Materiały źródłowe

• #1 What Is Delayed Sleep Phase Syndrome?

  https://www.verywellhealth.com/delayed-sleep-phase-syndrome-overview-4585048

  Delayed sleep phase syndrome (DSPS) occurs in people whose circadian rhythms (cyclical sleep patterns) are set two hours or more later than in most people. […] Delayed sleep phase syndrome also is closely linked with attention deficit hyperactivity disorder (ADHD), with some studies suggesting a higher risk of heart problems in these people. […] There seems to be a genetic predisposition towards developing delayed sleep phase syndrome. Some of this science is understood. For example, a mutation in the CRY1 gene alters the human circadian clock, delaying sleep by two to two-and-a-half hours compared to non-carriers. […] Current research shows a hereditary component in 40% to 50% of „clock types” whether you are a morning person or a night owl. […] Beyond genetic programming, there are environmental factors that may unmask the condition. Most importantly, light has powerful effects on the timing of the circadian system. It may provoke the delay in sleep timing. However, it may also be used to correct the condition.

• #2 Delayed sleep phase disorder – Wikipedia

  https://en.wikipedia.org/wiki/Delayed_sleep_phase_disorder

  Delayed sleep phase disorder (DSPD), more often known as delayed sleep phase syndrome and also as delayed sleepwake phase disorder, is the delaying of a person’s circadian rhythm (biological clock) compared to those of societal norms. […] The disorder affects the timing of biological rhythms including sleep, peak period of alertness, core body temperature, and hormonal cycles. […] There may be a genetic component to the syndrome. […] DSPD is a disorder of the body’s timing system—the biological clock. Individuals with DSPD might have an unusually long circadian cycle, might have a reduced response to the resetting effect of daylight on the body clock, and/or may respond overly to the delaying effects of evening light and too little to the advancing effect of light earlier in the day.

• #3 How to treat Delayed Sleep Phase Syndrome — Sleep Cycle

  https://www.sleepcycle.com/sleep-disorders/identifying-and-treating-delayed-sleep-phase-disorder/

  This syndrome describes a glitch in the bodys Circadian rhythm that causes the delay of a sleep pattern by two or more hours. […] Certain medical conditions, such as depression and anxiety, can increase the risk of developing DSPS. […] Genetics may also play a role in the development of DSPS. Research has found that certain genetic variations may be associated with an increased risk of developing DSPS. […] Melatonin supplements can be used to help regulate the sleep-wake cycle and shift the bodys natural sleep pattern. […] Delayed sleep phase syndrome and insomnia are two distinct conditions, and they cannot be used interchangeably. […] Individuals with DSPS do not intend to stay up late, but their internal clock delays their sleep, making it challenging to fall asleep and wake up at conventional times.

• #4

  https://olaben.com/blogs/olaben-blog/understanding-delayed-sleep-phase-syndrome-causes-symptoms-and-treatment?srsltid=AfmBOopJM6Yy1-Tu4d8UTGqut-VN3CZdnOiq1gBNHBVBHJiRxCBZ07qk

  Delayed Sleep Phase Syndrome (DSPS) is a sleep disorder characterized by a persistent delay in the timing of sleep-wake cycles. […] While the exact causes of DSPS are not fully understood, research has shed light on several factors that may contribute to its development. […] One significant factor that has been identified in the development of DSPS is genetics. Studies have shown that certain genetic variants can influence the functioning of the internal clock, also known as the circadian rhythm. […] Furthermore, researchers have found that certain genes involved in the production of melatonin, a hormone that helps regulate sleep, may also play a role in DSPS. […] Environmental factors can also have a significant impact on the development and perpetuation of DSPS. […] One such factor is exposure to bright lights at inappropriate times.

• #5 Delayed Sleep-Wake Phase – Sleep Education by the AASM

  https://sleepeducation.org/sleep-disorders/delayed-sleep-wake-phase/

  Delayed sleep-wake phase disorder (DSP) is a circadian rhythm disorder. It consists of a typical sleep pattern that is “delayed” by two or more hours from societal norms. This delay occurs when your internal sleep clock (circadian rhythm) is shifted later at night and later in the morning. […] A family history of DSP is common in about 40% of people with the disorder and there is likely a genetic component. Some environmental factors may also be involved. Both a lack of exposure to morning sunlight and too much exposure to bright light in the evening may increase symptoms of DSP. […] Strategically timed low dose melatonin use has been shown to be an effective treatment option in teens, and it may be somewhat effective in adults. Melatonin is a hormone that is widely available in supplement form. The hormone is naturally produced by your body and plays an important role in sleep. It helps regulate your sleep-wake cycle by signaling to your body when the time for sleep is approaching.

• #6 What Is Delayed Sleep Phase Syndrome?

  https://www.verywellhealth.com/delayed-sleep-phase-syndrome-overview-4585048

  Delayed sleep phase syndrome (DSPS) occurs in people whose circadian rhythms (cyclical sleep patterns) are set two hours or more later than in most people. […] Delayed sleep phase syndrome also is closely linked with attention deficit hyperactivity disorder (ADHD), with some studies suggesting a higher risk of heart problems in these people. […] There seems to be a genetic predisposition towards developing delayed sleep phase syndrome. Some of this science is understood. For example, a mutation in the CRY1 gene alters the human circadian clock, delaying sleep by two to two-and-a-half hours compared to non-carriers. […] Current research shows a hereditary component in 40% to 50% of „clock types” whether you are a morning person or a night owl. […] Beyond genetic programming, there are environmental factors that may unmask the condition. Most importantly, light has powerful effects on the timing of the circadian system. It may provoke the delay in sleep timing. However, it may also be used to correct the condition.

• #7 Scientists discover how a common mutation leads to 'night owl’ sleep disorder | ScienceDaily

  https://www.sciencedaily.com/releases/2020/10/201027105354.htm

  People with delayed sleep phase disorder are unable to fall asleep until late at night (often after 2 a.m.) and have difficulty getting up in the morning. […] In 2017, scientists discovered a surprisingly common mutation that causes this sleep disorder by altering a key component of the biological clock that maintains the body’s daily rhythms. […] A shortened clock cycle causes people to go to sleep and wake up earlier than normal (the „morning lark” effect), while a longer clock cycle makes people stay up late and sleep in (the „night owl” effect). […] The genetic variant identified in the 2017 study, however, was found in around one in 75 people of European descent. […] This genetic marker is really widespread. […] We still have a lot to understand about the role of lengthened clock timing in delayed sleep onset, but this one mutation is clearly an important cause of late night behavior in humans.

• #8 Scientists discover how a common mutation leads to 'night owl’ sleep disorder | ScienceDaily

  https://www.sciencedaily.com/releases/2020/10/201027105354.htm

  The mutation affects a protein called cryptochrome, one of four main clock proteins. […] The cryptochrome mutation causes a small segment on the „tail” of the protein to get left out, and Partch’s lab found that this changes how tightly cryptochrome binds to the CLOCK:BMAL1 complex. […] Without it, cryptochrome binds more tightly and stretches out the length of the clock each day. […] Partch’s lab is currently doing just that, conducting screening assays to identify molecules that bind to the pocket in the clock’s molecular complex. „We know now that we need to target that pocket to develop therapeutics that could shorten the clock for people with delayed sleep phase disorder,” she said.

• #9 How a Genetic Mutation Causes Delayed Sleep Phase Disorder | Sleep Review

  https://sleepreviewmag.com/sleep-disorders/circadian-rhythm-disorders/delayed-phase/genetic-mutation-causes-delayed-phase-disorder/

  A new study by researchers at UC Santa Cruz shows how a genetic mutation throws off the timing of the biological clock, causing delayed sleep phase disorder. […] In 2017, scientists discovered a surprisingly common mutation that causes this sleep disorder by altering a key component of the biological clock that maintains the body’s daily rhythms. […] Genetic variations that change the clock proteins can alter the timing of the clock and cause sleep phase disorders. […] The genetic variant identified in the 2017 study, however, was found in around one in 75 people of European descent. […] This genetic marker is really widespread, Partch says. We still have a lot to understand about the role of lengthened clock timing in delayed sleep onset, but this one mutation is clearly an important cause of late night behavior in humans.

• #10 Delayed Sleep Phase Disorder (Delayed Sleep Phase Syndrome) | The Better Sleep Clinic

  https://thebettersleepclinic.com/sleep-disorders/delayed-sleep-phase-disorder

  Several genetic polymorphisms have been associated with an increased risk of developing DSWPD: Variations in the human Period 3 (hPER3) gene (Jones et al., 2013) […] The widespread use of artificial lighting and increased time spent indoors have diminished exposure to natural light cycles. This reduction in environmental zeitgebers (time giving signals to the internal master circadian clock) can weaken the entrainment of the circadian system, potentially increasing susceptibility to DSWPD (Wright et al., 2013). […] The prevalence of light-emitting electronic devices has introduced a new risk factor for circadian disruption. Evening exposure to blue light from screens can suppress melatonin production and delay sleep onset in those with more sensitive eyes exacerbating DSWPD symptoms (Micic et al., 2016).

• #11 Delayed sleep phase disorder – Wikipedia

  https://en.wikipedia.org/wiki/Delayed_sleep_phase_disorder

  In most cases, it is not known what causes the abnormality in the biological clocks of DSPD patients. DSPD tends to run in families, and a growing body of evidence suggests that the problem is associated with the hPer3 (human period 3) gene and CRY1 gene. […] Researchers in 2017 linked DSPD to at least one genetic mutation.

• #12 Delayed sleep-wake phase disorder

  https://researchfeatures.com/delayed-sleep-wake-phase-disorder/

  Delayed sleep-wake phase disorder (DSWPD) is a circadian rhythm disorder, characterised by a late onset of sleep and wakefulness compared to conventional times or a night owl preference. The exact cause is unknown but a combination of genetic and environmental factors (lifestyle, such as shift work) has been suggested. […] The exact cause of DSWPD has remained elusive. Researchers have hypothesised that both genetic and environmental factors play a role in initiating and exacerbating this condition. A family history with the same condition has been found in approximately 40% of individuals. Polymorphism in the circadian clock gene hPer3, human leukocyte antigen, and Clock are found to be associated with DSWPD onset and progression. A 2017 study published in Cell identified a gene involved in the circadian clock, CRY1, to play a role in DSWPD. A gain-of-function mutation leads to increased CRY1 protein expression and inhibition of target genes: Clock and BMAL1. Altogether, it is associated with increased period of molecular circadian rhythms in cells and delayed sleep onset.

• #13 Delayed sleep-wake phase disorder | MedLink Neurology

  https://www.medlink.com/articles/delayed-sleep-wake-phase-disorder

  Delayed sleep-wake phase disorder is due to a misalignment between the body’s endogenous circadian rhythm and the social environment. […] Proposed causes for this delay include decreased response to the phase-advancing effect of morning light, an increased responsiveness to the delaying effects of evening light, and a longer than average circadian cycle. […] Although the etiology is unknown in most cases, studies show a genetic predisposition in familial cases due to polymorphisms in circadian clock genes. […] Delayed sleep-wake phase disorder is theorized to develop due to multiple possible factors, including decreased response to the phase-advancing effect of morning light, an increased responsiveness to the delaying effects of evening light, and a longer than average circadian cycle. […] Susceptibility to delayed sleep-wake phase disorder may involve polymorphisms of the circadian gene Per3 and its promoter region. […] Behavioral factors such as late-night light exposure through television, computer screens, and smartphones also play an important role.

• #14 Delayed Sleep Phase Disorder (Delayed Sleep Phase Syndrome) | The Better Sleep Clinic

  https://thebettersleepclinic.com/sleep-disorders/delayed-sleep-phase-disorder

  Delayed Sleep-Wake Phase Disorder (DSWPD) arises from a complex interaction of biological, environmental, and behavioral factors that influence fall asleep and wake times. At present, these underlying mechanisms are not fully understood, however some factors have been identified. […] A primary cause of DSWPD is a significant delay in the individual’s circadian rhythm (governed by an internal clock in the human brain). This delay is evidenced by later timing of physiological markers such as dim light melatonin onset (DLMO) and core body temperature minimum (Tmin) (Micic et al., 2016). […] Many individuals with DSWPD have an endogenous (naturally occurring) circadian period or length (known as tau) that is longer than 24 hours. This can range from slightly over 24 hours to as long as 24.64 hours (Micic et al., 2016).

• #15 Delayed Sleep Phase Disorder (Delayed Sleep Phase Syndrome) | The Better Sleep Clinic

  https://thebettersleepclinic.com/sleep-disorders/delayed-sleep-phase-disorder

  Studies have suggested that individuals with DSWPD may be more sensitive to the phase-delaying effects of light exposure in the evening. This heightened sensitivity to light can magnify circadian delays, pushing the time an individual falls asleep later (unable to fall asleep) leading and individual to sleep later, making it more challenging to maintain a conventional sleep schedule (Aoki et al., 2001). […] Some research indicates that people with DSWPD may be less responsive to the phase-advancing effects of morning light that bring forward the time to wake up, and support waking earlier in the morning and earlier times to fall asleep in the evening. This diminished sensitivity could impair the natural resetting of the circadian system that typically occurs with early light exposure (Micic et al., 2016).

• #16 Delayed Sleep Phase Disorder (Delayed Sleep Phase Syndrome) | The Better Sleep Clinic

  https://thebettersleepclinic.com/sleep-disorders/delayed-sleep-phase-disorder

  Studies have suggested that individuals with DSWPD may be more sensitive to the phase-delaying effects of light exposure in the evening. This heightened sensitivity to light can magnify circadian delays, pushing the time an individual falls asleep later (unable to fall asleep) leading and individual to sleep later, making it more challenging to maintain a conventional sleep schedule (Aoki et al., 2001). […] Some research indicates that people with DSWPD may be less responsive to the phase-advancing effects of morning light that bring forward the time to wake up, and support waking earlier in the morning and earlier times to fall asleep in the evening. This diminished sensitivity could impair the natural resetting of the circadian system that typically occurs with early light exposure (Micic et al., 2016).

• #17 Delayed sleep phase | Beacon Health System

  https://www.beaconhealthsystem.org/library/diseases-and-conditions/delayed-sleep-phase?content_id=CON-20313606

  Delayed sleep phase is caused by a person’s internal clock being out of sync with the environment. Your internal clock lets you know when it’s time to sleep and when it’s time to wake. Known as circadian rhythm, your internal clock is on a 24-hour cycle. Cues in the environment influence the sleep-wake cycle. These cues include light, darkness, eating and physical activity. […] The exact cause of delayed sleep phase isn’t known. But circadian rhythms can be delayed in teenagers for biological reasons. Staying up late to do homework, watch TV or use the internet can make the sleep delay worse.

• #18 Delayed sleep phase disorder – Wikipedia

  https://en.wikipedia.org/wiki/Delayed_sleep_phase_disorder

  Delayed sleep phase disorder (DSPD), more often known as delayed sleep phase syndrome and also as delayed sleepwake phase disorder, is the delaying of a person’s circadian rhythm (biological clock) compared to those of societal norms. […] The disorder affects the timing of biological rhythms including sleep, peak period of alertness, core body temperature, and hormonal cycles. […] There may be a genetic component to the syndrome. […] DSPD is a disorder of the body’s timing system—the biological clock. Individuals with DSPD might have an unusually long circadian cycle, might have a reduced response to the resetting effect of daylight on the body clock, and/or may respond overly to the delaying effects of evening light and too little to the advancing effect of light earlier in the day.

• #19 Delayed Sleep Phase Syndrome Symptoms And Causes

  https://welevelupfl.com/behavioral-health/delayed-sleep-phase-syndrome/

  Circadian Rhythm Regulation: DSPS is related to a disruption in the body’s circadian rhythm, the internal biological clock that regulates the sleep-wake cycle. […] Delayed Melatonin Release: Melatonin is a hormone that helps regulate sleep-wake cycles. People with DSPS may experience delayed release of melatonin in the evening, contributing to their difficulty falling asleep at conventional bedtimes. […] Developmental Changes: Adolescents and young adults are more susceptible to DSPS due to the natural delay in circadian rhythms that occurs during these life stages. […] Psychological Factors: Psychological factors like stress, anxiety, and depression can exacerbate sleep disorders, including DSPS. […] Social and Lifestyle Factors: Modern work and social demands often require adherence to early schedules, which can be particularly challenging for individuals with DSPS. […] Delayed Light Exposure in the Morning: Insufficient exposure to natural morning light, which helps reset the circadian rhythm, can contribute to a delayed sleep-wake cycle.

• #20 Delayed Sleep Phase Disorder (DSPS): Symptoms, Causes and Treatments

  https://www.clmsleep.com/delayed-sleep-phase-disorder/

  Circadian Rhythm Disruption: DSPD results from an intrinsic clock that runs slow relative to the 24-hour day. This causes a loss of proper phase relation between internal rhythm and some environmental cues, like the light-dark cycle and social routine. […] Melatonin Production Disorders: Melatonin, a clock-regulating hormonal agent whose role in DSPD is central has increasingly been recognized of late. Patients sometimes demonstrate delayed or blunted circadian melatonin rhythms, or reduced melatonin sensitivity. These changes impede the initiation and maintenance of sleep at typical hours. […] Light Exposure at Night: In the modern way of living, exposure for long hours to artificial sources of light is inevitable. This exposure mostly comes from blue light that emanates from electronic devices like smartphones and computers, is inevitable. This exposure completely reduces the production of melatonin hence making a person get sleep later than expected.

• #21 Delayed sleep phase disorder | Healthify

  https://healthify.nz/health-a-z/d/delayed-sleep-phase-disorder

  Delayed sleep phase disorder (DSPD) is a sleep problem where your body’s internal clock (24 hour circadian rhythm) is shifted by up to 2 hours or more, causing problems with falling asleep and waking up at a normal time. […] DSPD is thought to happen when your internal clock (circadian rhythm) is out of sync with the environment. Your circadian rhythm is on a 24-hour cycle and lets you know when it’s time to sleep and when it’s time to wake. Cues in the environment (eg, light and darkness, eating and physical activity) influence the sleep-wake cycle. […] With teenagers, DSPD may be partly due to biological reasons as the onset of the melatonin hormone production begins on average about an hour later in teens than adults. Staying up late to do homework, watch TV, play online games or use the internet will make the sleep delay worse.

• #22 Delayed Sleep-Wake Phase Disorder in Teens (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/delayed-sleep-teens.html

  The cause of DSWPD isnt clear, but several things can play a role: […] The sleep-wake cycle (circadian rhythm) tends to shift later during puberty. This means the brain releases melatonin (a hormone that tells the body to get ready for sleep) later in the evening than it would for a younger child or older adult. […] DSWPD can run in families, meaning it could be genetic. A teen may be more likely to develop DSWPD if a parent had it. […] Other things that can raise the risk of having DSWPD include working night shifts, traveling across time zones, and having too much caffeine.

• #23 Delayed Sleep Phase Syndrome Symptoms And Causes

  https://welevelupfl.com/behavioral-health/delayed-sleep-phase-syndrome/

  Causes of Delayed Sleep Phase Disorder: Genetic predisposition: Family history of sleep disorders or altered circadian rhythms. Environmental factors: Exposure to light and darkness can impact the body’s internal clock. Developmental factors: Adolescents and young adults are more commonly affected, as circadian rhythms naturally shift later during these life stages. […] The exact causes of Delayed Sleep Phase Syndrome (DSPS), also known as Delayed Sleep-Wake Phase Disorder, are not fully understood. However, researchers believe that a combination of genetic, biological, and environmental factors contribute to the development of this sleep disorder. […] Genetic Predisposition: There is evidence to suggest that genetics plays a significant role in DSPS. Family history of sleep disorders or altered circadian rhythms can increase the likelihood of an individual developing DSPS.

• #24 Delayed Sleep Phase Syndrome: Symptoms, Causes, and More

  https://www.health.com/delayed-sleep-phase-syndrome-8575662

  Delayed sleep phase syndrome occurs when your body’s circadian rhythm is out of sync with your environment. Your circadian rhythm is a biological clock that lets your body know when to sleep and when to wake up. Environmental factors (like how light or dark it is outside) and certain hormones in your body (such as melatonin and cortisol) can also influence your circadian rhythm. […] Currently, researchers are unsure why people with DSPS experience changes in their sleep-wake cycle. However, some factors that can contribute to a misaligned internal clock include: […] Having a family history of DSPS […] Not getting enough sunlight during the day […] Living with mental health conditions like depression and obsessive-compulsive disorder (OCD) […] Undergoing physical and hormonal changes during and after puberty […] Experiencing low levels of melatonin, a hormone that helps your body induce sleep.

• #25 Delayed Sleep-Wake Phase Disorder | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/delayed-sleep-wake-phase-disorder

  Schedule changes, such as early school start times in high school, can cause a teen to get chronically insufficient sleep. […] Sports practices late in the day and caffeine consumption can lead to delayed sleep onset. […] Use of electronic devices, specifically those that emit blue light, like TVs, computers, smartphones, and e-readers, before bed may suppress the release of melatonin, the body’s biological signal for sleep. […] Lack of exposure to morning light (which suppresses melatonin and helps you wake up) also contributes to DSWPD.

• #26 Delayed Sleep Phase Disorder (Delayed Sleep Phase Syndrome) | The Better Sleep Clinic

  https://thebettersleepclinic.com/sleep-disorders/delayed-sleep-phase-disorder

  Several genetic polymorphisms have been associated with an increased risk of developing DSWPD: Variations in the human Period 3 (hPER3) gene (Jones et al., 2013) […] The widespread use of artificial lighting and increased time spent indoors have diminished exposure to natural light cycles. This reduction in environmental zeitgebers (time giving signals to the internal master circadian clock) can weaken the entrainment of the circadian system, potentially increasing susceptibility to DSWPD (Wright et al., 2013). […] The prevalence of light-emitting electronic devices has introduced a new risk factor for circadian disruption. Evening exposure to blue light from screens can suppress melatonin production and delay sleep onset in those with more sensitive eyes exacerbating DSWPD symptoms (Micic et al., 2016).

• #27 Complete Sleep Solutions | Delayed Sleep Phase Syndrome (DSPS)

  http://completesleep.crammaze.com/Delayed_sleep_phase_syndrome_(DSPS).php

  Delayed sleep phase syndrome (DSPS) is a disorder in which a persons sleep is delayed by 2 or more hours beyond the socially acceptable or conventional bedtime. […] The exact cause of this disorder is not completely known. However, approximately 7% to 16% of adolescents have DSPS, making it a common disorder. Scientists think DSPS may be an exaggerated reaction to the normal shift in the internal clocks that is seen in adolescents after puberty. […] It is important to understand that this is not deliberate behavior, but that certain habits can make this condition worse. DSPS most commonly occurs during adolescence, but cases have been reported during childhood.

• #28

  https://olaben.com/blogs/olaben-blog/understanding-delayed-sleep-phase-syndrome-causes-symptoms-and-treatment?srsltid=AfmBOopJM6Yy1-Tu4d8UTGqut-VN3CZdnOiq1gBNHBVBHJiRxCBZ07qk

  Delayed Sleep Phase Syndrome (DSPS) is a sleep disorder characterized by a persistent delay in the timing of sleep-wake cycles. […] While the exact causes of DSPS are not fully understood, research has shed light on several factors that may contribute to its development. […] One significant factor that has been identified in the development of DSPS is genetics. Studies have shown that certain genetic variants can influence the functioning of the internal clock, also known as the circadian rhythm. […] Furthermore, researchers have found that certain genes involved in the production of melatonin, a hormone that helps regulate sleep, may also play a role in DSPS. […] Environmental factors can also have a significant impact on the development and perpetuation of DSPS. […] One such factor is exposure to bright lights at inappropriate times.

• #29

  https://olaben.com/blogs/olaben-blog/understanding-delayed-sleep-phase-syndrome-causes-symptoms-and-treatment?srsltid=AfmBOopJM6Yy1-Tu4d8UTGqut-VN3CZdnOiq1gBNHBVBHJiRxCBZ07qk

  In addition, irregular sleep schedules can disrupt the natural sleep-wake cycle. […] Lifestyle habits and practices can significantly impact the severity and persistence of DSPS symptoms. […] Understanding the various factors that contribute to the development of DSPS is crucial in developing effective treatment strategies.

• #30 Delayed Sleep-Wake Phase Disorder | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/delayed-sleep-wake-phase-disorder

  Schedule changes, such as early school start times in high school, can cause a teen to get chronically insufficient sleep. […] Sports practices late in the day and caffeine consumption can lead to delayed sleep onset. […] Use of electronic devices, specifically those that emit blue light, like TVs, computers, smartphones, and e-readers, before bed may suppress the release of melatonin, the body’s biological signal for sleep. […] Lack of exposure to morning light (which suppresses melatonin and helps you wake up) also contributes to DSWPD.

• #31 Delayed Sleep-Wake Phase Disorder | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/delayed-sleep-wake-phase-disorder

  Schedule changes, such as early school start times in high school, can cause a teen to get chronically insufficient sleep. […] Sports practices late in the day and caffeine consumption can lead to delayed sleep onset. […] Use of electronic devices, specifically those that emit blue light, like TVs, computers, smartphones, and e-readers, before bed may suppress the release of melatonin, the body’s biological signal for sleep. […] Lack of exposure to morning light (which suppresses melatonin and helps you wake up) also contributes to DSWPD.

• #32 Delayed Sleep-Wake Phase Disorder | Boston Children’s Hospital

  https://www.childrenshospital.org/conditions/delayed-sleep-wake-phase-disorder

  Schedule changes, such as early school start times in high school, can cause a teen to get chronically insufficient sleep. […] Sports practices late in the day and caffeine consumption can lead to delayed sleep onset. […] Use of electronic devices, specifically those that emit blue light, like TVs, computers, smartphones, and e-readers, before bed may suppress the release of melatonin, the body’s biological signal for sleep. […] Lack of exposure to morning light (which suppresses melatonin and helps you wake up) also contributes to DSWPD.

• #33

  https://www.aurorahealthcare.org/services/sleep-disorders/delayed-sleep-phase-syndrome

  Delayed sleep phase syndrome affects your body’s natural sleep-wake cycle. If you have delayed sleep phase syndrome, your natural sleep pattern is delayed by two or more hours compared to conventional sleep times. […] The exact cause of delayed sleep phase disorder is not entirely understood, but several factors may contribute to its development. Genetics can play a significant role, as delayed sleep phase syndrome often runs in families. Environmental factors, such as exposure to light at night, can also impact your circadian rhythm. Lifestyle habits such as irregular sleep patterns and inconsistent bedtimes can make the condition worse. In some cases, underlying medical or psychiatric conditions may be linked to delayed sleep phase syndrome. […] Theres a notable association between delayed sleep phase syndrome and attention deficit hyperactivity disorder (ADHD). Many individuals with ADHD experience sleep disorders, including delayed sleep phase syndrome.

• #34 Delayed sleep-wake phase disorder | MedLink Neurology

  https://www.medlink.com/articles/delayed-sleep-wake-phase-disorder

  Delayed sleep-wake phase disorder is due to a misalignment between the body’s endogenous circadian rhythm and the social environment. […] Proposed causes for this delay include decreased response to the phase-advancing effect of morning light, an increased responsiveness to the delaying effects of evening light, and a longer than average circadian cycle. […] Although the etiology is unknown in most cases, studies show a genetic predisposition in familial cases due to polymorphisms in circadian clock genes. […] Delayed sleep-wake phase disorder is theorized to develop due to multiple possible factors, including decreased response to the phase-advancing effect of morning light, an increased responsiveness to the delaying effects of evening light, and a longer than average circadian cycle. […] Susceptibility to delayed sleep-wake phase disorder may involve polymorphisms of the circadian gene Per3 and its promoter region. […] Behavioral factors such as late-night light exposure through television, computer screens, and smartphones also play an important role.

• #35 Delayed Sleep Phase Syndrome: Causes, Symptoms & Treatments

  https://www.healthline.com/health/sleep-deprivation/delayed-sleep-phase-syndrome

  Delayed sleep phase syndrome (DSPS) is a type of circadian rhythm sleep disorder. […] While the exact cause of DSPS isn’t known, it’s often associated with several factors. […] If you have a close relative with DSPS, you have a higher chance of developing the condition. Forty percent of people with DSPS have a family history of the disorder. […] During adolescence, the body’s 24-hour sleep cycle becomes longer, which requires later sleep and wake times. […] DSPS is linked to conditions like depression, anxiety, attention deficit hyperactivity disorder, and obsessive-compulsive disorder. […] DSPS affects 10 percent of people with chronic insomnia. […] DSPS symptoms can get worse if you don’t get enough light exposure in the morning. Symptoms might also increase if you’re exposed to too much light at night.

• #36

  https://www.aurorahealthcare.org/services/sleep-disorders/delayed-sleep-phase-syndrome

  Delayed sleep phase syndrome affects your body’s natural sleep-wake cycle. If you have delayed sleep phase syndrome, your natural sleep pattern is delayed by two or more hours compared to conventional sleep times. […] The exact cause of delayed sleep phase disorder is not entirely understood, but several factors may contribute to its development. Genetics can play a significant role, as delayed sleep phase syndrome often runs in families. Environmental factors, such as exposure to light at night, can also impact your circadian rhythm. Lifestyle habits such as irregular sleep patterns and inconsistent bedtimes can make the condition worse. In some cases, underlying medical or psychiatric conditions may be linked to delayed sleep phase syndrome. […] Theres a notable association between delayed sleep phase syndrome and attention deficit hyperactivity disorder (ADHD). Many individuals with ADHD experience sleep disorders, including delayed sleep phase syndrome.

• #37 Reddit – The heart of the internet

  https://www.reddit.com/r/adhdwomen/comments/y6m6bg/delayed_sleep_phase_syndrome/

  Those with ADHD often deal with DSPS, which basically spells out to our circadian rhythm is thrown off by 2+ hours. Which means you don’t get tired until like after midnight and don’t naturally want to wake up until late morning or early afternoon. […] If we slept the way our bodies wanted to, we would deal with much less consequences of being tired during the day, stress, anxiety, depression, etc.

• #38 Delayed Sleep Phase Syndrome: Symptoms, Causes, and More

  https://www.health.com/delayed-sleep-phase-syndrome-8575662

  Delayed sleep phase syndrome occurs when your body’s circadian rhythm is out of sync with your environment. Your circadian rhythm is a biological clock that lets your body know when to sleep and when to wake up. Environmental factors (like how light or dark it is outside) and certain hormones in your body (such as melatonin and cortisol) can also influence your circadian rhythm. […] Currently, researchers are unsure why people with DSPS experience changes in their sleep-wake cycle. However, some factors that can contribute to a misaligned internal clock include: […] Having a family history of DSPS […] Not getting enough sunlight during the day […] Living with mental health conditions like depression and obsessive-compulsive disorder (OCD) […] Undergoing physical and hormonal changes during and after puberty […] Experiencing low levels of melatonin, a hormone that helps your body induce sleep.

• #39 Delayed Sleep Phase Syndrome: Causes, Symptoms & Treatments

  https://www.healthline.com/health/sleep-deprivation/delayed-sleep-phase-syndrome

  Delayed sleep phase syndrome (DSPS) is a type of circadian rhythm sleep disorder. […] While the exact cause of DSPS isn’t known, it’s often associated with several factors. […] If you have a close relative with DSPS, you have a higher chance of developing the condition. Forty percent of people with DSPS have a family history of the disorder. […] During adolescence, the body’s 24-hour sleep cycle becomes longer, which requires later sleep and wake times. […] DSPS is linked to conditions like depression, anxiety, attention deficit hyperactivity disorder, and obsessive-compulsive disorder. […] DSPS affects 10 percent of people with chronic insomnia. […] DSPS symptoms can get worse if you don’t get enough light exposure in the morning. Symptoms might also increase if you’re exposed to too much light at night.

• #40 Delayed sleep phase syndrome: Effects, diagnosis, and more

  https://www.medicalnewstoday.com/articles/delayed-sleep-phase-syndrome-effects-diagnosis-and-more

  Delayed sleep phase syndrome (DSPS) is a chronic circadian rhythm disorder that causes a person to sleep late and wake up late. […] Melatonin imbalances may be a potential cause of DSPS. […] Some researchers associate adolescent DSPD with lower grades in school, alcohol use, smoking, and higher rates of depression and anxiety. […] In a person with a circadian rhythm disorder, such as DSPS, a persons sleep-wake cycle may be disturbed. This can cause difficulty sleeping and waking at appropriate times. […] People with ADHD are more likely to have DSPS than people without ADHD. […] According to older research, most people with DSPS typically have difficulty with the following: Falling asleep: Because their internal clock sends alerting signals until later than is typical, people cannot fall asleep for several hours after a typical bedtime. […] There is no permanent cure for DSPS. However, people can take steps to manage it using the treatment methods above. […] DSPS is a sleep disorder that delays a persons natural sleep-wake cycle. It is prevalent in adolescents, young adults, and people with ADHD.

• #41 What Is Delayed Sleep Phase Syndrome (DSPS)? – Stellar Sleep

  https://stellarsleep.com/learn/delayed-sleep-phase-syndrome/

  Delayed sleep phase syndrome is a kind of circadian rhythm sleep disorder. […] The exact cause of DSPS is still unknown but this disorder does tend to occur in a certain group of individuals more than others. […] Additionally, people with a strong background in DSPS are also more likely to acquire it which leads us to believe that it has a strong genetic disposition. […] Some environmental causes like lack of sunlight exposure and overexposure to bright lights during the evening are also likely to lead to DSPS. […] Furthermore, sudden psychiatric conditions have also been associated with the development of DSPS, these include depression, anxiety, attention deficit hyperactivity disorder, and obsessive-compulsive disorder.

• #42 Delayed Sleep Phase Disorder (Delayed Sleep Phase Syndrome) | The Better Sleep Clinic

  https://thebettersleepclinic.com/sleep-disorders/delayed-sleep-phase-disorder

  Certain personality characteristics may predispose individuals to DSWPD. A study by Micic et al. (2017) found that individuals with DSWPD reported higher neuroticism (emotional sensitivity) and significantly lower extraversion, conscientiousness, and agreeableness compared to healthy sleepers. These traits may influence behaviors around sleep routine, contributing to delayed sleep patterns. […] Puberty-related changes in the circadian system lead to a natural delay in sleep timing (Richardson et al., 2017). […] The homeostatic sleep drive accumulates more slowly in adolescents, potentially contributing to later bedtimes (Campbell et al., 2011). […] Social and academic pressures may encourage later sleep times, and poor sleep habits, reinforcing delayed patterns.

• #43 Sleep/Wake Cycle Disorders

  https://www.medscape.org/viewarticle/564378

  Circadian rhythm sleep disorders are a distinct class of sleep disorders. […] The most common primary circadian rhythm disorders are the circadian sleep phase disorders. […] The 2 primary factors that cause circadian-based sleep disorders are: Alterations to the external environment relative to the internal circadian timing system; Circadian sleep phase disorders related to alterations of the endogenous circadian system itself (these conditions are characterized by a shift in the timing of the major consolidated sleep period, with sleep being either delayed or advanced in relation to conventional sleep and wake times). […] Circadian Rhythm Sleep Disorder, Delayed Sleep Phase Syndrome (DSPS) is characterized by bedtimes and wake times that occur 3 to 6 hours later than the desired or conventional sleep/wake times.

• #44 Delayed Sleep Phase Disorder (Delayed Sleep Phase Syndrome) | The Better Sleep Clinic

  https://thebettersleepclinic.com/sleep-disorders/delayed-sleep-phase-disorder

  Certain personality characteristics may predispose individuals to DSWPD. A study by Micic et al. (2017) found that individuals with DSWPD reported higher neuroticism (emotional sensitivity) and significantly lower extraversion, conscientiousness, and agreeableness compared to healthy sleepers. These traits may influence behaviors around sleep routine, contributing to delayed sleep patterns. […] Puberty-related changes in the circadian system lead to a natural delay in sleep timing (Richardson et al., 2017). […] The homeostatic sleep drive accumulates more slowly in adolescents, potentially contributing to later bedtimes (Campbell et al., 2011). […] Social and academic pressures may encourage later sleep times, and poor sleep habits, reinforcing delayed patterns.

• #45 Sleep Problems in Teens – Sleep Medicine | UCLA Health

  https://www.uclahealth.org/medical-services/sleep-disorders/patient-resources/patient-education/sleep-and-teens

  Teens are so full of potential, so full of life, so…sleepy. Research shows that most teens do not get the sleep that they need on a daily basis. […] Causes for their lack of sleep include the following: Rapidly changing bodies, Busy schedules, Active social lives, A wrong view of sleep. […] The natural shift in a teen’s circadian rhythms is called „sleep phase delay.” The need to sleep is delayed for about two hours. […] This change in teenager sleep patterns is a normal part of growing up. […] Many barriers prevent teens from getting the sleep that they need. Their body clock begins to shift. […] A lack of sleep is not the only cause of daytime sleepiness. […] These disorders are common in teens. They can cause you to be sleepy during the school day and most alert at night. […] Huge swings in emotions and moods are also common in teens. This can result in major sleep issues. […] Medical conditions such as epilepsy or asthma can cause teens to have a hard time sleeping. Many medications will also affect how they sleep.

• #46 Delayed Sleep Phase Syndrome: Symptoms, Causes, and Treatment

  https://www.verywellmind.com/delayed-sleep-phase-syndrome-symptoms-causes-and-treatment-7110083

  Delayed sleep phase syndrome (DSPS) is a circadian rhythm sleep disorder that can cause your sleep-time and wake-time to be much later than most peoples. […] This condition occurs due to a delay in the timing of your internal body clock, or circadian rhythm, compared to traditional sleep and wake timings. […] These are some of the potential causes of delayed sleep phase syndrome: Hormonal imbalance: Hormones such as melatonin and cortisol help maintain your sleep-wake cycle by promoting sleepiness and wakefulness respectively. An imbalance in these hormones can lead to delayed sleep phase syndrome. […] Genetics: Delayed sleep phase syndrome may be hereditary, so you may be more likely to have it if someone in your immediate family has it. […] Puberty: Your circadian rhythm, also known as your internal body clock, changes when you reach puberty. While it’s normal for it to get slightly delayed, a significant delay, often due to fluctuations in your melatonin levels, can lead to delayed sleep phase syndrome.

• #47

  https://www.painscale.com/article/what-is-delayed-sleep-phase-syndrome

  Delayed sleep phase syndrome is most common among teenagers and young adults. Other biological factors increase the risk of DSPS, including the following: Assigned female at birth and between the ages of 40 and 60, Experienced symptoms in childhood (90% of adults with DSPS had symptoms as children), Family history of DSPS.

• #48 Circadian Rhythm Sleep Disorders – Brain, Spinal Cord, and Nerve Disorders – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/brain-spinal-cord-and-nerve-disorders/sleep-disorders/circadian-rhythm-sleep-disorders

  Causes of circadian rhythm sleep disorders may be internal or external. […] Internal causes include the following: Damage to the brainfor example, due to a brain infection (encephalitis), stroke, head injury, or Alzheimer disease. […] Insensitivity to the cycle of night and day. […] External causes include the following: Jet lag (especially when traveling from west to east). […] Working irregular shifts on a regular basis. […] Frequently going to bed and getting up at different times. […] Being confined to bed for a long time. […] Blindness or not being exposed to sunlight for long periods of time. […] Taking certain medications (or illicit drugs). […] Delayed sleep phase disorder occurs when people consistently go to sleep and awaken late (for example, go to sleep at 3 AM and wake up at 10 AM or as late as 1 PM). […] This syndrome is more common among adolescents and young adults than in adults. […] People with delayed sleep phase disorder cannot fall asleep earlier even if they try.

• #49 Delayed Sleep Phase Syndrome (DSPS): Causes, Symptoms, and Treatments  – Amerisleep

  https://amerisleep.com/blog/delayed-sleep-phase-syndrome/

  Delayed Sleep Phase Syndrome (DSPS): Causes, Symptoms, and Treatments […] It is caused by a delayed timing in the body’s internal sleep clock or circadian rhythm, often influenced by genetic factors. […] Recent research shows that there may be certain genetic factors that play a role in the pathogenesis of DSPS, including a common genetic mutation that impacts cryptochrome proteins. […] The mutation causes a small segment of the protein to be left out and this interference causes issues with sleep. […] Due to the genetic history link, doctors may ask for medical history and may look for links in family history to DSPS and other sleep disorders. […] According to the American Sleep Association, DSPS often develops in adolescence but continues through adulthood. […] Some even attribute DSPS to excessive jet lag due to long air travel time from the home destination and traveling between different time zones. […] A 2019 study also showed that this condition is more prevalent in young men and in middle aged women, but overall, there is no significant difference between genders.

• #50

  https://www.painscale.com/article/what-is-delayed-sleep-phase-syndrome

  Delayed sleep phase syndrome is most common among teenagers and young adults. Other biological factors increase the risk of DSPS, including the following: Assigned female at birth and between the ages of 40 and 60, Experienced symptoms in childhood (90% of adults with DSPS had symptoms as children), Family history of DSPS.

• #51 Delayed Sleep Phase Syndrome Symptoms And Causes

  https://welevelupfl.com/behavioral-health/delayed-sleep-phase-syndrome/

  Causes of Delayed Sleep Phase Disorder: Genetic predisposition: Family history of sleep disorders or altered circadian rhythms. Environmental factors: Exposure to light and darkness can impact the body’s internal clock. Developmental factors: Adolescents and young adults are more commonly affected, as circadian rhythms naturally shift later during these life stages. […] The exact causes of Delayed Sleep Phase Syndrome (DSPS), also known as Delayed Sleep-Wake Phase Disorder, are not fully understood. However, researchers believe that a combination of genetic, biological, and environmental factors contribute to the development of this sleep disorder. […] Genetic Predisposition: There is evidence to suggest that genetics plays a significant role in DSPS. Family history of sleep disorders or altered circadian rhythms can increase the likelihood of an individual developing DSPS.

• #52

  https://www.painscale.com/article/what-is-delayed-sleep-phase-syndrome

  Delayed sleep phase syndrome is most common among teenagers and young adults. Other biological factors increase the risk of DSPS, including the following: Assigned female at birth and between the ages of 40 and 60, Experienced symptoms in childhood (90% of adults with DSPS had symptoms as children), Family history of DSPS.

• #53 What Causes Sleep Disturbances in Kids? Disorders, Symptoms, Treatment

  https://www.emedicinehealth.com/what_causes_sleep_disturbances_in_kids/article_em.htm

  Causes of sleep disturbances (sleep disorders) in children include insomnia, delayed sleep phase syndrome (DSPS), hypersomnia (narcolepsy), parasomnias, movement disorders (restless legs syndrome, periodic limb movement disorder), obstructive sleep apnea (OSA), and behavioral and mental health disorders (autism spectrum disorder, attention deficit hyperactivity disorder [ADHD], anxiety and mood disorders). […] Delayed sleep phase syndrome (DSPS, also called sleepy teen syndrome) is an exaggerated form of the normal shift in circadian rhythm that occurs during late childhood or early adolescence (a type of circadian rhythm disorder). […] Causes of delayed sleep phase syndrome in kids include: being a natural night owl, genetics, early school start times, late evening activities, caffeine consumption, screen exposure late in the day, and lack of exposure to morning light.

• #54 Delayed Sleep Wake Phase Syndrome – Symptoms, Causes, and Treatment

  https://www.myupchar.com/en/disease/sleep-disorders/delayed-sleep-wake-phase-syndrome

  Delayed sleep-wake phase syndrome is a type of sleep disorder. […] This can be due to genetics, chronic insomnia, and poor sleeping habits. […] Although no specific causes of delayed sleep-wake phase syndrome are known, it is linked to genetics, chronic insomnia, and poor sleeping habits. […] If someone in the family already has delayed sleep-wake phase syndrome, then there is a possibility of developing this condition. […] According to research, 10 percent of people with chronic insomnia have a chance of having delayed sleep-wake phase syndrome. […] If there is depression, anxiety, obsessive-compulsive disorder, or attention deficit hyperactivity disorder, there is a possibility of delayed sleep-wake phase syndrome. […] During adolescence, the body’s sleep cycle becomes longer, which includes delayed sleep and delayed waking. […] Genetics, chronic insomnia, and poor sleeping habits are known to cause delayed sleep-wake phase syndrome.

• #55 Everything You Should Know About Delayed Sleep Phase Syndrome – CNET

  https://www.cnet.com/health/sleep/delayed-sleep-phase-syndrome/

  While the teenage years are when researchers see the greatest effects of delayed sleep, Figueiro explains that it is also associated with high risk for: Mental health issues, Sleep deprivation, Obesity, Other negative side effects. […] For people with delayed sleep, the main types of treatment that work best are cognitive behavior therapy, light therapy and melatonin. […] Currently, there isn’t one treatment solely for delayed sleepers, but there is hope that technology is one step closer to finding a solution. […] Two behavioral and physiological factors make being an early riser challenging for people with DSPS. Your circadian rhythm or internal clock has a lot to do with your biological makeup. […] If people with DSPS had a flexible schedule where they can work until 3 o’clock in the morning and then wake up at 11, then there’s no problem for them. The problem is the social structure we impose on them.

• #56 DSPD Q&A – Circadian Sleep Disorders Network

  https://www.circadiansleepdisorders.org/docs/DSPS-QandA.php

  People with DSPD who try to work normal work hours, such as 9 am to 5 pm, or students who have to attend morning classes, become sleep deprived. […] There are many long-term health effects of sleep deprivation. These can include depression, lowered immune response, anxiety disorders, weight gain, fibromyalgia, diabetes, and cancer. […] Many DSPD people need more sleep than normal sleepers. […] For those for whom treatment is ineffective, DSPD can make it impossible to maintain a 9 am to 5 pm work schedule. […] There is continuing research on the effects of light, dark, and melatonin on the circadian rhythm. More needs to be done to unravel the underlying causes of this disorder.

• #57 Delayed sleep phase syndrome: Effects, diagnosis, and more

  https://www.medicalnewstoday.com/articles/delayed-sleep-phase-syndrome-effects-diagnosis-and-more

  Delayed sleep phase syndrome (DSPS) is a chronic circadian rhythm disorder that causes a person to sleep late and wake up late. […] Melatonin imbalances may be a potential cause of DSPS. […] Some researchers associate adolescent DSPD with lower grades in school, alcohol use, smoking, and higher rates of depression and anxiety. […] In a person with a circadian rhythm disorder, such as DSPS, a persons sleep-wake cycle may be disturbed. This can cause difficulty sleeping and waking at appropriate times. […] People with ADHD are more likely to have DSPS than people without ADHD. […] According to older research, most people with DSPS typically have difficulty with the following: Falling asleep: Because their internal clock sends alerting signals until later than is typical, people cannot fall asleep for several hours after a typical bedtime. […] There is no permanent cure for DSPS. However, people can take steps to manage it using the treatment methods above. […] DSPS is a sleep disorder that delays a persons natural sleep-wake cycle. It is prevalent in adolescents, young adults, and people with ADHD.

• #58 Delayed sleep phase syndrome: Effects, diagnosis, and more

  https://www.medicalnewstoday.com/articles/delayed-sleep-phase-syndrome-effects-diagnosis-and-more

  Delayed sleep phase syndrome (DSPS) is a chronic circadian rhythm disorder that causes a person to sleep late and wake up late. […] Melatonin imbalances may be a potential cause of DSPS. […] Some researchers associate adolescent DSPD with lower grades in school, alcohol use, smoking, and higher rates of depression and anxiety. […] In a person with a circadian rhythm disorder, such as DSPS, a persons sleep-wake cycle may be disturbed. This can cause difficulty sleeping and waking at appropriate times. […] People with ADHD are more likely to have DSPS than people without ADHD. […] According to older research, most people with DSPS typically have difficulty with the following: Falling asleep: Because their internal clock sends alerting signals until later than is typical, people cannot fall asleep for several hours after a typical bedtime. […] There is no permanent cure for DSPS. However, people can take steps to manage it using the treatment methods above. […] DSPS is a sleep disorder that delays a persons natural sleep-wake cycle. It is prevalent in adolescents, young adults, and people with ADHD.

• #59 Everything You Should Know About Delayed Sleep Phase Syndrome – CNET

  https://www.cnet.com/health/sleep/delayed-sleep-phase-syndrome/

  DSPS is a circadian rhythm disorder that affects a person’s ability to go to bed at „normal” hours, which leads them to sleep most of the day away. […] There’s currently no single factor that explains why certain people get DSPS and why others don’t. Ultimately, some people’s internal clocks can’t conform to a socially acceptable circadian rhythm. […] What researchers have found is that many aspects of life can contribute to the offset. These factors can include: Genetics, Changes after puberty, Psychological and neurological disorders. […] Most studies show that having a circadian rhythm disorder starts during a person’s teenage years. Then, it gets progressively worse into young adulthood. […] DSPS is often misdiagnosed as insomnia, depression or other common sleep or mental health disorders.

• #60 Insomnia | Atrium Health Wake Forest Baptist

  https://www.wakehealth.edu/condition/i/insomnia

  Delayed sleep phase syndrome (DSPS) is believed to be a disorder of the body’s timing system the biological clock. […] DSPS is found in persons who get a normal or nearly normal amount of sleep, but the entire sleep cycle is shifted later than normal.

• #61 How to treat Delayed Sleep Phase Syndrome — Sleep Cycle

  https://www.sleepcycle.com/sleep-disorders/identifying-and-treating-delayed-sleep-phase-disorder/

  This syndrome describes a glitch in the bodys Circadian rhythm that causes the delay of a sleep pattern by two or more hours. […] Certain medical conditions, such as depression and anxiety, can increase the risk of developing DSPS. […] Genetics may also play a role in the development of DSPS. Research has found that certain genetic variations may be associated with an increased risk of developing DSPS. […] Melatonin supplements can be used to help regulate the sleep-wake cycle and shift the bodys natural sleep pattern. […] Delayed sleep phase syndrome and insomnia are two distinct conditions, and they cannot be used interchangeably. […] Individuals with DSPS do not intend to stay up late, but their internal clock delays their sleep, making it challenging to fall asleep and wake up at conventional times.

• #62 DSPD Q&A – Circadian Sleep Disorders Network

  https://www.circadiansleepdisorders.org/docs/DSPS-QandA.php

  Delayed Sleep Phase Disorder (DSPD), also known as Delayed Sleep Phase Syndrome (DSPS), is a neurological sleep disorder in which a person’s sleep/wake cycle is delayed with respect to the external day/night cycle. […] DSPD is a neurological disorder. However the stress of living with DSPD can lead to psychological problems including depression. […] Many people try to cope with DSPD by forcing themselves to keep a normal schedule. This results in a chronic sleep deficit, with symptoms that can mimic depression, attention deficit hyperactivity disorder, chronic fatigue syndrome, fibromyalgia, or just plain fatigue. […] DSPD people really are unable to fall asleep earlier. DSPD is not simply a „night owl” tendency, in which people prefer to stay up late and get up late, but are able to adjust to a daytime schedule when necessary.

• #63 Delayed sleep-wake phase disorder – Nesbitt – Journal of Thoracic Disease

  https://jtd.amegroups.org/article/view/18434/html

  Delayed sleep-wake phase disorder (DSWPD) is thought to be the most common of the circadian rhythm sleep-wake disorders (CRSDs); an increasingly recognized and diagnosed group of sleep disorders in which the main problem is inappropriate timing of the major sleep episode relative to the light-dark cycle. […] The control of timing of the major sleep episode is complex, and dependent largely on synchronised timing of two factors: circadian processes, and sleep homeostatic processes. […] In true DSWPD, both circadian and sleep timing are delayed relative to the solar cycle. However, a high proportion of people with the disorder will just have a delayed sleep episode, with normally aligned and entrained circadian timing. […] Numerous factors are likely to contribute to the pathophysiology of DSWPS, including behavioural and psychological, as well as biological factors.

• #64 Diagnosis, Cause, and Treatment Approaches for Delayed Sleep-Wake Phase Disorder – PubMed

  https://pubmed.ncbi.nlm.nih.gov/27542884/

  Delayed sleep-wake phase disorder (DSWPD) is commonly defined as an inability to fall asleep and wake at societal times resulting in excessive daytime sleepiness. […] Although the cause is multifaceted, delays in sleep time are largely driven by misalignment between the circadian pacemaker and the desired sleep-wake timing schedule. […] Current treatment approaches focus on correcting the circadian delay; however, there is a lack of data investigating combined therapies for treatment of DSWPD.

• #65 Delayed Sleep-Wake Phase – Sleep Education by the AASM

  https://sleepeducation.org/sleep-disorders/delayed-sleep-wake-phase/

  Delayed sleep-wake phase disorder (DSP) is a circadian rhythm disorder. It consists of a typical sleep pattern that is “delayed” by two or more hours from societal norms. This delay occurs when your internal sleep clock (circadian rhythm) is shifted later at night and later in the morning. […] A family history of DSP is common in about 40% of people with the disorder and there is likely a genetic component. Some environmental factors may also be involved. Both a lack of exposure to morning sunlight and too much exposure to bright light in the evening may increase symptoms of DSP. […] Strategically timed low dose melatonin use has been shown to be an effective treatment option in teens, and it may be somewhat effective in adults. Melatonin is a hormone that is widely available in supplement form. The hormone is naturally produced by your body and plays an important role in sleep. It helps regulate your sleep-wake cycle by signaling to your body when the time for sleep is approaching.

• #66 Delayed Sleep-Wake Phase – Sleep Education by the AASM

  https://sleepeducation.org/sleep-disorders/delayed-sleep-wake-phase/

  Delayed sleep-wake phase disorder (DSP) is a circadian rhythm disorder. It consists of a typical sleep pattern that is “delayed” by two or more hours from societal norms. This delay occurs when your internal sleep clock (circadian rhythm) is shifted later at night and later in the morning. […] A family history of DSP is common in about 40% of people with the disorder and there is likely a genetic component. Some environmental factors may also be involved. Both a lack of exposure to morning sunlight and too much exposure to bright light in the evening may increase symptoms of DSP. […] Strategically timed low dose melatonin use has been shown to be an effective treatment option in teens, and it may be somewhat effective in adults. Melatonin is a hormone that is widely available in supplement form. The hormone is naturally produced by your body and plays an important role in sleep. It helps regulate your sleep-wake cycle by signaling to your body when the time for sleep is approaching.

• #67 Delayed sleep phase disorder – Knowledge and References – Taylor & Francis

  https://taylorandfrancis.com/knowledge/Medicine_and_healthcare/Sleep_medicine/Delayed_sleep_phase_disorder/

  Delayed sleep phase disorder (DSPD) is a disorder of the timing of sleep; people suffering from DSPD typically go to bed late and wake up late (3–6 hours later than normal sleeping hours). […] The exact causes of DSPD are not actually known, but light exposure after minimum core body temperature and dim light during the evening have been shown to advance the phase of the master clock of persons with DSPD. […] If this delay becomes persistent and causes a functional impairment, the person has developed delayed sleep phase disorder (DSPD). DSPD is most common among adolescents and young adults, and the prevalence is about 1–10% in this group. […] This disorder often includes difficulties initiating sleep, fatigue, daytime sleepiness, concentration difficulties, irritability, depressive symptoms, and anxiety. […] Gradisar et al. (2011a) found that a combination of cognitive behavioral therapy and bright light treatment was effective in improving sleep in adolescents with delayed sleep phase disorder.

• #68 Everything You Should Know About Delayed Sleep Phase Syndrome – CNET

  https://www.cnet.com/health/sleep/delayed-sleep-phase-syndrome/

  While the teenage years are when researchers see the greatest effects of delayed sleep, Figueiro explains that it is also associated with high risk for: Mental health issues, Sleep deprivation, Obesity, Other negative side effects. […] For people with delayed sleep, the main types of treatment that work best are cognitive behavior therapy, light therapy and melatonin. […] Currently, there isn’t one treatment solely for delayed sleepers, but there is hope that technology is one step closer to finding a solution. […] Two behavioral and physiological factors make being an early riser challenging for people with DSPS. Your circadian rhythm or internal clock has a lot to do with your biological makeup. […] If people with DSPS had a flexible schedule where they can work until 3 o’clock in the morning and then wake up at 11, then there’s no problem for them. The problem is the social structure we impose on them.

• #69 Understanding Delayed Sleep Phase Syndrome (DSPS)

  https://sleephealthcare.com.au/understanding-delayed-sleep-phase-syndrome/?srsltid=AfmBOoqHhx0fij_CJyF47HJLEzmqnqNZbnkVSpiOg2i5CoTAQBPN55Fb

  What causes delayed sleep phase syndrome? […] Researchers believe that if you have DSPS, this clock will not work properly. They believe Melatonin is responsible for this. Your lifestyle may also play a role. […] DSPS patients sometimes think they have insomnia. This occurs because they are unable to fall asleep at the expected time. […] It might be worth asking your doctor for support in changing your sleep and wake times by taking Melatonin at night or by exposing yourself to light in the morning.

• #70

  https://link.springer.com/article/10.1007/s41105-023-00454-4

  Delayed sleepwake phase disorder (DSWPD) is a circadian rhythm sleep disorder characterised by a delay in the main sleep period, with patients experiencing difficulty getting to sleep and waking up at socially appropriate times. […] However, no treatment to date addresses the tendency to phase delay, which is a common factor amongst the various contributing causes of DSWPD. […] There is also increasing evidence that, on top of problems with the circadian cycle, sleep homeostatic processes actually differ in DSWPD patients compared to controls. […] This naturally has ramifications for management but also for the current approach to the pathogenesis itself in which DSWPD is considered a purely circadian disorder. […] This review collates what is known on the causes and treatments of DSWPD, addresses the pitfalls in diagnosis and discusses the implications of current data on modified sleep homeostasis, making clinical recommendations and directing future research.

• #71 Diagnosis, Cause, and Treatment Approaches for Delayed Sleep-Wake Phase Disorder – PubMed

  https://pubmed.ncbi.nlm.nih.gov/27542884/

  Delayed sleep-wake phase disorder (DSWPD) is commonly defined as an inability to fall asleep and wake at societal times resulting in excessive daytime sleepiness. […] Although the cause is multifaceted, delays in sleep time are largely driven by misalignment between the circadian pacemaker and the desired sleep-wake timing schedule. […] Current treatment approaches focus on correcting the circadian delay; however, there is a lack of data investigating combined therapies for treatment of DSWPD.

• #72 Scientists discover how a common mutation leads to 'night owl’ sleep disorder | ScienceDaily

  https://www.sciencedaily.com/releases/2020/10/201027105354.htm

  The mutation affects a protein called cryptochrome, one of four main clock proteins. […] The cryptochrome mutation causes a small segment on the „tail” of the protein to get left out, and Partch’s lab found that this changes how tightly cryptochrome binds to the CLOCK:BMAL1 complex. […] Without it, cryptochrome binds more tightly and stretches out the length of the clock each day. […] Partch’s lab is currently doing just that, conducting screening assays to identify molecules that bind to the pocket in the clock’s molecular complex. „We know now that we need to target that pocket to develop therapeutics that could shorten the clock for people with delayed sleep phase disorder,” she said.

• #73 Common Genetic Mutation Can Lead to Delayed Sleep Phase Disorder

  https://www.pharmacytimes.com/view/common-genetic-mutation-can-lead-to-delayed-sleep-phase-disorder

  Genetic mutation affects cryptochrome proteins, which are 1 of 4 main clock proteins involved in regulating the biological clock. […] Investigators have found that a relatively common genetic mutation throws off the timing of the biological clock, resulting in a common sleep syndrome called delayed sleep phase disorder. […] Research in 2017 discovered a surprisingly common mutation that causes this disorder by altering a key component of the biological clock. […] Daily cycles in virtually every aspect of our physiology are driven by cyclical interactions of clock proteins in cells, although genetic variations that change the clock proteins can alter the timing of the clock and cause sleep phase disorders. […] This mutation has dramatic effects on peoples sleep patterns, so its exciting to identify a concrete mechanism in the biological clock that links the biochemistry of this protein to the control of human sleep behavior, said corresponding author Carrie Partch, PhD, in a press release. […] Partch added that ongoing research on treatments should target that pocket in order to shorten the clock for people with delayed sleep phase disorder.

• #74 The etiology of delayed sleep phase disorder – PubMed

  https://pubmed.ncbi.nlm.nih.gov/26434674/

  According to classification manuals for sleep disorders, nine disorders are directly related to biological clock timing misalignments. Of all, delayed sleep phase disorder (DSPD) is the most commonly diagnosed, predominantly affecting adolescents, young adults, and insomnia patients. […] Considerable evidence shows a delay in the circadian clock to be associated with DSPD. […] However, follow up studies show frequent patient relapse, leading researchers to speculate that alternative etiologies may be contributing to sleep and circadian clock delays in DSPD. […] The aim of the present paper is to review and collate current literature related to DSPD etiology in order to outline gaps in current knowledge and suggest future research.

• #75 DSPD Q&A – Circadian Sleep Disorders Network

  https://www.circadiansleepdisorders.org/docs/DSPS-QandA.php

  People with DSPD who try to work normal work hours, such as 9 am to 5 pm, or students who have to attend morning classes, become sleep deprived. […] There are many long-term health effects of sleep deprivation. These can include depression, lowered immune response, anxiety disorders, weight gain, fibromyalgia, diabetes, and cancer. […] Many DSPD people need more sleep than normal sleepers. […] For those for whom treatment is ineffective, DSPD can make it impossible to maintain a 9 am to 5 pm work schedule. […] There is continuing research on the effects of light, dark, and melatonin on the circadian rhythm. More needs to be done to unravel the underlying causes of this disorder.

• #76 How a Genetic Mutation Causes Delayed Sleep Phase Disorder | Sleep Review

  https://sleepreviewmag.com/sleep-disorders/circadian-rhythm-disorders/delayed-phase/genetic-mutation-causes-delayed-phase-disorder/

  The mutation affects a protein called cryptochrome, one of four main clock proteins. […] The cryptochrome mutation causes a small segment on the tail of the protein to get left out, and Partch’s lab found that this changes how tightly cryptochrome binds to the CLOCK:BMAL1 complex. […] How tightly the complex partners bind to this pocket determines how quickly the clock runs, Partch says. […] We know now that we need to target that pocket to develop therapeutics that could shorten the clock for people with delayed sleep phase disorder, she says.

• #77

  https://link.springer.com/article/10.1007/s41105-023-00454-4

  Delayed sleepwake phase disorder (DSWPD) is a circadian rhythm sleep disorder characterised by a delay in the main sleep period, with patients experiencing difficulty getting to sleep and waking up at socially appropriate times. […] However, no treatment to date addresses the tendency to phase delay, which is a common factor amongst the various contributing causes of DSWPD. […] There is also increasing evidence that, on top of problems with the circadian cycle, sleep homeostatic processes actually differ in DSWPD patients compared to controls. […] This naturally has ramifications for management but also for the current approach to the pathogenesis itself in which DSWPD is considered a purely circadian disorder. […] This review collates what is known on the causes and treatments of DSWPD, addresses the pitfalls in diagnosis and discusses the implications of current data on modified sleep homeostasis, making clinical recommendations and directing future research.

• #78 DSPD Q&A – Circadian Sleep Disorders Network

  https://www.circadiansleepdisorders.org/docs/DSPS-QandA.php

  People with DSPD who try to work normal work hours, such as 9 am to 5 pm, or students who have to attend morning classes, become sleep deprived. […] There are many long-term health effects of sleep deprivation. These can include depression, lowered immune response, anxiety disorders, weight gain, fibromyalgia, diabetes, and cancer. […] Many DSPD people need more sleep than normal sleepers. […] For those for whom treatment is ineffective, DSPD can make it impossible to maintain a 9 am to 5 pm work schedule. […] There is continuing research on the effects of light, dark, and melatonin on the circadian rhythm. More needs to be done to unravel the underlying causes of this disorder.

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