Materiały źródłowe

• #1

  https://www.orthobullets.com/hand/6054/basilar-thumb-arthritis

  Basilar Thumb Arthritis, also referred to as trapeziometacarpal (TMC) arthritis, is a common degenerative condition caused by attenuation of the volar beak and dorsoradial ligaments, leading to joint subluxation and cartilage degeneration of the trapeziometacarpal joint. This condition typically presents in elderly women with common symptoms of pain, crepitus, and loss of pinch/grip strength. […] Diagnosis is made clinically with tenderness to palpation over the thumb CMC joint, a painful CMC grind test, and radiographs of the hand showing osteoarthritis of the 1st CMC joint. […] Epidemiology: Incidence: common arthritis of the hand, 2nd only to DIP arthritis. […] Demographics: more common in women, seen in 25% of men and 40% of women aged 75 years old; however, radiographic evidence of TMC joint osteoarthritis is expected in normal aging among both sexes; high prevalence of disease in aging population suggests high degree of accommodation and coping with symptoms. […] thumb CMC arthritis is more common in Caucasians; hand OA is more common in native Americans than Caucasians/African Americans. […] Risk factors: female gender, increasing age, ligamentous laxity (Ehler-Danlos syndrome), theory currently not supported by experimental evidence.

• #2 Carpometacarpal Arthritis – WikiSM (Sports Medicine Wiki)

  https://wikism.org/Carpometacarpal_Arthritis

  Very common, affecting up 11% of men and 33% of women. […] Second most common arthritis of hand behind DIPJ.

• #3 Thumb Arthritis: Symptoms and Treatment | The Hand Society

  https://www.assh.org/handcare/condition/thumb-arthritis

  Thumb arthritis is the second most common type of arthritis in the hand; the most prevalent hand arthritis involves the last joint in each finger. […] Thumb arthritis is also known as basal joint arthritis. It is more common in women, though certainly men can develop this type of problem. […] There is a genetic predisposition in developing this arthritis condition. […] X-rays show that basal joint arthritis will generally get worse with time. The rate of the progression of arthritis varies from one person to another.

• #4 Trapeziometacarpal Osteoarthritis – Anatomy, Biomechan…

  https://ortopedia.com.pl/seo/article/162322/en

  Arthritis is the most common joint disease. […] The thumb is the most important digit of the hand and trapeziometacarpal osteoarthritis (carpometacarpal arthritis / CMC-1 arthritis) may significantly compromise functions of the entire hand. […] CMC-1 arthritis produces several non-specific symptoms, affecting mainly postmenopausal women. […] The risk of developing CMC-1 arthritis increases with age. […] This paper aims to present the most up-to-date knowledge about: (1) the anatomy and biomechanics of the trapeziometacarpal joint, (2) the epidemiology of CMC-1 arthritis and (3) its diagnosis. […] The authors believe that it may contribute to broadening knowledge about CMC-1 arthritis, optimizing the therapeutic process and improving care for patients with CMC-1 arthritis in Poland.

• #5 Trapeziometacarpal osteoarthritis – Wikipedia

  https://en.wikipedia.org/wiki/Trapeziometacarpal_osteoarthritis

  CMC OA is the most common form of OA affecting the hand. Dahaghin et al. showed that about 15% of women and 7% of men between 50 and 60 years of age develop CMC OA of the thumb. […] However, in about 65% of people older than 55 years, radiologic evidence of OA was present without any symptoms. Armstrong et al. reported a prevalence of 33% in postmenopausal women, of which one-third was symptomatic, compared to 11% in men older than 55 years. […] This shows CMC OA of the thumb is significantly more prevalent in women, especially in postmenopausal women, compared to men.

• #6 Thumb Carpometacarpal Arthritis: Classification and Management.

  https://epos.myesr.org/poster/esr/ecr2018/C-1183

  Thumb carpometacarpal (CMC) arthritis affects up to 25% of women and 10% of men with ages 50 years. […] Thumb CMC arthritis is a debilitating disease affecting more than 25% of postmenopausal women. […] The laxity of the anterior oblique ligament is one of the major contributors to osteoarthritis.

• #7 Basal joint arthritis presentation | PPT

  https://www.slideshare.net/slideshow/basal-joint-arthritis-presentation/32083988

  Epidemiology Most common site of osteoarthritis in the hand Most common site requiring surgery Most common in post-menopausal females 1:4 women will show radiographic degeneration Only ~ 20-30% symptomatic 8% with ST arthritis Only 1:12 men affected […] Epidemiology Armstrong, et al, J Hand Surg (Br), 1994 evaluated 143 post-menopausal women 25% had isolated basal thumb osteoarthritis of those with isolated CMC osteoarthritis, 28% complained of thumb pain […] Etiology No clear association with employment Repetitive motion suggests higher incidence Carpentry, manual labor Cow Milking (Seoane, 1997) Males with increased grip strength – increased radiographic changes (Chaisson, 2001) […] Etiology 1) Trauma – dislocation, fracture 2) Inammatory diseases – RA, gout 3) Idiopathic Osteoarthritis 4) Hypermobile States Moulton (2001) showed increased joint forces in TM joints with hyperextension laxity at the MCP joint

• #8 Prevalence of doctor-diagnosed thumb carpometacarpal joint osteoarthritis: an analysis of Swedish health care – PubMed

  https://pubmed.ncbi.nlm.nih.gov/24339432/

  Objective: While the prevalence of radiographic thumb carpometacarpal (CMC1) osteoarthritis (OA) is well-described, little is known about clinically symptomatic disease presenting to physicians for care. We sought to determine the prevalence of doctor-diagnosed CMC1 OA. […] The prevalence of doctor-diagnosed CMC1 OA in adults was estimated at 1.4% (2.2% in women and 0.62% in men). […] The clinically important prevalence of CMC1 OA is 3 to 4 times higher in women than men. By the end of 2012, more than 1 in 20 elderly women had consulted a physician for CMC1 OA over the last 15 years. The high prevalence of this subset of hand OA is a concern in an aging population.

• #9 Prevalence of Symptomatic Basilar Thumb Joint Osteoarthritis in the General Population – ACR Meeting Abstracts

  https://acrabstracts.org/abstract/prevalence-of-symptomatic-basilar-thumb-joint-osteoarthritis-in-the-general-population/

  Prevalence of symptomatic basilar thumb joint osteoarthritis in the general population […] While the radiographic prevalence of basilar thumb osteoarthritis (OA) is well described, little is known about whether this translates to clinically symptomatic arthritis. The purpose of this study is to determine the prevalence of physician-diagnosed thumb carpometacarpal (CMC) arthritis. […] The point prevalence of physician-diagnosed symptomatic OA of the basilar thumb joint in adults was estimated to 1.3% overall (2.0% in women and 0.57% in men). The prevalence peaked in women aged 65-74 with prevalence of 5.3%. The corresponding peak in men was in men aged 75-84 with a prevalence of 1.7%. […] In a well-defined population, the clinically important prevalence of basilar thumb OA is substantially higher in women than men, with peak prevalence in women between 60-79 years of age. Thumb base OA can have a large impact on function and activities of daily living, and the high prevalence in elderly women and men is a health and economic concern in an aging population.

• #10 Osteoarthritis of the thumb – First CMC joint – Ultrasound Guided Injections

  https://www.ultrasound-guided-injections.co.uk/osteoarthritis-thumb-first-cmc/

  Osteoarthritis is a progressive, degenerative condition caused when the thumb is exposed to prolonged periods of one or more of the above risk factors. […] A recent study revealed first CMC joint osteoarthritis is present in 2.2% of patients suffering from hand pain (Kwok et al, 2014). […] Many risk factors are associated with the onset of first CMC osteoarthritis and include: Age – Prevalence of first CMC joint osteoarthritis increases significantly after the age of 50 (Sonne-Holm et al, 2006). […] Women are at a higher risk of first CMC joint osteoarthritis than men (Sonne-Holm et al, 2006). […] Current evidence shows it is an effective alternative to corticosteroid injection for reducing pain and inflammation in arthritic joints.

• #11

  http://www.nccs.com.sg/news/defining-med/thumb-arthritis-pri-care

  Thumb arthritis is common with ageing. The most frequent site in the thumb is at the basal joint, also known as the first carpometacarpal joint (CMCJ). Most thumb base arthritis cases result from degenerative (wear and tear) conditions, where friction from the bones rubbing against each other causes the joint cartilage to wear away. It affects up to 10% of the middle-aged female population, with incidence increasing with age. […] General practitioners hold the key to the early identification and treatment of thumb base arthritis, with many cases able to be managed effectively in their care. […] General practitioners (GPs) play a vital role in the early identification and management of thumb CMCJ arthritis. While many cases can be managed conservatively, certain scenarios warrant referral to a hand surgeon for specialised care.

• #12 Thumb arthritis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/thumb-arthritis/symptoms-causes/syc-20378339

  Thumb arthritis commonly occurs with aging. […] Factors that can increase your risk of thumb arthritis include: […] Although osteoarthritis is the most common cause of thumb arthritis, rheumatoid arthritis can also affect the CMC joint, usually to a lesser extent than other joints of the hand.

• #13 Basal thumb arthritis

  https://pmc.ncbi.nlm.nih.gov/articles/PMC2599975/

  Basal thumb arthritis is a common condition seen in hand clinics across the United Kingdom and is often associated with other pathological conditions such as carpal tunnel syndrome and scaphotrapezial arthritis. […] The prevalence of basal thumb arthritis increases with age and is seen predominantly in postmenopausal women. The female:male ratio is 6:1. No conclusive environmental or genetic factors that lead to the expression of this disease have been identified. […] Basal thumb arthritis is a common problem that presents to hand clinics all over the UK. […] A detailed history and examination is necessary and is normally all that is needed to make the diagnosis. Radiographs are useful for confirming the diagnosis and staging the disease to plan for surgery.

• #14

  https://link.springer.com/article/10.1007/s12178-008-9022-7

  The purpose of this article is to outline the pathophysiology and epidemiology of arthritis of the base of the thumb. […] Approximately one in four women and one in twelve men will develop radiographic evidence of joint degeneration although not all will become symptomatic. Women with symptomatic involvement of the base of the thumb outnumber men by a ratio of 10-15:1. […] Racial differences have also been observed, especially between Asian and White populations. Postmortem studies in whites show a 50% rate of severe arthritis at the TM joint, whereas similar studies in the Japanese literature document an 8% rate of severe joint changes.

• #15 Arthritis – Wikipedia

  https://en.wikipedia.org/wiki/Arthritis

  Arthritis is predominantly a disease of the elderly, but children can also be affected by the disease. Arthritis is more common in women than men at all ages and affects all races, ethnic groups and cultures. In the United States, a CDC survey based on data from 2013 to 2015 showed 54.4 million (22.7%) adults had self-reported doctor-diagnosed arthritis, and 23.7 million (43.5% of those with arthritis) had arthritis-attributable activity limitation (AAAL). With an aging population, this number is expected to increase. Adults with co-morbid conditions, such as heart disease, diabetes, and obesity, were seen to have a higher than average prevalence of doctor-diagnosed arthritis (49.3%, 47.1%, and 30.6% respectively). […] Disability due to musculoskeletal disorders increased by 45% from 1990 to 2010. Of these, osteoarthritis is the fastest increasing major health condition. Among the many reports on the increased prevalence of musculoskeletal conditions, data from Africa are lacking and underestimated. A systematic review assessed the prevalence of arthritis in Africa and included twenty population-based and seven hospital-based studies. The majority of studies, twelve, were from South Africa. Nine studies were well-conducted, eleven studies were of moderate quality, and seven studies were conducted poorly. The results of the systematic review were as follows: Rheumatoid arthritis: 0.1% in Algeria (urban setting); 0.6% in Democratic Republic of Congo (urban setting); 2.5% and 0.07% in urban and rural settings in South Africa respectively; 0.3% in Egypt (rural setting), 0.4% in Lesotho (rural setting)

• #16 Products – Data Briefs – Number 497 – February 2024

  https://www.cdc.gov/nchs/products/databriefs/db497.htm

  In 2022, the age-adjusted prevalence of diagnosed arthritis in adults age 18 and older was 18.9%, with women (21.5%) more likely to have arthritis than men (16.1%). […] Arthritis increased with increasing age, from 3.6% in adults ages 18-34 to 53.9% in those age 75 and older. […] Black non-Hispanic, White non-Hispanic, and other and multiple-race non-Hispanic adults were more likely to have arthritis than Hispanic and Asian non-Hispanic adults. […] The prevalence of arthritis decreased with increasing family income, from 24.7% among those with family income less than 100% of the federal poverty level to 16.6% among those with family income at 400% of the federal poverty level or more. […] The percentage of adults with arthritis increased with decreasing urbanization level and varied by region.

• #17 Osteoarthritis of the hand | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/osteoarthritis-of-the-hand?lang=us

  Hand osteoarthritis is highly prevalent with women over the age of 50 most commonly affected. The prevalence on hand radiographs is estimated at ~50% (range 27-80%), although many of these may be asymptomatic with prevalence rates of symptomatic hand OA reported at ~15% (range 6-26%) with increased prevalence in older age groups. […] Major risk factors hand osteoarthritis includes age 40 years, female sex, positive family history, occupation (e.g. cotton picking, heavy manual labor, repetitive hand use), obesity, prior joint injury.

• #18 Familial Clustering and Genetic Analysis of Severe Thumb Carpometacarpal Joint Osteoarthritis in a Large Statewide Cohort | medRxiv

  https://www.medrxiv.org/content/10.1101/2022.03.03.22271851v1

  Objectives The objectives of this study are to 1) identify individuals that required surgery for thumb carpometacarpal osteoarthritis (CMCJ OA), 2) determine if CMCJ OA clusters in multigenerational families, 3) define the magnitude of familial risk of CMCJ OA, 4) identify risk factors associated with CMCJ OA and 5) identify rare genetic variants that segregate with familial CMCJ OA. […] We identified 550 pedigrees with excess clustering of severe CMCJ OA. The relative risk of developing CMCJ OA requiring surgical treatment was significantly elevated in first- and third-degree relatives of affected individuals, and significant associations with advanced age, female sex, obesity, and tobacco use were observed. […] Familial clustering of severe CMCJ OA was observed in a statewide population. Identification of a candidate gene indicates a genetic contribution to the etiology of the disease. Our data indicate the genetic and environmental factors contribute to the disease process, further highlighting the multifactorial nature of the disease. […] Severe CMCJ OA clusters in large, multigenerational families indicating a genetic contribution to the disease.

• #19 Occupational risk factors for thumb carpometacarpal joint osteoarthritis: a register-based study of construction workers | Occupational & Environmental Medicine

  https://oem.bmj.com/content/early/2025/02/04/oemed-2024-109949

  Objectives The study investigated the association between occupational biomechanical risk factors and the occurrence of thumb carpometacarpal joint osteoarthritis (CMC1 OA) in construction workers. […] The results show an increased risk of developing CMC1 OA for work involving high grip force, pinch grip, repetitive wrist movements, hand-held tool use, heavy lifting and hand-arm vibration and highlight a possible potential of preventing CMC1 OA by reducing these exposures. […] This study adds to the sparse literature on the associations between occupational biomechanical exposure and CMC1 OA. The results highlight a possible potential of preventing CMC1 OA by reducing handloading, repetitive wrist movements and exposure to HAV.

• #20 DISTRACT — Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences

  https://www.ndorms.ox.ac.uk/research/clinical-trials/current-trials-and-studies/distract

  Osteoarthritis (OA) is a process that occurs with aging and describes the weakening of the joint cartilage. Thumb arthritis is the second most common type of arthritis in the hand. The joint at the base of the thumb is commonly affected in those living with hand osteoarthritis. Thumb base Osteoarthritis (TBOA) causes pain and loss of function. […] Approximately 5,000 patients in the UK and 100,000 patients in the USA undergo surgery for end stage disease each year. […] This project meets four of the ten priorities identified in the James Lind Alliance Priority Setting Partnership for hand conditions. These include finding alternatives to surgery, building better evidence, and comparing surgery with non-surgical treatments.

• #21 Basal joint arthritis presentation | PPT

  https://www.slideshare.net/slideshow/basal-joint-arthritis-presentation/32083988

  Etiology 5) TM Instability Acute: severe trauma (complete dislocation) Chronic: can be caused by recurrent stress or overuse more common often seen in young to middle-aged women […] Treatment Options Depends on stage of disease as well as degree of the patients discomfort ! Conservative: Rest, NSAIDs, steroid injections, splinting with thumb in abduction (Stage I) ! Surgical: Multiple surgical treatment methods (more advanced stages) […] Conservative Treatment Swigart, et al, J of Hand Surg, 1999 Evaluated 130 thumbs treated with 6 weeks of splinting Stage I/II: 76% improvement Stage III/IV: 54% improvement Overall splinting is well-tolerated effective protocol to diminish, but not eliminate the symptoms of basal joint OA […] Surgical Costs Metacarpal Osteotomy = $2150 LRTI = $5665 Arthroplasty = $7260

• #22

  https://journals.lww.com/jbjsjournal/fulltext/2023/12060/long_term_outcomes_of_nonsurgical_treatment_of.2.aspx

  While guidelines advise initial nonsurgical treatment to potentially avoid surgery, the actual long-term conversion to surgery has been poorly described. […] We found no clinically relevant change in pain and limitations in ADL between 12 months and 5 years following nonsurgical treatment for CMC-1 OA. […] Our findings suggest that the improvement after nonsurgical treatment as measured in the first 12 months after treatment is sustainable. […] Secondary outcomes at 5 years of follow-up indicated relatively high satisfaction with treatment results, and only 22% had converted to surgery at a median follow-up of 7.0 years. […] Our finding that only 22% converted to surgery is comparable with rates in other studies with shorter follow-up durations. […] The findings that the conversion rate at approximately 2 years is comparable with the conversion rate at 5 years indicates that few patients undergo surgery once the positive treatment effect has been achieved, which further supports nonsurgical treatment as a first treatment choice.

• #23 (PDF) Radiographic thumb osteoarthritis: frequency, patterns and associations with pain and clinical assessment findings in a community-dwelling population

  https://www.academia.edu/90902791/Radiographic_thumb_osteoarthritis_frequency_patterns_and_associations_with_pain_and_clinical_assessment_findings_in_a_community_dwelling_population?uc-sb-sw=69892499

  Objectives. The aim of this study was to investigate: (i) the frequency and patterns of radiographic OA (ROA) in the thumb joints; and (ii) associations between thumb ROA and the clinical characteristics of thumb OA in older adults with hand pain or problems. […] The first CMC and thumb IP joints were the hand joints most frequently affected with ROA. […] Multivariable analyses showed that older age, thumb pain, thenar muscle wasting and presence of nodes, deformity or enlargement best determined the presence of thumb ROA. […] The presence of thumb ROA was strongly associated with a combination of older age, thumb pain and clinical features of OA. […] The objectives of this study were to determine relationships of ROA at different hand joints, use the findings to define radiographic subgroups and investigate their associations with pain and function.

• #24

  https://journals.lww.com/jbjsjournal/fulltext/2023/12060/long_term_outcomes_of_nonsurgical_treatment_of.2.aspx

  Osteoarthritis (OA) of the thumb carpometacarpal joint (CMC-1) is a common disorder with a symptomatic prevalence of 7% for females and 2% for males 50 years of age. […] Because of the aging population, the number of patients with CMC-1 OA is expected to increase. […] Most guidelines for the management of CMC-1 OA advise starting with nonsurgical treatment, such as the use of an orthosis, corticosteroid injections, analgesics, exercise therapy, or a combination of these treatments. […] Although short-term effectiveness has been demonstrated for the combination of exercise therapy and orthosis use, the long-term effects are unknown. […] Because of the chronic nature of CMC-1 OA, knowledge of the long-term outcomes is needed to provide patients and clinicians with greater insight into the durability of nonoperative management.

• #25 Thumb arthritis can be a real pain for older adults – The University of Kansas Health System

  https://kutopeka.com/2022/03/23/thumb-arthritis-can-be-a-real-pain-for-older-adults/

  Thumb arthritis can be a real pain for older adults. […] People who feel pain in their dominant hand when opening a jar or turning a doorknob may be developing thumb arthritis. […] Unfortunately, it is difficult to prevent thumb arthritis as it generally results from wear and tear of the joint surface over time. […] While this condition can affect men, it occurs most commonly in women between the ages of 40-70 years. […] A patient should see a doctor for this problem if symptoms happen daily and limit their abilities to do things without pain. X-rays are typically obtained for diagnosis confirmation and are helpful to assist with monitoring the progression of the disease over time.

Zobacz więcej