Materiały źródłowe

• #1 Dementia: What It Is, Causes, Symptoms, Treatment & TypesWhat It Is, Causes, Symptoms, Treatment & Types

  https://my.clevelandclinic.org/health/diseases/9170-dementia

  Vascular dementia: This is the second most common type of dementia. Its caused by conditions such as strokes or atherosclerosis, which block and damage blood vessels in your brain. Symptoms include memory problems, confusion and trouble concentrating and completing tasks. The decline may appear suddenly (following a major stroke) or in steps (following a series of mini strokes). Risk factors include high blood pressure, diabetes and high cholesterol levels. About 15% to 25% of people with dementia have vascular dementia. […] Dementias that arent reversible may still partially respond to medications that treat memory loss or behavior problems. These dementias include: […] Multi-infarct (vascular) dementia. […] Drugs approved for the most common form of dementia, Alzheimers disease, include:

• #2 What Is Vascular Dementia?

  https://www.alzheimers.gov/alzheimers-dementias/vascular-dementia

  How Is Vascular Dementia Diagnosed and Treated? […] No treatments are available to reverse brain damage that has been caused by a stroke. Treatment for vascular dementia focuses on preventing future strokes. Medications to prevent strokes, such as blood thinners, may help decrease the risk of further damage to the brain. Medications that help treat the symptoms of Alzheimer’s disease might benefit people with early vascular dementia. A doctor may also recommend treating risk factors, such as high blood pressure or high cholesterol, through medications and lifestyle changes.

• #3 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Vascular dementia is a common condition for which there are no effective approved pharmacological treatments available. […] Despite all of the recent investment in experimental and clinical neuroscience, there are no effective pharmacological compounds approved for treatment of vascular dementia in any jurisdiction worldwide. […] Treatment of vascular dementia has also received extensive coverage. […] The prevailing conclusion of these reports is that most vascular dementia trials have produced disappointing results. It is important to note that so far no drug has been approved by regulatory agencies to treat vascular dementia. […] Memantine, an NMDA receptor antagonist, has a positive effect on cognition in patients with vascular dementia. […] Galantamine seems to improve working memory in vascular dementia patients, but it does not have a clearly documented clinical benefit in vascular dementia.

• #4 Vascular Dementia

  https://www.uspharmacist.com/article/vascular-dementia

  There are no FDA-approved drugs for the treatment of VaD. However, the use of cholinesterase inhibitors and N-methyl-d-aspartate receptor antagonists for VaD has been evaluated. […] Importantly, the scales used to measure clinical significance in these trials were developed for AD. […] Current data do not warrant the widespread use of cholinesterase inhibitors or memantine for VaD; for now, clinical judgment must guide individual treatment decisions. […] Once VaD or VCI has been diagnosed, attention should be directed at prevention and modification of risk factors. […] It is hoped that lowering cholesterol reduces VCI risk. […] Aspirin and other antiplatelet therapies are effective for stroke prevention. […] The American Heart Association/American Stroke Association and American College of Chest Physicians’ recommendations for secondary prevention of stroke should be followed until more data on antiplatelet agents for treating VaD are available. […] Cholinesterase inhibitors and memantine may be options for some patients; their use should be judicious, with attention paid to achieving therapeutic doses according to manufacturers’ schedules.

• #5

  https://www.nhs.uk/conditions/vascular-dementia/treatment/

  Treatment can help prevent further damage to the brain in people with vascular dementia and may slow down its progression. […] But there’s currently no cure for the condition or a way to reverse the damage that’s already happened. […] The main aim of treatment for vascular dementia is to treat the underlying cause to help stop the condition getting worse. […] Medicines may also be offered to treat the underlying cause of vascular dementia and help stop it getting worse. […] An antipsychotic medicine, such as haloperidol or risperidone, may sometimes be given to people showing persistent aggression or extreme distress where there’s a risk of harm to themselves or others. […] Alzheimer’s disease medicines, such as donepezil (Aricept), galantamine (Reminyl), rivastigmine (Exelon) or memantine are not used to treat vascular dementia, but may be used in people who have a combination of vascular dementia and Alzheimer’s disease. […] There are also several therapies and practical measures that can help make everyday living easier for someone with dementia. […] It can also be helpful to get in touch with a support group, such as the Alzheimer’s Society or Dementia UK.

• #6

  https://www.nhs.uk/conditions/vascular-dementia/treatment/

  Treatment can help prevent further damage to the brain in people with vascular dementia and may slow down its progression. […] But there’s currently no cure for the condition or a way to reverse the damage that’s already happened. […] The main aim of treatment for vascular dementia is to treat the underlying cause to help stop the condition getting worse. […] Medicines may also be offered to treat the underlying cause of vascular dementia and help stop it getting worse. […] An antipsychotic medicine, such as haloperidol or risperidone, may sometimes be given to people showing persistent aggression or extreme distress where there’s a risk of harm to themselves or others. […] Alzheimer’s disease medicines, such as donepezil (Aricept), galantamine (Reminyl), rivastigmine (Exelon) or memantine are not used to treat vascular dementia, but may be used in people who have a combination of vascular dementia and Alzheimer’s disease. […] There are also several therapies and practical measures that can help make everyday living easier for someone with dementia. […] It can also be helpful to get in touch with a support group, such as the Alzheimer’s Society or Dementia UK.

• #7 Vascular dementia – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/vascular-dementia/diagnosis-treatment/drc-20378798

  Treatment often focuses on managing the health conditions and risk factors that contribute to vascular dementia. […] Controlling conditions that affect the underlying health of your heart and blood vessels can sometimes slow the rate at which vascular dementia gets worse, and may also sometimes prevent further decline. Depending on your individual situation, your doctor may prescribe medications to: […] Lower your blood pressure […] Reduce your cholesterol level […] Prevent your blood from clotting and keep your arteries clear […] Help control your blood sugar if you have diabetes.

• #8 Vascular dementia – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/vascular-dementia/diagnosis-treatment/drc-20378798

  Treatment often focuses on managing the health conditions and risk factors that contribute to vascular dementia. […] Controlling conditions that affect the underlying health of your heart and blood vessels can sometimes slow the rate at which vascular dementia gets worse, and may also sometimes prevent further decline. Depending on your individual situation, your doctor may prescribe medications to: […] Lower your blood pressure […] Reduce your cholesterol level […] Prevent your blood from clotting and keep your arteries clear […] Help control your blood sugar if you have diabetes.

• #9 Vascular Dementia Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/292105-treatment

  Regular follow-up every 46 months is recommended to assess the patient’s general condition and cognitive and noncognitive symptoms. […] Treatment of risk factors such as hypertension, hypercholesterolemia, and diabetes mellitus require special attention. […] The mainstay of management of vascular dementia is the prevention of new strokes. This includes administering antiplatelet drugs and controlling major vascular risk factors. Aspirin has also been found to slow the progression of vascular dementia. […] Drug treatment is primarily used to prevent further worsening of vascular dementia by treating the underlying disease such as hypertension, hyperlipidemia, and diabetes mellitus. Antiplatelet agents are indicated. […] Pentoxifylline and, to a more limited extent, ergoloid mesylates (Hydergine), may be useful for increasing cerebral blood flow.

• #10 Vascular dementia – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/vascular-dementia/diagnosis-treatment/drc-20378798

  Treatment often focuses on managing the health conditions and risk factors that contribute to vascular dementia. […] Controlling conditions that affect the underlying health of your heart and blood vessels can sometimes slow the rate at which vascular dementia gets worse, and may also sometimes prevent further decline. Depending on your individual situation, your doctor may prescribe medications to: […] Lower your blood pressure […] Reduce your cholesterol level […] Prevent your blood from clotting and keep your arteries clear […] Help control your blood sugar if you have diabetes.

• #11 Treating vascular dementia | informedhealth.org

  https://www.informedhealth.org/treating-vascular-dementia.html

  Antiplatelets can lower the risk of blood clots causing damage to the blood vessels in the brain. […] People who have diabetes have an increased risk of stroke. […] In Germany, drugs for Alzheimers (anti-dementia drugs) haven’t been approved for the treatment of vascular dementia. […] There is some weak evidence that high doses of Ginkgo biloba extract can improve a persons ability to think clearly for some time. […] If the dementia has an effect on somebodys personality and behavior, both medication and non-medication treatment options are possible. […] The aim is to help them understand the disease better and cope with it in day-to-day life.

• #12 Vascular Dementia Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/292105-treatment

  Regular follow-up every 46 months is recommended to assess the patient’s general condition and cognitive and noncognitive symptoms. […] Treatment of risk factors such as hypertension, hypercholesterolemia, and diabetes mellitus require special attention. […] The mainstay of management of vascular dementia is the prevention of new strokes. This includes administering antiplatelet drugs and controlling major vascular risk factors. Aspirin has also been found to slow the progression of vascular dementia. […] Drug treatment is primarily used to prevent further worsening of vascular dementia by treating the underlying disease such as hypertension, hyperlipidemia, and diabetes mellitus. Antiplatelet agents are indicated. […] Pentoxifylline and, to a more limited extent, ergoloid mesylates (Hydergine), may be useful for increasing cerebral blood flow.

• #13 Vascular dementia – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/vascular-dementia/diagnosis-treatment/drc-20378798

  Treatment often focuses on managing the health conditions and risk factors that contribute to vascular dementia. […] Controlling conditions that affect the underlying health of your heart and blood vessels can sometimes slow the rate at which vascular dementia gets worse, and may also sometimes prevent further decline. Depending on your individual situation, your doctor may prescribe medications to: […] Lower your blood pressure […] Reduce your cholesterol level […] Prevent your blood from clotting and keep your arteries clear […] Help control your blood sugar if you have diabetes.

• #14 Vascular Dementia Treatment | BrainTest

  https://braintest.com/vascular-dementia-treatment/

  The medication youll be prescribed will depend on the underlying condition youre suffering from. […] Both donepezil and galantamine are commonly prescribed for individuals suffering from Alzheimers and can be used in cases of vascular dementia as well. […] If you suffer from diabetes and you have not been managing your blood sugar properly, you could experience cognitive impairment. […] For those who are at risk of blood clots, drugs such as warfarin, a common anticoagulant, may be prescribed to reduce ones risk of a second stroke. […] Once damage has occurred and symptoms have developed, there are some supportive measures you can take in order to improve your condition. These treatment options are intended to make your life easier and improve your overall quality of life.

• #15 Vascular Dementia | Types of Dementia | UPMC Senior Services

  https://www.upmc.com/services/seniors/resources-for-caregivers/dementia/vascular-dementia

  There’s no cure for vascular dementia. Any destruction of brain cells is permanent. […] Treatment aims at the underlying cause of vascular dementia. At best, treatment can slow down the progression of the disease. […] Medicine to treat high blood pressure, cholesterol, and diabetes may help slow down brain cell damage. […] Doctors may prescribe aspirin or blood thinners to reduce the chances of blood clots. […] Preventing having another stroke may help slow down the progression of vascular dementia. […] Occupational and physical therapy may help manage the symptoms of vascular dementia. They can also help you stay active and mobile as long as possible.

• #16 Vascular dementia – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/vascular-dementia/diagnosis-treatment/drc-20378798

  Treatment often focuses on managing the health conditions and risk factors that contribute to vascular dementia. […] Controlling conditions that affect the underlying health of your heart and blood vessels can sometimes slow the rate at which vascular dementia gets worse, and may also sometimes prevent further decline. Depending on your individual situation, your doctor may prescribe medications to: […] Lower your blood pressure […] Reduce your cholesterol level […] Prevent your blood from clotting and keep your arteries clear […] Help control your blood sugar if you have diabetes.

• #17 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Mixed-Dementia-Prevention-and-Treatment.aspx

  In case of vascular dementia, physicians generally prescribe medicines that reduce blood pressure and cholesterol level, control blood glucose level, and prevent blood clotting. […] Although there is no particular cure for mixed dementia, health professionals often consider treating the single type of dementia which is diagnosed as a coexisting factor in mixed dementia. […] Treatment strategies are primarily designed to reduce the intensity of symptoms.

• #18 Treatment of vascular cognitive impairment and dementia – UpToDate

  https://www.uptodate.com/contents/treatment-of-vascular-cognitive-impairment-and-dementia

  Treatment of vascular cognitive impairment and dementia […] Vascular dementia (VaD) refers to any dementia that is primarily caused by cerebrovascular disease or impaired cerebral blood flow and falls within the spectrum of vascular cognitive impairment, a syndrome that includes all cognitive disorders in which cerebrovascular disease or impaired cerebral blood flow is a contributing causative factor. […] This topic will review the treatment and prognosis of VaD. […] Risk factor management — Patients with cognitive impairment and clinical or radiologic evidence of cerebrovascular pathology should be screened and treated for vascular risk factors, especially hypertension. […] In general, for patients with VaD, we follow the recommendations for secondary stroke prevention, which are described in detail separately.

• #19 Vascular dementia – Symptoms, diagnosis and treatment | BMJ Best Practice

  https://bestpractice.bmj.com/topics/en-gb/319

  Vascular dementia is characterised by a chronic progressive multifaceted impairment of cognitive function. […] Early aggressive treatment of vascular risk factors is suggested in order to prevent further cerebrovascular disease. Supportive care and management of behavioural and psychological symptoms are also important. Treatments aimed at improving cognitive symptoms have shown no clear benefit.

• #20 Vascular Dementia | Symptoms & Treatments | alz.org

  https://www.alz.org/alzheimers-dementia/what-is-dementia/types-of-dementia/vascular-dementia

  Vascular dementia is a decline in thinking skills caused by conditions that block or reduce blood flow to various regions of the brain, depriving them of oxygen and nutrients. […] The U.S. Food and Drug Administration (FDA) has not approved any drugs specifically to treat symptoms of vascular dementia, but there is evidence from clinical trials that drugs approved to treat Alzheimer’s symptoms may also offer a modest benefit in people with vascular dementia. Treatment primarily works to prevent the worsening of vascular dementia by treating the underlying disease, such as hypertension, hyperlipidemia or diabetes mellitus. Controlling risk factors that may increase the likelihood of further damage to the brain’s blood vessels is an important treatment strategy. […] Individuals should work with their physicians to develop the best treatment plan for their symptoms and circumstances.

• #21 Medicines to treat people with vascular dementia and other vascular cognitive impairments | Cochrane

  https://www.cochrane.org/CD013306/DEMENTIA_medicines-treat-people-vascular-dementia-and-other-vascular-cognitive-impairments

  What is the evidence for cholinesterase inhibitors (medicines designed to improve memory and thinking in people with dementia), when used with people who have vascular dementia? […] In this review, we evaluated three drugs from the cholinesterase inhibitor family, donepezil, rivastigmine, and galantamine. These medications are widely used in Alzheimer’s dementia but may also be useful in people with vascular dementia. […] We wanted to learn whether cholinesterase inhibitors benefit people with vascular dementia. We were interested in their effects on memory, thinking, and daily functioning. […] We found moderate- to high-certainty evidence that donepezil 5 mg, donepezil 10 mg, and galantamine have a slight beneficial effect on cognition in people with VCI, although the size of the change is unlikely to be clinically important.

• #22 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Donepezil had a beneficial effect on cognitive function, global assessment, and activities of daily living. […] Rivastigmine’s efficacy in vascular dementia has been studied insufficiently to draw any meaningful conclusions. […] Hydergine had statistically significant benefits on global measures in an apparent dose-dependent manner. […] Nicergoline may have a beneficial effect in vascular dementia but further studies with patients diagnosed using modern day diagnostic criteria are needed to confirm these findings. […] Nimodipine studies suggest that voltage-dependent Ca2+ channels play a limited, if any, role in pathogenesis of vascular dementia related symptoms and voltage-dependent Ca2+ channel antagonists such as nimodipine are not likely to be useful in their treatment. […] CDP-choline results in a modest but statistically significant improvement in memory, behavior and global function.

• #23 Medicines to treat people with vascular dementia and other vascular cognitive impairments | Cochrane

  https://www.cochrane.org/CD013306/DEMENTIA_medicines-treat-people-vascular-dementia-and-other-vascular-cognitive-impairments

  The data suggest that donepezil 10 mg has the greatest effect on cognition, but at the cost of adverse effects. […] Further research into rivastigmine is needed, including the use of transdermal patches. […] To assess the efficacy and safety of cholinesterase inhibitors in the treatment of adults with vascular dementia and other VCI. […] The trials included participants with possible or probable vascular dementia or cognitive impairment following stroke. […] For cognition, the results showed that donepezil 5 mg improves cognition slightly, although the size of the effect is unlikely to be clinically important. […] Donepezil 10 mg (MD 2.21 ADAS-Cog points, 95% CI 3.07 to 1.35; moderate-certainty evidence) and galantamine 16 to 24 mg (MD 2.01 ADAS-Cog point, 95%CI 3.18 to 0.85; moderate-certainty evidence) probably also improve cognition, although the larger effect estimates still may not be clinically important.

• #24 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Vascular dementia is a common condition for which there are no effective approved pharmacological treatments available. […] Despite all of the recent investment in experimental and clinical neuroscience, there are no effective pharmacological compounds approved for treatment of vascular dementia in any jurisdiction worldwide. […] Treatment of vascular dementia has also received extensive coverage. […] The prevailing conclusion of these reports is that most vascular dementia trials have produced disappointing results. It is important to note that so far no drug has been approved by regulatory agencies to treat vascular dementia. […] Memantine, an NMDA receptor antagonist, has a positive effect on cognition in patients with vascular dementia. […] Galantamine seems to improve working memory in vascular dementia patients, but it does not have a clearly documented clinical benefit in vascular dementia.

• #25 Medicines to treat people with vascular dementia and other vascular cognitive impairments | Cochrane

  https://www.cochrane.org/CD013306/DEMENTIA_medicines-treat-people-vascular-dementia-and-other-vascular-cognitive-impairments

  The data suggest that donepezil 10 mg has the greatest effect on cognition, but at the cost of adverse effects. […] Further research into rivastigmine is needed, including the use of transdermal patches. […] To assess the efficacy and safety of cholinesterase inhibitors in the treatment of adults with vascular dementia and other VCI. […] The trials included participants with possible or probable vascular dementia or cognitive impairment following stroke. […] For cognition, the results showed that donepezil 5 mg improves cognition slightly, although the size of the effect is unlikely to be clinically important. […] Donepezil 10 mg (MD 2.21 ADAS-Cog points, 95% CI 3.07 to 1.35; moderate-certainty evidence) and galantamine 16 to 24 mg (MD 2.01 ADAS-Cog point, 95%CI 3.18 to 0.85; moderate-certainty evidence) probably also improve cognition, although the larger effect estimates still may not be clinically important.

• #26 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Donepezil had a beneficial effect on cognitive function, global assessment, and activities of daily living. […] Rivastigmine’s efficacy in vascular dementia has been studied insufficiently to draw any meaningful conclusions. […] Hydergine had statistically significant benefits on global measures in an apparent dose-dependent manner. […] Nicergoline may have a beneficial effect in vascular dementia but further studies with patients diagnosed using modern day diagnostic criteria are needed to confirm these findings. […] Nimodipine studies suggest that voltage-dependent Ca2+ channels play a limited, if any, role in pathogenesis of vascular dementia related symptoms and voltage-dependent Ca2+ channel antagonists such as nimodipine are not likely to be useful in their treatment. […] CDP-choline results in a modest but statistically significant improvement in memory, behavior and global function.

• #27 Pharmacological Treatment of Vascular Dementia | SpringerLink

  https://link.springer.com/chapter/10.1385/1-59259-824-2:297

  Long-term safety and cognitive effects of galantamine in the treatment of probable vascular dementia or Alzheimers disease with cerebrovascular disease. […] Rivastigmine in subcortical vascular dementia: a comparison trial on efficacy and tolerability for 12 months follow-up. […] An efficacy and safety analysis of Exelon in Alzheimers disease with concurrent vascular risk factors. […] Rivastigmine in patients with Alzheimers disease and concurrent hypertension.

• #28 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Vascular dementia is a common condition for which there are no effective approved pharmacological treatments available. […] Despite all of the recent investment in experimental and clinical neuroscience, there are no effective pharmacological compounds approved for treatment of vascular dementia in any jurisdiction worldwide. […] Treatment of vascular dementia has also received extensive coverage. […] The prevailing conclusion of these reports is that most vascular dementia trials have produced disappointing results. It is important to note that so far no drug has been approved by regulatory agencies to treat vascular dementia. […] Memantine, an NMDA receptor antagonist, has a positive effect on cognition in patients with vascular dementia. […] Galantamine seems to improve working memory in vascular dementia patients, but it does not have a clearly documented clinical benefit in vascular dementia.

• #29 Clinical Trials of New Drugs for Vascular Cognitive Impairment and Vascular Dementia

  https://www.mdpi.com/1422-0067/23/19/11067

  A Cochrane Library review of two studies of approximately 750 participants concluded that memantine confers small clinical benefits for cognitive function with low-to-moderate certainty. […] The primary end points of several trials were scores on the EuroQol-5 dimension (EQ-5D), Montreal cognitive assessment (NCT03759938 and NCT05046106), and verbal learning test (NCT04854811). […] In short, the trend of drug development in VCI and VaD treatment has changed over time based on a growing understanding of the disease’s pathophysiology and the advances in diagnosis and measurement. However, international pharmaceutical companies’ investment in new drugs targeting VCI is insufficient.

• #30 What are the treatments for dementia? – NHS

  https://www.nhs.uk/conditions/dementia/about-dementia/treatment/

  There is currently no cure for dementia. But there are medicines and other treatments that can help with dementia symptoms. […] The main medicines are: […] There’s evidence that these medicines can also help treat dementia with Lewy bodies and Parkinson’s disease dementia, as well as people who have a mixed dementia diagnosis of Alzheimer’s disease with vascular dementia. […] This medicine (also known as Ebixa, Marixino or Valios) is given to people with moderate or severe Alzheimer’s disease, dementia with Lewy bodies and those with a combination of Alzheimer’s disease and vascular dementia. […] There are some conditions, such as heart problems, that can affect symptoms of dementia, particularly vascular dementia. It’s important that these are diagnosed and treated. […] These are the only medicines licensed for people with moderate to severe Alzheimer’s disease (risperidone and haloperidol) and vascular dementia (just haloperidol) where there’s a risk of harm to themselves or others.

• #31 Treatment and support for vascular dementia | Alzheimer’s Society

  https://www.alzheimers.org.uk/about-dementia/types-dementia/treatment-and-support-vascular-dementia

  There is currently no cure for vascular dementia. However, a range of treatments and support are available to help someone with a diagnosis to live well with the condition. […] The drugs that are prescribed for Alzheimers disease and dementia with Lewy bodies do not have benefits for vascular dementia, and so are not recommended for it. However, these drugs may be prescribed to treat these types if they are present in mixed dementia along with vascular dementia. […] There are a variety of activities and therapies that can help a person with dementia to maintain their abilities for as long as possible and to look after their physical and emotional wellbeing. […] Cognitive stimulation therapy (CST) this is a popular way to help keep someones mind active. It involves doing themed activity sessions over several weeks.

• #32 Vascular Dementia Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/292105-treatment

  Regular follow-up every 46 months is recommended to assess the patient’s general condition and cognitive and noncognitive symptoms. […] Treatment of risk factors such as hypertension, hypercholesterolemia, and diabetes mellitus require special attention. […] The mainstay of management of vascular dementia is the prevention of new strokes. This includes administering antiplatelet drugs and controlling major vascular risk factors. Aspirin has also been found to slow the progression of vascular dementia. […] Drug treatment is primarily used to prevent further worsening of vascular dementia by treating the underlying disease such as hypertension, hyperlipidemia, and diabetes mellitus. Antiplatelet agents are indicated. […] Pentoxifylline and, to a more limited extent, ergoloid mesylates (Hydergine), may be useful for increasing cerebral blood flow.

• #33 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Donepezil had a beneficial effect on cognitive function, global assessment, and activities of daily living. […] Rivastigmine’s efficacy in vascular dementia has been studied insufficiently to draw any meaningful conclusions. […] Hydergine had statistically significant benefits on global measures in an apparent dose-dependent manner. […] Nicergoline may have a beneficial effect in vascular dementia but further studies with patients diagnosed using modern day diagnostic criteria are needed to confirm these findings. […] Nimodipine studies suggest that voltage-dependent Ca2+ channels play a limited, if any, role in pathogenesis of vascular dementia related symptoms and voltage-dependent Ca2+ channel antagonists such as nimodipine are not likely to be useful in their treatment. […] CDP-choline results in a modest but statistically significant improvement in memory, behavior and global function.

• #34 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Donepezil had a beneficial effect on cognitive function, global assessment, and activities of daily living. […] Rivastigmine’s efficacy in vascular dementia has been studied insufficiently to draw any meaningful conclusions. […] Hydergine had statistically significant benefits on global measures in an apparent dose-dependent manner. […] Nicergoline may have a beneficial effect in vascular dementia but further studies with patients diagnosed using modern day diagnostic criteria are needed to confirm these findings. […] Nimodipine studies suggest that voltage-dependent Ca2+ channels play a limited, if any, role in pathogenesis of vascular dementia related symptoms and voltage-dependent Ca2+ channel antagonists such as nimodipine are not likely to be useful in their treatment. […] CDP-choline results in a modest but statistically significant improvement in memory, behavior and global function.

• #35 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Donepezil had a beneficial effect on cognitive function, global assessment, and activities of daily living. […] Rivastigmine’s efficacy in vascular dementia has been studied insufficiently to draw any meaningful conclusions. […] Hydergine had statistically significant benefits on global measures in an apparent dose-dependent manner. […] Nicergoline may have a beneficial effect in vascular dementia but further studies with patients diagnosed using modern day diagnostic criteria are needed to confirm these findings. […] Nimodipine studies suggest that voltage-dependent Ca2+ channels play a limited, if any, role in pathogenesis of vascular dementia related symptoms and voltage-dependent Ca2+ channel antagonists such as nimodipine are not likely to be useful in their treatment. […] CDP-choline results in a modest but statistically significant improvement in memory, behavior and global function.

• #36 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Donepezil had a beneficial effect on cognitive function, global assessment, and activities of daily living. […] Rivastigmine’s efficacy in vascular dementia has been studied insufficiently to draw any meaningful conclusions. […] Hydergine had statistically significant benefits on global measures in an apparent dose-dependent manner. […] Nicergoline may have a beneficial effect in vascular dementia but further studies with patients diagnosed using modern day diagnostic criteria are needed to confirm these findings. […] Nimodipine studies suggest that voltage-dependent Ca2+ channels play a limited, if any, role in pathogenesis of vascular dementia related symptoms and voltage-dependent Ca2+ channel antagonists such as nimodipine are not likely to be useful in their treatment. […] CDP-choline results in a modest but statistically significant improvement in memory, behavior and global function.

• #37 Vascular dementia: Pharmacological treatment approaches and perspectives

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2685259/

  Folic acid showed no benefit for improving cognition. […] Validation therapy was examined for this review because of the recent attention paid to its legitimacy and efficacy. […] From the studies reviewed here, one may draw several conclusions. First, there are relatively few studies on vascular dementia treatment and no compound has been approved by any regulatory body for treatment of vascular dementia.

• #38 Potential new drug for incurable vascular dementia

  https://www.manchester.ac.uk/about/news/potential-new-drug-for-incurable-vascular-dementia/

  A drug already used to treat high blood pressure could be re-purposed as the first treatment to tackle a type of vascular dementia caused by damaged and leaky small blood vessels in the brain, according to research part-funded by the British Heart Foundation and published today in the Journal of Clinical Investigation. […] Now, researchers at the University of Manchester working with colleagues in the USA have discovered that the blood pressure drug amlodipine could help treat vascular dementia or stop it in the early stages. […] The team now hope to trial amlodipine as an effective treatment for vascular dementia in humans. If successful, it would be the first clinically proven treatment for vascular dementia as a result of small vessel disease and could be used in those with early signs of the condition to prevent further progression.

• #39 £2.25 Million Trial for Vascular Dementia Treatment | Technology Networks

  https://www.technologynetworks.com/tn/news/225-million-trial-for-vascular-dementia-treatment-184447

  The trial, which is funded jointly by the Alzheimers Society and the British Heart Foundation, is the first ever large clinical trial for patients with subcortical vascular dementia. […] There are currently no available treatments for vascular dementia. […] Researchers from the School of Medicine, Dentistry and Biomedical Sciences at Queens will recruit nearly 600 people with vascular dementia for the trial. […] This will be the largest study to specifically test the drugs in people with vascular dementia, the most common type of dementia after Alzheimers disease. […] Amlodipine is used to treat high blood pressure, a major risk factor for vascular dementia. […] Professor Peter Passmore from the School of Medicine, Dentistry and Biomedical Sciences, and lead investigator, said: Vascular dementia is a very common disease and to date no major trial has been successful in developing an effective treatment for this disease.

• #40 Vascular dementia treatments | Stroke Association

  https://www.stroke.org.uk/stroke/effects/vascular-dementia/treatments

  At the moment there are no treatments that cure vascular dementia, but there are treatments to help with many of the symptoms. […] Although there is no proven treatment for vascular dementia, it may be possible to prevent mild problems developing into dementia. Vascular dementia can cause problems like depression, anxiety and falls. The stroke or dementia team can work with you to find ways around many of these problems. You might have medication for anxiety, or therapy such occupational therapy, speech and language therapy and psychological therapies to help you live with dementia. […] Sometimes medication may be used to improve your mood if you are feeling very down or depressed. Medication can also help with some of the problems seen in advanced vascular dementia. […] Memory and stroke services often have a team of experts that can help with various dementia problems.

• #41 Vascular Dementia Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/292105-treatment

  Neuroprotective drugs such as nimodipine, propentofylline, and posatirelin are currently under study and may be useful for vascular dementia. […] Increasing evidence supports the involvement of the cholinergic system in vascular dementia, similar to that seen in Alzheimer dementia. […] The general management of dementia includes appropriate referral to community services, judgment and decision-making regarding legal and ethical issues (eg, driving, competency, advance directives), and consideration of caregiver stress. […] Agitation and psychosis are common in older adults with dementia and are challenging to manage. Relatively few studies have examined the use of antidepressants for the treatment of agitation and psychosis in dementia; however, the selective serotonin reuptake inhibitors (SSRIs) sertraline and citalopram appear to be associated with a reduction in symptoms of agitation when compared with placebo.

• #42 Treatment of Vascular Dementia

  https://www.brightfocus.org/resource/treatment-of-vascular-dementia/

  Learn about the treatment options for vascular cognitive impairment (VCI) a term that includes the spectrum from mild cognitive changes to severe dementia. […] What can Mrs. Wilson do? So far, no medication has been approved for the treatment of VCI but the medicines used for AD are often used off-label in patients with VCI. […] Unfortunately, the effects of cholinesterase inhibitors, (such as Aricept or Exelon), and Namenda on VCI symptoms has been very limited in the small number of studies that explore this question. […] Some experimental medications are being studied for treatment of VCI. […] So far, though, the most promising evidence supports prevention. […] We treated her depression with sertraline. We encouraged her to lose weight, increase her physical exercise, eat a Mediterranean-type diet, and keep active mentally and socially. […] As we await the availability of a VCI-reducing medication, these preventive lifestyle changes are our best tools for improving Mrs. Wilsons current quality of life and delaying or preventing progression to dementia.

• #43

  https://www.nhs.uk/conditions/vascular-dementia/treatment/

  Treatment can help prevent further damage to the brain in people with vascular dementia and may slow down its progression. […] But there’s currently no cure for the condition or a way to reverse the damage that’s already happened. […] The main aim of treatment for vascular dementia is to treat the underlying cause to help stop the condition getting worse. […] Medicines may also be offered to treat the underlying cause of vascular dementia and help stop it getting worse. […] An antipsychotic medicine, such as haloperidol or risperidone, may sometimes be given to people showing persistent aggression or extreme distress where there’s a risk of harm to themselves or others. […] Alzheimer’s disease medicines, such as donepezil (Aricept), galantamine (Reminyl), rivastigmine (Exelon) or memantine are not used to treat vascular dementia, but may be used in people who have a combination of vascular dementia and Alzheimer’s disease. […] There are also several therapies and practical measures that can help make everyday living easier for someone with dementia. […] It can also be helpful to get in touch with a support group, such as the Alzheimer’s Society or Dementia UK.

• #44 Vascular Dementia: Causes and Treatment | Doctor

  https://patient.info/doctor/vascular-dementia

  NICE does not recommend the use of antipsychotics for mild-to-moderate non-cognitive symptoms in dementia with VaD or mixed dementia because of the increased risk of cerebrovascular adverse events and death. […] VaD is modifiable and preventable. Modifying vascular risk factors in mid-life may help to prevent stroke and VaD. The single most important modifiable risk factor in mid-life is hypertension, but the value of treating this is more debatable as age increases.

• #45 Vascular dementia treatments – Alzheimer’s Research UK

  https://www.alzheimersresearchuk.org/dementia-information/types-of-dementia/vascular-dementia/treatments/

  There may also be other therapies offered in your local area that could help; these might include exercise or group activities such as music therapy. […] You may be offered an antidepressant drug, either as an alternative to CBT or in combination with it. There are different types, or classes, of antidepressant; some are not suitable for people with dementia. Your doctor will be able to advise you if an antidepressant could help and which type would be best. […] If someone experiences severe and distressing symptoms that can’t be controlled without medication, then antipsychotic drugs may be considered. These drugs help correct the imbalance of chemicals in the brain that cause symptoms like aggression. However, there are severe side effects, and they are not suitable for everyone. Anyone taking antipsychotics should be carefully and regularly monitored by the doctor.

• #46 Vascular Dementia: Causes and Treatment | Doctor

  https://patient.info/doctor/vascular-dementia

  NICE does not recommend the use of antipsychotics for mild-to-moderate non-cognitive symptoms in dementia with VaD or mixed dementia because of the increased risk of cerebrovascular adverse events and death. […] VaD is modifiable and preventable. Modifying vascular risk factors in mid-life may help to prevent stroke and VaD. The single most important modifiable risk factor in mid-life is hypertension, but the value of treating this is more debatable as age increases.

• #47 Treatment and support for vascular dementia | Alzheimer’s Society

  https://www.alzheimers.org.uk/about-dementia/types-dementia/treatment-and-support-vascular-dementia

  There is currently no cure for vascular dementia. However, a range of treatments and support are available to help someone with a diagnosis to live well with the condition. […] The drugs that are prescribed for Alzheimers disease and dementia with Lewy bodies do not have benefits for vascular dementia, and so are not recommended for it. However, these drugs may be prescribed to treat these types if they are present in mixed dementia along with vascular dementia. […] There are a variety of activities and therapies that can help a person with dementia to maintain their abilities for as long as possible and to look after their physical and emotional wellbeing. […] Cognitive stimulation therapy (CST) this is a popular way to help keep someones mind active. It involves doing themed activity sessions over several weeks.

• #48 Treatment and support for vascular dementia | Alzheimer’s Society

  https://www.alzheimers.org.uk/about-dementia/types-dementia/treatment-and-support-vascular-dementia

  There is currently no cure for vascular dementia. However, a range of treatments and support are available to help someone with a diagnosis to live well with the condition. […] The drugs that are prescribed for Alzheimers disease and dementia with Lewy bodies do not have benefits for vascular dementia, and so are not recommended for it. However, these drugs may be prescribed to treat these types if they are present in mixed dementia along with vascular dementia. […] There are a variety of activities and therapies that can help a person with dementia to maintain their abilities for as long as possible and to look after their physical and emotional wellbeing. […] Cognitive stimulation therapy (CST) this is a popular way to help keep someones mind active. It involves doing themed activity sessions over several weeks.

• #49 Open Access Macedonian Journal of Medical Sciences (OAMJMS).

  https://oamjms.eu/index.php/mjms/article/view/5585

  Cognitive stimulation therapy (CST) is a restoration therapy based on cognitive improvement of patients, by giving patients a variety of stimulation. This therapy is highly recommended for people with mild dementia from mild to moderate in either Alzheimer dementia or vascular dementia. […] Cognitive stimulation is the best intervention option in the treatment of mild to moderate vascular dementia. This case is one good example that shows the success of CST that has been observed for 9 months, not only on the cognitive component but also in terms of the ability to perform daily activities.

• #50 Treating vascular dementia | informedhealth.org

  https://www.informedhealth.org/treating-vascular-dementia.html

  Cognitive stimulation therapy involves various mental exercises for people with mild to moderate dementia. They include things like mental arithmetic, orientation exercises, conversation, and creative work such as painting, handicrafts, and pottery. […] Reminiscence therapy can lift peoples mood and slightly improve their mental ability. It is recommended for all stages of the disease. […] Occupational therapy is an effective way to practice the skills a person needs in day-to-day life, like getting dressed and doing housework. […] Physical activity provides a range of health benefits for people with vascular dementia. […] Music therapy helps to lift peoples mood and make them feel calmer. […] Medication can help prevent further strokes and additional brain damage. […] Statins are drugs that can prevent strokes and heart attacks.

• #51 Treatment and support for vascular dementia | Alzheimer’s Society

  https://www.alzheimers.org.uk/about-dementia/types-dementia/treatment-and-support-vascular-dementia

  Cognitive rehabilitation this is skills training that is tailored to a persons needs and abilities. It can enable the person to keep their thinking skills, meet their goals and cope better with the symptoms of dementia. […] Talking therapies, such as counselling these can help someone come to terms with their diagnosis or discuss their feelings. […] Cognitive behavioural therapy (CBT) this may be offered if the person develops depression or anxiety. It is most useful in the early stages of dementia. […] Occupational therapy (OT) an occupational therapist will provide advice and support on ways to help someone with dementia stay independent and live well with vascular dementia at home. […] Music and creative arts therapies these are therapeutic sessions where the person can be creative, such as making music, playing an instrument, and painting.

• #52 What are the treatments for dementia? – NHS

  https://www.nhs.uk/conditions/dementia/about-dementia/treatment/

  Haloperidol can be used only if other treatments have not helped. […] Medicines for dementia symptoms are important, but are only one part of the care for a person with dementia. Other treatments, activities and support for the carer, too are just as important in helping people to live well with dementia. […] Evidence suggests that CST benefits people with mild to moderate dementia. […] Cognitive rehabilitation works by getting you to use the parts of your brain that are working to help the parts that are not. In the early stages of dementia, it can help you cope better with the condition. […] Evidence shows that they can improve mood and wellbeing. They also help you and those around you to focus on your skills and achievements rather than on your dementia.

• #53 Treatment and support for vascular dementia | Alzheimer’s Society

  https://www.alzheimers.org.uk/about-dementia/types-dementia/treatment-and-support-vascular-dementia

  Cognitive rehabilitation this is skills training that is tailored to a persons needs and abilities. It can enable the person to keep their thinking skills, meet their goals and cope better with the symptoms of dementia. […] Talking therapies, such as counselling these can help someone come to terms with their diagnosis or discuss their feelings. […] Cognitive behavioural therapy (CBT) this may be offered if the person develops depression or anxiety. It is most useful in the early stages of dementia. […] Occupational therapy (OT) an occupational therapist will provide advice and support on ways to help someone with dementia stay independent and live well with vascular dementia at home. […] Music and creative arts therapies these are therapeutic sessions where the person can be creative, such as making music, playing an instrument, and painting.

• #54 Treating vascular dementia | informedhealth.org

  https://www.informedhealth.org/treating-vascular-dementia.html

  Cognitive stimulation therapy involves various mental exercises for people with mild to moderate dementia. They include things like mental arithmetic, orientation exercises, conversation, and creative work such as painting, handicrafts, and pottery. […] Reminiscence therapy can lift peoples mood and slightly improve their mental ability. It is recommended for all stages of the disease. […] Occupational therapy is an effective way to practice the skills a person needs in day-to-day life, like getting dressed and doing housework. […] Physical activity provides a range of health benefits for people with vascular dementia. […] Music therapy helps to lift peoples mood and make them feel calmer. […] Medication can help prevent further strokes and additional brain damage. […] Statins are drugs that can prevent strokes and heart attacks.

• #55 Treatment and support for vascular dementia | Alzheimer’s Society

  https://www.alzheimers.org.uk/about-dementia/types-dementia/treatment-and-support-vascular-dementia

  Cognitive rehabilitation this is skills training that is tailored to a persons needs and abilities. It can enable the person to keep their thinking skills, meet their goals and cope better with the symptoms of dementia. […] Talking therapies, such as counselling these can help someone come to terms with their diagnosis or discuss their feelings. […] Cognitive behavioural therapy (CBT) this may be offered if the person develops depression or anxiety. It is most useful in the early stages of dementia. […] Occupational therapy (OT) an occupational therapist will provide advice and support on ways to help someone with dementia stay independent and live well with vascular dementia at home. […] Music and creative arts therapies these are therapeutic sessions where the person can be creative, such as making music, playing an instrument, and painting.

• #56 Treating vascular dementia | informedhealth.org

  https://www.informedhealth.org/treating-vascular-dementia.html

  Cognitive stimulation therapy involves various mental exercises for people with mild to moderate dementia. They include things like mental arithmetic, orientation exercises, conversation, and creative work such as painting, handicrafts, and pottery. […] Reminiscence therapy can lift peoples mood and slightly improve their mental ability. It is recommended for all stages of the disease. […] Occupational therapy is an effective way to practice the skills a person needs in day-to-day life, like getting dressed and doing housework. […] Physical activity provides a range of health benefits for people with vascular dementia. […] Music therapy helps to lift peoples mood and make them feel calmer. […] Medication can help prevent further strokes and additional brain damage. […] Statins are drugs that can prevent strokes and heart attacks.

• #57 Treating vascular dementia | informedhealth.org

  https://www.informedhealth.org/treating-vascular-dementia.html

  Cognitive stimulation therapy involves various mental exercises for people with mild to moderate dementia. They include things like mental arithmetic, orientation exercises, conversation, and creative work such as painting, handicrafts, and pottery. […] Reminiscence therapy can lift peoples mood and slightly improve their mental ability. It is recommended for all stages of the disease. […] Occupational therapy is an effective way to practice the skills a person needs in day-to-day life, like getting dressed and doing housework. […] Physical activity provides a range of health benefits for people with vascular dementia. […] Music therapy helps to lift peoples mood and make them feel calmer. […] Medication can help prevent further strokes and additional brain damage. […] Statins are drugs that can prevent strokes and heart attacks.

• #58 Dementia Treatments: Medication, Therapy, Diet, and Exercise

  https://www.webmd.com/alzheimers/dementia-treatments-overview

  No medication can cure dementia. But some may help with some of the symptoms for a time. And doctors may prescribe other meds to treat problems brought on by dementia, such as depression, trouble sleeping, or crankiness. […] These approaches might help jog your loved ones memory and thinking skills or at least give them pleasure and brighten their day. Make sure anything they try helps their quality of life and doesnt make them feel frustrated or overwhelmed. […] Reminiscence therapy might include things like talking with your loved one about their hometown, school days, work life, or favorite hobbies. It can be done one-on-one or in groups as part of an organized therapy. […] Cognitive stimulation therapy (CST) is a structured program for groups of people with mild to moderate dementia.

• #59 Treatment and support for vascular dementia | Alzheimer’s Society

  https://www.alzheimers.org.uk/about-dementia/types-dementia/treatment-and-support-vascular-dementia

  Cognitive rehabilitation this is skills training that is tailored to a persons needs and abilities. It can enable the person to keep their thinking skills, meet their goals and cope better with the symptoms of dementia. […] Talking therapies, such as counselling these can help someone come to terms with their diagnosis or discuss their feelings. […] Cognitive behavioural therapy (CBT) this may be offered if the person develops depression or anxiety. It is most useful in the early stages of dementia. […] Occupational therapy (OT) an occupational therapist will provide advice and support on ways to help someone with dementia stay independent and live well with vascular dementia at home. […] Music and creative arts therapies these are therapeutic sessions where the person can be creative, such as making music, playing an instrument, and painting.

• #60 Vascular dementia treatments – Alzheimer’s Research UK

  https://www.alzheimersresearchuk.org/dementia-information/types-of-dementia/vascular-dementia/treatments/

  People diagnosed with vascular dementia may benefit from cognitive therapy. These activities are designed to stimulate thinking skills and engage people. They are often group-based and include games and discussions to encourage socialising. Speech therapy may also help to improve communication problems. […] For people with both vascular dementia and Alzheimer’s (mixed dementia), there are some drugs used to treat Alzheimer’s disease that may help with the symptoms of mixed dementia. If you’ve been diagnosed with mixed dementia you can discuss these treatment options with your doctor. […] Your doctor may consider recommending cognitive behavioural therapy (CBT). CBT provides an opportunity for people to talk about their worries and concerns with a specialist practitioner. It aims to help people develop different ways of thinking and behaving.

• #61 Treatment and support for vascular dementia | Alzheimer’s Society

  https://www.alzheimers.org.uk/about-dementia/types-dementia/treatment-and-support-vascular-dementia

  There is also a range of support services that can help a person live well with dementia. These include local dementia advisers and dementia support workers who can offer support, practical advice and information over the phone, face to face or online. […] Support from a speech and language therapist (SLT) is often helpful if the person develops problems with swallowing or speaking, which are particularly common after having a stroke. […] Planning for end of life is important for anyone who has a life-limiting condition, such as vascular dementia.

• #62 Vascular Dementia: What It Is, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/22216-vascular-dementia

  You may work with specialists to help manage symptoms of vascular dementia. For example, physical and occupational therapists can help you improve your physical abilities and find new ways of doing everyday tasks. A speech-language pathologist can help with speaking, swallowing and learning other ways to communicate. […] These specialists will work with you and your loved ones to make sure you have ongoing care that matches your needs and goals. They’ll advise you and your loved ones on advance care planning for financial and healthcare decisions. They’ll also make referrals for palliative care or hospice when vascular dementia has progressed to its later or end stages.

• #63 Vascular Dementia: Signs, Symptoms, and Treatment

  https://www.helpguide.org/aging/dementia/vascular-dementia

  Vascular dementia treatment is focused on managing symptoms and preventing further strokes. […] While there is currently no cure for vascular dementia, the earlier any brain damage is caught, the better your chance of preventing dementia, or at least slowing down the progression of the disease. […] By treating the risk factors that led to vascular dementia, such as high blood pressure or diabetes, you may even be able to reverse some of the symptoms. […] Physiotherapy, occupational therapy, and speech therapy can help you to regain some or all of any lost functions following a stroke. […] A number of medications used to treat the cognitive symptoms of Alzheimer’s disease appear to work for vascular dementia, too. […] Lowering your risk for stroke can reduce your risk for developing vascular dementia or, if you’ve already been diagnosed, it can help you slow the progression of symptoms. […] In addition to medication, adopting healthier lifestyle changes is also a vital part of vascular dementia treatment.

• #64 Dementia Treatment: Medication, Therapeutic, and More

  https://www.healthline.com/health/dementia/dementia-treatment

  Dementia treatment is more than just medication. It can include lifestyle changes, multimodal therapy, and environmental management, as well. […] As dementia progresses and more personal care assistance is needed, treatments focus on improving quality of life, reducing symptom severity, and slowing disease progression, if possible. […] Theres currently no cure for dementia, but treatment can help ease symptoms and improve overall quality of life. In some cases, it can also slow the diseases progression. […] Certain forms of dementia, such as vascular dementia, may be a part of the progression of health conditions like diabetes or heart disease. […] Lifestyle changes can be a big part of nonmedication dementia treatment. […] Therapy can also help you develop useful skills for daily task management as your functionality changes.

• #65 Vascular dementia treatments – Alzheimer’s Research UK

  https://www.alzheimersresearchuk.org/dementia-information/types-of-dementia/vascular-dementia/treatments/

  While there are currently no specific treatments for vascular dementia, a doctor may prescribe medication to treat the risk factors like high blood pressure or diabetes which can cause damage to blood vessels in our brains. […] There are currently no treatments that can reverse the brain cell damage that causes vascular dementia. However, a doctor may prescribe or monitor medicines used to treat underlying conditions that can lead to vascular dementia. […] When someone is diagnosed with vascular dementia, their doctor will test for underlying causes that can affect brain health and prescribe medications. These include: diabetes, stroke, high blood pressure, high cholesterol, heart problems. […] A doctor will also advise making healthy lifestyle changes to help limit the damage caused by these underlying conditions. This could include stopping smoking, doing more exercise, maintaining a healthy weight and eating a balanced diet.

• #66 Treating vascular dementia | informedhealth.org

  https://www.informedhealth.org/treating-vascular-dementia.html

  Cognitive stimulation therapy involves various mental exercises for people with mild to moderate dementia. They include things like mental arithmetic, orientation exercises, conversation, and creative work such as painting, handicrafts, and pottery. […] Reminiscence therapy can lift peoples mood and slightly improve their mental ability. It is recommended for all stages of the disease. […] Occupational therapy is an effective way to practice the skills a person needs in day-to-day life, like getting dressed and doing housework. […] Physical activity provides a range of health benefits for people with vascular dementia. […] Music therapy helps to lift peoples mood and make them feel calmer. […] Medication can help prevent further strokes and additional brain damage. […] Statins are drugs that can prevent strokes and heart attacks.

• #67 Dementia Treatments: Medication, Therapy, Diet, and Exercise

  https://www.webmd.com/alzheimers/dementia-treatments-overview

  Reality orientation training goes over basic things like the persons name and the date and time. […] Research shows that exercise may slow down dementia symptoms, such as thinking problems, and ease anxiety or depression. […] The MIND diet includes: Vegetables, especially leafy greens (think of spinach, kale, and other greens), Nuts, Berries, Beans, Whole grains, Fish, Poultry, Olive oil, Wine. […] Keep in mind that eating isnt just about nutrients and calories. Its also social and personal, and a source of enjoyment. […] Stay organized. Keep a calendar and other easy-to-see reminders around their home to help them remember upcoming events and plans. […] Schedule a vision checkup with your loved ones eye doctor to see if they need a new eyeglass prescription. Also, ask their primary doctor to refer you to a doctor who can do a hearing test to give them a new hearing aid, if needed. […] If your loved one needs help coming to terms with it, ask the doctor treating their dementia to refer you to a trained mental health professional.

• #68 Your Guide to Vascular Dementia Self-Care Strategies

  https://www.healthline.com/health/dementia/vascular-dementia-self-care

  Vascular dementia is caused by stroke damage in the brain. […] Theres currently no cure for vascular dementia, but self-care is an important part of treatment that may slow or help prevent further damage to your brain. […] Most of the self-care strategies for vascular dementia are the same as those for other types of dementia. […] Physical self-care for vascular dementia varies based on the underlying cause, but certain lifestyle modifications are universally beneficial. […] Regular exercise can help manage factors like body weight that contribute to vascular diseases, but it also directly promotes blood vessel health. […] A balanced diet can help improve underlying conditions like hypertension, diabetes, or heart disease that can cause vascular dementia. […] Stopping smoking has immediate benefits, and within 1 year of quitting, your risk for cardiovascular diseases drops dramatically.

• #69 Dementia Treatments: Medication, Therapy, Diet, and Exercise

  https://www.webmd.com/alzheimers/dementia-treatments-overview

  Reality orientation training goes over basic things like the persons name and the date and time. […] Research shows that exercise may slow down dementia symptoms, such as thinking problems, and ease anxiety or depression. […] The MIND diet includes: Vegetables, especially leafy greens (think of spinach, kale, and other greens), Nuts, Berries, Beans, Whole grains, Fish, Poultry, Olive oil, Wine. […] Keep in mind that eating isnt just about nutrients and calories. Its also social and personal, and a source of enjoyment. […] Stay organized. Keep a calendar and other easy-to-see reminders around their home to help them remember upcoming events and plans. […] Schedule a vision checkup with your loved ones eye doctor to see if they need a new eyeglass prescription. Also, ask their primary doctor to refer you to a doctor who can do a hearing test to give them a new hearing aid, if needed. […] If your loved one needs help coming to terms with it, ask the doctor treating their dementia to refer you to a trained mental health professional.

• #70 Treatment of Vascular Dementia

  https://www.brightfocus.org/resource/treatment-of-vascular-dementia/

  Learn about the treatment options for vascular cognitive impairment (VCI) a term that includes the spectrum from mild cognitive changes to severe dementia. […] What can Mrs. Wilson do? So far, no medication has been approved for the treatment of VCI but the medicines used for AD are often used off-label in patients with VCI. […] Unfortunately, the effects of cholinesterase inhibitors, (such as Aricept or Exelon), and Namenda on VCI symptoms has been very limited in the small number of studies that explore this question. […] Some experimental medications are being studied for treatment of VCI. […] So far, though, the most promising evidence supports prevention. […] We treated her depression with sertraline. We encouraged her to lose weight, increase her physical exercise, eat a Mediterranean-type diet, and keep active mentally and socially. […] As we await the availability of a VCI-reducing medication, these preventive lifestyle changes are our best tools for improving Mrs. Wilsons current quality of life and delaying or preventing progression to dementia.

• #71 Your Guide to Vascular Dementia Self-Care Strategies

  https://www.healthline.com/health/dementia/vascular-dementia-self-care

  Vascular dementia is caused by stroke damage in the brain. […] Theres currently no cure for vascular dementia, but self-care is an important part of treatment that may slow or help prevent further damage to your brain. […] Most of the self-care strategies for vascular dementia are the same as those for other types of dementia. […] Physical self-care for vascular dementia varies based on the underlying cause, but certain lifestyle modifications are universally beneficial. […] Regular exercise can help manage factors like body weight that contribute to vascular diseases, but it also directly promotes blood vessel health. […] A balanced diet can help improve underlying conditions like hypertension, diabetes, or heart disease that can cause vascular dementia. […] Stopping smoking has immediate benefits, and within 1 year of quitting, your risk for cardiovascular diseases drops dramatically.

• #72 Your Guide to Vascular Dementia Self-Care Strategies

  https://www.healthline.com/health/dementia/vascular-dementia-self-care

  By lowering your alcohol consumption, you may reduce the damage these conditions cause to your vascular system. […] Stress relief as vascular dementia self-care can include practices like meditation or deep breathing exercises, journaling or art therapy, spending time in nature, and talking with a therapist. […] Your mental health when living with vascular dementia is just as important as your physical health. […] Brain exercises have been shown to improve cognitive function among adults with normal cognition, but theres currently insufficient evidence to prove they can slow or stop dementia-related cognitive decline. […] Quality of life strategies to lessen dementias toll on your day include creating a written daily plan of chores, meals, recreation, and responsibilities. […] Its never too early to speak to a mental health professional. […] If youve been diagnosed with vascular dementia, your doctor will recommend targeted self-care approaches based on your underlying conditions and severity of symptoms.

• #73 Your Guide to Vascular Dementia Self-Care Strategies

  https://www.healthline.com/health/dementia/vascular-dementia-self-care

  By lowering your alcohol consumption, you may reduce the damage these conditions cause to your vascular system. […] Stress relief as vascular dementia self-care can include practices like meditation or deep breathing exercises, journaling or art therapy, spending time in nature, and talking with a therapist. […] Your mental health when living with vascular dementia is just as important as your physical health. […] Brain exercises have been shown to improve cognitive function among adults with normal cognition, but theres currently insufficient evidence to prove they can slow or stop dementia-related cognitive decline. […] Quality of life strategies to lessen dementias toll on your day include creating a written daily plan of chores, meals, recreation, and responsibilities. […] Its never too early to speak to a mental health professional. […] If youve been diagnosed with vascular dementia, your doctor will recommend targeted self-care approaches based on your underlying conditions and severity of symptoms.

• #74 Vascular Dementia: What It Is, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/22216-vascular-dementia

  You may work with specialists to help manage symptoms of vascular dementia. For example, physical and occupational therapists can help you improve your physical abilities and find new ways of doing everyday tasks. A speech-language pathologist can help with speaking, swallowing and learning other ways to communicate. […] These specialists will work with you and your loved ones to make sure you have ongoing care that matches your needs and goals. They’ll advise you and your loved ones on advance care planning for financial and healthcare decisions. They’ll also make referrals for palliative care or hospice when vascular dementia has progressed to its later or end stages.

• #75

  https://www.nhs.uk/conditions/vascular-dementia/treatment/

  Treatment can help prevent further damage to the brain in people with vascular dementia and may slow down its progression. […] But there’s currently no cure for the condition or a way to reverse the damage that’s already happened. […] The main aim of treatment for vascular dementia is to treat the underlying cause to help stop the condition getting worse. […] Medicines may also be offered to treat the underlying cause of vascular dementia and help stop it getting worse. […] An antipsychotic medicine, such as haloperidol or risperidone, may sometimes be given to people showing persistent aggression or extreme distress where there’s a risk of harm to themselves or others. […] Alzheimer’s disease medicines, such as donepezil (Aricept), galantamine (Reminyl), rivastigmine (Exelon) or memantine are not used to treat vascular dementia, but may be used in people who have a combination of vascular dementia and Alzheimer’s disease. […] There are also several therapies and practical measures that can help make everyday living easier for someone with dementia. […] It can also be helpful to get in touch with a support group, such as the Alzheimer’s Society or Dementia UK.

• #76 Treatment and support for vascular dementia | Alzheimer’s Society

  https://www.alzheimers.org.uk/about-dementia/types-dementia/treatment-and-support-vascular-dementia

  There is also a range of support services that can help a person live well with dementia. These include local dementia advisers and dementia support workers who can offer support, practical advice and information over the phone, face to face or online. […] Support from a speech and language therapist (SLT) is often helpful if the person develops problems with swallowing or speaking, which are particularly common after having a stroke. […] Planning for end of life is important for anyone who has a life-limiting condition, such as vascular dementia.

• #77 Vascular Dementia: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1135408-treatment

  The mainstay of management of vascular dementia is the prevention of new strokes. This includes administering antiplatelet drugs and controlling major vascular risk factors. Aspirin has also been found to slow the progression of vascular dementia. […] In addition to patient education, caregiver education is important to dementia management. […] Structured, respectful, and friendly caregiving is best, and it forms the most important aspect of behavioral care for patients with vascular dementia. Educating the caregiver on how to take care of these patients, how to react to certain behaviors and agitation, and how to reorient the patient improves the quality of care and treatment in these patients. Well-informed caregivers are best equipped to address the problems that vascular dementia presents.

• #78 Vascular Dementia: Practice Essentials, Background, Pathophysiology

  https://emedicine.medscape.com/article/1135408-treatment

  The mainstay of management of vascular dementia is the prevention of new strokes. This includes administering antiplatelet drugs and controlling major vascular risk factors. Aspirin has also been found to slow the progression of vascular dementia. […] In addition to patient education, caregiver education is important to dementia management. […] Structured, respectful, and friendly caregiving is best, and it forms the most important aspect of behavioral care for patients with vascular dementia. Educating the caregiver on how to take care of these patients, how to react to certain behaviors and agitation, and how to reorient the patient improves the quality of care and treatment in these patients. Well-informed caregivers are best equipped to address the problems that vascular dementia presents.

• #79 Vascular Dementia: What It Is, Symptoms & Treatment

  https://my.clevelandclinic.org/health/diseases/22216-vascular-dementia

  You may work with specialists to help manage symptoms of vascular dementia. For example, physical and occupational therapists can help you improve your physical abilities and find new ways of doing everyday tasks. A speech-language pathologist can help with speaking, swallowing and learning other ways to communicate. […] These specialists will work with you and your loved ones to make sure you have ongoing care that matches your needs and goals. They’ll advise you and your loved ones on advance care planning for financial and healthcare decisions. They’ll also make referrals for palliative care or hospice when vascular dementia has progressed to its later or end stages.

• #80 New Treatments For Vascular Dementia – Discover Right Solution

  https://www.brightpoint-md.com/life-with-dementia/exploring-new-treatment-for-vascular-dementia/

  Conventional treatments can provide some relief and assistance, but they seldom stop or decrease vascular dementia progression. Their efficacy varies greatly among individuals, underlining the need for more tailored and novel therapies. […] Vascular dementia treatment has shown signs of optimism in recent years due to growing research and novel approaches to its complexity. Innovative vascular dementia treatments have emerged from pioneering research. […] Promising therapies on the horizon often focus on enhancing cerebral blood flow, neuroprotection, and reducing the damage caused by vascular events. […] New drugs designed to target vascular dementia’s particular pathophysiology offer hope for better treatments. […] Several drugs may treat vascular dementia. These medications try to reduce symptoms and delay disease progression. Some of these drugs increase brain blood flow, while others target neuroprotection or cognitive function pathways.

• #81 Potential new drug for incurable vascular dementia

  https://www.manchester.ac.uk/about/news/potential-new-drug-for-incurable-vascular-dementia/

  A drug already used to treat high blood pressure could be re-purposed as the first treatment to tackle a type of vascular dementia caused by damaged and leaky small blood vessels in the brain, according to research part-funded by the British Heart Foundation and published today in the Journal of Clinical Investigation. […] Now, researchers at the University of Manchester working with colleagues in the USA have discovered that the blood pressure drug amlodipine could help treat vascular dementia or stop it in the early stages. […] The team now hope to trial amlodipine as an effective treatment for vascular dementia in humans. If successful, it would be the first clinically proven treatment for vascular dementia as a result of small vessel disease and could be used in those with early signs of the condition to prevent further progression.

• #82 Vascular Dementia | Alzheimer’s Drug Discovery Foundation

  https://www.alzdiscovery.org/news-room/tags/vascular+dementia/

  The ADDF and the Alzheimers Society UK have teamed up to support a trial of an erectile dysfunction drug as a possible treatment for vascular dementia. […] The ADDF and the Alzheimer’s Society UK announced new funding to explore the possibility of using tadalafil, a commonly prescribed drug which treats erectile dysfunction, as the next treatment for dementia.

• #83 A Promising Compound Herbal Treatment for Vascular Dementia | Psychology Today

  https://www.psychologytoday.com/us/blog/integrative-mental-health-care/201908/a-promising-compound-herbal-treatment-for-vascular

  The formula, called SLT, contains standardized preparations of Ginkgo biloba (ginkgo), Panax ginseng (ginseng), and Crocus sativus (saffron). […] In a small 1-week randomized placebo-controlled trial, 16 healthy adults randomized to SLT experienced improvements in working memory. […] In another small study individuals diagnosed with probable vascular dementia randomized to SLT showed significantly greater improvement in cognitive functioning, and a sub-set showed increased blood flow in brain regions associated with memory, auditory and speech processing. […] A 12-month human clinical trial on 325 individuals with probable vascular dementia found similar cognitive improvements. […] Findings of this multi-center study support that SLT significantly improves cognition and daily functioning in patients with mild to moderate symptoms of vascular dementia following 6 months of treatment. […] If findings of these studies confirm the effectiveness of SLT in vascular dementia, this Chinese herbal formula will emerge as an evidence-based herbal treatment of vascular dementia, a neurodegenerative disorder for which there is presently no effective treatment.

• #84 Clinical Trials of New Drugs for Vascular Cognitive Impairment and Vascular Dementia

  https://www.mdpi.com/1422-0067/23/19/11067

  The keyword “vascular dementia” was used to search ClinicalTrials.gov to determine agents represented in phases I, II, III, and IV. […] Of 17 randomized controlled trials (RCTs) meeting our inclusion criteria, 9 were completed in the past 10 years, whereas 8 are ongoing or in the planning stages. […] A phase III trial (NCT03804229) investigated the 52-week use of butylphthalide soft capsules (equivalent to 600 mg of NBP per day divided into three portions) on patients with VaD. […] A phase III trial involving the treatment of mild-to-moderate VaD with SLT (NCT03789760) that began in 2019 aims to validate the promising effects of SLT. […] An RCT conducted in 2020 (NCT02453932) indicated that TZ and donepezil, an anti-AD agent, exert the same therapeutic effects on cognitive function and BPSD in patients with mild-to-moderate VaD.

• #85 Clinical Trials of New Drugs for Vascular Cognitive Impairment and Vascular Dementia

  https://www.mdpi.com/1422-0067/23/19/11067

  A phase II trial (NCT 03306979) in which patients with VCI were randomly assigned to take NAC or a placebo for 24 weeks. […] A phase II RCT (registered to NCT02886494) indicated that BAC benefits cognitive function, neuropsychiatric behaviors, and ADL scores among specific dementia populations. […] Donepezil, a cholinesterase inhibitor, slightly improves cognitive function in patients with VCI. […] A Cochrane Library review concluded from the data of three trials that rivastigmine has some benefits for VCI. […] A multinational, double-blind, randomized, placebo-controlled trial reported that galantamine was effective in improving cognition in patients with VaD. […] In this review, we found a phase I, randomized, single group, open-label study (NCT00457769) which aims to determine whether donepezil improves the recollection of the steps of functional tasks.

• #86 Azthena logo with the word Azthena

  https://www.news-medical.net/news/20230807/Research-uncovers-potential-route-to-treating-vascular-dementia.aspx

  Groundbreaking new research has uncovered a potential route to developing the first ever drug treatments for vascular dementia, that directly target a cause of the condition. […] By identifying drugs that could restore this communication, the researchers hope to soon be able to improve blood supply to affected areas of the brain and slow the progression of vascular dementia. […] „By uncovering how high blood pressure causes arteries in the brain to remain constricted, our research reveals a new avenue for drug discovery that may help to find the first treatment for vascular dementia. […] Pinpointing how arteries remain permanently narrowed in vascular dementia could lead to the development of new effective treatments, raising hope that there may soon be a way to prevent this illness from destroying more lives.”

• #87 Vascular Dementia Treatment & Management: Approach Considerations, Medical Care, Diet

  https://emedicine.medscape.com/article/292105-treatment

  Regular follow-up every 46 months is recommended to assess the patient’s general condition and cognitive and noncognitive symptoms. […] Treatment of risk factors such as hypertension, hypercholesterolemia, and diabetes mellitus require special attention. […] The mainstay of management of vascular dementia is the prevention of new strokes. This includes administering antiplatelet drugs and controlling major vascular risk factors. Aspirin has also been found to slow the progression of vascular dementia. […] Drug treatment is primarily used to prevent further worsening of vascular dementia by treating the underlying disease such as hypertension, hyperlipidemia, and diabetes mellitus. Antiplatelet agents are indicated. […] Pentoxifylline and, to a more limited extent, ergoloid mesylates (Hydergine), may be useful for increasing cerebral blood flow.

• #88 Vascular dementia treatment and stages, life expectancy. – AgingCare.com

  https://www.agingcare.com/questions/vascular-dementia-treatment-and-stages-life-expectancy-490222.htm

  With Vascular Dementia the declines can be very rapid. […] Vascular dementia is managed by managing the underlying health conditions, the damage is not reversible although some people can reach a plateau and remain stable for long periods of time. […] How long do you live with vascular dementia? Vascular dementia around five years. This is lower than the average for Alzheimer’s mostly because someone with vascular dementia is more likely to die from a stroke or heart attack than from the dementia itself.

• #89

  https://www2.hse.ie/conditions/vascular-dementia/treatment/

  The aim of treatment for vascular dementia is to help: […] Treatment cannot cure vascular dementia or reverse damage. […] Your doctor may prescribe medicines to treat conditions contributing to your dementia. […] Some medicines can reduce the risk of blood clots and further strokes. […] Medicines such as donepezil (Aricept) or galantamine (Reminyl) are sometimes prescribed for vascular dementia. […] Your care team can recommend or organise supports for you to help make your everyday activities easier and more accessible. […] These include: occupational therapy to identify problems in everyday life, such as getting dressed […] psychological therapies, such as cognitive stimulation to improve memory, problem-solving and language […] Assistive technologies can make it easier for you to live at home. […] It can help to get in touch with a support group.

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