cienkiego. W porównaniu do innych nowotworów przewodu pokarmowego, takich jak rak żołądka czy rak jelita grubego, występuje znacznie rzadziej. Nowotwór ten może objawiać się na różne sposoby, a wczesne rozpoznanie ma kluczowe znaczenie dla skuteczności leczenia.12

Wczesne objawy

We wczesnych stadiach rak jelita cienkiego często nie daje żadnych objawów lub powoduje objawy niespecyficzne, co znacznie utrudnia wczesne rozpoznanie. Wiele osób nie doświadcza żadnych symptomów na wczesnym etapie choroby, a objawy mogą być subtelne i nie powodować uczucia choroby.123

Pierwsze objawy raka jelita cienkiego są zwykle niewyraźne i mogą mieć inne, bardziej powszechne przyczyny. Niestety, oznacza to, że często mija co najmniej kilka miesięcy od momentu wystąpienia objawów do czasu zdiagnozowania nowotworu.12

Najczęstszymi wczesnymi objawami raka jelita cienkiego są:12

  • Ból lub skurcze w środkowej części brzucha – często pierwszym objawem jest ból w okolicy żołądka. Ból ten często ma charakter kurczowy i może nie być stały. Na przykład, może zacząć się lub nasilić po jedzeniu.12
  • Niewyjaśniona utrata masy ciała – chudnięcie bez stosowania diety.12
  • Nudności i wymioty.12
  • Osłabienie i uczucie zmęczenia (często wynikające z anemii).12

Postępujące objawy

Wraz z rozwojem nowotworu, objawy mogą się nasilać i pojawiać się nowe symptomy. Gdy guz staje się większy, może spowalniać przechodzenie strawionego pokarmu przez jelito, co prowadzi do zwiększonego bólu.1

Do objawów postępującego raka jelita cienkiego należą:12

  • Krwawienie z przewodu pokarmowego – obecność krwi w stolcu, która może wyglądać na czerwoną lub czarną, smołowatą. Krwawienie może być powolne, prowadząc do anemii, lub gwałtowne, powodując czarny, smolisty stolec i uczucie osłabienia.12
  • Anemia – niska liczba czerwonych krwinek, powodująca osłabienie, zmęczenie i bladą skórę.12
  • Żółtaczka – zażółcenie skóry i białek oczu. Może wystąpić, gdy guz w dwunastnicy (pierwszej części jelita cienkiego) blokuje przewód żółciowy, co uniemożliwia przepływ treści z wątroby do jelita.12
  • Wodnista biegunka lub zmiany w rytmie wypróżnień.12
  • Uczucie pełności lub wzdęcia w brzuchu.1
  • Wyczuwalny guz w jamie brzusznej.12

Poważne powikłania

W zaawansowanych stadiach rak jelita cienkiego może prowadzić do poważnych powikłań, które wymagają natychmiastowego leczenia:12

  • Niedrożność jelita – jeśli guz stanie się wystarczająco duży, może spowodować całkowitą niedrożność, w której jelito jest całkowicie zablokowane i nic nie może się przez nie przedostać. Prowadzi to do silnego bólu z ostrymi nudnościami i wymiotami.12
  • Perforacja jelita – rzadko nowotwór może spowodować powstanie otworu (perforacji) w ścianie jelita. Ten otwór pozwala zawartości jelita wylać się do jamy brzusznej. Objawy perforacji mogą obejmować nagły, silny ból, nudności i wymioty.12
  • Wgłobienie – czasami nowotwory jelita cienkiego mogą powodować wgłobienie (gdy jedna część jelita wsuwa się do przylegającej części).1

Objawy specyficzne dla lokalizacji

Objawy raka jelita cienkiego mogą różnić się w zależności od lokalizacji guza:1

Rak dwunastnicy

Większość nowotworów jelita cienkiego (zwłaszcza gruczolakoraki) rozwija się w dwunastnicy. Nowotwory rozwijające się w dwunastnicy często znajdują się w okolicy brodawki Vatera.12

Specyficzne objawy dla raka dwunastnicy obejmują:12

  • Żółtaczkę – guzy w dwunastnicy mogą czasami rozrastać się na tyle, aby zablokować przewód żółciowy wspólny, wąską rurkę, która przenosi żółć z wątroby do jelita cienkiego, gdzie pomaga w rozkładzie i wchłanianiu pokarmu. Gdy wystąpi ta blokada, żółć cofa się w wątrobie i dostaje się do krwiobiegu. W rezultacie dochodzi do żółtaczki, która prowadzi do takich objawów jak zażółcenie skóry i oczu, ciemny mocz, jasne stolce i swędzenie.1
  • Refluks żołądkowo-przełykowy.1
  • Krew w stolcu.1
  • Zaparcia.1
Guzy neuroendokrynne

Guzy neuroendokrynne jelita cienkiego mogą rozwijać się powoli i mogą nie powodować objawów. Jeśli występują objawy, zależą one od tego, gdzie w organizmie znajduje się guz i czy komórki guza wytwarzają hormony.1

Niektóre bardziej zaawansowane guzy neuroendokrynne wytwarzają nadmiar hormonów (takich jak serotonina), które mogą powodować zespół objawów znany jako zespół rakowiaka. Objawy mogą obejmować:12

  • Zaczerwienienie twarzy – nagłe zaczerwienienie skóry, szczególnie na ramionach i górnej części ciała.12
  • Biegunkę.1
  • Świszczący oddech.1
  • Rzadko, chorobę serca rakowiaka prowadzącą do duszności.1

Progresja Raka Jelita Cienkiego

Rak jelita cienkiego zazwyczaj rozwija się powoli. Eksperci uważają, że rak jelita cienkiego rozwija się podobnie jak rak jelita grubego. Najpierw pojawia się jako mały rozrost na wewnętrznej wyściółce jelita (polip), który z czasem staje się nowotworem.1

Zmiany DNA i rozwój guza

Rak jelita cienkiego pojawia się, gdy komórki rozwijają zmiany w swoim DNA. Zmiany te nakazują komórkom szybkie namnażanie się. Komórki żyją nadal, gdy zdrowe komórki umierałyby w ramach naturalnego cyklu życia. Powoduje to zbyt dużą liczbę komórek, które mogą tworzyć masę zwaną guzem. Komórki mogą naciekać i niszczyć zdrowe tkanki organizmu.1

Stadia zaawansowania

Określenie stadium raka jelita cienkiego opiera się na tym, ile nowotworu znajduje się w organizmie, gdzie został po raz pierwszy zdiagnozowany, czy nowotwór się rozprzestrzenił i dokąd.1

Stadium nowotworu może pomóc zespołowi medycznemu zaplanować leczenie. Może również powiedzieć, jak nowotwór może reagować na leczenie i jakie jest prawdopodobieństwo nawrotu nowotworu.1

Stopniowanie gruczolakoraka jelita cienkiego przebiega następująco:1

  • Stadium 0 – guz nie wykracza poza górną warstwę komórek błony śluzowej w jelicie cienkim.
  • Stadium I – guz wrósł w głębsze komórki, ale nie rozprzestrzenił się do węzłów chłonnych.
  • Stadium II – może być A, B lub C, w zależności od tego, jak głęboko guz wrósł w komórki. Nowotwór nadal nie rozprzestrzenił się do pobliskich węzłów chłonnych.
  • Stadium III – może być również A, B lub C, w zależności od tego, do ilu węzłów chłonnych rozprzestrzenił się nowotwór.
  • Stadium IV – nowotwór rozprzestrzenił się (przerzutował) do odległych części ciała, takich jak jajniki, płuca, otrzewna lub wątroba.

Stopień zróżnicowania

Stopień zróżnicowania nowotworu opisuje, jak bardzo komórki nowotworowe różnią się od normalnych komórek i jak szybko komórki nowotworowe rosną. Patolog określi stopień nowotworu po obejrzeniu komórek pod mikroskopem.1

Rak jelita cienkiego może mieć stopień 1, 2, 3 lub 4. Im niższa liczba, tym niższy stopień zróżnicowania. Stopień zróżnicowania nowotworu może pomóc zespołowi medycznemu zaplanować leczenie.1

Przerzuty

Z czasem komórki nowotworowe mogą oderwać się i rozprzestrzenić do innych części ciała. Zaawansowany rak jelita cienkiego może rozprzestrzeniać się do innych części ciała. Gdy nowotwór się rozprzestrzenia, nazywa się to nowotworem przerzutowym.12

Rak jelita cienkiego najczęściej rozprzestrzenia się do wątroby, ale może też dawać przerzuty do węzłów chłonnych, trzustki, otrzewnej i płuc.123

Nawrót choroby

Rak jelita cienkiego może nawrócić (powrócić) po leczeniu. Nowotwór może wrócić w jelicie cienkim lub w innych częściach ciała.12

Rokowanie

Rokowanie (szansa na wyzdrowienie) i opcje leczenia zależą od następujących czynników:1

  • Rodzaju raka jelita cienkiego.
  • Czy nowotwór jest tylko w wewnętrznej wyściółce jelita cienkiego, czy rozprzestrzenił się do ściany jelita cienkiego lub poza nią.
  • Czy nowotwór rozprzestrzenił się do innych miejsc w organizmie, takich jak węzły chłonne, wątroba lub otrzewna.
  • Czy nowotwór może być całkowicie usunięty chirurgicznie.
  • Czy nowotwór jest nowo zdiagnozowany, czy wystąpił nawrót.

Wskaźnik przeżywalności różni się w zależności od typu raka jelita cienkiego, stadium i miejsca, w którym guz rozpoczął się w jelicie cienkim. Na przykład, 65% osób zdiagnozowanych z gruczolakorakiem we wczesnym stadium żyje pięć lat później. Wskaźnik przeżywalności w późniejszych stadiach jest znacznie niższy i wynosi 4%. Guzy rakowiakowate we wczesnym stadium mają pięcioletni wskaźnik przeżywalności 95%, podczas gdy nowotwory w późniejszym stadium mają wskaźnik przeżywalności 42%.12

Ogólnie rzecz biorąc, rokowanie dla nowotworów jest lepsze, gdy zostanie on wykryty we wczesnych stadiach. Leczenie może być trudniejsze, jeśli rak jelita cienkiego zostanie znaleziony w późniejszych stadiach.12

Wyzwania w diagnozie

Raki jelita cienkiego są trudne do zdiagnozowania. Jelito cienkie to część ciała, która nie jest regularnie badana, w przeciwieństwie do okrężnicy, w przypadku której pacjenci poddawani są regularnym badaniom przesiewowym kolonoskopii. A osoby z rakiem jelita cienkiego często nie zauważają objawów, dopóki ich choroba nie postąpi.1

Ze względu na opóźnienie w diagnozie, które występuje w przypadku rozpoznania raka jelita cienkiego, pacjenci często zgłaszają się z powikłaniami w późniejszym stadium choroby do pierwszej oceny. Najczęściej odnotowywane powikłania to krwawienia z górnego i dolnego odcinka przewodu pokarmowego, niedrożność jelita cienkiego, perforacja jelita cienkiego i wtórne zapalenie otrzewnej.1

Rak jelita cienkiego może rozwijać się bez objawów. Dlatego ważne jest, aby brać udział w badaniach przesiewowych i nie ignorować żadnych utrzymujących się dolegliwości jelitowych.12

Kolejne rozdziały

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Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 09.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 Small Intestine Cancer: Symptoms, Causes, Prognosis & Treatment
    https://my.clevelandclinic.org/health/diseases/6225-small-intestine-cancer
    The symptoms of small intestine cancer vary depending on the type of tumor and where its located. Sometimes, tumors are asymptomatic, which means they dont cause symptoms. For example, carcinoid tumors often dont cause symptoms. They may only be found incidentally during an imaging procedure for an unrelated issue. […] Symptoms may include: Abdominal pain or cramps. A lump in your abdomen. Nausea, vomiting and diarrhea. Unexplained weight loss. Anemia. Jaundice (yellowing of your eyes or skin). Bloody stool (may appear red or black in the toilet). Flushed skin, especially purplish coloring on your arms and upper body. […] Cancer staging can provide information on the size of a tumor, where its located and whether its spread (metastasized). Tests and procedures to stage small intestine cancer usually happen during diagnosis.
  • #1 Small Intestine Adenocarcinoma > Fact Sheets > Yale Medicine
    https://www.yalemedicine.org/conditions/small-intestine-adenocarcinoma
    Symptoms include abdominal pain, unexplained weight loss, blood in the stools, indigestion […] Many people dont have symptoms during the early stages of disease. Those who do may experience: abdominal pain or cramping, unexplained weight loss, bleeding in the gastrointestinal tract, leading to blood in bowel movements (which may appear as fresh blood or dark-colored stool), indigestion, bloating, nausea and/or vomiting, diarrhea, a change in bowel habits, small bowel obstruction, loss of appetite, weakness, jaundice, anemia, trouble breathing. […] Small intestine cancers are difficult to diagnose. The small intestine is a body part that isnt screened regularly, unlike the colon for which patients undergo regular screening colonoscopies. And people with small intestine cancer often dont notice symptoms until their disease has progressed. […] The earlier that small intestine cancer is diagnosed and treated, the better the outlook is for patients.
  • #1 Signs and Symptoms of Small Intestine Cancer (Adenocarcinoma) | American Cancer Society
    https://www.cancer.org/cancer/types/small-intestine-cancer/detection-diagnosis-staging/signs-symptoms.html
    The symptoms of small intestine cancers are often vague and can have other, more common causes. Unfortunately, this means that its often at least several months from the time symptoms start until the cancer is diagnosed. […] Some of the more common symptoms of small intestine cancer are: Pain in the belly (abdomen), Nausea and vomiting, Weight loss (without trying), Weakness and feeling tired (fatigue), Dark-colored stools (from bleeding into the intestine), Low red blood cell counts (anemia), Yellowing of the skin and eyes (jaundice). […] Often, the first symptom is pain in the stomach area. This pain is often crampy and may not be constant. For example, it may start or get worse after you eat. […] As the tumor gets larger, it can slow the passage of digested food through the intestine. This can lead to increased pain. If the tumor gets large enough, it can cause an obstruction, in which the intestine is completely blocked and nothing can move through. This leads to pain with severe nausea and vomiting.
  • #1 Small bowel cancer – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/small-bowel-cancer/symptoms-causes/syc-20352497
    Symptoms of small bowel cancer include: […] Abdominal pain. […] Yellowing of the skin and the whites of the eyes, called jaundice. […] Feeling very weak or tired. […] Nausea. […] Vomiting. […] Losing weight without trying. […] Blood in the stool, which might look red or black. […] Watery diarrhea. […] Skin flushing. […] Small bowel cancer happens when cells develop changes in their DNA. […] The changes tell the cells to multiply quickly. […] The cells continue living when healthy cells would die as part of their natural life cycle. […] This causes too many cells. […] The cells might form a mass called a tumor. […] The cells can invade and destroy healthy body tissue. […] In time, the cells can break away and spread to other parts of the body. […] Advanced small bowel cancer can spread to other parts of the body. […] When cancer spreads, it’s called metastatic cancer. […] Small bowel cancer most often spreads to the liver.
  • #1 Small Intestine Cancer: Symptoms, Types, and Treatment
    https://www.healthline.com/health/small-intestine-cancer
    In its earlier stages, small intestine cancer can be associated with abdominal pain and discomfort. This may be because food cant pass efficiently through your digestive tract. […] Other symptoms you may experience if diagnosed with small intestine cancer include: nausea, abdominal cramps, bloating, appetite loss. […] If your cancer has progressed, more severe symptoms from small intestine cancer may include: fatigue, weight loss, weakness, vomiting, vitamin deficiency, anemia, diarrhea, bloody or black stools, lump in the abdomen, jaundice. […] If you experience any of these symptoms or if they worsen over time, seek immediate medical attention. Symptoms from this form of cancer can also be an indication of other gastrointestinal diseases. Early detection can help ensure you receive the best treatment for your condition.
  • #1 Signs and Symptoms of Small Intestine Cancer (Adenocarcinoma) | American Cancer Society
    https://www.cancer.org/cancer/types/small-intestine-cancer/detection-diagnosis-staging/signs-symptoms.html
    Rarely, a cancer will cause a hole (perforation) to form in the wall of the intestine. This hole lets the contents of the intestine spill into the abdomen. Symptoms of perforation can include sudden severe pain, nausea, and vomiting. […] Sometimes a tumor will start bleeding into the intestine. If the bleeding is slow, it could lead to a low red blood cell count (anemia) over time. Symptoms of anemia include weakness and fatigue. If the bleeding is rapid, the stool can become black and tarry from digested blood, and the person may feel lightheaded or even pass out. […] Less often, a tumor in the duodenum (the first part of the small intestine) can cause jaundice. This can happen if the tumor blocks the bile duct, which can prevent the contents from the liver from entering the intestine.
  • #1
  • #1 Bowel cancer
    https://www.cancervic.org.au/cancer-information/types-of-cancer/bowel_cancer/bowel-cancer.html
    Some people have no symptoms and the cancer is found through screening. However, many people with bowel cancer experience some of the symptoms listed below. […] Talk to your doctor if you have any of these symptoms, especially if they are ongoing, get worse, or if there is any bleeding: blood in or on faeces (poo) or on the toilet paper; this might be bright red or make the poo look dark brown or black, a persistent or unexplained change in bowel habits, such as diarrhoea or loose stools, constipation or smaller, more frequent bowel movements, a change in the look of faeces (e.g. narrower or with mucus), a feeling of fullness or bloating in the abdomen (belly) or a strange sensation in the rectum, often during a bowel movement, feeling that the bowel hasn’t emptied completely after you have done a poo, losing weight without trying to, rectal or anal pain, a lump in the rectum or anus, abdominal pain or swelling, weakness or fatigue, dizziness or breathlessness, a low red blood cell count (anaemia or iron deficiency), a blockage in the bowel. […] If untreated, bowel cancer can grow into the deeper layers of the bowel wall. It can also spread to the lymph nodes. If the cancer advances further, it can spread to other organs, such as the liver or the lungs.
  • #1 Small Intestine Cancer : Symptoms, Signs and Causes | HCG
    https://www.hcgoncology.com/types-of-cancers/small-intestine-cancer-symptoms-and-causes/
    The presence of a palpable lump in the abdomen can be indicative of an advanced stage of small intestine cancer. This may be accompanied by a feeling of fullness or bloating. […] Small intestine cancer can disrupt normal digestive processes, leading to symptoms like nausea, diarrhea, or vomiting. Persistent gastrointestinal issues could be one of the small intestine cancer signs. […] Chronic bleeding from the cancerous growth may result in anemia, characterized by fatigue, weakness, and pale skin. Monitoring for signs of anemia is crucial for timely detection. […] Unexplained weight loss may be one of the most important small intestine cancer symptoms. The metabolic impact of the cancer can lead to unintended and rapid weight loss. […] Blood in the stool, which may appear as dark, tarry stools or visible red blood, can be one of the small intestine cancer signs. It signals the potential involvement of the gastrointestinal tract, necessitating prompt investigation.
  • #1 Small Bowel Cancer – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK560725/
    The evaluation and diagnostic process of small bowel cancer consist of laboratory, imaging, and endoscopic evaluations. Unfortunately, the diagnosis is often delayed due to the nonspecific nature of presenting symptoms and low suspicion in evaluating generalized abdominal pain for small bowel cancer. […] Due to the delay in diagnosis that occurs with a small bowel cancer diagnosis, patients often present with complications later in the disease for their initial evaluation. The most common complications noted include upper and lower gastrointestinal bleeding, small bowel obstruction, small bowel perforation, and subsequent peritonitis.
  • #1 Small-Intestine Cancer – Digestive Disorders – Merck Manual Consumer Version
    https://www.merckmanuals.com/home/digestive-disorders/tumors-of-the-digestive-system/small-intestine-cancer
    Blood in the stool is a common symptom, but sometimes the cancer blocks the intestine, causing crampy abdominal pain and vomiting. […] Adenocarcinoma may cause bleeding into the intestine, which shows up as blood in the stool, and obstruction, which in turn may lead to crampy abdominal pain, expansion (distention) of the abdomen, and vomiting. […] Sometimes cancers of the small intestine cause intussusception (when one part of the intestine telescopes into an adjacent part).
  • #1 Small intestine cancer – Wikipedia
    https://en.wikipedia.org/wiki/Small_intestine_cancer
    Small intestine cancer is a cancer of the small intestine. It is relatively rare compared to other gastrointestinal malignancies such as gastric cancer (stomach cancer) and colorectal cancer. Symptoms include vomiting blood, blood in the stool. Experts believe that small intestine cancer develops much like colorectal cancer. It first begins as a small growth on the inner lining of the intestine (polyp), which over time becomes cancer. Most small intestine cancers (especially adenocarcinomas) develop in the duodenum. Cancers developed in the duodenum are often found at the ampulla of Vater.
  • #1 Duodenal Cancer: Types, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22735-duodenal-cancer
    In its early stages, duodenal cancer often causes no symptoms. As the tumor grows, it may block proper digestion. You may have symptoms such as nausea, abdominal pain or constipation. […] In early stages, you may have no symptoms of duodenal cancer. If the intestinal tumor grows, you may have symptoms that affect your digestive system, such as nausea, constipation or abdominal cramps. […] Often, you dont have any symptoms of duodenal cancer when the tumor is small. As the tumor grows, you may have: Abdominal pain. Acid reflux. Blood in your stool. Constipation. Nausea or vomiting. Unexplained weight loss. […] In general, the outlook for cancer is better when you detect it in early stages. It can be harder to treat if you find duodenal cancer in later stages. […] Duodenal cancer is cancer in the first portion of your small intestine. It may interfere with digestion and nutrient absorption. In early stages, you often have no symptoms of duodenal cancer. As cancer progresses, you may have constipation, abdominal pain, nausea or vomiting.
  • #1 Diagnosing Small Intestine Cancer | NYU Langone Health
    https://nyulangone.org/conditions/small-intestine-cancer/diagnosis
    Symptoms of small intestine cancer include abdominal pain, weight loss, nausea, vomiting, and gastrointestinal bleeding. […] Tumors in the duodenum can sometimes grow large enough to block the common bile duct, a narrow tube that carries bile from the liver to the small intestine, where it aids in the breakdown and absorption of food. When this blockage occurs, bile backs up in the liver and enters the bloodstream. Eventually, this results in jaundice, which leads to symptoms such as yellowing of the skin and eyes, dark urine, light-colored stools, and itching.
  • #1
    https://www.cancervic.org.au/cancer-information/types-of-cancer/small_bowel_cancer/small_bowel_overview.html
    Small bowel cancer can be difficult to diagnose, and symptoms may be vague and caused by other conditions. Symptoms may include: abdominal (tummy) pain […] unexplained weight loss […] a lump in the abdomen […] blood in the stools or on the toilet paper […] changes in bowel habits, including diarrhoea or constipation […] feeling sick (nausea) or vomiting […] tiredness and weakness, caused by a low red blood cell count (anaemia) […] yellowing of the skin and eyes (jaundice). […] Small bowel neuroendocrine tumours can develop slowly and may not cause symptoms. If you do have symptoms it will depend on where in the body the tumour is and whether the tumour cells are producing hormones. […] Some neuroendocrine tumours that are more advanced produce excess hormones (such as serotonin) that can cause a group of symptoms known as carcinoid syndrome. Symptoms may include facial flushing, diarrhoea, wheezing and, rarely, carcinoid heart disease leading to shortness of breath.
  • #1
    http://www.bccancer.bc.ca/health-info/types-of-cancer/digestive-system/small-bowel
    What are the signs and symptoms of small bowel cancer? Pain or cramps in your abdomen (area below your ribs and above your pelvis). This is a common symptom. […] Having one or more of these symptoms does not mean you have small bowel cancer. These symptoms can also happen because of other problems. For this reason, a person may not be diagnosed with small bowel cancer until the cancer is more advanced. […] What are the stages of small bowel cancer? Staging describes the cancer. Staging is based on how much cancer is in the body, where it was first diagnosed, if the cancer has spread and where it has spread to. […] The stage of the cancer can help your health care team plan your treatment. It can also tell them how your cancer might respond to treatment and the chance that your cancer may come back (recur).
  • #1 Small Intestine Cancer | UPMC Hillman Cancer Center
    https://hillman.upmc.com/cancer-care/colorectal-gi/types/small-intestine
    Small intestine cancers are rare. […] Some early warning signs of small intestine cancer include: Anemia. Blood in the stool. Diarrhea. Lump in the stomach. Pain or swelling in the middle of the stomach. Unexplained weight loss. Weakness and fatigue. […] In the early stages, symptoms may be vague and hard to connect to cancer. Other digestive problems can cause like symptoms. […] Doctors stage the progress of small intestine adenocarcinoma as follows: Stage 0 the tumor hasn’t gone beyond the top layer of mucosa cells in the small intestine. […] Stage I the tumor has grown into deeper cells but hasn’t spread to lymph nodes. […] Stage II this stage can be A, B, or C. It depends on how deeply the tumor has grown into the cells. The cancer still hasn’t spread to nearby lymph nodes. […] Stage III this stage can also be A, B, or C, depending on how many lymph nodes the cancer has spread to. […] Stage IV the cancer has spread (metastasized) to distant parts of the body, such as ovary, lung, peritoneum, or liver.
  • #1
    http://www.bccancer.bc.ca/health-info/types-of-cancer/digestive-system/small-bowel
    The grade of the cancer describes how different the cancer cells look from normal cells and how fast the cancer cells are growing. A pathologist will give the cancer a grade after looking at the cells under a microscope. […] Small bowel cancer can be grade 1, 2, 3 or 4. The lower the number, the lower the grade. […] The grade of the cancer can help your health care team plan your treatment.
  • #1 Small Intestine Cancer Treatment – NCI
    https://www.cancer.gov/types/small-intestine/patient/small-intestine-treatment-pdq
    Small intestine cancer is a rare disease in which malignant (cancer) cells form in the tissues of the small intestine. […] Signs and symptoms of small intestine cancer include unexplained weight loss and abdominal pain. […] Pain or cramps in the middle of the abdomen. […] Weight loss with no known reason. […] A lump in the abdomen. […] Blood in the stool. […] Small intestine cancer can recur (come back) after it has been treated. […] The cancer may come back in the small intestine or in other parts of the body.
  • #1 caret_down icon
    https://www.spectrumhealth.org/services/cancer/upper-gi-cancers/duodenal-cancer
    Small intestine cancer often starts in the duodenum. […] Signs and symptoms of small intestine cancer include unexplained weight loss and abdominal pain. […] These and other signs and symptoms may be caused by small intestine cancer or by other conditions. Check with your doctor if you have any of the following: Pain or cramps in the middle of the abdomen. Weight loss with no known reason. A lump in the abdomen. Blood in the stool. […] The prognosis (chance of recovery) and treatment options depend on the following: The type of small intestine cancer. Whether the cancer is in the inner lining of the small intestine only or has spread into or beyond the wall of the small intestine. Whether the cancer has spread to other places in the body, such as the lymph nodes, liver, or peritoneum (tissue that lines the wall of the abdomen and covers most of the organs in the abdomen). Whether the cancer can be completely removed by surgery. Whether the cancer is newly diagnosed or has recurred.
  • #1 Small Intestine Cancer: Symptoms, Causes, Prognosis & Treatment
    https://my.clevelandclinic.org/health/diseases/6225-small-intestine-cancer
    The survival rate varies depending on the type of small intestine cancer, the stage and where the tumor started in your small intestine. For instance, 65% of people diagnosed with early-stage adenocarcinomas are alive five years later. The survival rate in later stages is much less at 4%. Early-stage carcinoid tumors have a five-year survival rate of 95%, while later-stage cancers have a survival rate of 42%.
  • #1 Bowel cancer | Better Health Channel
    https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/bowel-cancer
    Bowel cancer can develop with no symptoms. So, it is important to participate in screening. […] In its early stages, bowel cancer may have no symptoms, but if detected early, it can be successfully treated. […] Symptoms may include: Blood in your poo or on the toilet paper, A change in your bowel habits, such as diarrhoea, constipation or smaller more frequent bowel movements, Feeling like you need to poo more often or the feeling of incomplete emptying, Feeling full or bloated in your belly or a strange sensation in the rectum, often during a bowel movement, A change in the appearance of your poo (such as thin stools), Losing weight for no obvious reason, Weakness or fatigue, Anal or rectal pain, A lump in the anus or rectum, A low red blood cell count (anaemia or iron deficiency), which can cause tiredness or weakness, Abdominal (stomach) pain or swelling, A blockage in the bowel. […] Having these symptoms does not mean that you have bowel cancer. People experiencing these symptoms should speak to their doctor.
  • #2 Small intestine cancer – Wikipedia
    https://en.wikipedia.org/wiki/Small_intestine_cancer
    Small intestine cancer is a cancer of the small intestine. It is relatively rare compared to other gastrointestinal malignancies such as gastric cancer (stomach cancer) and colorectal cancer. Symptoms include vomiting blood, blood in the stool. Experts believe that small intestine cancer develops much like colorectal cancer. It first begins as a small growth on the inner lining of the intestine (polyp), which over time becomes cancer. Most small intestine cancers (especially adenocarcinomas) develop in the duodenum. Cancers developed in the duodenum are often found at the ampulla of Vater.
  • #2 Bowel cancer | NHS inform
    https://www.nhsinform.scot/illnesses-and-conditions/cancer/cancer-types-in-adults/bowel-cancer/
    Cancer can sometimes start in the small bowel (small intestine), but small bowel cancer is much rarer than large bowel cancer. […] The symptoms of bowel cancer can be subtle and don’t necessarily make you feel ill. […] Most patients with bowel cancer present with one of the following symptom combinations: a persistent change in bowel habit, causing them to go to the toilet more often and pass looser poo, usually together with blood on or in their poo; a persistent change in bowel habit without blood in their poo, but with abdominal pain; blood in your poo without other haemorrhoid symptoms, like soreness, discomfort, pain, itching, or a lump hanging down outside the back passage; abdominal pain, discomfort or bloating always provoked by eating, sometimes resulting in a reduction in the amount of food eaten and weight loss.
  • #2 Small Intestine Cancer – Gastrointestinal Cancer | UCLA Health Jonsson Comprehensive Cancer Center
    https://www.uclahealth.org/cancer/cancer-services/gi-cancer/conditions/small-intestine-cancer
    The first symptoms of small intestine cancer are usually vague. The most common symptom is pain, sometimes with nausea or vomiting. Symptoms are usually worse after eating. Other symptoms include: […] Losing weight unintentionally […] Dark stools from internal bleeding […] Anemia (low red blood cell count) […] Jaundice (a yellow tint to the skin and eyes).
  • #2 Small bowel cancer – Symptoms and causes – Mayo Clinic
    https://www.mayoclinic.org/diseases-conditions/small-bowel-cancer/symptoms-causes/syc-20352497
    Symptoms of small bowel cancer include: […] Abdominal pain. […] Yellowing of the skin and the whites of the eyes, called jaundice. […] Feeling very weak or tired. […] Nausea. […] Vomiting. […] Losing weight without trying. […] Blood in the stool, which might look red or black. […] Watery diarrhea. […] Skin flushing. […] Small bowel cancer happens when cells develop changes in their DNA. […] The changes tell the cells to multiply quickly. […] The cells continue living when healthy cells would die as part of their natural life cycle. […] This causes too many cells. […] The cells might form a mass called a tumor. […] The cells can invade and destroy healthy body tissue. […] In time, the cells can break away and spread to other parts of the body. […] Advanced small bowel cancer can spread to other parts of the body. […] When cancer spreads, it’s called metastatic cancer. […] Small bowel cancer most often spreads to the liver.
  • #2 Small Intestine Cancer: Understanding the Signs & Symptoms of Tumors in the Small Intestines – Cleveland OH | University Hospitals
    https://www.uhhospitals.org/services/cancer-services/gastrointestinal-cancer/small-intestine-cancer-treatment/about-small-intestine-cancer
    Signs and symptoms of small intestine cancer include unexplained weight loss and abdominal pain. […] These and other signs and symptoms may be caused by small intestine cancer or by other conditions. Check with your doctor if you have any of the following: Pain or cramps in the middle of the abdomen. Weight loss with no known reason. A lump in the abdomen. Blood in the stool. […] The cancer may come back in the small intestine or in other parts of the body.
  • #2 Cancer of the small bowel symptoms | Macmillan Cancer Support
    https://www.macmillan.org.uk/cancer-information-and-support/bowel-cancer/signs-and-symptoms-of-small-bowel-cancer
    The main symptoms of small bowel cancer include cramping pain in the tummy, weight loss for no obvious reason, and feeling sick. […] The main symptoms of small bowel cancer (also called small intestine cancer) include: cramping pain in the tummy (abdominal pain), weight loss for no obvious reason, feeling sick (nausea) and being sick (vomiting), dark or black poo (stools) caused by bleeding from the tumour, tiredness caused by a low number of red blood cells (anaemia) due to blood loss, diarrhoea. […] These symptoms can be caused by conditions other than small bowel cancer. But you should always ask your GP to check any symptoms you are worried about. […] Sometimes the cancer can cause a blockage (obstruction) in the bowel. This may be a complete or partial blockage. […] Rarely, a blockage in the small bowel can cause the bowel to tear. This is a serious condition that usually happens suddenly. It needs to be treated with surgery.
  • #2 Signs and Symptoms of Small Intestine Cancer (Adenocarcinoma) | American Cancer Society
    https://www.cancer.org/cancer/types/small-intestine-cancer/detection-diagnosis-staging/signs-symptoms.html
    The symptoms of small intestine cancers are often vague and can have other, more common causes. Unfortunately, this means that its often at least several months from the time symptoms start until the cancer is diagnosed. […] Some of the more common symptoms of small intestine cancer are: Pain in the belly (abdomen), Nausea and vomiting, Weight loss (without trying), Weakness and feeling tired (fatigue), Dark-colored stools (from bleeding into the intestine), Low red blood cell counts (anemia), Yellowing of the skin and eyes (jaundice). […] Often, the first symptom is pain in the stomach area. This pain is often crampy and may not be constant. For example, it may start or get worse after you eat. […] As the tumor gets larger, it can slow the passage of digested food through the intestine. This can lead to increased pain. If the tumor gets large enough, it can cause an obstruction, in which the intestine is completely blocked and nothing can move through. This leads to pain with severe nausea and vomiting.
  • #2 Small Bowel Cancer – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK560725/
    Small bowel cancer encompasses a series of malignant lesions that may be identified throughout the small intestine (SI). […] The majority of these lesions cause multiple nonspecific symptoms, which often leads to delay in diagnosis and therefore delay in early intervention with available treatment strategies. Common clinical features include abdominal pain, anorexia, gastrointestinal bleeding, and weight loss. More advanced processes can present with perforation, small bowel obstruction, or obstructive jaundice. […] Most small bowel cancers have similar clinical presentations except for neuroendocrine tumors, which can present with symptoms specific to the products secreted from the neurosecretory granules contained within the malignant cells. Nonspecific mid abdominal pain, unexplained weight loss, and gastrointestinal bleeding are three of the most common clinical symptoms. The abdominal pain is generally described as intermittent and crampy, with a small percentage of cases associated with nausea and vomiting. Larger neoplastic lesions can present with more severe conditions such as acute small bowel obstruction or perforation, with obstruction presenting more commonly than perforation.
  • #2 Small Intestine Cancer: Symptoms, Causes, Prognosis & Treatment
    https://my.clevelandclinic.org/health/diseases/6225-small-intestine-cancer
    The symptoms of small intestine cancer vary depending on the type of tumor and where its located. Sometimes, tumors are asymptomatic, which means they dont cause symptoms. For example, carcinoid tumors often dont cause symptoms. They may only be found incidentally during an imaging procedure for an unrelated issue. […] Symptoms may include: Abdominal pain or cramps. A lump in your abdomen. Nausea, vomiting and diarrhea. Unexplained weight loss. Anemia. Jaundice (yellowing of your eyes or skin). Bloody stool (may appear red or black in the toilet). Flushed skin, especially purplish coloring on your arms and upper body. […] Cancer staging can provide information on the size of a tumor, where its located and whether its spread (metastasized). Tests and procedures to stage small intestine cancer usually happen during diagnosis.
  • #2 Small Intestine Cancer : Symptoms, Signs and Causes | HCG
    https://www.hcgoncology.com/types-of-cancers/small-intestine-cancer-symptoms-and-causes/
    The presence of a palpable lump in the abdomen can be indicative of an advanced stage of small intestine cancer. This may be accompanied by a feeling of fullness or bloating. […] Small intestine cancer can disrupt normal digestive processes, leading to symptoms like nausea, diarrhea, or vomiting. Persistent gastrointestinal issues could be one of the small intestine cancer signs. […] Chronic bleeding from the cancerous growth may result in anemia, characterized by fatigue, weakness, and pale skin. Monitoring for signs of anemia is crucial for timely detection. […] Unexplained weight loss may be one of the most important small intestine cancer symptoms. The metabolic impact of the cancer can lead to unintended and rapid weight loss. […] Blood in the stool, which may appear as dark, tarry stools or visible red blood, can be one of the small intestine cancer signs. It signals the potential involvement of the gastrointestinal tract, necessitating prompt investigation.
  • #2 Diagnosing Small Intestine Cancer | NYU Langone Health
    https://nyulangone.org/conditions/small-intestine-cancer/diagnosis
    Symptoms of small intestine cancer include abdominal pain, weight loss, nausea, vomiting, and gastrointestinal bleeding. […] Tumors in the duodenum can sometimes grow large enough to block the common bile duct, a narrow tube that carries bile from the liver to the small intestine, where it aids in the breakdown and absorption of food. When this blockage occurs, bile backs up in the liver and enters the bloodstream. Eventually, this results in jaundice, which leads to symptoms such as yellowing of the skin and eyes, dark urine, light-colored stools, and itching.
  • #2 Symptoms and getting diagnosed | Bowel cancer | Cancer Research UK
    https://www.cancerresearchuk.org/about-cancer/small-bowel-cancer/symptoms-diagnosing
    Small bowel cancer symptoms include: pain or lump in your tummy (abdomen) […] weight loss […] feeling and being sick […] diarrhoea […] tiredness […] dark black poo, due to bleeding in the small bowel […] blockage in the bowel […] a low number of red blood cells (anaemia) due to bleeding. The symptoms of small bowel cancer can be vague. They can also be symptoms of other conditions, such as irritable bowel disease or inflammatory bowel disease but its important to see your doctor. It can be difficult to diagnose small bowel cancer as the small bowel is in the middle part of the digestive tract, so it can be hard for your doctor to examine. Taking pictures, for example a CT scan of the small bowel can be difficult. Your doctor will arrange for you to have some tests, if you have symptoms that suggest small bowel cancer. The tests will help the doctor see any lump or growth in the bowel. Often doctors wont be able to make a diagnosis until you have surgery to remove a lump. A CT scan can show where the cancer is and whether there are signs that the cancer has spread to anywhere else in the body.
  • #2 Symptoms of small intestine cancer | Canadian Cancer Society
    https://cancer.ca/en/cancer-information/cancer-types/small-intestine/signs-and-symptoms
    Small intestine cancer is very rare. As a result, doctors often look for other causes of symptoms before they check for cancer in the small intestine. This cancer may not cause any signs or symptoms in its early stages. Symptoms often appear if the tumour grows into surrounding tissues and organs or if it blocks the small intestine. Other health conditions can cause the same symptoms as small intestine cancer. […] See your doctor if you have these symptoms. […] pain in the abdomen (in some cases, pain comes on suddenly and is severe) […] nausea […] vomiting […] weight loss […] constipation […] diarrhea […] bleeding from the bowel […] blood in the stool, or black, tarry stool […] fatigue and weakness, which may be caused by anemia. […] In some cases, tumours in the small intestine can cause serious problems. These cancer-related emergencies need to be treated right away: […] a blockage in the intestine (called a bowel obstruction) […] a hole in the intestine (called a bowel perforation).
  • #2 Duodenal Cancer: Types, Symptoms & Treatment
    https://my.clevelandclinic.org/health/diseases/22735-duodenal-cancer
    In its early stages, duodenal cancer often causes no symptoms. As the tumor grows, it may block proper digestion. You may have symptoms such as nausea, abdominal pain or constipation. […] In early stages, you may have no symptoms of duodenal cancer. If the intestinal tumor grows, you may have symptoms that affect your digestive system, such as nausea, constipation or abdominal cramps. […] Often, you dont have any symptoms of duodenal cancer when the tumor is small. As the tumor grows, you may have: Abdominal pain. Acid reflux. Blood in your stool. Constipation. Nausea or vomiting. Unexplained weight loss. […] In general, the outlook for cancer is better when you detect it in early stages. It can be harder to treat if you find duodenal cancer in later stages. […] Duodenal cancer is cancer in the first portion of your small intestine. It may interfere with digestion and nutrient absorption. In early stages, you often have no symptoms of duodenal cancer. As cancer progresses, you may have constipation, abdominal pain, nausea or vomiting.
  • #2 Small Intestine Cancer : Symptoms, Signs and Causes | HCG
    https://www.hcgoncology.com/types-of-cancers/small-intestine-cancer-symptoms-and-causes/
    In cases where small intestine cancer obstructs the bile ducts or affects the liver, jaundice may occur. This manifests as yellowing of the skin and eyes, indicating liver dysfunction. […] Flushing of the skin is one of the small intestine tumor symptoms that is caused by carcinoid tumors. This symptom is often associated with a feeling of warmth and redness. […] Individuals should consider consulting an oncologist under the following circumstances: Presence of persistent abdominal pain or discomfort, Unexplained weight loss, Gastrointestinal symptoms such as nausea, vomiting, or changes in bowel habits, Detection of blood in stool or signs of anemia. […] Small intestine cancer symptoms can include abdominal pain, changes in bowel habits, unexplained weight loss, and gastrointestinal discomfort. Also, in many cases, patients may not experience any early signs of small intestine cancer. Therefore, it is even more important not to ignore any non-specific symptoms and seek medical attention whenever necessary.
  • #2 Small Intestine Cancer Treatment – NCI
    https://www.cancer.gov/types/small-intestine/patient/small-intestine-treatment-pdq
    Small intestine cancer is a rare disease in which malignant (cancer) cells form in the tissues of the small intestine. […] Signs and symptoms of small intestine cancer include unexplained weight loss and abdominal pain. […] Pain or cramps in the middle of the abdomen. […] Weight loss with no known reason. […] A lump in the abdomen. […] Blood in the stool. […] Small intestine cancer can recur (come back) after it has been treated. […] The cancer may come back in the small intestine or in other parts of the body.
  • #2 Small intestine cancer | Canadian Cancer Society
    https://cancer.ca/en/cancer-information/cancer-types/small-intestine
    Symptoms of small intestine cancer include pain in the abdomen, nausea and vomiting. […] Small intestine cancer may spread to the lymph nodes, liver and pancreas. […] Grading small intestine cancer helps predict how fast the cancer is growing.
  • #2 Small Bowel Cancer – GI Cancer
    https://gicancer.org.au/cancer/small-bowel-cancer/
    Small bowel cancer (also known as small intestine cancer) is a rare cancer that occurs when malignant cancer cells grow in the tissue of the small intestine. […] Early stages of small bowel cancer can often present with no symptoms or non-specific symptoms, which can also be commonly found in other illnesses. Most small bowel cancers are diagnosed late at more advanced stages of the disease. Small bowel adenocarcinoma symptoms may include: Blood in stool or on the toilet paper, Unexplained weight loss, A lump in the abdomen, Pain, cramps or swelling in the middle of the abdomen, Anaemia (low red blood cell count), Nausea and vomiting. […] The five-year survival rate after diagnosis for small bowel cancer is 69.1%.
  • #2 Bowel (Colon) Cancer | Causes, Symptoms, Effects & Treatment | Guts UK
    https://gutscharity.org.uk/advice-and-information/conditions/bowel-cancer/
    The development of a bowel cancer from a polyp may take between five and ten years, early on there may be no symptoms at all. The most common symptoms are: […] A bowel cancer can enlarge causing partial or complete blockage of the bowel leading to abdominal pain, constipation and bloating. Sometimes tiny amounts of bleeding may go unnoticed but result in the development of anaemia, a low blood count. Anaemia may cause tiredness and a decreased ability to work and exercise. Unexplained weight loss is also a symptom. […] Achieving a complete cure of bowel cancer usually depends on detecting it early on and if people wait too long before reporting symptoms, the opportunity to completely remove the cancer may be lost. An early diagnosis can also be made if you don’t have symptoms by using screening.
  • #2 Small Intestine Cancer: Symptoms, Types, and Treatment
    https://www.healthline.com/health/small-intestine-cancer
    Small intestine cancer is a rare disease that causes cells in your intestinal tissues to become malignant. Left untreated, small intestine cancer can be life-threatening and can spread to other areas of the body. […] Your outlook depends on the type of small intestine cancer you develop, and whether it can be removed, has spread beyond the small intestine, or is recurrent. […] Early detection allows doctors to find the best course of treatment for your condition. If you begin experiencing irregular symptoms or if you have a history of intestinal cancer, schedule a visit with your doctor.
  • #3 Small Intestine Cancer : Symptoms, Signs and Causes | HCG
    https://www.hcgoncology.com/types-of-cancers/small-intestine-cancer-symptoms-and-causes/
    In many cases, patients may not experience any small intestine cancer symptoms in the early stages. These symptoms also overlap with those of the other less serious conditions. This also contributes to a delayed diagnosis. […] For the effective management of small intestine cancer, it is important for one to not ignore any persistent signs and symptoms related to the abdominal region and seek medical attention whenever necessary. […] Small intestine carcinoma exhibits various symptoms. Any symptom related to the abdominal region, especially if it is persistent, should be checked by a specialist for proper evaluation. The following are the different small intestine cancer symptoms: […] Persistent abdominal pain or cramps is one of the most common small intestine cancer symptoms. The discomfort can be vague initially, making it essential to seek medical attention for a thorough evaluation if symptoms persist.
  • #3 Bowel (Colon) Cancer | Causes, Symptoms, Effects & Treatment | Guts UK
    https://gutscharity.org.uk/advice-and-information/conditions/bowel-cancer/
    As the tumour advances, it grows through the wall of the bowel to invade nearby tissues. Via the blood and lymphatic systems it can spread to other areas of the body. […] The most common areas for secondary bowel cancer to have spread to are the liver and the lungs. This may have already happened when the cancer is first diagnosed, or may happen later. We call these ‘secondaries’ or, more technically, ‘metastases’.