Materiały źródłowe

• #1 Rosacea: Practical Guidance and Challenges for Management | CCID

  https://www.dovepress.com/rosacea-practical-guidance-and-challenges-for-clinical-management-peer-reviewed-fulltext-article-CCID

  Rosacea is a common chronic dermatosis with a prevalence of approximately 5.46% of the global population. However, prevalence is theoretically higher as these percentages do not account for patients with milder, unrecognized disease. […] The first reported account of rosacea was in the 14th century by Dr Guy de Chauliac, a French surgeon, who described red lesions on the face and termed the condition goutteroseFrench for pink dropletor couperose, which remains as a term still used in French medical language. […] In 2002, the National Rosacea Society Expert Committee developed a subtype-based standardized classification system. […] The proportions of those affected by rosacea were found to be 56.7% (95% CI, 51.462.0%) for erythematotelangiectatic rosacea (ETR), 43.2% (95% CI, 38.847.6%) for the papulopustular subtype (PPR), 7.4% (95% CI, 6.18.9%) the phymatous subtype, and 11.1% (95% CI, 6.716.3%) the ocular subtype.

• #1 Burden of Disease: The Psychosocial Impact of Rosacea on a Patient’s Quality of Life

  https://www.ahdbonline.com/articles/1484-feature-1484

  Rosacea is more prevalent in fair-skinned people of Northern European and Eastern European descent, but it has also been reported in people of other ethnicities. Women are more frequently affected than men, with onset of this condition generally occurring between the ages of 30 and 50 years, although rosacea has been reported in the teenaged years. […] Rosacea affects more than 16 million people in the United States. Between 1990 and 1997, there were approximately 1.1 million outpatient visits, annually, for rosacea in the United States. […] Although this is a relatively small patient population, patients with rosacea seek treatment because of the burden of their disease and their poor quality of life. […] The goal of current therapies is to manage the clinical signs and the physical symptoms of rosacea, but the impact of rosacea on patients emotional health and quality of life is sometimes overlooked.

• #1 Epidemiology of rosacea: updated data – EM consulte

  https://www.em-consulte.com/article/680652/epidemiology-of-rosacea-updated-data

  Epidemiology of rosacea: updated data – 17/12/11 […] The epidemiological data on rosacea remain fragmentary and the methodological quality debatable. Rosacea affects mainly adults around the age of 30 years and classically predominates in females. Recent Estonian and Irish studies suggest that the female predominance may not be as high as previously believed. However, prevalence does increase with age. The prevalence statistics published in Europe and the United States are highly variable, ranging from less than 1% to more than 20% of the adult population; actually, the methods used and the populations studied vary greatly from one study to another; consequently, they cannot be compared. A family history of the disease is a risk factor, as is the very light skin phototype (Celtic skin type). Alcohol and coffee, classically blamed, are not risk factors; however, tobacco may have a protective effect. New studies are undoubtedly necessary: they should use the diagnostic and severity criteria established in 2002 and 2004. Rosacea has a strong impact on quality of life and can be associated with depressive symptoms. A specific quality-of-life scale, the RosaQol, has been established and validated in the United States, by the same group that elaborated the Skindex scale. Translations of this scale into French, Italian, German, and Spanish have been validated, which may allow future intercultural comparisons. […]

• #1 Rosacea and Rhinophyma: Symptoms and Treatment | Doctor

  https://patient.info/doctor/rosacea-and-rhinophyma

  Rosacea is a chronic relapsing inflammatory skin disease with a high prevalence among adults of Northern European heritage with fair skin. […] In Europe, there is an increasing prevalence from South to North: in Germany prevalence is 2.2%, in Sweden 10% and in Estonia 22%. […] Rosacea is primarily a condition of the white population; it is three times more common in women than in men and has a peak age of onset between 30 and 60 years. […] For a diagnosis to be confirmed the erythema should have been present for at least three months.

• #1 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Rosacea-Epidemiology.aspx

  Rosacea is a common but under-diagnosed condition of the facial skin that affects around 10% of all individuals. […] In the United States, the prevalence of rosacea seems to be on the rise and in the United Kingdom, the prevalence is 1.65 per 1000 person-years. […] There is a paucity of epidemiological data on rosacea, with reported prevalence rates ranging from as little as 0.09% to as much as 22.00%. […] The condition is most common among individuals aged 30 to 50 years and women are two to three times more likely to be affected than men, with women of menopausal age at a greater risk still. […] The condition often goes undiagnosed among dark-skinned individuals who may have a different clinical presentation to fair-skinned people and suffer more from complications such as conjunctivitis and blepharitis (eyelid swelling). […] In one study examining the prevalence of rosacea subtypes, 14.8 % of women had type 1 or erythematotelangiectatic rosacea while only 1.5% had the second type, papulopustular rosacea.

• #1 New Study Estimates Rosacea’s Worldwide Prevalence | Rosacea.org

  https://www.rosacea.org/blog/2024/may/new-study-estimates-rosaceas-worldwide-prevalence

  A new study on the global epidemiology of rosacea and acne offers a new estimate of how many people may have rosacea worldwide. The study, which was conducted on 50,552 individuals older than 16 from 20 countries that comprise more than half of the worlds population, found an overall rosacea prevalence of 5.1%. An earlier study that pooled data from 32 population-based studies comprising 26.5 million people found a similar prevalence of 5.46%, though those researchers noted that the proportions in individual studies varied widely and were higher when rosacea was self-reported. […] Whereas past studies and NRS surveys have indicated that fair-skinned individuals with a northern European background were more prone to developing the disorder, the new study reported the greatest prevalence in East Asia (4%), followed by Latin America (3.5%), the Middle East (3.4%), Australia (3.2%) and then Europe (3.1%). The researchers also found that people of mixed ethnicity showed the highest prevalence of rosacea (4.3%), followed by whites (3.3%), Asians (3.1%) and Blacks (2.3%).

• #1 Global study on rosacea: 5% of the population affected, according to Pierre Fabre Laboratories.

  https://www.pierre-fabre.com/en-us/press_release/global-study-on-rosacea-5-of-the-population-affected-according-to-pierre-fabre

  Spotlight on rosacea, which affects 5% of the world population according to the first global epidemiological study of this dermatosis carried out by Pierre Fabre Laboratories. […] Pierre Fabre Laboratories has unveiled the first global study on the epidemiology of rosacea, published in February 2024 in the prestigious Journal of the American Academy of Dermatology. […] The global prevalence of rosacea is 5%. […] Women are more affected by rosacea than men, at 5.9% versus 4.4%, respectively. […] Significant disparities were observed between geographic areas. The highest prevalence of rosacea was observed in East Asia (4%) and Latin America (3.5%), while the lowest prevalence was observed in Africa (1%) and North America (2.8%). […] 54% of people suffering from rosacea experience fatigue and 50% of them have difficulty sleeping.

• #1 Rosacea: Epidemiology, pathogenesis, and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5821167/

  Rosacea is a chronic relapsing inflammatory skin disease with a high prevalence among adults of Northern European heritage with fair skin. […] Caucasians with fair sun-sensitive skin (skin phototypes I and II) appear to have the greatest risk for rosacea. […] Estimates of the prevalence of rosacea in fair-skinned populations range from 2 to 22 percent. […] A recent prospective study from Germany reported an overall rosacea prevalence of 12 percent, with erythematotelangiectatic and papulopustular subtypes making up 9 and 3 percent, respectively. […] Prevalence rates for ocular involvement in rosacea patients range from less than 10 percent to more than 50 percent. […] Cutaneous rosacea exhibits a strong female predominance, with the exception of phymatous rosacea, and is usually diagnosed after the age of 30 years.

• #1 Global epidemiology and clinical spectrum of rosacea, highlighting skin of color: Review and clinical practice experience.

  https://vivo.weill.cornell.edu/display/pubid30240779

  Rosacea has been reported less frequently among individuals with skin of color than in those with white skin, but rosacea is not a rare disease in this population. In fact, rosacea might be underreported and underdiagnosed in populations with skin of color because of the difficulty of discerning erythema and telangiectasia in dark skin. […] The susceptibility of persons with highly pigmented skin to dermatologic conditions like rosacea, whose triggers include sun exposure, is probably underestimated. Many people with skin of color who have rosacea might experience delayed diagnosis, leading to inappropriate or inadequate treatment; greater morbidity; and uncontrolled, progressive disease with disfiguring manifestations, including phymatous rosacea. […] In this article, we review the epidemiology of rosacea in skin of color and highlight variations in the clinical presentation of rosacea across the diverse spectrum of patient populations affected. We present strategies to aid in the timely diagnosis and effective treatment of rosacea in patients with skin of color, with an aim of promoting increased awareness of rosacea in these patients and reducing disparities in the management of their disease.

• #1 Ocular Rosacea: Background, Pathophysiology, Epidemiology

  https://emedicine.medscape.com/article/1197341-overview

  Women are affected with the papulopustular and erythematotelangiectatic rosacea subtypes twice as often as men; however, the phymatous rosacea subtype develops much more frequently in men. […] Ocular rosacea affects both sexes equally. […] All ages can be affected, including pediatric patients. […] Peak incidence occurs in the fourth to seventh decades of life.

• #1 Surgical & Cosmetic Dermatology | Prospective study for the treatment of rosacea flushing with botulinum toxin type A

  http://www.surgicalcosmetic.org.br/details/634/en-US/prospective-study-for-the-treatment-of-rosacea-flushing-with-botulinum-toxin-type-a

  Rosacea is a chronic facial condition characterized by erythema, edema, telangiectasias, papules and possibly pustules and nodules. […] The prevalence of rosacea in the last few years varied between 1 and 22%, depending on the methodology used and the population analyzed. The most recent rates, obtained from retrospective study databases, range from 1.3% to 2.1%. […] It affects more women than men, and Subtype I is the most prevalent, followed by Subtype II. Phymatous rosacea is seen mainly in males of over 40 years of age. […] Taking all these factors into account, rosacea is a more common dermatological entity than previously suspected. […] The exact pathogenesis of rosacea is still unknown, however some factors are deemed relevant for its occurrence, such as: dysfunction in the innate immune system; exposure to ultraviolet radiation, which causes increased angiogenesis and the production of reactive oxygen species; vascular changes, increasing the expression of vascular endothelial growth factor and lymphatic endothelial markers; epidermal barrier dysfunction; neurogenic inflammation (sensory nerves release neuromediators at the site of inflammation resulting in vasodilation); recruitment of inflammatory cells; extravasation of plasma proteins; and microbial action – Demodex foliculorum and Demodex brevis, and intense perifollicular inflammatory infiltrate.

• #1 Rosacea Epidemiology and Genetics | SpringerLink

  https://link.springer.com/chapter/10.1007/978-3-319-49274-2_12

  Rosacea is a chronic inflammatory skin condition that affects approximately 16 million US Americans. Considering the prevalence of rosacea in a US community setting, 6% of individuals had rosacea. Older, white individuals with fairer skin types (Fitzpatrick skin types IIII) were more likely to have rosacea. The largest epidemiological study of rosacea, a British trial including 60,042 rosacea cases, reported an incidence rate of 1.65 per 1000 person-years. A German registry study with a cohort of 90,880 office employees exhibited a prevalence of 2.3%, while a Swedish study with 809 office employees revealed prevalence rates of 14% in women and 5% in men. An Estonian study with 348 employees, who were over 30 years old, exhibited a prevalence of 22%. According to a recent study, rosacea prevalence was 12.3% in Germany and 5.0% in Russia. In Tunisia, where photo skin types IV and V predominate, a hospital prevalence rate of 0.2% was reported. Whereas rosacea is diagnosed more frequently in Caucasians, the disease appears in Black, Asian, and Hispanic populations. Patients with colored skin rarely receive the diagnosis of rosacea, even when they have symptoms suggesting it. Ocular involvement is not uncommon and has been reported in the range of 358% of rosacea patients. Although rare, childhood rosacea should be recognized. Rosacea in childhood is more frequently associated with ocular involvement, which may represent the only manifestation of the disease in this age group.

• #1 Ocular Rosacea: Background, Pathophysiology, Epidemiology

  https://emedicine.medscape.com/article/1197341-overview

  More than 10% of the general population exhibits dermatologic characteristics of rosacea; of these, up to 60% experience ocular complications. […] An epidemiological study in Sweden showed a 10% prevalence of rosacea. […] A study in Estonia showed a 22% prevalence rate of rosacea, as determined by the American National Rosacea Society Expert Committee (NRSEC) classification. […] While rosacea is not a life-threatening disease, it is a source of much morbidity because of pruritus, burning, and psychosocial impairments. […] Approximately 5% of patients with rosacea manifest corneal disease, which can rarely be severe and lead to blindness via corneal ulceration, perforation, secondary infections, or corneal opacification from complete vascularization. […] Rosacea is recognized much more commonly in fair-skinned, white patients than in dark-skinned patients.

• #1 Rosacea – Knowledge @ AMBOSS

  https://www.amboss.com/us/knowledge/rosacea/

  Epidemiological data refers to the US, unless otherwise specified. […] Age range: : 3060 years [1][2] […] Ocular rosacea can occur with or without cutaneous features. […] Affects 50% of patients with typical cutaneous manifestations of rosacea [8][9] […] One-fifth of individuals with rosacea develop ocular features before cutaneous manifestations. [8]

• #1 Epidemiology of rosacea described in United Kingdom

  https://medicalxpress.com/news/2012-05-epidemiology-rosacea-kingdom.html

  Epidemiology of rosacea described in United Kingdom […] (HealthDay) — The incidence of rosacea in the United Kingdom is 1.65 per 1,000 person-years, with alcohol consumption linked to a modest increase in risk and current smoking linked to an decreased risk, according to a study published online May 5 in the British Journal of Dermatology. […] To quantify the incidence rates and describe the demographic characteristics of rosacea, Julia Spoendlin, from the University of Basel in Switzerland, and colleagues used the U.K.-based General Practice Research Database to identify 60,042 patients with a new diagnosis of rosacea between 1995 and 2009 and matched them to 60,042 rosacea-free control patients. […] The researchers found that, in the United Kingdom, the overall incidence rate for rosacea was 1.65 per 1,000 person-years. In 80 percent of cases, diagnosis occurred after the age of 30 years. In 20.8 percent of cases, ocular symptoms were noted at the index date. Current smokers had a significantly reduced relative risk of developing rosacea (odds ratio, 0.64), while there was a marginally increased risk seen for alcohol consumption.

• #1 Epidemiology of rosacea: updated data – EM consulte

  https://www.em-consulte.com/article/680652/epidemiology-of-rosacea-updated-data

  Les donnes pidmiologiques sur la rosace restent encore parcellaires et de qualit mthodologique discutable. La rosace touche principalement des adultes aprs lge de 30 ans et prdomine classiquement chez la femme. Des tudes rcentes estoniennes et irlandaises suggrent que la prdominance fminine nest peut-tre pas aussi importante quon le croyait. La prvalence augmente en tout cas avec lge. Les chiffres de prvalence publis en Europe et aux tats-Unis sont trs variables, allant de moins de 1% plus de 20% de la population adulte. En fait, les mthodes utilises et les populations tudies varient beaucoup dune tude lautre, ce qui ne permet pas de les comparer. […] […] Lexistence dantcdents familiaux est un facteur de risque, de mme que le phototype clair ( maldiction des Celtes ). Lalcool et le caf classiquement incrimins ne sont pas des facteurs de risqu ; le tabac pourrait au contraire avoir un effet protecteur . De nouveaux travaux sont sans aucun doute necessaries : ils devront alors utiliser les critres de diagnostic et de svrit tablis en 2002 et 2004. […]

• #1 Rosacea: MedlinePlus GeneticsLock

  https://medlineplus.gov/genetics/condition/rosacea/

  Rosacea is a common skin condition. Depending on the population studied and the criteria used to diagnose the disorder, estimates of disease prevalence range from less than 1 percent to more than 20 percent of the population. […] Rosacea is diagnosed most often in early to mid-adulthood. It is unknown how common the disease is in children because most studies have involved adults. For reasons that are unclear, women appear to be affected more often than men. […] Studies suggest that people with rosacea are four times more likely to have a family history of the disorder than people without the condition.

• #1 Rosacea: Diagnosis and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2015/0801/p187.html

  Rosacea is a chronic facial skin condition of unknown cause. The exact prevalence of rosacea in the United States is unknown; however, it is probably between 1.3% and 2.1%, and may be as high as 5%. Women are affected more often than men, but men are more likely to have phymatous changes, especially rhinophyma. […] In a national survey, 65% of patients with rosacea reported symptoms of depression. […] The National Rosacea Society Expert Committee defined four subtypes and one variant. […] A predilection for fair-skinned individuals of Celtic or northern European descent suggests a genetic component to rosacea. […] Numerous triggers initiate or aggravate the clinical manifestations of rosacea, including ultraviolet light, heat, spicy foods, and alcohol.

• #1 Dermatological Conditions in Skin of Color– Diagnosing and Treating Rosacea in Skin of Color Patients | JCAD – The Journal of Clinical and Aesthetic Dermatology

  https://jcadonline.com/diagnosing-treating-rosacea-skin-of-color/

  The worldwide prevalence of rosacea is estimated to be between 5.5 percent and 10 percent. It is a chronic, inflammatory skin disorder that is most commonly associated with fair-skinned patients. In Ireland, the incidence is estimated to be 14 percent, and in Germany, it is estimated to be 12 percent. The incidence rates in skin of color (SOC) patients are estimated to be much lower. Rosacea is thought to affect two percent of Black patients, 3.9 percent of Hispanic of Latino patients, and 2.3 percent of Asian/Pacific Islanders. The lower incidence rate of rosacea in SOC patients may be due to genetics and environmental factors, but it may also be due to a lower index of suspicion. At present time, there is no evidence to demonstrate if certain therapeutics respond better in SOC populations, thus it is recommended to follow the current management guidelines from the American Acne Rosacea Society. […] In a review by Morgado-Carrasco et al, ultraviolet (UV) light was found to impact skin inflammation, neoangiogenesis, telangiectasa/fibrosis, and may also initiate rosacea.

• #1 Deciphering Childhood Rosacea: A Comprehensive Review

  https://www.mdpi.com/2077-0383/13/4/1126

  Currently, the exact prevalence and incidence of childhood rosacea are not well known. A recent study by Hoepfner et al. reported that childhood rosacea was diagnosed in less than 1% of children in their single-center study. […] In a study identifying the hospital visit tendency of rosacea patients, 1.2% of the rosacea visits were observed among rosacea patients in their 20s or younger. […] An epidemiological study of rosacea conducted in the United Kingdom found that the incidence rate (IR) of rosacea in patients younger than 20 years old was 0.89 (95% confidence interval [CI]: 0.87–0.91) per 1000 person-years. […] Regarding the age of onset, some studies have reported that childhood rosacea occurred at an average age of 4 to 5 years. […] As for the sex, rosacea is most frequently observed in women in general.

• #1 Deciphering Childhood Rosacea: A Comprehensive Review

  https://www.mdpi.com/2077-0383/13/4/1126

  A study by Spoendlin et al. showed a slightly increased incidence rate in women (IR = 0.95; 95% CI: 0.92–0.98) compared to men (IR = 0.80; 95% CI: 0.80–0.86). In children, rosacea is similarly observed both in boys and girls. […] Although childhood rosacea can occur in all phototypes, the papulopustular type is more frequently observed in relatively light phototypes, and granulomatous rosacea occurs equally in patients with both dark and light skin.

• #1 Rosacea: Epidemiology, pathogenesis, and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5821167/

  Rosacea is considered a disease that is limited to the skin; however, there is accumulating evidence of significant associations between rosacea and systemic comorbidities. […] Population-based cohort studies confirmed these findings and reported further associations of rosacea and type 1 diabetes mellitus, celiac disease, multiple sclerosis, rheumatoid arthritis, Parkinson disease, and migraine. […] An increasing number of studies showed a relationship between rosacea and systemic comorbidities; however, the pathophysiologic connections remain to be defined.

• #1 Rosacea: Symptoms, Causes, and Management – DermNet

  https://dermnetnz.org/topics/rosacea

  Rosacea is estimated to affect around 5% of adults worldwide. […] Although rosacea can affect anyone, it is more common in those with fair skin, blue eyes, and those of Celtic or North European descent. […] It may be more difficult and under-recognised in patients with skin of colour. […] Rosacea has been associated with depression, hypertension, cardiovascular diseases, anxiety disorder, dyslipidemia, diabetes mellitus, migraine, rheumatoid arthritis, Helicobacter pylori infection, ulcerative colitis, and dementia. […] Rosacea is diagnosed more frequently in fair-skinned patients of Celtic and Northern European descent. […] It may be harder to identify key features of rosacea in patients with skin of colour. These features are likely under-recognised and rosacea may be underdiagnosed in these patients.

• #1 Rosacea is strongly associated with melanoma in Caucasians | Scientific Reports

  https://www.nature.com/articles/s41598-024-62552-8

  Rosacea is often considered a cosmetic problem but is known to be associated with a variety of comorbidities. […] In contrast to earlier studies, we found significant associations with malignant melanoma (OR 6.02, 95% CI 5.766.32). […] Several strongly associated comorbidities like visual disturbances (ICD-10: H53H54; OR 4.80, 4.684.92), metabolic disorders (E73E79; OR 3.17, 3.113.22), joint problems (M25; OR 4.16, 4.084.25) and type 2 diabetes (E11; OR 1.62, 1.581.65) should be watched as a risk for rosacea patients. […] Rosacea is associated with some comorbidities and ethnicity may be a risk factor in melanoma development. […] The aim of this study was to use data from the real-world database TriNetX to investigate a possible correlation between rosacea and systemic diseases on a global level and to explore potential associations of rosacea and malignant melanoma.

• #1 Epidemiology of rosacea: updated data – EM consulte

  https://www.em-consulte.com/article/680652/epidemiology-of-rosacea-updated-data

  La rosace a un fort impact sur la qualit de vie et peut sassocier des symptmes dpressifs. Une chelle de qualit de vie spcifique, RosaQol a t construite et valide aux tats-Unis, par le mme groupe qui a labor lchelle Skindex. Des traductions de cette chelle en franais, italien, allemand et espagnol ont t valides ce qui pourrait permettre lavenir des comparaisons interculturelles.

• #1 Burden of Disease: The Psychosocial Impact of Rosacea on a Patient’s Quality of Life

  https://www.ahdbonline.com/articles/1484-feature-1484

  The impact of rosacea on the patients emotional health and quality of life has been underestimated or overlooked. Surveys conducted by the National Rosacea Society and by Kelton Research have indicated that people have a negative impression of patients with rosacea. […] Patients with rosacea are affected by emotional and social stigmas, including being viewed as abusers of alcohol or as having poor hygiene. […] The visible facial erythema and blemishes that are associated with rosacea can negatively affect patients emotional health. The improvement of the clinical symptoms of rosacea improves the patients emotional well-being. Current therapies treat the papules and pustules that are associated with rosacea, but no approved therapies target persistent facial erythema. […] New therapies currently in development may be able to treat the broad range of symptoms of rosacea.

• #1 Global study on rosacea: 5% of the population affected, according to Pierre Fabre Laboratories.

  https://www.pierre-fabre.com/en-us/press_release/global-study-on-rosacea-5-of-the-population-affected-according-to-pierre-fabre

  People suffering from rosacea reported feeling excluded or rejected by others (33%), and having the feeling that people avoid touching them (27%) or coming close to them (28%). […] A study entitled Patients’ testimonies, feelings, complaints and emotional experiences with dermatoses on open social media: The French infodemiologic patient’s free speech study, published in JEADV in January 2024, confirms significant stigmatization by presenting the difficulties expressed by patients with visible dermatoses on social networks.

• #1 Burden of Disease: The Psychosocial Impact of Rosacea on a Patient’s Quality of Life

  https://www.ahdbonline.com/issues/2013/july-august-2013-vol-6-no-6/feature-1484

  Rosacea is more prevalent in fair-skinned people of Northern European and Eastern European descent, but it has also been reported in people of other ethnicities. Women are more frequently affected than men, with onset of this condition generally occurring between the ages of 30 and 50 years, although rosacea has been reported in the teenaged years. […] A National Rosacea Society survey of 600 patients with rosacea showed that nearly 52% of survey respondents also had a family member with the disease, and 42% reported that they were of Irish, German, or English descent. […] Rosacea affects more than 16 million people in the United States. Between 1990 and 1997, there were approximately 1.1 million outpatient visits, annually, for rosacea in the United States. […] Based on data compiled by Galderma Laboratories, LP, on office visits for rosacea, between October 2011 and September 2012 there were 1.67 million office visits in the United States, with 75% of the visits conducted with dermatologists.

• #1 Rosacea in skin of color: A comprehensive review – Indian Journal of Dermatology, Venereology and Leprology

  https://ijdvl.com/rosacea-in-skin-of-color-a-comprehensive-review/

  Rosacea is reported less commonly in the skin of color, probably because darker skin types are less prone to photodamage and additionally flushing and telangiectasia are harder to detect clinically. However, many recent studies from this part of the world including India have detected its rising prevalence in recent times, although this condition remains to be underreported. […] Rosacea remains an underreported condition in the skin of color, although its prevalence is more than what was thought previously. Epidemiological studies, especially from India are scarce and there is a need to identify clinical markers with better sensitivity to improve the diagnosis of rosacea in patients with skin of color.

• #1 Patient-focused Solutions in Rosacea Management: Treatment Challenges in Special Patient Groups – JDDonline – Journal of Drugs in Dermatology

  https://jddonline.com/articles/patient-focused-solutions-in-rosacea-management-treatment-challenges-in-special-patient-groups-S1545961619P0608X/?_page=5

  Rosacea is a chronic inflammatory skin condition due to immune and neurovascular dysfunction that has significant effects on QOL. […] Though more prevalent in patients with fair skin, rosacea occurs in people of all races and ethnicities and until recently has been largely under recognized in nonwhite populations. […] In order to optimize treatment of rosacea, recognizing more subtle or less typical features in special patient groups is essential. […] Future studies should continue to evaluate efficacy in diverse populations to accurately reflect the patients in need of treatment.

• #1

  https://journals.lww.com/tjod/fulltext/2020/14020/assessment_of_acne_rosacea_prevalence_and_quality.4.aspx

  The aim of this study was to determine the prevalence of acne rosacea among adults, examine some related variables and evaluate the quality of life. […] The prevalence of acne rosacea was 22.6% (n = 504). […] There is no community-based prevalence study with AR patients in Turkey population. For this reason, the aim of this study was to determine the prevalence of AR among adults living in Mahmudiye district center, to examine some variables thought to be related with AR, and to evaluate the quality of life. […] In our study, the AR prevalence was found to be 22.6%. […] The AR prevalence has been reported as 22% in Estonia, 12.3% in Germany, 11% in the USA, 10% in Sweden, and 5% in Russia. […] The AR prevalence increased as the age progressed. […] One of the risk factors for AR in our study was the presence of familial AR history. […] Participants with acne rosacea had low quality of life based on the physical function subscale. […] It may be useful to perform intermittent screening for early diagnosis and treatment, directing the suspected cases to a specialist physician, and conducting informative studies to raise awareness.

• #1 Rosacea: Symptoms, Causes, and Management – DermNet

  https://dermnetnz.org/topics/rosacea

  Rosacea is diagnosed clinically in the majority of cases. Diagnosis is made according to diagnostic and major criteria recommended by the 2017 global ROSacea COnsensus (ROSCO) panel. This requires one diagnostic criterion or two major criteria to be fulfilled. […] In patients with darker phototypes where erythema and telangiectasia (visible blood vessels) is more difficult to visualise, greater emphasis may be placed on other major and minor features. […] Although there is no cure for rosacea, symptoms can be managed with the following lifestyle measures, medical, and procedural interventions. […] Although rosacea is not a life-threatening condition, it is a chronic disease that requires long-term management of relapsing and remitting symptoms.

• #2 Global study on rosacea: 5% of the population affected, according to Pierre Fabre Laboratories.

  https://www.pierre-fabre.com/en-us/press_release/global-study-on-rosacea-5-of-the-population-affected-according-to-pierre-fabre

  Spotlight on rosacea, which affects 5% of the world population according to the first global epidemiological study of this dermatosis carried out by Pierre Fabre Laboratories. […] Pierre Fabre Laboratories has unveiled the first global study on the epidemiology of rosacea, published in February 2024 in the prestigious Journal of the American Academy of Dermatology. […] The global prevalence of rosacea is 5%. […] Women are more affected by rosacea than men, at 5.9% versus 4.4%, respectively. […] Significant disparities were observed between geographic areas. The highest prevalence of rosacea was observed in East Asia (4%) and Latin America (3.5%), while the lowest prevalence was observed in Africa (1%) and North America (2.8%). […] 54% of people suffering from rosacea experience fatigue and 50% of them have difficulty sleeping.

• #2

  https://link.springer.com/article/10.1007/s13671-014-0070-5

  Rosacea is a chronic, inflammatory skin disease that affects more than 15 million people in the United States. It is associated with significant psychosocial, physical, and economic burden. […] Epidemiologic aspects of rosacea. J Am Acad Dermatol. 2005;53(5):9189. […] A study on the epidemiology of rosacea in the U.K. Br J Dermatol. 2012;167(3):598605. […] Rosacea: Current state of epidemiology. J Am Acad Dermatol. 2013;69(6 Suppl 1):S2735. This manuscript reviews the major epidemiologic data of rosacea.

• #2 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Rosacea-Epidemiology.aspx

  Rosacea is a common but under-diagnosed condition of the facial skin that affects around 10% of all individuals. […] In the United States, the prevalence of rosacea seems to be on the rise and in the United Kingdom, the prevalence is 1.65 per 1000 person-years. […] There is a paucity of epidemiological data on rosacea, with reported prevalence rates ranging from as little as 0.09% to as much as 22.00%. […] The condition is most common among individuals aged 30 to 50 years and women are two to three times more likely to be affected than men, with women of menopausal age at a greater risk still. […] The condition often goes undiagnosed among dark-skinned individuals who may have a different clinical presentation to fair-skinned people and suffer more from complications such as conjunctivitis and blepharitis (eyelid swelling). […] In one study examining the prevalence of rosacea subtypes, 14.8 % of women had type 1 or erythematotelangiectatic rosacea while only 1.5% had the second type, papulopustular rosacea.

• #2 Ocular Rosacea: Background, Pathophysiology, Epidemiology

  https://emedicine.medscape.com/article/1197341-overview

  More than 10% of the general population exhibits dermatologic characteristics of rosacea; of these, up to 60% experience ocular complications. […] An epidemiological study in Sweden showed a 10% prevalence of rosacea. […] A study in Estonia showed a 22% prevalence rate of rosacea, as determined by the American National Rosacea Society Expert Committee (NRSEC) classification. […] While rosacea is not a life-threatening disease, it is a source of much morbidity because of pruritus, burning, and psychosocial impairments. […] Approximately 5% of patients with rosacea manifest corneal disease, which can rarely be severe and lead to blindness via corneal ulceration, perforation, secondary infections, or corneal opacification from complete vascularization. […] Rosacea is recognized much more commonly in fair-skinned, white patients than in dark-skinned patients.

• #2 Epidemiology of rosacea described in United Kingdom

  https://medicalxpress.com/news/2012-05-epidemiology-rosacea-kingdom.html

  Epidemiology of rosacea described in United Kingdom […] (HealthDay) — The incidence of rosacea in the United Kingdom is 1.65 per 1,000 person-years, with alcohol consumption linked to a modest increase in risk and current smoking linked to an decreased risk, according to a study published online May 5 in the British Journal of Dermatology. […] To quantify the incidence rates and describe the demographic characteristics of rosacea, Julia Spoendlin, from the University of Basel in Switzerland, and colleagues used the U.K.-based General Practice Research Database to identify 60,042 patients with a new diagnosis of rosacea between 1995 and 2009 and matched them to 60,042 rosacea-free control patients. […] The researchers found that, in the United Kingdom, the overall incidence rate for rosacea was 1.65 per 1,000 person-years. In 80 percent of cases, diagnosis occurred after the age of 30 years. In 20.8 percent of cases, ocular symptoms were noted at the index date. Current smokers had a significantly reduced relative risk of developing rosacea (odds ratio, 0.64), while there was a marginally increased risk seen for alcohol consumption.

• #2 Rosacea: Diagnosis and Treatment | AAFP

  https://www.aafp.org/pubs/afp/issues/2015/0801/p187.html

  Rosacea is a chronic facial skin condition of unknown cause. The exact prevalence of rosacea in the United States is unknown; however, it is probably between 1.3% and 2.1%, and may be as high as 5%. Women are affected more often than men, but men are more likely to have phymatous changes, especially rhinophyma. […] In a national survey, 65% of patients with rosacea reported symptoms of depression. […] The National Rosacea Society Expert Committee defined four subtypes and one variant. […] A predilection for fair-skinned individuals of Celtic or northern European descent suggests a genetic component to rosacea. […] Numerous triggers initiate or aggravate the clinical manifestations of rosacea, including ultraviolet light, heat, spicy foods, and alcohol.

• #2 Rosacea is strongly associated with melanoma in Caucasians | Scientific Reports

  https://www.nature.com/articles/s41598-024-62552-8

  Rosacea is often considered a cosmetic problem but is known to be associated with a variety of comorbidities. […] In contrast to earlier studies, we found significant associations with malignant melanoma (OR 6.02, 95% CI 5.766.32). […] Several strongly associated comorbidities like visual disturbances (ICD-10: H53H54; OR 4.80, 4.684.92), metabolic disorders (E73E79; OR 3.17, 3.113.22), joint problems (M25; OR 4.16, 4.084.25) and type 2 diabetes (E11; OR 1.62, 1.581.65) should be watched as a risk for rosacea patients. […] Rosacea is associated with some comorbidities and ethnicity may be a risk factor in melanoma development. […] The aim of this study was to use data from the real-world database TriNetX to investigate a possible correlation between rosacea and systemic diseases on a global level and to explore potential associations of rosacea and malignant melanoma.

• #2 Ocular Rosacea: Background, Pathophysiology, Epidemiology

  https://emedicine.medscape.com/article/1197341-overview

  Women are affected with the papulopustular and erythematotelangiectatic rosacea subtypes twice as often as men; however, the phymatous rosacea subtype develops much more frequently in men. […] Ocular rosacea affects both sexes equally. […] All ages can be affected, including pediatric patients. […] Peak incidence occurs in the fourth to seventh decades of life.

• #2 New Study Estimates Rosacea’s Worldwide Prevalence | Rosacea.org

  https://www.rosacea.org/blog/2024/may/new-study-estimates-rosaceas-worldwide-prevalence

  A new study on the global epidemiology of rosacea and acne offers a new estimate of how many people may have rosacea worldwide. The study, which was conducted on 50,552 individuals older than 16 from 20 countries that comprise more than half of the worlds population, found an overall rosacea prevalence of 5.1%. An earlier study that pooled data from 32 population-based studies comprising 26.5 million people found a similar prevalence of 5.46%, though those researchers noted that the proportions in individual studies varied widely and were higher when rosacea was self-reported. […] Whereas past studies and NRS surveys have indicated that fair-skinned individuals with a northern European background were more prone to developing the disorder, the new study reported the greatest prevalence in East Asia (4%), followed by Latin America (3.5%), the Middle East (3.4%), Australia (3.2%) and then Europe (3.1%). The researchers also found that people of mixed ethnicity showed the highest prevalence of rosacea (4.3%), followed by whites (3.3%), Asians (3.1%) and Blacks (2.3%).

• #2 New Studies Show High Incidence of Rosacea and Possible New Causes | Rosacea.org

  https://www.rosacea.org/rosacea-review/2007/summer/new-studies-show-high-incidence-of-rosacea-and-possible-new-causes

  As expected, subtype 1 (erythematotelangiectatic) rosacea, characterized by facial redness, was the most prevalent form of the disorder. […] It was found in 14.8 percent of the Caucasian women in the new study, compared to 1.5 percent with subtype 2 (papulopustular) rosacea, which includes bumps and pimples. […] The researchers studied women from Los Angeles, Rome, London and Akita, Japan. […] Rosacea was especially prevalent in the English group, at more than 20 percent, although the incidence of subtype 2 was somewhat higher among the American women. […] In an ongoing NRS-funded study in Ireland, Dr. Maeve McAleer of the Regional Centre of Dermatology, Mater Misericordiae University Hospital, Dublin, noted that subtype 2 rosacea was found present in 2.6 percent of 400 subjects from among hospital workers and 2.9 percent from Aran Island inhabitants.

• #2 Rosacea: Epidemiology, pathogenesis, and treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC5821167/

  Rosacea is a chronic relapsing inflammatory skin disease with a high prevalence among adults of Northern European heritage with fair skin. […] Caucasians with fair sun-sensitive skin (skin phototypes I and II) appear to have the greatest risk for rosacea. […] Estimates of the prevalence of rosacea in fair-skinned populations range from 2 to 22 percent. […] A recent prospective study from Germany reported an overall rosacea prevalence of 12 percent, with erythematotelangiectatic and papulopustular subtypes making up 9 and 3 percent, respectively. […] Prevalence rates for ocular involvement in rosacea patients range from less than 10 percent to more than 50 percent. […] Cutaneous rosacea exhibits a strong female predominance, with the exception of phymatous rosacea, and is usually diagnosed after the age of 30 years.

• #3

  https://journals.lww.com/tjod/fulltext/2020/14020/assessment_of_acne_rosacea_prevalence_and_quality.4.aspx

  The aim of this study was to determine the prevalence of acne rosacea among adults, examine some related variables and evaluate the quality of life. […] The prevalence of acne rosacea was 22.6% (n = 504). […] There is no community-based prevalence study with AR patients in Turkey population. For this reason, the aim of this study was to determine the prevalence of AR among adults living in Mahmudiye district center, to examine some variables thought to be related with AR, and to evaluate the quality of life. […] In our study, the AR prevalence was found to be 22.6%. […] The AR prevalence has been reported as 22% in Estonia, 12.3% in Germany, 11% in the USA, 10% in Sweden, and 5% in Russia. […] The AR prevalence increased as the age progressed. […] One of the risk factors for AR in our study was the presence of familial AR history. […] Participants with acne rosacea had low quality of life based on the physical function subscale. […] It may be useful to perform intermittent screening for early diagnosis and treatment, directing the suspected cases to a specialist physician, and conducting informative studies to raise awareness.

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