Materiały źródłowe

• #1 Paget’s Disease of Bone Causes, Symptoms, Treatment, Medications, Prevention

  https://www.medicinenet.com/pagets_disease/article.htm

  Is it possible to prevent Paget’s disease? […] There is no way to prevent Paget’s disease of bone.

• #2 Paget’s Disease vs. Osteoporosis: Causes, Treatment, and More

  https://www.healthline.com/health/pagets-disease-vs-osteoporosis

  The cause of Paget disease of bone isnt clear, and there isnt a known way to prevent it. […] You may be able to prevent osteoporosis by: staying physically active by participating in weight-bearing exercises […] drinking alcohol in moderation or not at all […] quitting smoking or not starting if you dont smoke […] taking your medication as prescribed […] eating a balanced diet high in calcium and vitamin D.

• #3 Paget’s Disease of the Bone: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/21929-pagets-disease-of-the-bone

  Unfortunately, theres nothing you can do to prevent Pagets disease of the bone. […] There are some things that are considered risk factors for developing Pagets disease of the bone, including: […] People over the age of 50 are more likely to develop Pagets disease of the bone. […] Pagets disease of the bone is more common in European populations, including those living in England, Italy and Spain. […] Males are slightly more at risk. […] Pagets disease of the bone can sometimes run in families. If you have a family member who has the disease, you may be more likely to develop it.

• #4 Paget Disease Treatment & Management: Approach Considerations, Bisphosphonates and Calcitonin Analogues, Neoplasm

  https://emedicine.medscape.com/article/334607-treatment

  The short-term objective of Paget disease treatment is to control disease activity. The long-term objectives are to minimize or prevent disease progression and to decrease complications from the disease, if possible. […] When Paget disease occurs around a joint, treatment is often administered in an attempt to prevent development of osteoarthritis. In addition, young patients with Paget disease and those with high levels of bone-specific alkaline phosphatase (BSAP) are often treated to avoid future complications. Indirect evidence, and one long-term placebo-controlled trial, support the concept that prophylaxis may help prevent progression and reduction in risk of future complications. […] A randomized, controlled study reported that in people with a family history of PDB, genetic testing for pathogenic SQSTM1 variants coupled with radionuclide bone scan examination in those found to be SQSTM1 positive can identify individuals who may benefit from prophylactic bisphosphonate treatment. […] A patient who has a family history of Paget disease and is older than 40 years may wish to have serum alkaline phosphatase measured every 2-3 years. If the alkaline phosphatase level is within the reference range, radiography or bone scanning also may be performed.

• #5 Paget’s Disease: Prevention And Treatment. — Best Bainbridge Island Physical Therapy Clinic For Pain Relief, Injury Prevention & Rehabilitation

  https://fiziologix.com/blog-fiziologix-physical-therapy-tips-and-self-healing/4/15/2023/pagets-disease-symptoms-prevention-treatment-similar-conditions

  While there is no known way to prevent Paget’s disease, some lifestyle modifications may help maintain healthy bone density, such as regular exercise, a balanced diet rich in calcium and vitamin D, and avoiding smoking and excessive alcohol consumption. […] It’s also important to get regular bone density screenings, especially if you are at risk for developing Paget’s disease or other bone disorders.

• #6 Paget Disease Treatment & Management: Approach Considerations, Bisphosphonates and Calcitonin Analogues, Neoplasm

  https://emedicine.medscape.com/article/334607-treatment

  The short-term objective of Paget disease treatment is to control disease activity. The long-term objectives are to minimize or prevent disease progression and to decrease complications from the disease, if possible. […] When Paget disease occurs around a joint, treatment is often administered in an attempt to prevent development of osteoarthritis. In addition, young patients with Paget disease and those with high levels of bone-specific alkaline phosphatase (BSAP) are often treated to avoid future complications. Indirect evidence, and one long-term placebo-controlled trial, support the concept that prophylaxis may help prevent progression and reduction in risk of future complications. […] A randomized, controlled study reported that in people with a family history of PDB, genetic testing for pathogenic SQSTM1 variants coupled with radionuclide bone scan examination in those found to be SQSTM1 positive can identify individuals who may benefit from prophylactic bisphosphonate treatment. […] A patient who has a family history of Paget disease and is older than 40 years may wish to have serum alkaline phosphatase measured every 2-3 years. If the alkaline phosphatase level is within the reference range, radiography or bone scanning also may be performed.

• #7 Paget’s disease of bone – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/pagets-disease-of-bone/diagnosis-treatment/drc-20350816

  If the disease is active indicated by an elevated alkaline phosphatase level and is affecting high-risk sites in your body, such as your skull or spine, your doctor might recommend treatment to prevent complications, even if you don’t have symptoms. […] To reduce your risk of complications associated with Paget’s disease of bone, try these tips: […] Paget’s disease of bone puts you at high risk of bone fractures. Ask your doctor for advice on preventing falls. […] Be sure your diet includes adequate levels of calcium and vitamin D, which helps bones absorb calcium. […] Regular exercise is essential for maintaining joint mobility and bone strength.

• #8 Paget’s Disease of Bone | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.paget’s-disease-of-bone.hw191694

  Many people don’t need treatment for Paget’s disease. But even if you don’t need treatment, you will still need to see your doctor on a regular basis from now on. This will let your doctor watch for other problems you might get from the disease, such as arthritis, fractures, or nerve problems. […] Your doctor may prescribe medicine if you have symptoms or if you have no symptoms but you are at risk for other problems from Paget’s disease. Medicine can help reduce the breakdown of bone tissue, control symptoms such as bone pain, and prevent other problems such as arthritis, fractures, or nerve damage. […] Physical therapy to build your muscles and improve your balance. This can help reduce falls and prevent broken bones. […] Do weight-bearing exercise to keep your bones strong. Walking, dancing, or lifting weights may be good, but make sure that you don’t put stress on affected bones. Your doctor or physical therapist can suggest exercises for you. […] Eat a healthy diet that includes plenty of calcium and vitamin D. You need both to build strong bones.

• #9 Paget’s Disease: Causes, Symptoms, and Treatments | Arthritis Foundation

  https://www.arthritis.org/diseases/pagets-disease

  Taking a proactive role in treatment a process called self-management is important. Here are some ways to help manage the disease: […] To maintain strong bones, you should get 1,200 mg of calcium and at least 400 IU of vitamin D every day. After age 70, you should take 600 IU of vitamin D each day. If you have had kidney stones, talk with your doctor about how much calcium and vitamin D to take. […] Exercise helps keep joints mobile and build strong bones. Talk to a doctor or a physical therapist before starting an exercise program to choose the most appropriate exercises.

• #10 Paget’s Disease of Bone | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.paget’s-disease-of-bone.hw191694

  Many people don’t need treatment for Paget’s disease. But even if you don’t need treatment, you will still need to see your doctor on a regular basis from now on. This will let your doctor watch for other problems you might get from the disease, such as arthritis, fractures, or nerve problems. […] Your doctor may prescribe medicine if you have symptoms or if you have no symptoms but you are at risk for other problems from Paget’s disease. Medicine can help reduce the breakdown of bone tissue, control symptoms such as bone pain, and prevent other problems such as arthritis, fractures, or nerve damage. […] Physical therapy to build your muscles and improve your balance. This can help reduce falls and prevent broken bones. […] Do weight-bearing exercise to keep your bones strong. Walking, dancing, or lifting weights may be good, but make sure that you don’t put stress on affected bones. Your doctor or physical therapist can suggest exercises for you. […] Eat a healthy diet that includes plenty of calcium and vitamin D. You need both to build strong bones.

• #11 PAGET’S DISEASE OF BONE: SYMPTOMS, DIAGNOSIS, TREATMENT AND MORE | Mya Care

  https://myacare.com/blog/pagets-disease-of-bone-symptoms-diagnosis-treatment-and-more

  While there is no known way to prevent Paget’s disease, maintaining a healthy lifestyle and avoiding known triggers, such as viral infections, may help reduce your risk of developing the condition. […] Calcium and vitamin D supplementation are advisable for those on bisphosphonates to ensure adequate intake. […] Speak to a nutritionist about supplementation for maintaining optimal bone health and turnover.

• #12 Paget’s disease of bone – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/pagets-disease-of-bone/diagnosis-treatment/drc-20350816

  If the disease is active indicated by an elevated alkaline phosphatase level and is affecting high-risk sites in your body, such as your skull or spine, your doctor might recommend treatment to prevent complications, even if you don’t have symptoms. […] To reduce your risk of complications associated with Paget’s disease of bone, try these tips: […] Paget’s disease of bone puts you at high risk of bone fractures. Ask your doctor for advice on preventing falls. […] Be sure your diet includes adequate levels of calcium and vitamin D, which helps bones absorb calcium. […] Regular exercise is essential for maintaining joint mobility and bone strength.

• #13 Paget’s disease of bone: Symptoms, causes, and treatment

  https://www.medicalnewstoday.com/articles/177668

  Pagets Disease is unavoidable for most people with the disorder, but exercise can help to maintain skeletal health, avoid weight gain to relieve pressure on the joints and bones, and maintain joint mobility. […] People with the disease should talk to their physician before starting any exercise program, as placing extra stress on bones affected by Pagets disease can lead to injury.

• #14 Paget’s Disease Cypress TX | Hip Pain Cypress | Osteoporosis Houston TX

  https://www.advancedosm.com/pagets-disease/

  Paget’s disease of bone is a chronic condition characterized by abnormal bone remodeling, leading to enlarged and weakened bones. […] Effective management of Paget’s disease requires specialized care to monitor bone health and address symptoms. […] The goals are to reduce bone pain, slow the progression of the condition and prevent complications. […] In general, exercise is very beneficial for individuals who have Pagets Disease. With regular physical activity, it may be possible to maintain a healthy body weight, prevent joint stiffness and improve bone health. […] Any proposed exercise program should be discussed with a physician who can confirm that the planned activities can be safely performed without overly stressing the bones affected by Pagets Disease.

• #15 Paget’s Disease of Bone | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.paget’s-disease-of-bone.hw191694

  Many people don’t need treatment for Paget’s disease. But even if you don’t need treatment, you will still need to see your doctor on a regular basis from now on. This will let your doctor watch for other problems you might get from the disease, such as arthritis, fractures, or nerve problems. […] Your doctor may prescribe medicine if you have symptoms or if you have no symptoms but you are at risk for other problems from Paget’s disease. Medicine can help reduce the breakdown of bone tissue, control symptoms such as bone pain, and prevent other problems such as arthritis, fractures, or nerve damage. […] Physical therapy to build your muscles and improve your balance. This can help reduce falls and prevent broken bones. […] Do weight-bearing exercise to keep your bones strong. Walking, dancing, or lifting weights may be good, but make sure that you don’t put stress on affected bones. Your doctor or physical therapist can suggest exercises for you. […] Eat a healthy diet that includes plenty of calcium and vitamin D. You need both to build strong bones.

• #16 Paget’s disease of bone – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/pagets-disease-of-bone/diagnosis-treatment/drc-20350816

  If the disease is active indicated by an elevated alkaline phosphatase level and is affecting high-risk sites in your body, such as your skull or spine, your doctor might recommend treatment to prevent complications, even if you don’t have symptoms. […] To reduce your risk of complications associated with Paget’s disease of bone, try these tips: […] Paget’s disease of bone puts you at high risk of bone fractures. Ask your doctor for advice on preventing falls. […] Be sure your diet includes adequate levels of calcium and vitamin D, which helps bones absorb calcium. […] Regular exercise is essential for maintaining joint mobility and bone strength.

• #17

  https://myhealth.alberta.ca/Health/pages/conditions.aspx?hwid=hw191694

  Many people don’t need treatment for Paget’s disease. But even if you don’t need treatment, you will still need to see your doctor on a regular basis from now on. This will let your doctor watch for other problems you might get from the disease, such as arthritis, fractures, or nerve problems. […] Your doctor may prescribe medicine if you have symptoms or if you have no symptoms but you are at risk for other problems from Paget’s disease. Medicine can help reduce the breakdown of bone tissue, control symptoms such as bone pain, and prevent other problems such as arthritis, fractures, or nerve damage. […] Physiotherapy to build your muscles and improve your balance. This can help reduce falls and prevent broken bones. […] Take care to avoid falls. For example, keep your home’s walkways free of clutter and electric cords. Put grab bars in your bathroom.

• #18 Paget’s Disease of Bone | Orthopedics & Sports Medicine

  https://health.uconn.edu/orthopedics-sports-medicine/conditions-and-treatments/a-z-index/pagets-disease-of-bone/

  Medical treatments can help decrease the symptoms of Paget’s disease, but there is no known way to reverse the effects on the bone. […] If you arent experiencing symptoms, your doctor may only call for observation. Periodic X-rays may be recommended to watch for any changes. […] If you are experiencing mild pain, nonsteroidal anti-inflammatories (NSAIDs) and aspirin can be very helpful. When the pelvis or leg is involved, using a cane can decrease pain by reducing the forces impacting the bone. A cane can also help prevent falls, so there is less risk of fracture. Braces may be used to prevent malalignment of the bones. […] Because Pagets diseases increases the blood supply to your bones, your doctor may recommend bisphosphonates before the surgery to reduce potential blood loss.

• #19 Paget’s Disease of Bone | Orthopedics & Sports Medicine

  https://health.uconn.edu/orthopedics-sports-medicine/conditions-and-treatments/a-z-index/pagets-disease-of-bone/

  Medical treatments can help decrease the symptoms of Paget’s disease, but there is no known way to reverse the effects on the bone. […] If you arent experiencing symptoms, your doctor may only call for observation. Periodic X-rays may be recommended to watch for any changes. […] If you are experiencing mild pain, nonsteroidal anti-inflammatories (NSAIDs) and aspirin can be very helpful. When the pelvis or leg is involved, using a cane can decrease pain by reducing the forces impacting the bone. A cane can also help prevent falls, so there is less risk of fracture. Braces may be used to prevent malalignment of the bones. […] Because Pagets diseases increases the blood supply to your bones, your doctor may recommend bisphosphonates before the surgery to reduce potential blood loss.

• #20 Paget’s Disease: Prevention And Treatment. — Best Bainbridge Island Physical Therapy Clinic For Pain Relief, Injury Prevention & Rehabilitation

  https://fiziologix.com/blog-fiziologix-physical-therapy-tips-and-self-healing/4/15/2023/pagets-disease-symptoms-prevention-treatment-similar-conditions

  While there is no known way to prevent Paget’s disease, some lifestyle modifications may help maintain healthy bone density, such as regular exercise, a balanced diet rich in calcium and vitamin D, and avoiding smoking and excessive alcohol consumption. […] It’s also important to get regular bone density screenings, especially if you are at risk for developing Paget’s disease or other bone disorders.

• #21 Paget’s Disease vs. Osteoporosis: Causes, Treatment, and More

  https://www.healthline.com/health/pagets-disease-vs-osteoporosis

  The cause of Paget disease of bone isnt clear, and there isnt a known way to prevent it. […] You may be able to prevent osteoporosis by: staying physically active by participating in weight-bearing exercises […] drinking alcohol in moderation or not at all […] quitting smoking or not starting if you dont smoke […] taking your medication as prescribed […] eating a balanced diet high in calcium and vitamin D.

• #22 Paget’s disease of bone: Symptoms, causes, and treatment

  https://www.medicalnewstoday.com/articles/177668

  Pagets Disease is unavoidable for most people with the disorder, but exercise can help to maintain skeletal health, avoid weight gain to relieve pressure on the joints and bones, and maintain joint mobility. […] People with the disease should talk to their physician before starting any exercise program, as placing extra stress on bones affected by Pagets disease can lead to injury.

• #23 Paget’s disease: Diagnosis, Prevention and Treatment

  https://www.yashodahospitals.com/diseases-treatments/pagets-disease-diagnosis-prevention-treatment/

  Some preventive measures an individual can take are: […] Regular exercise […] Avoid gain in weight […] Relieve pressure on the joints and bones by stretching, etc.

• #24 Paget’s Disease of Bone | Endocrine Society

  https://www.endocrine.org/clinical-practice-guidelines/pagets-disease-of-bone

  We suggest treatment with a bisphosphonate for most patients with active Paget’s disease who are at risk for future complications. […] We suggest that bisphosphonate treatment may be effective in preventing or slowing the progress of hearing loss and osteoarthritis in joints adjacent to Paget’s disease and may reverse paraplegia associated with spinal Paget’s disease. […] We suggest treatment with a bisphosphonate before surgery on pagetic bone.

• #25 Paget Disease Treatment & Management: Approach Considerations, Bisphosphonates and Calcitonin Analogues, Neoplasm

  https://emedicine.medscape.com/article/334607-treatment

  The short-term objective of Paget disease treatment is to control disease activity. The long-term objectives are to minimize or prevent disease progression and to decrease complications from the disease, if possible. […] When Paget disease occurs around a joint, treatment is often administered in an attempt to prevent development of osteoarthritis. In addition, young patients with Paget disease and those with high levels of bone-specific alkaline phosphatase (BSAP) are often treated to avoid future complications. Indirect evidence, and one long-term placebo-controlled trial, support the concept that prophylaxis may help prevent progression and reduction in risk of future complications. […] A randomized, controlled study reported that in people with a family history of PDB, genetic testing for pathogenic SQSTM1 variants coupled with radionuclide bone scan examination in those found to be SQSTM1 positive can identify individuals who may benefit from prophylactic bisphosphonate treatment. […] A patient who has a family history of Paget disease and is older than 40 years may wish to have serum alkaline phosphatase measured every 2-3 years. If the alkaline phosphatase level is within the reference range, radiography or bone scanning also may be performed.

• #26 Paget’s Disease of Bone

  https://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/rheumatology/pagets-disease-of-bone/

  The indications for treatment of PDB include bone pain, bone deformity, extensive skull involvement, hypercalcemia, fractures, neurologic compromise, monostotic disease of a tibia or femur in whom progression is likely, and high-output heart failure. Treatment is also indicated in the presence of moderately active asymptomatic disease, with serum alkaline phosphatase at least 3 to 4 times the upper limit of normal, in patients with disease at sites where complications could occur. […] For patients with moderately active disease before elective surgery on the affected bone(s), prophylactic therapy is also used to reduce hypervascularity and blood loss. Some studies indicate that antipagetic treatment is valuable for symptomatic as well as asymptomatic patients, with the goal of reducing local disease progression and the risk of future complications. […] In general, because therapy is effective and safe, treatment should be withheld only in asymptomatic patients whose disease is located only in areas with no risk of complications.

• #27 Paget’s disease of bone: who to treat and why it matters | Endocrinology Today

  https://endocrinology.medicinetoday.com.au/et/2018/february/feature-article/pagets-disease-bone-who-treat-and-why-it-matters

  Bisphosphonates are highly effective in suppressing bone turnover and are the mainstay of treatment for Pagets disease. […] However, before treatment, all patients should have their serum calcium levels checked and be made vitamin D replete (50nmol/L) to prevent hypocalcaemia. […] Therapy should be offered to all patients with bone pain or established complications of Pagets disease. […] People with asymptomatic Pagets disease generally do not require treatment; however, if the site of the disease increases the risk of future complications (e.g. vertebral involvement leading to spinal cord compression) then treatment should be considered. […] This decision must be made on a patient-by-patient basis, as randomised controlled trial evidence has not shown treatment of asymptomatic patients to have significant benefit in terms of fractures, hearing loss, joint replacement, future bone pain or quality-of-life measures. […] In patients requiring surgery on Pagets-affected bone, there is a role for pretreatment with bisphosphonates to reduce operative blood loss.

• #28 Guidelines for Paget’s Disease of the Bone Released – Endocrinology Advisor

  https://www.endocrinologyadvisor.com/news/guidelines-for-pagets-disease-of-the-bone-released/

  In the guideline, the task force recommends that bisphosphonates be prescribed for patients with active Pagets disease at risk for future complications. […] Additionally, the task force suggest that bisphosphonate treatment may help prevent or slow hearing loss or osteoarthritis in the joints adjacent to Pagets disease and potentially reverse paraplegia associated with spinal Pagets disease. […] They also suggest treatment with a bisphosphonate before surgery on pagetic bone.

• #29 Paget’s Disease of Bone | Orthopedics & Sports Medicine

  https://health.uconn.edu/orthopedics-sports-medicine/conditions-and-treatments/a-z-index/pagets-disease-of-bone/

  Medical treatments can help decrease the symptoms of Paget’s disease, but there is no known way to reverse the effects on the bone. […] If you arent experiencing symptoms, your doctor may only call for observation. Periodic X-rays may be recommended to watch for any changes. […] If you are experiencing mild pain, nonsteroidal anti-inflammatories (NSAIDs) and aspirin can be very helpful. When the pelvis or leg is involved, using a cane can decrease pain by reducing the forces impacting the bone. A cane can also help prevent falls, so there is less risk of fracture. Braces may be used to prevent malalignment of the bones. […] Because Pagets diseases increases the blood supply to your bones, your doctor may recommend bisphosphonates before the surgery to reduce potential blood loss.

• #30 Paget’s disease of bone: who to treat and why it matters | Endocrinology Today

  https://endocrinology.medicinetoday.com.au/et/2018/february/feature-article/pagets-disease-bone-who-treat-and-why-it-matters

  Bisphosphonates are highly effective in suppressing bone turnover and are the mainstay of treatment for Pagets disease. […] However, before treatment, all patients should have their serum calcium levels checked and be made vitamin D replete (50nmol/L) to prevent hypocalcaemia. […] Therapy should be offered to all patients with bone pain or established complications of Pagets disease. […] People with asymptomatic Pagets disease generally do not require treatment; however, if the site of the disease increases the risk of future complications (e.g. vertebral involvement leading to spinal cord compression) then treatment should be considered. […] This decision must be made on a patient-by-patient basis, as randomised controlled trial evidence has not shown treatment of asymptomatic patients to have significant benefit in terms of fractures, hearing loss, joint replacement, future bone pain or quality-of-life measures. […] In patients requiring surgery on Pagets-affected bone, there is a role for pretreatment with bisphosphonates to reduce operative blood loss.

• #31 Paget’s Disease of Bone – Zero To Finals

  https://zerotofinals.com/medicine/rheumatology/pagetsdisease/

  Bisphosphonates are the main treatment. They are generally very effective. They interfere with osteoclast activity and restore normal bone metabolism. They improve symptoms and prevent further abnormal bone changes. […] Other measures include: […] Calcium and vitamin D supplementation, if necessary. […] Monitoring involves checking the serum alkaline phosphatase (ALP) and reviewing symptoms. Effective treatment should normalise the ALP and eliminate symptoms.

• #32 Paget’s Disease of Bone | Endocrine Society

  https://www.endocrine.org/clinical-practice-guidelines/pagets-disease-of-bone

  We suggest treatment with a bisphosphonate for most patients with active Paget’s disease who are at risk for future complications. […] We suggest that bisphosphonate treatment may be effective in preventing or slowing the progress of hearing loss and osteoarthritis in joints adjacent to Paget’s disease and may reverse paraplegia associated with spinal Paget’s disease. […] We suggest treatment with a bisphosphonate before surgery on pagetic bone.

• #33 Guidelines for Paget’s Disease of the Bone Released – Endocrinology Advisor

  https://www.endocrinologyadvisor.com/news/guidelines-for-pagets-disease-of-the-bone-released/

  In the guideline, the task force recommends that bisphosphonates be prescribed for patients with active Pagets disease at risk for future complications. […] Additionally, the task force suggest that bisphosphonate treatment may help prevent or slow hearing loss or osteoarthritis in the joints adjacent to Pagets disease and potentially reverse paraplegia associated with spinal Pagets disease. […] They also suggest treatment with a bisphosphonate before surgery on pagetic bone.

• #34 Paget’s disease of bone: who to treat and why it matters | Endocrinology Today

  https://endocrinology.medicinetoday.com.au/et/2018/february/feature-article/pagets-disease-bone-who-treat-and-why-it-matters

  Bisphosphonates are highly effective in suppressing bone turnover and are the mainstay of treatment for Pagets disease. […] However, before treatment, all patients should have their serum calcium levels checked and be made vitamin D replete (50nmol/L) to prevent hypocalcaemia. […] Therapy should be offered to all patients with bone pain or established complications of Pagets disease. […] People with asymptomatic Pagets disease generally do not require treatment; however, if the site of the disease increases the risk of future complications (e.g. vertebral involvement leading to spinal cord compression) then treatment should be considered. […] This decision must be made on a patient-by-patient basis, as randomised controlled trial evidence has not shown treatment of asymptomatic patients to have significant benefit in terms of fractures, hearing loss, joint replacement, future bone pain or quality-of-life measures. […] In patients requiring surgery on Pagets-affected bone, there is a role for pretreatment with bisphosphonates to reduce operative blood loss.

• #35 Paget’s Disease of Bone | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.paget’s-disease-of-bone.hw191694

  Many people don’t need treatment for Paget’s disease. But even if you don’t need treatment, you will still need to see your doctor on a regular basis from now on. This will let your doctor watch for other problems you might get from the disease, such as arthritis, fractures, or nerve problems. […] Your doctor may prescribe medicine if you have symptoms or if you have no symptoms but you are at risk for other problems from Paget’s disease. Medicine can help reduce the breakdown of bone tissue, control symptoms such as bone pain, and prevent other problems such as arthritis, fractures, or nerve damage. […] Physical therapy to build your muscles and improve your balance. This can help reduce falls and prevent broken bones. […] Do weight-bearing exercise to keep your bones strong. Walking, dancing, or lifting weights may be good, but make sure that you don’t put stress on affected bones. Your doctor or physical therapist can suggest exercises for you. […] Eat a healthy diet that includes plenty of calcium and vitamin D. You need both to build strong bones.

• #36 Paget’s Disease of Bone – Women’s Health – Associates for Women’s Medicine – Syracuse NY Gynecologist, Gynecology, Obstetrics, OBGYN, OB Physicians, Syracuse New York, Fayetteville, North Syracuse, LiverpoolPaget’s Disease of Bone

  https://www.afwomensmed.com/health-library/hw-view.php?DOCHWID=hw191694

  Many people don’t need treatment for Paget’s disease. But even if you don’t need treatment, you will still need to see your doctor on a regular basis from now on. This will let your doctor watch for other problems you might get from the disease, such as arthritis, fractures, or nerve problems. […] Your doctor may prescribe medicine if you have symptoms or if you have no symptoms but you are at risk for other problems from Paget’s disease. Medicine can help reduce the breakdown of bone tissue, control symptoms such as bone pain, and prevent other problems such as arthritis, fractures, or nerve damage. […] Physical therapy to build your muscles and improve your balance. This can help reduce falls and prevent broken bones. […] Take care to avoid falls. For example, keep your home’s walkways free of clutter and electric cords. Put grab bars in your bathroom.

• #37 Paget’s Disease of Bone – Zero To Finals

  https://zerotofinals.com/medicine/rheumatology/pagetsdisease/

  Bisphosphonates are the main treatment. They are generally very effective. They interfere with osteoclast activity and restore normal bone metabolism. They improve symptoms and prevent further abnormal bone changes. […] Other measures include: […] Calcium and vitamin D supplementation, if necessary. […] Monitoring involves checking the serum alkaline phosphatase (ALP) and reviewing symptoms. Effective treatment should normalise the ALP and eliminate symptoms.

• #38 Paget’s Disease of Bone – Zero To Finals

  https://zerotofinals.com/medicine/rheumatology/pagetsdisease/

  Bisphosphonates are the main treatment. They are generally very effective. They interfere with osteoclast activity and restore normal bone metabolism. They improve symptoms and prevent further abnormal bone changes. […] Other measures include: […] Calcium and vitamin D supplementation, if necessary. […] Monitoring involves checking the serum alkaline phosphatase (ALP) and reviewing symptoms. Effective treatment should normalise the ALP and eliminate symptoms.

• #39 Paget’s Disease of Bone | Med Diagnostics Rehab

  https://www.meddiagnosticrehab.co/pagets-disease-of-bone.php

  Patients who are asymptomatic may not require any treatment, but are advised to be proactive in preserving bone health by eating a healthy diet with sufficient levels of calcium and vitamin D, and by exercising regularly to keep their joints mobile. […] Paget’s disease progresses slowly, and most people with the disease can be treated effectively.

• #40 Paget’s Disease of Bone | Tampa Rheumatology

  https://www.tamparheumatology.com/pagets-disease-of-bone.php

  Patients who are asymptomatic may not require any treatment, but are advised to be proactive in preserving bone health by eating a healthy diet with sufficient levels of calcium and vitamin D, and by exercising regularly to keep their joints mobile. […] When symptoms are present, depending on their severity, one or more of the following medications or surgeries may be necessary: Bisphosphonates (osteoporosis medications), Calcitonin, a hormone to regulate bone metabolism, Surgery to repair fractured or deformed bone, Surgery to relieve nerve compression, Surgery to replace joints damaged by arthritis.

• #41 Paget’s Disease Cypress TX | Hip Pain Cypress | Osteoporosis Houston TX

  https://www.advancedosm.com/pagets-disease/

  Paget’s disease of bone is a chronic condition characterized by abnormal bone remodeling, leading to enlarged and weakened bones. […] Effective management of Paget’s disease requires specialized care to monitor bone health and address symptoms. […] The goals are to reduce bone pain, slow the progression of the condition and prevent complications. […] In general, exercise is very beneficial for individuals who have Pagets Disease. With regular physical activity, it may be possible to maintain a healthy body weight, prevent joint stiffness and improve bone health. […] Any proposed exercise program should be discussed with a physician who can confirm that the planned activities can be safely performed without overly stressing the bones affected by Pagets Disease.

• #42 Paget’s Disease of Bone | Med Diagnostics Rehab

  https://www.meddiagnosticrehab.co/pagets-disease-of-bone.php

  Patients who are asymptomatic may not require any treatment, but are advised to be proactive in preserving bone health by eating a healthy diet with sufficient levels of calcium and vitamin D, and by exercising regularly to keep their joints mobile. […] Paget’s disease progresses slowly, and most people with the disease can be treated effectively.

Zobacz więcej