Materiały źródłowe

• #1 Ovarian Cancer Treatment | How to Treat Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating.html

  If youve been diagnosed with ovarian cancer, your cancer care team will discuss your treatment options with you. Its important that you think carefully about each of your choices. Weigh the benefits of each treatment option against the possible risks and side effects. […] Some treatments are local, meaning they treat the tumor without affecting the rest of the body. […] Types of local therapy used for ovarian cancer include: Surgery for Ovarian Cancer, Radiation Therapy for Ovarian Cancer. […] Drugs used to treat ovarian cancer are considered systemic therapies because they can reach cancer cells almost anywhere in the body. They can be given by mouth or put directly into the bloodstream. […] Depending on the type of ovarian cancer, different types of drug treatment might be used, including: Chemotherapy for Ovarian Cancer, Hormone Therapy for Ovarian Cancer, Targeted Drug Therapy for Ovarian Cancer, Immunotherapy for Ovarian Cancer.

• #2 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Treatment of ovarian cancer usually involves a combination of surgery and chemotherapy. Other treatments may be used in certain situations. […] Operations to remove ovarian cancer include: […] Surgery to remove one ovary. For early-stage cancer that hasn’t spread beyond one ovary, surgery may involve removing the affected ovary and its fallopian tube. This procedure may preserve your ability to have children. […] Surgery to remove both ovaries. If cancer is present in both your ovaries, but there are no signs of additional cancer, your surgeon may remove both ovaries and both fallopian tubes. This procedure leaves your uterus intact, so you may still be able to become pregnant using your own frozen embryos or eggs or with eggs from a donor. […] Surgery to remove both ovaries and the uterus. If your cancer is more extensive or if you don’t wish to preserve your ability to have children, your surgeon will remove the ovaries, the fallopian tubes, the uterus, nearby lymph nodes and a fold of fatty abdominal tissue (omentum).

• #3 Ovarian Cancer: Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/4447-ovarian-cancer

  Ovarian cancer is sometimes difficult to detect because symptoms often dont develop until later stages. Healthcare providers treat ovarian cancer with surgery, chemotherapy and other cancer treatments. […] The goal in treating cancer is to remove as much, if not all, cancer from your body as possible. Common ovarian cancer treatments include: Surgery. This typically involves the removal of your reproductive organs and any organ that has cancer on it. Your surgeon may use laparoscopy (a minimally invasive surgery) or laparotomy (open surgery that requires an abdominal incision). […] Chemotherapy. Your provider may recommend chemotherapy either before or after surgery. Chemotherapy are drugs designed to target and kill cancerous cells. Your provider may give you chemotherapy intravenously (through a vein) or orally (in pill form).

• #4 Ovarian Cancer Treatment | How to Treat Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating.html

  Typically, treatment plans are based on the type of ovarian cancer, its stage, and any special situations. Most women with ovarian cancer will have some type of surgery to remove the tumor. […] Depending on the type of ovarian cancer and how advanced it is, you might need other types of treatment as well, either before or after surgery, or sometimes both. […] Based on your treatment options, you might have different types of doctors on your treatment team. […] Your treatment plan will depend on many factors, including your overall health, personal preferences, and whether you plan to have children. […] Its important to discuss all of your treatment options, including their goals and possible side effects, with your doctors to help make the decision that best fits your needs. […] Clinical trials are carefully controlled research studies that are done to get a closer look at promising new treatments or procedures.

• #5 5 Innovative Ovarian Cancer Treatment Options | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/ovarian-cancer/ovarian-cancer-treatment.html

  Surgery, followed by chemotherapy, is a common treatment for ovarian cancer. One or more of the following therapies may be recommended to treat ovarian cancer or help relieve symptoms. […] Surgery is the main treatment for ovarian cancer. Often, ovarian cancer surgery is done to remove or biopsy a mass to find out if it is cancer. […] Once cancer is confirmed, the surgeon stages the cancer based on how far it has spread from the ovaries. […] If the disease seems to be limited to one or both ovaries, the surgeon may immediately remove the ovarian cancer and will biopsy the pelvis and abdomen to find out if the cancer has spread. […] It is often obvious during the surgery whether ovarian cancer has spread; if it has, the surgeon will remove as much of the tumor as possible. This may help other treatments work better. This is called debulking.

• #6 Treatment of Ovarian Cancer | Ovarian Cancer | CDC

  https://www.cdc.gov/ovarian-cancer/treatment/index.html

  Treatment for ovarian cancer usually involves a combination of surgery and chemotherapy. […] If your doctor says that you have ovarian or fallopian tube cancer, ask to be referred to a gynecologic oncologist. […] This doctor will work with you to create a treatment plan. […] Treatment for ovarian cancer usually involves a combination of surgery and chemotherapy. […] Surgery: An operation in which doctors cut out the cancer. […] Chemotherapy: Use of special medicines to shrink or kill the cancer. The drugs can be pills you take or medicines given in your veins, or sometimes both. […] Targeted therapy: Use of drugs to block the growth and spread of cancer cells. The drugs can be pills you take or medicines given in your veins. You will get tests to see if targeted therapy is right for your cancer type before this treatment is used.

• #7 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Treatment of ovarian cancer usually involves a combination of surgery and chemotherapy. Other treatments may be used in certain situations. […] Operations to remove ovarian cancer include: […] Surgery to remove one ovary. For early-stage cancer that hasn’t spread beyond one ovary, surgery may involve removing the affected ovary and its fallopian tube. This procedure may preserve your ability to have children. […] Surgery to remove both ovaries. If cancer is present in both your ovaries, but there are no signs of additional cancer, your surgeon may remove both ovaries and both fallopian tubes. This procedure leaves your uterus intact, so you may still be able to become pregnant using your own frozen embryos or eggs or with eggs from a donor. […] Surgery to remove both ovaries and the uterus. If your cancer is more extensive or if you don’t wish to preserve your ability to have children, your surgeon will remove the ovaries, the fallopian tubes, the uterus, nearby lymph nodes and a fold of fatty abdominal tissue (omentum).

• #8 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Treatment of ovarian cancer usually involves a combination of surgery and chemotherapy. Other treatments may be used in certain situations. […] Operations to remove ovarian cancer include: […] Surgery to remove one ovary. For early-stage cancer that hasn’t spread beyond one ovary, surgery may involve removing the affected ovary and its fallopian tube. This procedure may preserve your ability to have children. […] Surgery to remove both ovaries. If cancer is present in both your ovaries, but there are no signs of additional cancer, your surgeon may remove both ovaries and both fallopian tubes. This procedure leaves your uterus intact, so you may still be able to become pregnant using your own frozen embryos or eggs or with eggs from a donor. […] Surgery to remove both ovaries and the uterus. If your cancer is more extensive or if you don’t wish to preserve your ability to have children, your surgeon will remove the ovaries, the fallopian tubes, the uterus, nearby lymph nodes and a fold of fatty abdominal tissue (omentum).

• #9 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Treatment of ovarian cancer usually involves a combination of surgery and chemotherapy. Other treatments may be used in certain situations. […] Operations to remove ovarian cancer include: […] Surgery to remove one ovary. For early-stage cancer that hasn’t spread beyond one ovary, surgery may involve removing the affected ovary and its fallopian tube. This procedure may preserve your ability to have children. […] Surgery to remove both ovaries. If cancer is present in both your ovaries, but there are no signs of additional cancer, your surgeon may remove both ovaries and both fallopian tubes. This procedure leaves your uterus intact, so you may still be able to become pregnant using your own frozen embryos or eggs or with eggs from a donor. […] Surgery to remove both ovaries and the uterus. If your cancer is more extensive or if you don’t wish to preserve your ability to have children, your surgeon will remove the ovaries, the fallopian tubes, the uterus, nearby lymph nodes and a fold of fatty abdominal tissue (omentum).

• #10 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Treatment of ovarian cancer usually involves a combination of surgery and chemotherapy. Other treatments may be used in certain situations. […] Operations to remove ovarian cancer include: […] Surgery to remove one ovary. For early-stage cancer that hasn’t spread beyond one ovary, surgery may involve removing the affected ovary and its fallopian tube. This procedure may preserve your ability to have children. […] Surgery to remove both ovaries. If cancer is present in both your ovaries, but there are no signs of additional cancer, your surgeon may remove both ovaries and both fallopian tubes. This procedure leaves your uterus intact, so you may still be able to become pregnant using your own frozen embryos or eggs or with eggs from a donor. […] Surgery to remove both ovaries and the uterus. If your cancer is more extensive or if you don’t wish to preserve your ability to have children, your surgeon will remove the ovaries, the fallopian tubes, the uterus, nearby lymph nodes and a fold of fatty abdominal tissue (omentum).

• #11 Ovarian Cancer: Symptoms, Diagnosis & Treatment

  https://my.clevelandclinic.org/health/diseases/4447-ovarian-cancer

  Ovarian cancer is sometimes difficult to detect because symptoms often dont develop until later stages. Healthcare providers treat ovarian cancer with surgery, chemotherapy and other cancer treatments. […] The goal in treating cancer is to remove as much, if not all, cancer from your body as possible. Common ovarian cancer treatments include: Surgery. This typically involves the removal of your reproductive organs and any organ that has cancer on it. Your surgeon may use laparoscopy (a minimally invasive surgery) or laparotomy (open surgery that requires an abdominal incision). […] Chemotherapy. Your provider may recommend chemotherapy either before or after surgery. Chemotherapy are drugs designed to target and kill cancerous cells. Your provider may give you chemotherapy intravenously (through a vein) or orally (in pill form).

• #12 5 Innovative Ovarian Cancer Treatment Options | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/ovarian-cancer/ovarian-cancer-treatment.html

  When you receive ovarian cancer treatment at MD Anderson, a multidisciplinary team of some of the nations foremost experts customizes your care. This team of specialists communicates and collaborates at every step. They customize your ovarian cancer treatment to be sure you receive the highest chance for successful treatment with the least impact on your body. […] We offer the latest, most advanced therapies, including surgery, chemotherapy, hormonal therapies, targeted therapies and immunotherapies. […] Surgery usually is the first step in treating ovarian cancer. It is crucial that your surgeon be experienced in this delicate procedure. […] Studies have shown that patients with ovarian cancer have better outcomes and better chances for survival when the largest amount possible of the tumor is removed.

• #13 5 Innovative Ovarian Cancer Treatment Options | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/ovarian-cancer/ovarian-cancer-treatment.html

  Surgery, followed by chemotherapy, is a common treatment for ovarian cancer. One or more of the following therapies may be recommended to treat ovarian cancer or help relieve symptoms. […] Surgery is the main treatment for ovarian cancer. Often, ovarian cancer surgery is done to remove or biopsy a mass to find out if it is cancer. […] Once cancer is confirmed, the surgeon stages the cancer based on how far it has spread from the ovaries. […] If the disease seems to be limited to one or both ovaries, the surgeon may immediately remove the ovarian cancer and will biopsy the pelvis and abdomen to find out if the cancer has spread. […] It is often obvious during the surgery whether ovarian cancer has spread; if it has, the surgeon will remove as much of the tumor as possible. This may help other treatments work better. This is called debulking.

• #14 Ovarian Cancer | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/ovarian

  Surgery is the main treatment for ovarian cancer, regardless of whether the disease is early or advanced. The type of surgery you receive depends on several factors, including the type and stage of your cancer, your general health, and whether you plan on having children in the future. Our experts recommend that most women undergo chemotherapy as a preventative measure after surgery. […] We’re recognized internationally as a leader in pioneering new ways to treat ovarian cancer, resulting in optimal outcomes for the 200 new ovarian cancer patients who consult us each year. Memorial Sloan Kettering specialists have vast depth and breadth of experience and are among the best in the world. […] We do many procedures at the Josie Robertson Surgery Center, a state-of-the-art facility for short-stay cancer surgery. This allows our patients to return home as soon as possible either the same day or the next to complete their recovery.

• #15 How We Treat Ovarian Cancer | Dana-Farber Cancer Institute

  https://www.dana-farber.org/cancer-care/types/ovarian-cancer/treatment

  Surgery is the main treatment for ovarian cancer, recommended primarily when the vast majority of the cancer or affected tissue can be removed successfully. […] Our surgical team is recognized internationally as one of the best for the treatment of gynecologic cancers, and consistently ranks as one of the top in the country for surgical care. […] Chemotherapy for ovarian cancer may be administered at any stage, but it is usually given at the later stages of the disease. […] Throughout your treatment, your medical oncologist will work closely with your team of nurses, nutritionists, and social workers to minimize the toxicities and side effects of chemotherapy, maintain your quality of life, and optimize your results. […] Intraperitoneal (IP) chemotherapy is an advanced treatment for ovarian cancer that has already spread within the abdominal cavity.

• #16 Treatments for ovarian cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/ovarian/treatment

  If you have ovarian cancer, your healthcare team will create a treatment plan just for you. It will be based on your health and specific information about the cancer. When deciding which treatments to offer for ovarian cancer, your healthcare team will consider: […] Surgery is the primary treatment for all types of ovarian cancer. The type of surgery depends mainly on the type of the tumour and stage of the cancer. […] Chemotherapy may be given after surgery for some types of ovarian cancer. […] Radiation therapy uses high-energy rays or particles to destroy cancer cells. Radiation is rarely used to treat ovarian cancer. […] Hormone therapy is a systemic therapy that slows the growth and spread of ovarian cancer cells by changing hormone levels in the body. […] Some women with ovarian cancer have targeted therapy. It uses drugs to target specific molecules (such as proteins) on cancer cells or inside them. […] Ovarian cancer is sometimes treated with immunotherapy. It helps strengthen the immune system to fight cancer. […] Women with ovarian cancer should talk to their doctor about a follow-up plan that suits their individual situation.

• #17 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Surgery for advanced cancer. If your cancer is advanced, your doctor may recommend surgery to remove as much of the cancer as possible. Sometimes chemotherapy is given before or after surgery in this situation. […] Chemotherapy is a drug treatment that uses chemicals to kill fast-growing cells in the body, including cancer cells. Chemotherapy drugs can be injected into a vein or taken by mouth. […] Chemotherapy is often used after surgery to kill any cancer cells that might remain. It can also be used before surgery. […] In certain situations, chemotherapy drugs may be heated and infused into the abdomen during surgery (hyperthermic intraperitoneal chemotherapy). The drugs are left in place for a certain amount of time before they’re drained. Then the operation is completed. […] Targeted drug treatments focus on specific weaknesses present within cancer cells. By attacking these weaknesses, targeted drug treatments can cause cancer cells to die.

• #18 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Surgery for advanced cancer. If your cancer is advanced, your doctor may recommend surgery to remove as much of the cancer as possible. Sometimes chemotherapy is given before or after surgery in this situation. […] Chemotherapy is a drug treatment that uses chemicals to kill fast-growing cells in the body, including cancer cells. Chemotherapy drugs can be injected into a vein or taken by mouth. […] Chemotherapy is often used after surgery to kill any cancer cells that might remain. It can also be used before surgery. […] In certain situations, chemotherapy drugs may be heated and infused into the abdomen during surgery (hyperthermic intraperitoneal chemotherapy). The drugs are left in place for a certain amount of time before they’re drained. Then the operation is completed. […] Targeted drug treatments focus on specific weaknesses present within cancer cells. By attacking these weaknesses, targeted drug treatments can cause cancer cells to die.

• #19 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Surgery for advanced cancer. If your cancer is advanced, your doctor may recommend surgery to remove as much of the cancer as possible. Sometimes chemotherapy is given before or after surgery in this situation. […] Chemotherapy is a drug treatment that uses chemicals to kill fast-growing cells in the body, including cancer cells. Chemotherapy drugs can be injected into a vein or taken by mouth. […] Chemotherapy is often used after surgery to kill any cancer cells that might remain. It can also be used before surgery. […] In certain situations, chemotherapy drugs may be heated and infused into the abdomen during surgery (hyperthermic intraperitoneal chemotherapy). The drugs are left in place for a certain amount of time before they’re drained. Then the operation is completed. […] Targeted drug treatments focus on specific weaknesses present within cancer cells. By attacking these weaknesses, targeted drug treatments can cause cancer cells to die.

• #20 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Surgery for advanced cancer. If your cancer is advanced, your doctor may recommend surgery to remove as much of the cancer as possible. Sometimes chemotherapy is given before or after surgery in this situation. […] Chemotherapy is a drug treatment that uses chemicals to kill fast-growing cells in the body, including cancer cells. Chemotherapy drugs can be injected into a vein or taken by mouth. […] Chemotherapy is often used after surgery to kill any cancer cells that might remain. It can also be used before surgery. […] In certain situations, chemotherapy drugs may be heated and infused into the abdomen during surgery (hyperthermic intraperitoneal chemotherapy). The drugs are left in place for a certain amount of time before they’re drained. Then the operation is completed. […] Targeted drug treatments focus on specific weaknesses present within cancer cells. By attacking these weaknesses, targeted drug treatments can cause cancer cells to die.

• #21 How We Treat Ovarian Cancer | Dana-Farber Cancer Institute

  https://www.dana-farber.org/cancer-care/types/ovarian-cancer/treatment

  Hyperthermic intraperitoneal chemotherapy (HIPEC) involves a single use of heated chemotherapy in the abdomen, given at the time of surgery. […] Radiation therapy for ovarian cancer is given by our experienced team of radiation oncologists. […] Radiation therapy is used to treat select cases of ovarian cancer. […] Patients at Dana-Farber have access to one of the largest and most active clinical trial programs available, including clinical trials for patients with ovarian cancer. […] Clinical trials may include biologic therapies or treatments that use the patient’s immune system to fight the cancer.

• #22 Treatment for Ovarian Cancer | Fred Hutchinson Cancer Center

  https://www.fredhutch.org/en/diseases/ovarian-cancer/treatment.html

  Chemotherapy works by killing fast-growing cells, but the drugs cannot discriminate between cancer cells and other fast-growing cells such as hair follicles. […] You will probably receive a combination of two chemotherapy drugs. The standard chemotherapy for ovarian cancer is a combination of paclitaxel (Taxol) plus either carboplatin (Paraplatin) or cisplatin (Platinol). […] Surgery is the standard treatment for ovarian cancer. […] If your cancer has spread beyond your ovary, your doctors may recommend following your surgery with chemotherapy. […] Studies show that outcomes are better for women whose surgery is performed by a gynecologic oncologist. […] If ovarian cancer is suspected, your gynecologic oncologist will recommend an exploratory surgery. […] If there is cancer elsewhere in the abdomen, your doctor will remove as much of the tumor as possible, a procedure that is called „debulking.”

• #23 Treatments for epithelial ovarian cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/ovarian/treatment/epithelial-ovarian-cancer

  The following are treatment options for the stages of epithelial ovarian cancer. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan. […] Surgery is the first treatment given for stage 1 epithelial ovarian cancer. It is done to remove the cancer and to see if there is any spread outside of the ovaries. […] Chemotherapy may be given after surgery for stage 1 epithelial ovarian cancer. […] A combination of a platinum drug, such as cisplatin or carboplatin, and a taxane drug, such as paclitaxel or docetaxel, is used. […] Stage 1C treatment is surgery followed by chemotherapy. […] Surgery is the first treatment given for stage 2 epithelial ovarian cancer. […] Chemotherapy is usually given following surgery. […] Surgery is the first treatment given for stage 3 epithelial ovarian cancer.

• #24 Chemotherapy for Ovarian Cancer: FAQs, Complementary Therapy, and Medication

  https://www.webmd.com/ovarian-cancer/14-facts-chemo-ovarian-cancer

  Chemotherapy is usually recommended after surgery for most stages of ovarian cancer. A combination of chemotherapy medications is typically used. The primary goal of chemotherapy is to destroy cancer cells by preventing them from growing and dividing rapidly and to bring about cancer remission. […] An oncologist, or cancer doctor, oversees and prescribes the treatment. A nurse may administer the chemotherapy medications into a vein (intravenous (IV). People with advanced ovarian cancer may have intraperitoneal (IP) chemotherapy, where medications are injected through a catheter or port in your abdomen. […] The number of treatment cycles, or doses, you have will depend on the stage of your disease. A cycle is a schedule that allows regular doses of a drug, followed by a rest period. For example, if you have advanced ovarian cancer, you may get a course of chemotherapy every three weeks for six doses. Different drugs have varying cycles; your oncologist will prescribe the particular cycle or schedule for your chemotherapy.

• #25 Chemotherapy for Ovarian Cancer: FAQs, Complementary Therapy, and Medication

  https://www.webmd.com/ovarian-cancer/14-facts-chemo-ovarian-cancer

  Chemotherapy is usually recommended after surgery for most stages of ovarian cancer. A combination of chemotherapy medications is typically used. The primary goal of chemotherapy is to destroy cancer cells by preventing them from growing and dividing rapidly and to bring about cancer remission. […] An oncologist, or cancer doctor, oversees and prescribes the treatment. A nurse may administer the chemotherapy medications into a vein (intravenous (IV). People with advanced ovarian cancer may have intraperitoneal (IP) chemotherapy, where medications are injected through a catheter or port in your abdomen. […] The number of treatment cycles, or doses, you have will depend on the stage of your disease. A cycle is a schedule that allows regular doses of a drug, followed by a rest period. For example, if you have advanced ovarian cancer, you may get a course of chemotherapy every three weeks for six doses. Different drugs have varying cycles; your oncologist will prescribe the particular cycle or schedule for your chemotherapy.

• #26 Chemotherapy for Ovarian Cancer: FAQs, Complementary Therapy, and Medication

  https://www.webmd.com/ovarian-cancer/14-facts-chemo-ovarian-cancer

  Side effects like tingling or numbness in the hands and feet may be permanent, because some of the drugs used to treat ovarian cancer may cause nerve damage. Therefore, it is important to let your oncologist know right away if you are experiencing these symptoms. […] Your oncologist may prescribe medications to prevent side effects like nausea and vomiting. Talk to your oncologist about your options. Oncology social workers and oncology nurses can also help you manage fatigue. Patient guides, such as the American Cancer Society’s „Managing Side Effects,” can also give practical tips for dealing with chemotherapy-related side effects. […] Yes, temporary side effects like nausea, vomiting, hair loss, and fatigue usually go away following the completion of treatment. […] Your oncologist will monitor your progress at each chemotherapy appointment. After the successful completion of chemotherapy, you usually will see your oncologist every 2-4 months for the first two years, every 3-6 months for the next three years, and then once a year after that. However, your follow-up schedule will largely be determined by your cancer and how you responded to treatment.

• #27 Chemotherapy for Ovarian Cancer: FAQs, Complementary Therapy, and Medication

  https://www.webmd.com/ovarian-cancer/14-facts-chemo-ovarian-cancer

  Side effects like tingling or numbness in the hands and feet may be permanent, because some of the drugs used to treat ovarian cancer may cause nerve damage. Therefore, it is important to let your oncologist know right away if you are experiencing these symptoms. […] Your oncologist may prescribe medications to prevent side effects like nausea and vomiting. Talk to your oncologist about your options. Oncology social workers and oncology nurses can also help you manage fatigue. Patient guides, such as the American Cancer Society’s „Managing Side Effects,” can also give practical tips for dealing with chemotherapy-related side effects. […] Yes, temporary side effects like nausea, vomiting, hair loss, and fatigue usually go away following the completion of treatment. […] Your oncologist will monitor your progress at each chemotherapy appointment. After the successful completion of chemotherapy, you usually will see your oncologist every 2-4 months for the first two years, every 3-6 months for the next three years, and then once a year after that. However, your follow-up schedule will largely be determined by your cancer and how you responded to treatment.

• #28 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Targeted therapy is a type of cancer treatment that uses drugs to attack parts of cancer cells that make them different from normal, healthy cells. Each type of targeted therapy works differently, but they all change the way a cancer cell grows, divides, repairs itself, or interacts with other cells. […] Bevacizumab has been shown to shrink or slow the growth of advanced epithelial ovarian cancers. Bevacizumab appears to work even better when given along with chemotherapy having shown good results in terms of shrinking (or stopping the growth of) tumors. But it doesnt seem to help women live longer. […] Olaparib (Lynparza) is used to treat advanced ovarian cancer, typically after chemotherapy has been tried. This drug can be used in patients with or without mutations in one of the BRCA genes.

• #29 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Surgery for advanced cancer. If your cancer is advanced, your doctor may recommend surgery to remove as much of the cancer as possible. Sometimes chemotherapy is given before or after surgery in this situation. […] Chemotherapy is a drug treatment that uses chemicals to kill fast-growing cells in the body, including cancer cells. Chemotherapy drugs can be injected into a vein or taken by mouth. […] Chemotherapy is often used after surgery to kill any cancer cells that might remain. It can also be used before surgery. […] In certain situations, chemotherapy drugs may be heated and infused into the abdomen during surgery (hyperthermic intraperitoneal chemotherapy). The drugs are left in place for a certain amount of time before they’re drained. Then the operation is completed. […] Targeted drug treatments focus on specific weaknesses present within cancer cells. By attacking these weaknesses, targeted drug treatments can cause cancer cells to die.

• #30 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Targeted therapy is a type of cancer treatment that uses drugs to attack parts of cancer cells that make them different from normal, healthy cells. Each type of targeted therapy works differently, but they all change the way a cancer cell grows, divides, repairs itself, or interacts with other cells. […] Bevacizumab has been shown to shrink or slow the growth of advanced epithelial ovarian cancers. Bevacizumab appears to work even better when given along with chemotherapy having shown good results in terms of shrinking (or stopping the growth of) tumors. But it doesnt seem to help women live longer. […] Olaparib (Lynparza) is used to treat advanced ovarian cancer, typically after chemotherapy has been tried. This drug can be used in patients with or without mutations in one of the BRCA genes.

• #31 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Targeted therapy is a type of cancer treatment that uses drugs to attack parts of cancer cells that make them different from normal, healthy cells. Each type of targeted therapy works differently, but they all change the way a cancer cell grows, divides, repairs itself, or interacts with other cells. […] Bevacizumab has been shown to shrink or slow the growth of advanced epithelial ovarian cancers. Bevacizumab appears to work even better when given along with chemotherapy having shown good results in terms of shrinking (or stopping the growth of) tumors. But it doesnt seem to help women live longer. […] Olaparib (Lynparza) is used to treat advanced ovarian cancer, typically after chemotherapy has been tried. This drug can be used in patients with or without mutations in one of the BRCA genes.

• #32 Targeted Therapies for Ovarian Cancer | Ovarian Cancer Treatments | Ovarian Cancer Action

  https://ovarian.org.uk/ovarian-cancer/living-with-ovarian-cancer/ovarian-cancer-treatment/targeted-therapies-for-ovarian-cancer/

  Targeted therapies for ovarian cancer. […] Targeted cancer therapies are drugs that stop the spread of cancer by identifying and blocking the genetic changes responsible for the cancers growth and progression. […] There are different targeted therapies available to women with ovarian cancer. […] Avastin (the brand name of the drug Bevacizumab) belongs to a group of treatments called anti-angiogenics. […] In England, Avastin is used to treat first-line ovarian cancer following the standard treatment combination of Carboplatin and Paxitaxol. […] In Scotland, Avastin is available for women with recurrent, platinum resistant ovarian cancer. […] PARP inhibitors are a new class of targeted cancer drug that is becoming more common in ovarian cancer treatment. […] There are currently three PARP inhibitors available to treat ovarian cancer: olaparib, niraparib and rucaparib.

• #33 Targeted Therapies for Ovarian Cancer | Ovarian Cancer Treatments | Ovarian Cancer Action

  https://ovarian.org.uk/ovarian-cancer/living-with-ovarian-cancer/ovarian-cancer-treatment/targeted-therapies-for-ovarian-cancer/

  Targeted therapies for ovarian cancer. […] Targeted cancer therapies are drugs that stop the spread of cancer by identifying and blocking the genetic changes responsible for the cancers growth and progression. […] There are different targeted therapies available to women with ovarian cancer. […] Avastin (the brand name of the drug Bevacizumab) belongs to a group of treatments called anti-angiogenics. […] In England, Avastin is used to treat first-line ovarian cancer following the standard treatment combination of Carboplatin and Paxitaxol. […] In Scotland, Avastin is available for women with recurrent, platinum resistant ovarian cancer. […] PARP inhibitors are a new class of targeted cancer drug that is becoming more common in ovarian cancer treatment. […] There are currently three PARP inhibitors available to treat ovarian cancer: olaparib, niraparib and rucaparib.

• #34 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Targeted therapy is a type of cancer treatment that uses drugs to attack parts of cancer cells that make them different from normal, healthy cells. Each type of targeted therapy works differently, but they all change the way a cancer cell grows, divides, repairs itself, or interacts with other cells. […] Bevacizumab has been shown to shrink or slow the growth of advanced epithelial ovarian cancers. Bevacizumab appears to work even better when given along with chemotherapy having shown good results in terms of shrinking (or stopping the growth of) tumors. But it doesnt seem to help women live longer. […] Olaparib (Lynparza) is used to treat advanced ovarian cancer, typically after chemotherapy has been tried. This drug can be used in patients with or without mutations in one of the BRCA genes.

• #35 Promising new drugs and therapeutic approaches for treatment of ovarian cancer—targeting the hallmarks of cancer | BMC Medicine | Full Text

  https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03826-w

  PARPi are highly efficient in OC. Among others, PARPi inhibit repair of DNA single-strand breaks and thereby cause accumulation of DNA double-strand breaks. Deficiency of high-quality HR and concurrent inhibition of alternative end joining (alt-EJ) by PARPi, as well as dependency on more error-prone non-homologous end joining (NHEJ) to repair DSBs, leads to accumulation of mutations, unregulated cell division, and apoptosis. […] Thus, today PARPi are considered as first-line standard of care maintenance therapy of OC after response to platinum-based therapy. Based on several phase III studies, investigating olaparib, niraparib, and rucaparib in first-line setting, including SOLO-1, PRIMA, and ATHENA trial which have been reviewed in detail elsewhere, olaparib is approved for first-line maintenance treatment of advanced OC with BRCAm; niraparib is approved regardless of HRD status.

• #36 Targeted Therapies for Ovarian Cancer | Ovarian Cancer Treatments | Ovarian Cancer Action

  https://ovarian.org.uk/ovarian-cancer/living-with-ovarian-cancer/ovarian-cancer-treatment/targeted-therapies-for-ovarian-cancer/

  Targeted therapies for ovarian cancer. […] Targeted cancer therapies are drugs that stop the spread of cancer by identifying and blocking the genetic changes responsible for the cancers growth and progression. […] There are different targeted therapies available to women with ovarian cancer. […] Avastin (the brand name of the drug Bevacizumab) belongs to a group of treatments called anti-angiogenics. […] In England, Avastin is used to treat first-line ovarian cancer following the standard treatment combination of Carboplatin and Paxitaxol. […] In Scotland, Avastin is available for women with recurrent, platinum resistant ovarian cancer. […] PARP inhibitors are a new class of targeted cancer drug that is becoming more common in ovarian cancer treatment. […] There are currently three PARP inhibitors available to treat ovarian cancer: olaparib, niraparib and rucaparib.

• #37 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Olaparib can be used as maintenance treatment for advanced ovarian cancer that has gotten smaller in response to first treatment with chemotherapy containing cisplatin or carboplatin. […] Niraparib (Zejula) may be used in some situations to treat ovarian cancer. […] Rucaparib (Rubraca) can be used in women with or without a BRCA mutation, as maintenance treatment for advanced ovarian cancer that has come back after treatment, and then has shrunk in response to chemotherapy containing cisplatin or carboplatin. […] These drugs have been shown to help shrink or slow the growth of some advanced ovarian cancers for a time. So far, though, it’s not clear if they can help women live longer. […] Mirvetuximab soravtansine (Elahere) is an antibody-drug conjugate (ADC), which is a lab-made antibody linked to a chemotherapy drug. This drug can be used to treat epithelial ovarian cancer that tests positive for FR-alpha and that is no longer responding to platinum chemotherapy drugs such as cisplatin or carboplatin. […] Larotrectinib (Vitrakvi) and entrectinib (Rozlytrek) are targeted drugs that stop the proteins made by the abnormal NTRK genes. These drugs can be used in people with advanced ovarian cancer whose tumor has an NTRK gene change and is still growing despite other treatments.

• #38 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Olaparib can be used as maintenance treatment for advanced ovarian cancer that has gotten smaller in response to first treatment with chemotherapy containing cisplatin or carboplatin. […] Niraparib (Zejula) may be used in some situations to treat ovarian cancer. […] Rucaparib (Rubraca) can be used in women with or without a BRCA mutation, as maintenance treatment for advanced ovarian cancer that has come back after treatment, and then has shrunk in response to chemotherapy containing cisplatin or carboplatin. […] These drugs have been shown to help shrink or slow the growth of some advanced ovarian cancers for a time. So far, though, it’s not clear if they can help women live longer. […] Mirvetuximab soravtansine (Elahere) is an antibody-drug conjugate (ADC), which is a lab-made antibody linked to a chemotherapy drug. This drug can be used to treat epithelial ovarian cancer that tests positive for FR-alpha and that is no longer responding to platinum chemotherapy drugs such as cisplatin or carboplatin. […] Larotrectinib (Vitrakvi) and entrectinib (Rozlytrek) are targeted drugs that stop the proteins made by the abnormal NTRK genes. These drugs can be used in people with advanced ovarian cancer whose tumor has an NTRK gene change and is still growing despite other treatments.

• #39 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Olaparib can be used as maintenance treatment for advanced ovarian cancer that has gotten smaller in response to first treatment with chemotherapy containing cisplatin or carboplatin. […] Niraparib (Zejula) may be used in some situations to treat ovarian cancer. […] Rucaparib (Rubraca) can be used in women with or without a BRCA mutation, as maintenance treatment for advanced ovarian cancer that has come back after treatment, and then has shrunk in response to chemotherapy containing cisplatin or carboplatin. […] These drugs have been shown to help shrink or slow the growth of some advanced ovarian cancers for a time. So far, though, it’s not clear if they can help women live longer. […] Mirvetuximab soravtansine (Elahere) is an antibody-drug conjugate (ADC), which is a lab-made antibody linked to a chemotherapy drug. This drug can be used to treat epithelial ovarian cancer that tests positive for FR-alpha and that is no longer responding to platinum chemotherapy drugs such as cisplatin or carboplatin. […] Larotrectinib (Vitrakvi) and entrectinib (Rozlytrek) are targeted drugs that stop the proteins made by the abnormal NTRK genes. These drugs can be used in people with advanced ovarian cancer whose tumor has an NTRK gene change and is still growing despite other treatments.

• #40 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Olaparib can be used as maintenance treatment for advanced ovarian cancer that has gotten smaller in response to first treatment with chemotherapy containing cisplatin or carboplatin. […] Niraparib (Zejula) may be used in some situations to treat ovarian cancer. […] Rucaparib (Rubraca) can be used in women with or without a BRCA mutation, as maintenance treatment for advanced ovarian cancer that has come back after treatment, and then has shrunk in response to chemotherapy containing cisplatin or carboplatin. […] These drugs have been shown to help shrink or slow the growth of some advanced ovarian cancers for a time. So far, though, it’s not clear if they can help women live longer. […] Mirvetuximab soravtansine (Elahere) is an antibody-drug conjugate (ADC), which is a lab-made antibody linked to a chemotherapy drug. This drug can be used to treat epithelial ovarian cancer that tests positive for FR-alpha and that is no longer responding to platinum chemotherapy drugs such as cisplatin or carboplatin. […] Larotrectinib (Vitrakvi) and entrectinib (Rozlytrek) are targeted drugs that stop the proteins made by the abnormal NTRK genes. These drugs can be used in people with advanced ovarian cancer whose tumor has an NTRK gene change and is still growing despite other treatments.

• #41 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Olaparib can be used as maintenance treatment for advanced ovarian cancer that has gotten smaller in response to first treatment with chemotherapy containing cisplatin or carboplatin. […] Niraparib (Zejula) may be used in some situations to treat ovarian cancer. […] Rucaparib (Rubraca) can be used in women with or without a BRCA mutation, as maintenance treatment for advanced ovarian cancer that has come back after treatment, and then has shrunk in response to chemotherapy containing cisplatin or carboplatin. […] These drugs have been shown to help shrink or slow the growth of some advanced ovarian cancers for a time. So far, though, it’s not clear if they can help women live longer. […] Mirvetuximab soravtansine (Elahere) is an antibody-drug conjugate (ADC), which is a lab-made antibody linked to a chemotherapy drug. This drug can be used to treat epithelial ovarian cancer that tests positive for FR-alpha and that is no longer responding to platinum chemotherapy drugs such as cisplatin or carboplatin. […] Larotrectinib (Vitrakvi) and entrectinib (Rozlytrek) are targeted drugs that stop the proteins made by the abnormal NTRK genes. These drugs can be used in people with advanced ovarian cancer whose tumor has an NTRK gene change and is still growing despite other treatments.

• #42 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Olaparib can be used as maintenance treatment for advanced ovarian cancer that has gotten smaller in response to first treatment with chemotherapy containing cisplatin or carboplatin. […] Niraparib (Zejula) may be used in some situations to treat ovarian cancer. […] Rucaparib (Rubraca) can be used in women with or without a BRCA mutation, as maintenance treatment for advanced ovarian cancer that has come back after treatment, and then has shrunk in response to chemotherapy containing cisplatin or carboplatin. […] These drugs have been shown to help shrink or slow the growth of some advanced ovarian cancers for a time. So far, though, it’s not clear if they can help women live longer. […] Mirvetuximab soravtansine (Elahere) is an antibody-drug conjugate (ADC), which is a lab-made antibody linked to a chemotherapy drug. This drug can be used to treat epithelial ovarian cancer that tests positive for FR-alpha and that is no longer responding to platinum chemotherapy drugs such as cisplatin or carboplatin. […] Larotrectinib (Vitrakvi) and entrectinib (Rozlytrek) are targeted drugs that stop the proteins made by the abnormal NTRK genes. These drugs can be used in people with advanced ovarian cancer whose tumor has an NTRK gene change and is still growing despite other treatments.

• #43 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Olaparib can be used as maintenance treatment for advanced ovarian cancer that has gotten smaller in response to first treatment with chemotherapy containing cisplatin or carboplatin. […] Niraparib (Zejula) may be used in some situations to treat ovarian cancer. […] Rucaparib (Rubraca) can be used in women with or without a BRCA mutation, as maintenance treatment for advanced ovarian cancer that has come back after treatment, and then has shrunk in response to chemotherapy containing cisplatin or carboplatin. […] These drugs have been shown to help shrink or slow the growth of some advanced ovarian cancers for a time. So far, though, it’s not clear if they can help women live longer. […] Mirvetuximab soravtansine (Elahere) is an antibody-drug conjugate (ADC), which is a lab-made antibody linked to a chemotherapy drug. This drug can be used to treat epithelial ovarian cancer that tests positive for FR-alpha and that is no longer responding to platinum chemotherapy drugs such as cisplatin or carboplatin. […] Larotrectinib (Vitrakvi) and entrectinib (Rozlytrek) are targeted drugs that stop the proteins made by the abnormal NTRK genes. These drugs can be used in people with advanced ovarian cancer whose tumor has an NTRK gene change and is still growing despite other treatments.

• #44 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Olaparib can be used as maintenance treatment for advanced ovarian cancer that has gotten smaller in response to first treatment with chemotherapy containing cisplatin or carboplatin. […] Niraparib (Zejula) may be used in some situations to treat ovarian cancer. […] Rucaparib (Rubraca) can be used in women with or without a BRCA mutation, as maintenance treatment for advanced ovarian cancer that has come back after treatment, and then has shrunk in response to chemotherapy containing cisplatin or carboplatin. […] These drugs have been shown to help shrink or slow the growth of some advanced ovarian cancers for a time. So far, though, it’s not clear if they can help women live longer. […] Mirvetuximab soravtansine (Elahere) is an antibody-drug conjugate (ADC), which is a lab-made antibody linked to a chemotherapy drug. This drug can be used to treat epithelial ovarian cancer that tests positive for FR-alpha and that is no longer responding to platinum chemotherapy drugs such as cisplatin or carboplatin. […] Larotrectinib (Vitrakvi) and entrectinib (Rozlytrek) are targeted drugs that stop the proteins made by the abnormal NTRK genes. These drugs can be used in people with advanced ovarian cancer whose tumor has an NTRK gene change and is still growing despite other treatments.

• #45

  https://www.facingourrisk.org/info/risk-management-and-treatment/by-cancer-type/fallopian-ovarian-peritoneal/maintenance-therapy

  Maintenance therapy is a type of treatment given to people after they complete chemotherapy treatment to decrease the chance that the cancer will come back. […] Maintenance therapy may be given to some people after they complete chemotherapy treatment to decrease the chance that the cancer will come back, or to delay the cancer from coming back. Two types of targeted therapies are used for maintenance therapy, Avastin (bevacizumab) and PARP inhibitors. […] Avastin (bevacizumab) may be used as maintenance therapy for people who received Avastin with chemotherapy as part of their initial treatment and had a complete or partial response. […] PARP inhibitors are a type of targeted therapy that can be used as treatment or as maintenance after treatment. PARP inhibitors are only used for maintenance therapy to treat people who had a complete or partial response to their most recent treatment with chemotherapy.

• #46

  https://www.facingourrisk.org/info/risk-management-and-treatment/by-cancer-type/fallopian-ovarian-peritoneal/maintenance-therapy

  Maintenance therapy is a type of treatment given to people after they complete chemotherapy treatment to decrease the chance that the cancer will come back. […] Maintenance therapy may be given to some people after they complete chemotherapy treatment to decrease the chance that the cancer will come back, or to delay the cancer from coming back. Two types of targeted therapies are used for maintenance therapy, Avastin (bevacizumab) and PARP inhibitors. […] Avastin (bevacizumab) may be used as maintenance therapy for people who received Avastin with chemotherapy as part of their initial treatment and had a complete or partial response. […] PARP inhibitors are a type of targeted therapy that can be used as treatment or as maintenance after treatment. PARP inhibitors are only used for maintenance therapy to treat people who had a complete or partial response to their most recent treatment with chemotherapy.

• #47

  https://www.facingourrisk.org/info/risk-management-and-treatment/by-cancer-type/fallopian-ovarian-peritoneal/maintenance-therapy

  Maintenance therapy is a type of treatment given to people after they complete chemotherapy treatment to decrease the chance that the cancer will come back. […] Maintenance therapy may be given to some people after they complete chemotherapy treatment to decrease the chance that the cancer will come back, or to delay the cancer from coming back. Two types of targeted therapies are used for maintenance therapy, Avastin (bevacizumab) and PARP inhibitors. […] Avastin (bevacizumab) may be used as maintenance therapy for people who received Avastin with chemotherapy as part of their initial treatment and had a complete or partial response. […] PARP inhibitors are a type of targeted therapy that can be used as treatment or as maintenance after treatment. PARP inhibitors are only used for maintenance therapy to treat people who had a complete or partial response to their most recent treatment with chemotherapy.

• #48

  https://www.facingourrisk.org/info/risk-management-and-treatment/by-cancer-type/fallopian-ovarian-peritoneal/maintenance-therapy

  Maintenance therapy is a type of treatment given to people after they complete chemotherapy treatment to decrease the chance that the cancer will come back. […] Maintenance therapy may be given to some people after they complete chemotherapy treatment to decrease the chance that the cancer will come back, or to delay the cancer from coming back. Two types of targeted therapies are used for maintenance therapy, Avastin (bevacizumab) and PARP inhibitors. […] Avastin (bevacizumab) may be used as maintenance therapy for people who received Avastin with chemotherapy as part of their initial treatment and had a complete or partial response. […] PARP inhibitors are a type of targeted therapy that can be used as treatment or as maintenance after treatment. PARP inhibitors are only used for maintenance therapy to treat people who had a complete or partial response to their most recent treatment with chemotherapy.

• #49 Immunotherapy for Ovarian Cancer | Cancer Research Institute

  https://www.cancerresearch.org/cancer-types/ovarian-cancer

  Immunotherapy for ovarian cancer shows tremendous potential for addressing this devastating disease and several clinical trials testing new treatments are currently underway. […] While significant advances have been made in surgical and chemo-based treatments for ovarian cancer, the survival rates have only modestly improved. […] There is an urgent need for new treatments for advanced stage, recurring ovarian cancer. […] First-line treatment for ovarian cancer includes surgery followed by a chemotherapy regimen combining a platinum-based (usually carboplatin) and a taxane-based (usually paclitaxel) treatment. […] After completion of upfront chemotherapy, patients may be eligible to receive maintenance therapy with a new class of drugs called PARP inhibitors, which have been demonstrated to significantly delay and possibly even prevent disease relapse in some patients, particularly patients whose tumor carry mutations in BRCA1 and BRCA2 genes.

• #50 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  If you’re considering targeted therapy for ovarian cancer, your doctor may test your cancer cells to determine which targeted therapy is most likely to have an effect on your cancer. […] Hormone therapy uses drugs to block the effects of the hormone estrogen on ovarian cancer cells. Some ovarian cancer cells use estrogen to help them grow, so blocking estrogen may help control the cancer. […] Hormone therapy might be a treatment option for some types of slow-growing ovarian cancers. It may also be an option if the cancer comes back after initial treatments. […] Immunotherapy uses the immune system to fight cancer. The body’s disease-fighting immune system may not attack cancer cells because they produce proteins that help them hide from the immune system cells. Immunotherapy works by interfering with that process.

• #51 Immunotherapy for Ovarian Cancer | Cancer Research Institute

  https://www.cancerresearch.org/cancer-types/ovarian-cancer

  Immunotherapy is a class of treatments that take advantage of a person’s own immune system to help kill cancer cells. There are currently three FDA-approved immunotherapy options for ovarian cancer. […] Patients with platinum-resistant, recurrent ovarian cancer, or all stages of ovarian cancer above stage 1/grade 1, should consider entering into immunotherapy clinical trials. […] Since 1985, the Cancer Research Institute has dedicated more than $21 million in grant funding to discover and develop effective immunotherapies to treat ovarian cancer. […] Research findings from leading immunologists continue to demonstrate potential and promise for the future of immune-based treatment for patients with ovarian cancers—bringing hope and optimism for more lifesaving therapies for this formidable disease.

• #52 Ovarian cancer: New treatments and research – Mayo Clinic Comprehensive Cancer Center Blog

  https://cancerblog.mayoclinic.org/2024/05/01/ovarian-cancer-new-treatments-and-research/

  „Pembrolizumab is in a category of drugs called immune checkpoint inhibitors,” says Dr. Weroha. „This drug is designed to release the brakes on the immune system to allow it to do what it naturally wants: kill things it doesn’t like. The hope is that the vaccine combined with the immunotherapy drug will kill a lot of ovarian cancer. It’s exciting research.” […] If you’ve been diagnosed with ovarian cancer, Dr. Weroha recommends making an appointment with a gynecologic oncologist. „A gynecologic oncologist will be up to date on the current treatment recommendations and the management of side effects. That’s important,” he says. […] Dr. Weroha also recommends newly diagnosed patients ask their care teams if they are candidates for PARP inhibitors, mirvetuximab or clinical trials. „PARP inhibitors and mirvetuximab are newer treatments that could influence the outcome of your overall treatment. Always ask about clinical trials because when ovarian cancer recurs, there is no treatment so good that we can stop looking for something better,” he says.

• #53 Ovarian cancer: New treatments and research – Mayo Clinic Comprehensive Cancer Center Blog

  https://cancerblog.mayoclinic.org/2024/05/01/ovarian-cancer-new-treatments-and-research/

  „Pembrolizumab is in a category of drugs called immune checkpoint inhibitors,” says Dr. Weroha. „This drug is designed to release the brakes on the immune system to allow it to do what it naturally wants: kill things it doesn’t like. The hope is that the vaccine combined with the immunotherapy drug will kill a lot of ovarian cancer. It’s exciting research.” […] If you’ve been diagnosed with ovarian cancer, Dr. Weroha recommends making an appointment with a gynecologic oncologist. „A gynecologic oncologist will be up to date on the current treatment recommendations and the management of side effects. That’s important,” he says. […] Dr. Weroha also recommends newly diagnosed patients ask their care teams if they are candidates for PARP inhibitors, mirvetuximab or clinical trials. „PARP inhibitors and mirvetuximab are newer treatments that could influence the outcome of your overall treatment. Always ask about clinical trials because when ovarian cancer recurs, there is no treatment so good that we can stop looking for something better,” he says.

• #54 Ovarian cancer: New treatments and research – Mayo Clinic Comprehensive Cancer Center Blog

  https://cancerblog.mayoclinic.org/2024/05/01/ovarian-cancer-new-treatments-and-research/

  „Pembrolizumab is in a category of drugs called immune checkpoint inhibitors,” says Dr. Weroha. „This drug is designed to release the brakes on the immune system to allow it to do what it naturally wants: kill things it doesn’t like. The hope is that the vaccine combined with the immunotherapy drug will kill a lot of ovarian cancer. It’s exciting research.” […] If you’ve been diagnosed with ovarian cancer, Dr. Weroha recommends making an appointment with a gynecologic oncologist. „A gynecologic oncologist will be up to date on the current treatment recommendations and the management of side effects. That’s important,” he says. […] Dr. Weroha also recommends newly diagnosed patients ask their care teams if they are candidates for PARP inhibitors, mirvetuximab or clinical trials. „PARP inhibitors and mirvetuximab are newer treatments that could influence the outcome of your overall treatment. Always ask about clinical trials because when ovarian cancer recurs, there is no treatment so good that we can stop looking for something better,” he says.

• #55 Immunotherapy for Ovarian Cancer | Cancer Research Institute

  https://www.cancerresearch.org/cancer-types/ovarian-cancer

  Immunotherapy is a class of treatments that take advantage of a person’s own immune system to help kill cancer cells. There are currently three FDA-approved immunotherapy options for ovarian cancer. […] Patients with platinum-resistant, recurrent ovarian cancer, or all stages of ovarian cancer above stage 1/grade 1, should consider entering into immunotherapy clinical trials. […] Since 1985, the Cancer Research Institute has dedicated more than $21 million in grant funding to discover and develop effective immunotherapies to treat ovarian cancer. […] Research findings from leading immunologists continue to demonstrate potential and promise for the future of immune-based treatment for patients with ovarian cancers—bringing hope and optimism for more lifesaving therapies for this formidable disease.

• #56 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  If you’re considering targeted therapy for ovarian cancer, your doctor may test your cancer cells to determine which targeted therapy is most likely to have an effect on your cancer. […] Hormone therapy uses drugs to block the effects of the hormone estrogen on ovarian cancer cells. Some ovarian cancer cells use estrogen to help them grow, so blocking estrogen may help control the cancer. […] Hormone therapy might be a treatment option for some types of slow-growing ovarian cancers. It may also be an option if the cancer comes back after initial treatments. […] Immunotherapy uses the immune system to fight cancer. The body’s disease-fighting immune system may not attack cancer cells because they produce proteins that help them hide from the immune system cells. Immunotherapy works by interfering with that process.

• #57 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  If you’re considering targeted therapy for ovarian cancer, your doctor may test your cancer cells to determine which targeted therapy is most likely to have an effect on your cancer. […] Hormone therapy uses drugs to block the effects of the hormone estrogen on ovarian cancer cells. Some ovarian cancer cells use estrogen to help them grow, so blocking estrogen may help control the cancer. […] Hormone therapy might be a treatment option for some types of slow-growing ovarian cancers. It may also be an option if the cancer comes back after initial treatments. […] Immunotherapy uses the immune system to fight cancer. The body’s disease-fighting immune system may not attack cancer cells because they produce proteins that help them hide from the immune system cells. Immunotherapy works by interfering with that process.

• #58 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  If you’re considering targeted therapy for ovarian cancer, your doctor may test your cancer cells to determine which targeted therapy is most likely to have an effect on your cancer. […] Hormone therapy uses drugs to block the effects of the hormone estrogen on ovarian cancer cells. Some ovarian cancer cells use estrogen to help them grow, so blocking estrogen may help control the cancer. […] Hormone therapy might be a treatment option for some types of slow-growing ovarian cancers. It may also be an option if the cancer comes back after initial treatments. […] Immunotherapy uses the immune system to fight cancer. The body’s disease-fighting immune system may not attack cancer cells because they produce proteins that help them hide from the immune system cells. Immunotherapy works by interfering with that process.

• #59 Ovarian Cancer Treatment Protocols: Treatment Protocols

  https://emedicine.medscape.com/article/2006723-overview

  If recurrence occurs more than 6 months after initial or subsequent complete clinical response to platinum-containing chemotherapy, the patient should be treated with one of the IV platinum-containing combination regimens below. […] If recurrence occurs less than 6 months after initial or subsequent complete clinical response to platinum-containing chemotherapy, the patient should be treated with one of the regimens below. […] PARP inhibitors are FDA approved as maintenance therapy in patients who have had at least a partial platinum response. […] Hormonal therapy may be considered for patients who have asymptomatic recurrence or who require a break from regular chemotherapy if they are not tolerating treatment well. […] Elderly patients may not tolerate chemotherapy as well as younger patients. Comorbid conditions also affect tolerance to chemotherapy and necessitate close monitoring and dose reductions; such conditions may include liver or kidney dysfunction.

• #60 How Cancer Is Treated

  https://www.verywellhealth.com/ovarian-cancer-treatment-2553390

  With a few exceptions, such as blood-related cancers like leukemia, surgery offers the best chance to cure a cancer or at least significantly reduce the chance that it could recur. […] For example, with some ovarian cancers, debulking surgery may reduce the amount of tumor present, allowing chemotherapy to be more effective before the tumor becomes resistant to these drugs. […] Chemotherapy may be used to prolong life. […] Palliative chemotherapy refers to the use of chemotherapy to decrease the symptoms of cancer, but not to cure cancer or extend life. […] Hormone treatments also called endocrine therapy block this stimulating effect of the hormones to stop the growth of a cancer. […] Surgical removal of the ovaries (oophorectomy) may inhibit the production of estrogen.

• #61 How Cancer Is Treated

  https://www.verywellhealth.com/ovarian-cancer-treatment-2553390

  With a few exceptions, such as blood-related cancers like leukemia, surgery offers the best chance to cure a cancer or at least significantly reduce the chance that it could recur. […] For example, with some ovarian cancers, debulking surgery may reduce the amount of tumor present, allowing chemotherapy to be more effective before the tumor becomes resistant to these drugs. […] Chemotherapy may be used to prolong life. […] Palliative chemotherapy refers to the use of chemotherapy to decrease the symptoms of cancer, but not to cure cancer or extend life. […] Hormone treatments also called endocrine therapy block this stimulating effect of the hormones to stop the growth of a cancer. […] Surgical removal of the ovaries (oophorectomy) may inhibit the production of estrogen.

• #62 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  If you’re considering targeted therapy for ovarian cancer, your doctor may test your cancer cells to determine which targeted therapy is most likely to have an effect on your cancer. […] Hormone therapy uses drugs to block the effects of the hormone estrogen on ovarian cancer cells. Some ovarian cancer cells use estrogen to help them grow, so blocking estrogen may help control the cancer. […] Hormone therapy might be a treatment option for some types of slow-growing ovarian cancers. It may also be an option if the cancer comes back after initial treatments. […] Immunotherapy uses the immune system to fight cancer. The body’s disease-fighting immune system may not attack cancer cells because they produce proteins that help them hide from the immune system cells. Immunotherapy works by interfering with that process.

• #63 Treatments for ovarian cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/ovarian/treatment

  If you have ovarian cancer, your healthcare team will create a treatment plan just for you. It will be based on your health and specific information about the cancer. When deciding which treatments to offer for ovarian cancer, your healthcare team will consider: […] Surgery is the primary treatment for all types of ovarian cancer. The type of surgery depends mainly on the type of the tumour and stage of the cancer. […] Chemotherapy may be given after surgery for some types of ovarian cancer. […] Radiation therapy uses high-energy rays or particles to destroy cancer cells. Radiation is rarely used to treat ovarian cancer. […] Hormone therapy is a systemic therapy that slows the growth and spread of ovarian cancer cells by changing hormone levels in the body. […] Some women with ovarian cancer have targeted therapy. It uses drugs to target specific molecules (such as proteins) on cancer cells or inside them. […] Ovarian cancer is sometimes treated with immunotherapy. It helps strengthen the immune system to fight cancer. […] Women with ovarian cancer should talk to their doctor about a follow-up plan that suits their individual situation.

• #64 Ovarian Cancer Treatment – UChicago Medicine

  https://www.uchicagomedicine.org/cancer/types-treatments/ovarian-cancer/treatment

  UChicago Medicine is also actively involved in clinical trials designed to improve current chemotherapy for ovarian cancer. […] Our gynecologic oncologists take this into account for each and every patient and proactively work to address these concerns. […] Radiation therapy is occasionally used for isolated sites of recurrent disease. […] HIPEC is an aggressive, targeted surgical technique that attacks abdominal cancer with fewer side effects than traditional chemotherapy. […] HIPEC helps with fewer side effects than traditional chemotherapy, deeper penetration of the medicine, and greater effectiveness in killing cancer cells than conventional chemotherapy.

• #65 Treating the symptoms of advanced ovarian cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/ovarian-cancer/treatment/treating-symptoms-advanced

  You might have surgery for advanced cancer. Your specialist surgeon (gynaecological oncologist) will check where the cancer is in your tummy (abdomen) and remove as much of it as possible. […] Targeted cancer drugs can help the body to control the growth of cancer cells. […] Radiotherapy uses high energy rays to destroy cancer cells. Occasionally doctors suggest radiotherapy for advanced ovarian cancer. Radiotherapy can shrink cancers and reduce symptoms. […] The treatment you have for ovarian cancer, such as chemotherapy, can help to reduce the build up of fluid. […] To relieve the symptoms, an operation can sometimes unblock the bowel. The surgeon removes enough of the cancer to unblock the bowel. […] If surgery is not an option, doctors might use: […] Your doctor may suggest putting in a tube to bypass the blockage and drain urine from the kidney. […] The main treatments for ovarian cancer are surgery and chemotherapy. Your treatment depends on several factors including your cancer stage and grade.

• #66 Ovarian Cancer: Treatment Choices

  https://healthlibrary.brighamandwomens.org/RelatedItems/34,17195-1

  This treatment uses medicines to slow the growth of or kill the cancer. It also reduces the chance of it coming back. Chemo is advised in most cases, even for early-stage disease. It may be given by IV (intravenously). Or it may be put right into your belly (abdomen). This is called IP (intraperitoneal) chemo. […] Chemo may be given before, during, or after surgery. It might be the only treatment used if surgery can’t be done. […] This treatment uses high-energy X-rays to kill cancer cells. Its rarely used to treat ovarian cancer. But it may be used to ease symptoms caused by ovarian cancer that has spread to the bone or brain. External beam radiation therapy is most often used. This type of radiation comes from a machine that aims strong rays of energy at the tumor from outside of the body.

• #67 Ovarian Cancer

  https://medschool.cuanschutz.edu/colorado-cancer-center/for-patients-families/cancers-we-treat/ovarian-cancer

  Ovarian cancer can go undetected until it starts to spread beyond the ovary and further into the abdomen and pelvis. […] Early-stage ovarian cancer describes disease that is confined to the ovary and is typically easier to treat and often has a better prognosis. […] The five-year survival rate for ovarian cancer varies by the specific type of ovarian cancer and the stage at which it is discovered. […] The treatment for ovarian cancer is customized to each patient and depends on the size and location of the tumor(s), the stage at which the patient is diagnosed, and the patient’s general health. […] Treatments for ovarian cancer include surgery, radiation therapy, chemotherapy, hormone therapy, and targeted drug therapy. […] Surgery is one of the primary treatments for ovarian cancer.

• #68 Treatment options for ovarian cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/ovarian-cancer/treatment/treatment-decisions

  A team of health professionals will discuss the best treatment for you. This depends on factors such as your cancer stage and grade. You might have one or more treatments. The most common treatments are surgery and chemotherapy. […] The main treatments for ovarian cancer are surgery and chemotherapy. Some women with ovarian cancer have: targeted drug treatment, hormone treatment, radiotherapy. […] Most women with ovarian cancer need surgery. The amount and type of surgery you have depends on your stage and type of cancer. […] Chemotherapy uses anti cancer (cytotoxic) drugs to destroy cancer cells. […] You may have treatment with a targeted cancer drug. This will depend on your situation. […] If your cancer is hormone sensitive you might have hormone therapy. This is not a common treatment for ovarian cancer.

• #69 Ovarian Cancer Staging – Ovarian Cancer Research Alliance

  https://ocrahope.org/for-patients/gynecologic-cancers/ovarian-cancer/ovarian-cancer-staging/

  Stage 1 Ovarian Cancer Treatment Ovarian cancer patients generally undergo a total abdominal hysterectomy, salpingo-oophorectomy (removal of both ovaries and fallopian tubes), omentectomy (removal of the omentum), and lymph node biopsies to check for disease spread. If no cancer is found outside the ovary, the cancer is confirmed as Stage 1. […] Stage 2 Ovarian Cancer Treatment Stage 2 ovarian cancer treatment typically includes a hysterectomy, bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes), tumor debulking, and lymph node and tissue sampling to check for cancer spread. Most patients receive chemotherapy after surgery. […] Stage 3 Ovarian Cancer Treatment Treatment for Stage 3 ovarian cancer includes surgery and chemotherapy. At surgery, a hysterectomy and bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes) is performed, along with resection of as much of the tumor as possible. In addition, lymph nodes and other tissues in the pelvis and abdomen that are suspected of harboring cancer may be removed. Depending on the distribution of disease on imaging studies or other pre-operative assessments, some people may have chemotherapy prior to surgery. This often results in tumor shrinkage, which may enable a less aggressive surgery to be performed. Other people may have surgery first, followed by chemotherapy. […] Stage 4 Ovarian Cancer Treatment Treatment for Stage 4 ovarian cancer will usually consist of surgery to remove as much of the tumor as possible, in combination with chemotherapy.

• #70 Ovarian Cancer Staging – Ovarian Cancer Research Alliance

  https://ocrahope.org/for-patients/gynecologic-cancers/ovarian-cancer/ovarian-cancer-staging/

  Stage 1 Ovarian Cancer Treatment Ovarian cancer patients generally undergo a total abdominal hysterectomy, salpingo-oophorectomy (removal of both ovaries and fallopian tubes), omentectomy (removal of the omentum), and lymph node biopsies to check for disease spread. If no cancer is found outside the ovary, the cancer is confirmed as Stage 1. […] Stage 2 Ovarian Cancer Treatment Stage 2 ovarian cancer treatment typically includes a hysterectomy, bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes), tumor debulking, and lymph node and tissue sampling to check for cancer spread. Most patients receive chemotherapy after surgery. […] Stage 3 Ovarian Cancer Treatment Treatment for Stage 3 ovarian cancer includes surgery and chemotherapy. At surgery, a hysterectomy and bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes) is performed, along with resection of as much of the tumor as possible. In addition, lymph nodes and other tissues in the pelvis and abdomen that are suspected of harboring cancer may be removed. Depending on the distribution of disease on imaging studies or other pre-operative assessments, some people may have chemotherapy prior to surgery. This often results in tumor shrinkage, which may enable a less aggressive surgery to be performed. Other people may have surgery first, followed by chemotherapy. […] Stage 4 Ovarian Cancer Treatment Treatment for Stage 4 ovarian cancer will usually consist of surgery to remove as much of the tumor as possible, in combination with chemotherapy.

• #71 Treatment options for ovarian cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/ovarian-cancer/treatment/treatment-decisions

  A team of health professionals will discuss the best treatment for you. This depends on factors such as your cancer stage and grade. You might have one or more treatments. The most common treatments are surgery and chemotherapy. […] The main treatments for ovarian cancer are surgery and chemotherapy. Some women with ovarian cancer have: targeted drug treatment, hormone treatment, radiotherapy. […] Most women with ovarian cancer need surgery. The amount and type of surgery you have depends on your stage and type of cancer. […] Chemotherapy uses anti cancer (cytotoxic) drugs to destroy cancer cells. […] You may have treatment with a targeted cancer drug. This will depend on your situation. […] If your cancer is hormone sensitive you might have hormone therapy. This is not a common treatment for ovarian cancer.

• #72 Ovarian Cancer Treatment Protocols: Treatment Protocols

  https://emedicine.medscape.com/article/2006723-overview

  Treatment protocols for ovarian cancer are provided below, including the following: […] Surgery is the initial modality of treatment for stage I-IVA epithelial ovarian cancer. However, only a small percentage of women with epithelial ovarian cancer can be treated with surgery alone. […] High-risk features such as stage IC, higher grade, or clear-cell histology should prompt consideration of adjuvant chemotherapy. […] Women with any stage of epithelial ovarian cancer should be considered for clinical trials if available. […] Consider chemotherapy for stages 1A and 1B grades 2 and 3, and stage 1C. Chemotherapy is usually given after surgery. […] All patients with stage II or higher cancer should be considered for front-line chemotherapy based on burden of disease and ability to achieve optimal primary resection.

• #73 Ovarian Cancer Staging – Ovarian Cancer Research Alliance

  https://ocrahope.org/for-patients/gynecologic-cancers/ovarian-cancer/ovarian-cancer-staging/

  Stage 1 Ovarian Cancer Treatment Ovarian cancer patients generally undergo a total abdominal hysterectomy, salpingo-oophorectomy (removal of both ovaries and fallopian tubes), omentectomy (removal of the omentum), and lymph node biopsies to check for disease spread. If no cancer is found outside the ovary, the cancer is confirmed as Stage 1. […] Stage 2 Ovarian Cancer Treatment Stage 2 ovarian cancer treatment typically includes a hysterectomy, bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes), tumor debulking, and lymph node and tissue sampling to check for cancer spread. Most patients receive chemotherapy after surgery. […] Stage 3 Ovarian Cancer Treatment Treatment for Stage 3 ovarian cancer includes surgery and chemotherapy. At surgery, a hysterectomy and bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes) is performed, along with resection of as much of the tumor as possible. In addition, lymph nodes and other tissues in the pelvis and abdomen that are suspected of harboring cancer may be removed. Depending on the distribution of disease on imaging studies or other pre-operative assessments, some people may have chemotherapy prior to surgery. This often results in tumor shrinkage, which may enable a less aggressive surgery to be performed. Other people may have surgery first, followed by chemotherapy. […] Stage 4 Ovarian Cancer Treatment Treatment for Stage 4 ovarian cancer will usually consist of surgery to remove as much of the tumor as possible, in combination with chemotherapy.

• #74 Ovarian Cancer Staging – Ovarian Cancer Research Alliance

  https://ocrahope.org/for-patients/gynecologic-cancers/ovarian-cancer/ovarian-cancer-staging/

  Stage 1 Ovarian Cancer Treatment Ovarian cancer patients generally undergo a total abdominal hysterectomy, salpingo-oophorectomy (removal of both ovaries and fallopian tubes), omentectomy (removal of the omentum), and lymph node biopsies to check for disease spread. If no cancer is found outside the ovary, the cancer is confirmed as Stage 1. […] Stage 2 Ovarian Cancer Treatment Stage 2 ovarian cancer treatment typically includes a hysterectomy, bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes), tumor debulking, and lymph node and tissue sampling to check for cancer spread. Most patients receive chemotherapy after surgery. […] Stage 3 Ovarian Cancer Treatment Treatment for Stage 3 ovarian cancer includes surgery and chemotherapy. At surgery, a hysterectomy and bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes) is performed, along with resection of as much of the tumor as possible. In addition, lymph nodes and other tissues in the pelvis and abdomen that are suspected of harboring cancer may be removed. Depending on the distribution of disease on imaging studies or other pre-operative assessments, some people may have chemotherapy prior to surgery. This often results in tumor shrinkage, which may enable a less aggressive surgery to be performed. Other people may have surgery first, followed by chemotherapy. […] Stage 4 Ovarian Cancer Treatment Treatment for Stage 4 ovarian cancer will usually consist of surgery to remove as much of the tumor as possible, in combination with chemotherapy.

• #75 Treatments for epithelial ovarian cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/ovarian/treatment/epithelial-ovarian-cancer

  The following are treatment options for the stages of epithelial ovarian cancer. Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan. […] Surgery is the first treatment given for stage 1 epithelial ovarian cancer. It is done to remove the cancer and to see if there is any spread outside of the ovaries. […] Chemotherapy may be given after surgery for stage 1 epithelial ovarian cancer. […] A combination of a platinum drug, such as cisplatin or carboplatin, and a taxane drug, such as paclitaxel or docetaxel, is used. […] Stage 1C treatment is surgery followed by chemotherapy. […] Surgery is the first treatment given for stage 2 epithelial ovarian cancer. […] Chemotherapy is usually given following surgery. […] Surgery is the first treatment given for stage 3 epithelial ovarian cancer.

• #76 Ovarian Cancer Staging – Ovarian Cancer Research Alliance

  https://ocrahope.org/for-patients/gynecologic-cancers/ovarian-cancer/ovarian-cancer-staging/

  Stage 1 Ovarian Cancer Treatment Ovarian cancer patients generally undergo a total abdominal hysterectomy, salpingo-oophorectomy (removal of both ovaries and fallopian tubes), omentectomy (removal of the omentum), and lymph node biopsies to check for disease spread. If no cancer is found outside the ovary, the cancer is confirmed as Stage 1. […] Stage 2 Ovarian Cancer Treatment Stage 2 ovarian cancer treatment typically includes a hysterectomy, bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes), tumor debulking, and lymph node and tissue sampling to check for cancer spread. Most patients receive chemotherapy after surgery. […] Stage 3 Ovarian Cancer Treatment Treatment for Stage 3 ovarian cancer includes surgery and chemotherapy. At surgery, a hysterectomy and bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes) is performed, along with resection of as much of the tumor as possible. In addition, lymph nodes and other tissues in the pelvis and abdomen that are suspected of harboring cancer may be removed. Depending on the distribution of disease on imaging studies or other pre-operative assessments, some people may have chemotherapy prior to surgery. This often results in tumor shrinkage, which may enable a less aggressive surgery to be performed. Other people may have surgery first, followed by chemotherapy. […] Stage 4 Ovarian Cancer Treatment Treatment for Stage 4 ovarian cancer will usually consist of surgery to remove as much of the tumor as possible, in combination with chemotherapy.

• #77 Ovarian Cancer Staging – Ovarian Cancer Research Alliance

  https://ocrahope.org/for-patients/gynecologic-cancers/ovarian-cancer/ovarian-cancer-staging/

  Stage 1 Ovarian Cancer Treatment Ovarian cancer patients generally undergo a total abdominal hysterectomy, salpingo-oophorectomy (removal of both ovaries and fallopian tubes), omentectomy (removal of the omentum), and lymph node biopsies to check for disease spread. If no cancer is found outside the ovary, the cancer is confirmed as Stage 1. […] Stage 2 Ovarian Cancer Treatment Stage 2 ovarian cancer treatment typically includes a hysterectomy, bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes), tumor debulking, and lymph node and tissue sampling to check for cancer spread. Most patients receive chemotherapy after surgery. […] Stage 3 Ovarian Cancer Treatment Treatment for Stage 3 ovarian cancer includes surgery and chemotherapy. At surgery, a hysterectomy and bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes) is performed, along with resection of as much of the tumor as possible. In addition, lymph nodes and other tissues in the pelvis and abdomen that are suspected of harboring cancer may be removed. Depending on the distribution of disease on imaging studies or other pre-operative assessments, some people may have chemotherapy prior to surgery. This often results in tumor shrinkage, which may enable a less aggressive surgery to be performed. Other people may have surgery first, followed by chemotherapy. […] Stage 4 Ovarian Cancer Treatment Treatment for Stage 4 ovarian cancer will usually consist of surgery to remove as much of the tumor as possible, in combination with chemotherapy.

• #78 Ovarian Cancer Staging – Ovarian Cancer Research Alliance

  https://ocrahope.org/for-patients/gynecologic-cancers/ovarian-cancer/ovarian-cancer-staging/

  Stage 1 Ovarian Cancer Treatment Ovarian cancer patients generally undergo a total abdominal hysterectomy, salpingo-oophorectomy (removal of both ovaries and fallopian tubes), omentectomy (removal of the omentum), and lymph node biopsies to check for disease spread. If no cancer is found outside the ovary, the cancer is confirmed as Stage 1. […] Stage 2 Ovarian Cancer Treatment Stage 2 ovarian cancer treatment typically includes a hysterectomy, bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes), tumor debulking, and lymph node and tissue sampling to check for cancer spread. Most patients receive chemotherapy after surgery. […] Stage 3 Ovarian Cancer Treatment Treatment for Stage 3 ovarian cancer includes surgery and chemotherapy. At surgery, a hysterectomy and bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes) is performed, along with resection of as much of the tumor as possible. In addition, lymph nodes and other tissues in the pelvis and abdomen that are suspected of harboring cancer may be removed. Depending on the distribution of disease on imaging studies or other pre-operative assessments, some people may have chemotherapy prior to surgery. This often results in tumor shrinkage, which may enable a less aggressive surgery to be performed. Other people may have surgery first, followed by chemotherapy. […] Stage 4 Ovarian Cancer Treatment Treatment for Stage 4 ovarian cancer will usually consist of surgery to remove as much of the tumor as possible, in combination with chemotherapy.

• #79 Treatments for epithelial ovarian cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/ovarian/treatment/epithelial-ovarian-cancer

  Chemotherapy is given after surgery with carboplatin or cisplatin along with paclitaxel or docetaxel. […] Stage 4 epithelial ovarian cancer is often treated with surgery and chemotherapy. […] Chemotherapy for stage 4 epithelial ovarian cancer is often carboplatin or cisplatin with paclitaxel or docetaxel. […] Surgery may be offered for recurrent or persistent epithelial ovarian cancer. […] Chemotherapy with a combination of drugs is usually used to treat recurrent or persistent epithelial ovarian cancer. […] Targeted therapy may be used to treat advanced epithelial ovarian cancer. […] Hormone therapy may be given in addition to chemotherapy to treat advanced epithelial ovarian cancer. […] Radiation therapy is sometimes given to treat advanced epithelial ovarian cancer.

• #80 Treatment options for ovarian cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/ovarian-cancer/treatment/treatment-decisions

  Radiotherapy uses high energy x-rays to destroy ovarian cancer cells. Doctors don’t often use radiotherapy to treat ovarian cancer. […] Surgery is the main treatment for stage 1 ovarian cancer. […] Surgery and chemotherapy are the main treatments for stage 2, 3 and 4 cancers. […] You might have chemotherapy on its own or combined with other treatments. […] Some women with stage 3 or 4 ovarian cancer have also targeted cancer drugs. You might have this with chemotherapy, or on its own after chemotherapy. […] Your doctor may ask if youd like to take part in a clinical trial. […] Doctors and researchers do trials to improve treatment, reduce the side effects of treatment, develop new treatments.

• #81 Ovarian cancer treatment: Stages 1, 2, 3, and 4

  https://www.medicalnewstoday.com/articles/ovarian-cancer-treatment

  Immunotherapy, which involves using the bodys own immune system against cancer, may also be an option in some cases. […] The first treatment for stage 1 ovarian cancer is surgery to remove the tumor. […] A person may need surgery for staging and debulking, which usually includes a complete hysterectomy, a BSO, and chemotherapy. […] Doctors often treat stage 3 ovarian cancer in a similar way to stage 2. […] A doctor will determine the treatment for stage 4 ovarian cancer depending on the persons needs. Treatment typically begins with chemotherapy, to shrink the cancer, and then surgery. […] The most common treatment that doctors use for ovarian cancer is surgery. […] Depending on the severity of the cancer a person has, a doctor may use additional treatment options, including, most commonly, chemotherapy.

• #82 Treatments for epithelial ovarian cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/ovarian/treatment/epithelial-ovarian-cancer

  Chemotherapy is given after surgery with carboplatin or cisplatin along with paclitaxel or docetaxel. […] Stage 4 epithelial ovarian cancer is often treated with surgery and chemotherapy. […] Chemotherapy for stage 4 epithelial ovarian cancer is often carboplatin or cisplatin with paclitaxel or docetaxel. […] Surgery may be offered for recurrent or persistent epithelial ovarian cancer. […] Chemotherapy with a combination of drugs is usually used to treat recurrent or persistent epithelial ovarian cancer. […] Targeted therapy may be used to treat advanced epithelial ovarian cancer. […] Hormone therapy may be given in addition to chemotherapy to treat advanced epithelial ovarian cancer. […] Radiation therapy is sometimes given to treat advanced epithelial ovarian cancer.

• #83

  https://www.nhs.uk/conditions/ovarian-cancer/treatment/

  They may be an option for some types of advanced ovarian cancer. […] Hormone treatments can block the production of oestrogen to stop some cancers from growing. […] Treatment for ovarian cancer in younger women can affect periods and fertility, which may mean you may not be able to have a baby. […] If you have advanced ovarian cancer, it might be very hard to treat. It may not be possible to cure the cancer. […] If this is the case, the aim of your treatment will be to limit the cancer and its symptoms, and help you live longer.

• #84

  https://www.nhs.uk/conditions/ovarian-cancer/treatment/

  They may be an option for some types of advanced ovarian cancer. […] Hormone treatments can block the production of oestrogen to stop some cancers from growing. […] Treatment for ovarian cancer in younger women can affect periods and fertility, which may mean you may not be able to have a baby. […] If you have advanced ovarian cancer, it might be very hard to treat. It may not be possible to cure the cancer. […] If this is the case, the aim of your treatment will be to limit the cancer and its symptoms, and help you live longer.

• #85 Treatment for Ovarian Cancer | Fred Hutchinson Cancer Center

  https://www.fredhutch.org/en/diseases/ovarian-cancer/treatment.html

  Chemotherapy is more effective if as much of the cancer as possible is removed and your doctors may recommend chemotherapy following your surgery to destroy any cancer cells remaining. […] Because of the difficulty of diagnosing ovarian cancer early, most people have stage III or IV disease meaning the cancer has spread beyond the ovaries by the time they are diagnosed. […] Even so, the majority (70 percent or better) of the women we treat for ovarian cancer can expect a complete response to their initial treatment. […] If you have recurrent ovarian cancer, Fred Hutch can offer you new medical procedures and treatments, as well as access to clinical trials, that your community doctor may not know about. […] There are a number of new drugs that are effective against recurrent ovarian cancer, and one of these drugs may put you back in remission.

• #86 Ovarian Cancer Treatment Protocols: Treatment Protocols

  https://emedicine.medscape.com/article/2006723-overview

  The addition of bevacizumab to front-line therapy is still controversial with benefits of around 4 months PFS but no improvement in OS. […] Consolidation is treatment given after completion of front-line therapy with a complete clinical or pathologic response. […] While used as standard treatment in other malignancies, such as appendiceal cancer, hyperthermic intraperitoneal chemotherapy (HIPEC) has been less adopted in the treatment of ovarian cancer, given logistical considerations in administration and concern for postoperative complications. […] Stages III and IV disease have a high rate of recurrence. These patients should be considered for clinical trials. Treatment is usually with chemotherapy; the regimen choice depends on the time elapsed since previous complete response to platinum-containing chemotherapy.

• #87 Patient education: Treatment of ovarian cancer (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/treatment-of-ovarian-cancer-beyond-the-basics

  If the initial treatment with chemotherapy worked, and the response lasted for at least six months, a female is considered to have „platinum-sensitive” cancer. […] If patients have persistent or nonresponsive ovarian cancer despite first-line therapy with paclitaxel and a platinum agent, or if they relapse within six months of completing such therapy, they are considered to have „platinum-resistant” cancer. […] Progress in treating cancer requires that better treatments be identified through clinical trials.

• #88 Ovarian Cancer Treatment Protocols: Treatment Protocols

  https://emedicine.medscape.com/article/2006723-overview

  If recurrence occurs more than 6 months after initial or subsequent complete clinical response to platinum-containing chemotherapy, the patient should be treated with one of the IV platinum-containing combination regimens below. […] If recurrence occurs less than 6 months after initial or subsequent complete clinical response to platinum-containing chemotherapy, the patient should be treated with one of the regimens below. […] PARP inhibitors are FDA approved as maintenance therapy in patients who have had at least a partial platinum response. […] Hormonal therapy may be considered for patients who have asymptomatic recurrence or who require a break from regular chemotherapy if they are not tolerating treatment well. […] Elderly patients may not tolerate chemotherapy as well as younger patients. Comorbid conditions also affect tolerance to chemotherapy and necessitate close monitoring and dose reductions; such conditions may include liver or kidney dysfunction.

• #89 Treatments for epithelial ovarian cancer | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/ovarian/treatment/epithelial-ovarian-cancer

  Chemotherapy is given after surgery with carboplatin or cisplatin along with paclitaxel or docetaxel. […] Stage 4 epithelial ovarian cancer is often treated with surgery and chemotherapy. […] Chemotherapy for stage 4 epithelial ovarian cancer is often carboplatin or cisplatin with paclitaxel or docetaxel. […] Surgery may be offered for recurrent or persistent epithelial ovarian cancer. […] Chemotherapy with a combination of drugs is usually used to treat recurrent or persistent epithelial ovarian cancer. […] Targeted therapy may be used to treat advanced epithelial ovarian cancer. […] Hormone therapy may be given in addition to chemotherapy to treat advanced epithelial ovarian cancer. […] Radiation therapy is sometimes given to treat advanced epithelial ovarian cancer.

• #90 Patient education: Treatment of ovarian cancer (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/treatment-of-ovarian-cancer-beyond-the-basics

  If the initial treatment with chemotherapy worked, and the response lasted for at least six months, a female is considered to have „platinum-sensitive” cancer. […] If patients have persistent or nonresponsive ovarian cancer despite first-line therapy with paclitaxel and a platinum agent, or if they relapse within six months of completing such therapy, they are considered to have „platinum-resistant” cancer. […] Progress in treating cancer requires that better treatments be identified through clinical trials.

• #91 Ovarian Cancer Treatment Protocols: Treatment Protocols

  https://emedicine.medscape.com/article/2006723-overview

  If recurrence occurs more than 6 months after initial or subsequent complete clinical response to platinum-containing chemotherapy, the patient should be treated with one of the IV platinum-containing combination regimens below. […] If recurrence occurs less than 6 months after initial or subsequent complete clinical response to platinum-containing chemotherapy, the patient should be treated with one of the regimens below. […] PARP inhibitors are FDA approved as maintenance therapy in patients who have had at least a partial platinum response. […] Hormonal therapy may be considered for patients who have asymptomatic recurrence or who require a break from regular chemotherapy if they are not tolerating treatment well. […] Elderly patients may not tolerate chemotherapy as well as younger patients. Comorbid conditions also affect tolerance to chemotherapy and necessitate close monitoring and dose reductions; such conditions may include liver or kidney dysfunction.

• #92 Targeted Drug Therapy for Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating/targeted-therapy.html

  Olaparib can be used as maintenance treatment for advanced ovarian cancer that has gotten smaller in response to first treatment with chemotherapy containing cisplatin or carboplatin. […] Niraparib (Zejula) may be used in some situations to treat ovarian cancer. […] Rucaparib (Rubraca) can be used in women with or without a BRCA mutation, as maintenance treatment for advanced ovarian cancer that has come back after treatment, and then has shrunk in response to chemotherapy containing cisplatin or carboplatin. […] These drugs have been shown to help shrink or slow the growth of some advanced ovarian cancers for a time. So far, though, it’s not clear if they can help women live longer. […] Mirvetuximab soravtansine (Elahere) is an antibody-drug conjugate (ADC), which is a lab-made antibody linked to a chemotherapy drug. This drug can be used to treat epithelial ovarian cancer that tests positive for FR-alpha and that is no longer responding to platinum chemotherapy drugs such as cisplatin or carboplatin. […] Larotrectinib (Vitrakvi) and entrectinib (Rozlytrek) are targeted drugs that stop the proteins made by the abnormal NTRK genes. These drugs can be used in people with advanced ovarian cancer whose tumor has an NTRK gene change and is still growing despite other treatments.

• #93 Treatment for Ovarian Cancer | Fred Hutchinson Cancer Center

  https://www.fredhutch.org/en/diseases/ovarian-cancer/treatment.html

  Chemotherapy is more effective if as much of the cancer as possible is removed and your doctors may recommend chemotherapy following your surgery to destroy any cancer cells remaining. […] Because of the difficulty of diagnosing ovarian cancer early, most people have stage III or IV disease meaning the cancer has spread beyond the ovaries by the time they are diagnosed. […] Even so, the majority (70 percent or better) of the women we treat for ovarian cancer can expect a complete response to their initial treatment. […] If you have recurrent ovarian cancer, Fred Hutch can offer you new medical procedures and treatments, as well as access to clinical trials, that your community doctor may not know about. […] There are a number of new drugs that are effective against recurrent ovarian cancer, and one of these drugs may put you back in remission.

• #94 Ovarian cancer: New treatments and research – Mayo Clinic Comprehensive Cancer Center Blog

  https://cancerblog.mayoclinic.org/2024/05/01/ovarian-cancer-new-treatments-and-research/

  Three cancers ovarian epithelial cancer, fallopian tube cancer and primary peritoneal cancer are commonly called ovarian cancer. They arise from the same kind of tissue and are treated similarly. […] Dr. Weroha says new treatments are helping more people survive ovarian cancer of all types, and researchers are studying new treatments and screening methods in clinical trials. If you’ve been diagnosed with ovarian cancer, he wants you to know there is hope. Here’s why: […] Surgery and chemotherapy are no longer the only options for ovarian cancer treatment. Targeted therapies use drugs to target and attack cancer cells. These include monoclonal antibodies and poly (ADP-ribose) polymerase, or PARP, inhibitors. […] Monoclonal antibodies are molecules engineered in the laboratory to find and attach to specific proteins associated with cancer cells. Bevacizumab is a monoclonal antibody used with chemotherapy to treat ovarian cancer recurrence by preventing the growth of new blood vessels that tumors need to grow.

• #95 Treatment of Ovarian Cancer | Ovarian Cancer | CDC

  https://www.cdc.gov/ovarian-cancer/treatment/index.html

  Talk to your cancer doctor about the treatment options available for your type and stage of cancer. Your doctor can explain the risks and benefits of each treatment and their side effects. […] Sometimes people get an opinion from more than one cancer doctor. This is called a „second opinion.” Getting a second opinion may help you choose the treatment that is right for you. […] Clinical trials use new treatment options to see if they are safe and effective. If you have cancer, you may want to take part. […] Complementary and alternative medicine are medicines and health practices that are not standard cancer treatments. Complementary medicine is used in addition to standard treatments. Alternative medicine is used instead of standard treatments. […] Talk to your doctor about the risks and benefits before you start any kind of complementary or alternative medicine.

• #96 Treatment options for ovarian cancer | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/ovarian-cancer/treatment/treatment-decisions

  Radiotherapy uses high energy x-rays to destroy ovarian cancer cells. Doctors don’t often use radiotherapy to treat ovarian cancer. […] Surgery is the main treatment for stage 1 ovarian cancer. […] Surgery and chemotherapy are the main treatments for stage 2, 3 and 4 cancers. […] You might have chemotherapy on its own or combined with other treatments. […] Some women with stage 3 or 4 ovarian cancer have also targeted cancer drugs. You might have this with chemotherapy, or on its own after chemotherapy. […] Your doctor may ask if youd like to take part in a clinical trial. […] Doctors and researchers do trials to improve treatment, reduce the side effects of treatment, develop new treatments.

• #97 Ovarian cancer: New treatments and research – Mayo Clinic Comprehensive Cancer Center Blog

  https://cancerblog.mayoclinic.org/2024/05/01/ovarian-cancer-new-treatments-and-research/

  Researchers are combining bevacizumab with new drugs to improve outcomes. One example is a monoclonal antibody recently approved by the Food and Drug Administration (FDA) called mirvetuximab soravtansine for people with ovarian cancer recurrence. […] PARP inhibitors are drugs that block DNA repair, which may cause cancer cells to die. Olaparib is an example of a PARP inhibitor used to prevent recurrence in people with ovarian cancer whose tumors have BRCA1 or BRCA2 gene mutations. Research has shown that olaparib can significantly improve survival without recurrence in people with this diagnosis. […] Matthew Block, M.D., Ph.D., a Mayo Clinic medical oncologist, and Keith Knutson, Ph.D., a Mayo Clinic researcher, are developing a vaccine to prevent ovarian cancer tumors from returning in people with advanced ovarian cancer whose tumors have recurred after surgery and chemotherapy.

• #98 UCSF Ovarian Cancer Clinical Trials for 2025 — San Francisco Bay Area

  https://clinicaltrials.ucsf.edu/ovarian-cancer

  Durvalumab Treatment in Combination With Chemotherapy and Bevacizumab, Followed by Maintenance Durvalumab, Bevacizumab and Olaparib Treatment in Advanced Ovarian Cancer Patients. This is a Phase III randomised, double-blind, multi-centre study to evaluate the efficacy and safety of durvalumab in combination with standard of care platinum based chemotherapy and bevacizumab followed by maintenance durvalumab and bevacizumab or durvalumab, bevacizumab and olaparib in patients with newly diagnosed advanced ovarian cancer. […] […] Nivolumab With or Without Ipilimumab in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer. This randomized phase II trial studies how well nivolumab works with or without ipilimumab in treating patients with epithelial ovarian, primary peritoneal, or fallopian tube cancer that has not responded after prior treatment (persistent) or has come back (recurrent). Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. […]

• #99 UCSF Ovarian Cancer Clinical Trials for 2025 — San Francisco Bay Area

  https://clinicaltrials.ucsf.edu/ovarian-cancer

  Niraparib (GSK3985771) Maintenance Treatment in Participants With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy. This study aims to assess efficacy of Niraparib (GSK3985771) as maintenance treatment in participants with Stage III or IV ovarian cancer. Participants must have completed front-line platinum based regimen with complete response (CR) or partial response (PR). Data collection for Secondary Outcome measures is ongoing and the approximate duration of the study will be 7 years. […] […] Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer. This randomized phase III trial studies carboplatin, paclitaxel and gemcitabine hydrochloride when given together with or without bevacizumab after surgery to see how well it works in treating patients with ovarian, epithelial, primary peritoneal, or fallopian tube cancer that has come back. Drugs used in chemotherapy, such as carboplatin, paclitaxel and gemcitabine hydrochloride work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as bevacizumab, may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. It is not yet known whether combination chemotherapy is more effective when given with or without bevacizumab after surgery in treating patients with ovarian, epithelial, primary peritoneal, or fallopian tube cancer. […]

• #100 UCSF Ovarian Cancer Clinical Trials for 2025 — San Francisco Bay Area

  https://clinicaltrials.ucsf.edu/ovarian-cancer

  Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer. This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary peritoneal cancer that has returned (recurrent) after receiving chemotherapy with drugs that contain platinum (platinum-resistant) or continued to grow while being treated with platinum-based chemotherapy drugs (platinum-refractory). Cediranib maleate and olaparib may stop the growth of tumor cells by blocking enzymes needed for cell growth. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving cediranib maleate and olaparib together may cause more damage to cancer cells when compared to either drug alone or standard chemotherapy. […]

• #101 Promising new drugs and therapeutic approaches for treatment of ovarian cancer—targeting the hallmarks of cancer | BMC Medicine | Full Text

  https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03826-w

  First-line therapy for OC includes surgery followed by a chemotherapy combining platinum- and taxane-based treatment. For a long time, this scheme did not undergo major changes, until bevacizumab and PARPi were supplemented for maintenance therapy. According to the SOLO1 study, olaparib was introduced as maintenance treatment of BRCA mutated (BRCAm) OC. Niraparib is further approved as first line maintenance therapy for BRCA-wild type (BRCAwt) and homologous recombination proficient (HRP) patients. Treatment of recurrent OC (ROC) depends on platinum-responsiveness and includes combinational and single therapies with gemcitabine, liposomal doxorubicin, or topotecan. In ROC, PARPi are approved regardless of mutational status. Interestingly a newly developed ADC, MIRV, is approved on folate receptor alpha (FR) overexpressing platinum resistant OC.

• #102 Promising new drugs and therapeutic approaches for treatment of ovarian cancer—targeting the hallmarks of cancer | BMC Medicine | Full Text

  https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-024-03826-w

  PARPi are highly efficient in OC. Among others, PARPi inhibit repair of DNA single-strand breaks and thereby cause accumulation of DNA double-strand breaks. Deficiency of high-quality HR and concurrent inhibition of alternative end joining (alt-EJ) by PARPi, as well as dependency on more error-prone non-homologous end joining (NHEJ) to repair DSBs, leads to accumulation of mutations, unregulated cell division, and apoptosis. […] Thus, today PARPi are considered as first-line standard of care maintenance therapy of OC after response to platinum-based therapy. Based on several phase III studies, investigating olaparib, niraparib, and rucaparib in first-line setting, including SOLO-1, PRIMA, and ATHENA trial which have been reviewed in detail elsewhere, olaparib is approved for first-line maintenance treatment of advanced OC with BRCAm; niraparib is approved regardless of HRD status.

• #103 New drug combination offers hope to women with rare treatment-resistant ovarian cancer

  https://www.icr.ac.uk/about-us/icr-news/detail/new-drug-combination-offers-hope-to-women-with-rare-treatment-resistant-ovarian-cancer

  A combination of two drugs which can block the growth of cancer cells has shown promising results in women with a form of ovarian cancer that rarely responds to chemotherapy or hormone therapy. […] The findings showed that in 115 participants with low-grade serous ovarian cancer, 31 per cent saw their tumours shrink or stop growing when taking a combination of avutometinib and defactinib. This is in comparison to a 0-10 per cent response rate to chemo or hormone therapies in patients with the rare ovarian cancer. Both drugs are designed to block signals that encourage cancer cells to grow. […] The combination of avutometinib and defactinib promises a new standard of care for people with recurrent low-grade serous ovarian cancer. […] However, clinicians are hopeful that this new drug combination will change practice globally for cases of low-grade serous ovarian cancer and most importantly improve outcomes for patients with limited treatment options. […] Overall, nearly half (46 per cent) of patients saw their tumours shrink significantly in response to the treatment.

• #104 New drug combination offers hope to women with rare treatment-resistant ovarian cancer

  https://www.icr.ac.uk/about-us/icr-news/detail/new-drug-combination-offers-hope-to-women-with-rare-treatment-resistant-ovarian-cancer

  A combination of two drugs which can block the growth of cancer cells has shown promising results in women with a form of ovarian cancer that rarely responds to chemotherapy or hormone therapy. […] The findings showed that in 115 participants with low-grade serous ovarian cancer, 31 per cent saw their tumours shrink or stop growing when taking a combination of avutometinib and defactinib. This is in comparison to a 0-10 per cent response rate to chemo or hormone therapies in patients with the rare ovarian cancer. Both drugs are designed to block signals that encourage cancer cells to grow. […] The combination of avutometinib and defactinib promises a new standard of care for people with recurrent low-grade serous ovarian cancer. […] However, clinicians are hopeful that this new drug combination will change practice globally for cases of low-grade serous ovarian cancer and most importantly improve outcomes for patients with limited treatment options. […] Overall, nearly half (46 per cent) of patients saw their tumours shrink significantly in response to the treatment.

• #105 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Immunotherapy might be an option for treating ovarian cancer in certain situations. […] Palliative care is specialized medical care that focuses on providing relief from pain and other symptoms of a serious illness. Palliative care specialists work with you, your family and your other doctors to provide an extra layer of support that complements your ongoing care. Palliative care can be used while undergoing other aggressive treatments, such as surgery and chemotherapy. […] When palliative care is used along with all of the other appropriate treatments, people with cancer may feel better and live longer.

• #106 Ovarian cancer – Diagnosis and treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/ovarian-cancer/diagnosis-treatment/drc-20375946

  Immunotherapy might be an option for treating ovarian cancer in certain situations. […] Palliative care is specialized medical care that focuses on providing relief from pain and other symptoms of a serious illness. Palliative care specialists work with you, your family and your other doctors to provide an extra layer of support that complements your ongoing care. Palliative care can be used while undergoing other aggressive treatments, such as surgery and chemotherapy. […] When palliative care is used along with all of the other appropriate treatments, people with cancer may feel better and live longer.

• #107 Ovarian Cancer Treatment Options: An In-Depth Guide to Surgery, Chemotherapy, and More | Not These Ovaries

  https://www.nottheseovaries.org/ovarian-cancer-treatment/

  Immunotherapy is a type of cancer treatment that harnesses the power of the body’s immune system to fight cancer cells. […] One established immunotherapy treatment for ovarian cancer is bevacizumab (Avastin), which works by targeting blood vessel growth and is widely used both in combination with chemotherapy and as maintenance therapy. […] Radiation therapy uses high-energy beams, such as X-rays, to kill cancer cells in a specific area of the body. While radiation therapy is not commonly used to treat ovarian cancer, it may be recommended in certain situations, such as treating isolated recurrences or alleviating symptoms like pain. […] Palliative care is an essential aspect of ovarian cancer treatment that focuses on managing symptoms, improving quality of life, and providing emotional support for patients and their families. […] A multidisciplinary palliative care team may include doctors, nurses, social workers, counselors, and other healthcare professionals who work together to address the physical, emotional, and spiritual needs of ovarian cancer patients.

• #108 Ovarian Cancer Treatment | How to Treat Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating.html

  You may hear about alternative or complementary methods to relieve symptoms or treat your cancer that your doctors havent mentioned. […] Be sure to talk to your cancer care team about any method you are thinking about using. […] Whether you are thinking about treatment, getting treatment, or not being treated at all, you can still get supportive care to help with pain or other symptoms. […] For some people, when treatments have been tried and are no longer controlling the cancer, it could be time to weigh the benefits and risks of continuing to try new treatments. […] Remember that even if you choose not to treat the cancer, you can still get supportive care to help with pain or other symptoms. […] Hospice care is designed to provide the best possible quality of life for people who are near the end of life.

• #109 Ovarian Cancer: Treatment Choices

  https://healthlibrary.brighamandwomens.org/RelatedItems/34,17195-1

  Ovarian Cancer: Treatment Choices […] The information here focuses on treatment for epithelial ovarian cancer. Other types of ovarian cancer are rare. […] Your treatment options depend on how much cancer there is, if and how far it has spread (stage), and gene changes in the cancer cells. Your age, overall health, desire to have children, and preferences are also key. […] Cancer may just be in one ovary or may have spread into nearby areas in the pelvis. If so, its called local or early-stage cancer. If it has spread to distant parts of the body (such as your lungs, belly, liver, or bones), its called metastatic or advanced ovarian cancer. Its important that your treatment team learn as much as they can about the cancer. You’ll likely be treated by a gynecologic oncologist. This specialist has advanced training in the diagnosis and treatment of female cancers, such as ovarian cancer.

• #110 Ovarian Cancer | Dana-Farber Cancer Institute

  https://www.dana-farber.org/cancer-care/types/ovarian-cancer

  Your care team will collaborate to develop a comprehensive, personalized treatment plan that offers the most advanced therapies and an array of supportive resources. […] Treatment options include: Surgery, Chemotherapy, Hyperthermic intraperitoneal chemotherapy (HIPEC), Targeted therapy (for certain cases), Radiation therapy (for rare cases). […] Your prognosis and treatment options depend on the following: The stage of your cancer and whether your cancer can be operated on by a gynecologic oncology surgeon, The pathologic subtype of ovarian cancer, Your age and general health, Whether the cancer has just been diagnosed or has come back (recurred), The genetics of your tumor. […] If you or a loved one has ovarian cancer, the team in the Gynecologic Oncology Program at Dana-Farber Brigham Cancer Center is here to help.

• #111 Ovarian cancer: New treatments and research – Mayo Clinic Comprehensive Cancer Center Blog

  https://cancerblog.mayoclinic.org/2024/05/01/ovarian-cancer-new-treatments-and-research/

  „Pembrolizumab is in a category of drugs called immune checkpoint inhibitors,” says Dr. Weroha. „This drug is designed to release the brakes on the immune system to allow it to do what it naturally wants: kill things it doesn’t like. The hope is that the vaccine combined with the immunotherapy drug will kill a lot of ovarian cancer. It’s exciting research.” […] If you’ve been diagnosed with ovarian cancer, Dr. Weroha recommends making an appointment with a gynecologic oncologist. „A gynecologic oncologist will be up to date on the current treatment recommendations and the management of side effects. That’s important,” he says. […] Dr. Weroha also recommends newly diagnosed patients ask their care teams if they are candidates for PARP inhibitors, mirvetuximab or clinical trials. „PARP inhibitors and mirvetuximab are newer treatments that could influence the outcome of your overall treatment. Always ask about clinical trials because when ovarian cancer recurs, there is no treatment so good that we can stop looking for something better,” he says.

• #112 Ovarian Cancer Treatment | How to Treat Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating.html

  Typically, treatment plans are based on the type of ovarian cancer, its stage, and any special situations. Most women with ovarian cancer will have some type of surgery to remove the tumor. […] Depending on the type of ovarian cancer and how advanced it is, you might need other types of treatment as well, either before or after surgery, or sometimes both. […] Based on your treatment options, you might have different types of doctors on your treatment team. […] Your treatment plan will depend on many factors, including your overall health, personal preferences, and whether you plan to have children. […] Its important to discuss all of your treatment options, including their goals and possible side effects, with your doctors to help make the decision that best fits your needs. […] Clinical trials are carefully controlled research studies that are done to get a closer look at promising new treatments or procedures.

• #113 Treatment of Ovarian Cancer | Ovarian Cancer | CDC

  https://www.cdc.gov/ovarian-cancer/treatment/index.html

  Talk to your cancer doctor about the treatment options available for your type and stage of cancer. Your doctor can explain the risks and benefits of each treatment and their side effects. […] Sometimes people get an opinion from more than one cancer doctor. This is called a „second opinion.” Getting a second opinion may help you choose the treatment that is right for you. […] Clinical trials use new treatment options to see if they are safe and effective. If you have cancer, you may want to take part. […] Complementary and alternative medicine are medicines and health practices that are not standard cancer treatments. Complementary medicine is used in addition to standard treatments. Alternative medicine is used instead of standard treatments. […] Talk to your doctor about the risks and benefits before you start any kind of complementary or alternative medicine.

• #114 Ovarian Cancer Treatment | How to Treat Ovarian Cancer | American Cancer Society

  https://www.cancer.org/cancer/types/ovarian-cancer/treating.html

  You may hear about alternative or complementary methods to relieve symptoms or treat your cancer that your doctors havent mentioned. […] Be sure to talk to your cancer care team about any method you are thinking about using. […] Whether you are thinking about treatment, getting treatment, or not being treated at all, you can still get supportive care to help with pain or other symptoms. […] For some people, when treatments have been tried and are no longer controlling the cancer, it could be time to weigh the benefits and risks of continuing to try new treatments. […] Remember that even if you choose not to treat the cancer, you can still get supportive care to help with pain or other symptoms. […] Hospice care is designed to provide the best possible quality of life for people who are near the end of life.

• #115

  https://winshipcancer.emory.edu/cancer-types-and-treatments/ovarian-cancer/

  No two ovarian cancers are alike. At Winship Cancer Institute of Emory University, youll receive the personalized care you need to treat your cancer. […] Our gynecologic oncology team is made up of top-ranked specialists. They analyze and treat every case of ovarian cancer individually, and with investigational treatments whenever possible because your cancer is unique, and it should be treated that way. […] Your individual treatment plan relies on a precise diagnosis. […] We look beyond your cancers stage to find out whats driving its growth at the molecular level. Then we design a treatment plan to target your specific ovarian cancer with precise, powerful treatments while minimizing side effects. […] With more clinical trials than any other cancer center in Georgia, youll have access at Winship to the most advanced and innovative treatments and resources for treating your specific ovarian cancer.

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