Infekcja helicobacter pylori
Objawy

Infekcja Helicobacter pylori dotyczy około 50% populacji światowej, z czego 80% nosicieli pozostaje bezobjawowych. U około 20% zakażonych rozwijają się objawy kliniczne, najczęściej związane z przewlekłym zapaleniem błony śluzowej żołądka lub chorobą wrzodową, manifestujące się tępych lub palącym bólem w nadbrzuszu, nasilającym się 2-3 godziny po posiłku lub na czczo, często ustępującym po jedzeniu lub lekach zobojętniających kwas. Infekcja przebiega etapowo: ostra faza z objawami zapalenia żołądka i podwyższonym pH soku żołądkowego (do pH 7,0) ustępuje po około 2 tygodniach, po czym następuje faza przewlekła z powrotem do kwaśnego pH (około 2) i naciekiem zapalnym. H. pylori jest główną przyczyną choroby wrzodowej żołądka i dwunastnicy (odpowiada za 90-100% wrzodów dwunastnicy i 60-100% wrzodów żołądka), a także powikłań takich jak krwawienia, perforacje i blokady żołądka. U dzieci i osób starszych objawy mogą być mniej specyficzne, a infekcja może manifestować się także pozapokarmowymi skutkami, jak niedokrwistość z niedoboru żelaza, immunologiczna plamica małopłytkowa czy przewlekła pokrzywka.

Objawy infekcji Helicobacter pylori

Infekcja Helicobacter pylori (H. pylori) jest jedną z najczęstszych infekcji bakteryjnych u ludzi, występującą u około połowy światowej populacji. Charakterystyczną cechą tej infekcji jest fakt, że większość osób zakażonych bakterią H. pylori nie doświadcza żadnych objawów – szacuje się, że aż 80% nosicieli bakterii nie ma świadomości zakażenia.123

Bezobjawowy przebieg infekcji

Chociaż większość zakażonych nie rozwija żadnych objawów, H. pylori może powodować przewlekłe zapalenie błony śluzowej żołądka (gastritis), bez powodowania dolegliwości. Pacjenci mogą przez lata, a nawet dziesięciolecia, pozostawać nosicielami bakterii bez świadomości zakażenia.45 Infekcja często nabywa się w dzieciństwie, jednak objawy, jeśli w ogóle się pojawią, zazwyczaj rozwijają się dopiero w wieku dorosłym.6

Typowe objawy kliniczne

U około 20% zakażonych osób infekcja H. pylori może prowadzić do objawów klinicznych, które najczęściej są związane z rozwojem zapalenia błony śluzowej żołądka lub wrzodów trawiennych. Do najczęstszych objawów należą:178

  • Tępy lub palący ból w górnej części brzucha (nadbrzuszu)
  • Ból pojawiający się 2-3 godziny po posiłku lub na czczo (szczególnie w nocy)
  • Dolegliwości bólowe, które mogą ustępować po posiłku, spożyciu mleka lub przyjęciu leków zobojętniających kwas żołądkowy
  • Wzdęcia i uczucie pełności
  • Nudności i wymioty
  • Częste odbijanie
  • Utrata apetytu
  • Niezamierzona utrata masy ciała

91011

Objawy te mogą pojawiać się i ustępować cyklicznie przez okres od kilku dni do nawet kilku tygodni. Intensywność objawów jest zróżnicowana – u niektórych pacjentów mogą być one łagodne i niespecyficzne, podczas gdy u innych mogą znacząco wpływać na jakość życia.1213

Rozwój infekcji i jej progresja

Infekcja H. pylori rozwija się stopniowo i może przechodzić przez różne stadia, przy czym progresja jest zwykle powolna i może zatrzymać się na dowolnym etapie. Proces od zakażenia do rozwoju poważnych powikłań trwa zazwyczaj dekady.14

Ostre zakażenie

W pierwszym tygodniu po zakażeniu H. pylori mogą wystąpić objawy ostrego zapalenia żołądka i jelit, takie jak nudności, wymioty, ból w nadbrzuszu i zgaga. Objawy te osiągają maksymalne nasilenie około 9-12 dnia od zakażenia, a następnie zaczynają ustępować. Większość objawów zanika po około 2 tygodniach od zakażenia.15

Badanie endoskopowe może wykazać zaczerwienienie błony śluzowej żołądka (rumień) około piątego dnia infekcji, a pH soku żołądkowego może wzrosnąć do wartości neutralnej (pH 7,0). Zmiany endoskopowe poprawiają się po 2 tygodniach, choć pH pozostaje podwyższone.15

Przewlekłe zakażenie

Po około 2 miesiącach od zakażenia, jeśli infekcja nie zostanie wyleczona, przechodzi w fazę przewlekłą. Obraz endoskopowy wraca do normy, ale zwiększa się naciek limfocytów i komórek plazmatycznych, a pH soku żołądkowego ponownie spada do wartości kwaśnych (pH 2).15

Przewlekła infekcja H. pylori może prowadzić do różnych stanów chorobowych, z których najczęstsze to:1617

  • Przewlekłe zapalenie błony śluzowej żołądka (gastritis) – stan zapalny wyścielający żołądek, który może nie powodować objawów lub wywoływać dolegliwości dyspeptyczne
  • Choroba wrzodowa żołądka i dwunastnicy – H. pylori jest przyczyną około 90-100% wrzodów dwunastnicy i 60-100% wrzodów żołądka
  • Zanikowe zapalenie błony śluzowej żołądka – zanik komórek żołądka i upośledzenie funkcji trawiennych
  • Metaplazja jelitowa – transformacja wyściółki żołądka

1418

Objawy zaawansowanych powikłań

W przypadku progresji choroby i rozwoju poważnych powikłań, takich jak wrzody trawienny, mogą wystąpić bardziej nasilone objawy:1920

  • Krwawienie z przewodu pokarmowego – objawia się krwawymi wymiotami lub wymiotami o wyglądzie fusów kawowych
  • Smoliste, czarne stolce (melena) – świadczące o krwawieniu z górnego odcinka przewodu pokarmowego
  • Objawy niedokrwistości z niedoboru żelaza (zmęczenie, bladość, duszność przy wysiłku) – spowodowane przewlekłym, powolnym krwawieniem
  • Perforacja (przedziurawienie) ściany żołądka – objawia się nagłym, ostrym bólem brzucha
  • Blokada opróżniania żołądka – spowodowana bliznowaceniem po wrzodach

2116

Ciężkie objawy, które pojawiają się nagle, mogą wskazywać na niedrożność jelit, perforację lub krwawienie – wszystkie te stany są sytuacjami nagłymi, wymagającymi natychmiastowej pomocy medycznej.1622

Rozwój choroby wrzodowej w przebiegu infekcji H. pylori

H. pylori jest najczęstszą przyczyną choroby wrzodowej żołądka i dwunastnicy. Szacuje się, że około 10-15% osób zakażonych H. pylori rozwinie chorobę wrzodową.916

Mechanizm powstawania wrzodów

Bakteria H. pylori przyczynia się do powstawania wrzodów poprzez kilka mechanizmów:1223

  • Uszkodzenie ochronnej warstwy śluzu wyścielającej żołądek i dwunastnicę
  • Zwiększenie produkcji kwasu żołądkowego
  • Wytwarzanie toksyn uszkadzających komórki nabłonka
  • Zakłócanie naturalnych mechanizmów obronnych żołądka przed kwasem żołądkowym
  • Wywoływanie przewlekłego stanu zapalnego

19

Objawy choroby wrzodowej

Objawy wrzodów wywołanych przez H. pylori mogą obejmować:32425

  • Ból w nadbrzuszu – opisywany jako gniotący, palący lub gryzący, występujący pomiędzy mostkiem a pępkiem
  • Ból pojawiający się najczęściej na czczo, między posiłkami lub w nocy
  • Ból trwający od kilku minut do kilku godzin
  • Dolegliwości ustępujące po posiłku lub przyjęciu leków zobojętniających kwas żołądkowy
  • Uczucie pełności po zjedzeniu niewielkiej ilości pokarmu
  • Nudności i wymioty
  • Utrata apetytu
  • Niewyjaśniona utrata masy ciała

2627

Małe wrzody mogą nie powodować żadnych objawów, podczas gdy większe mogą prowadzić do poważnych krwawień. Ból związany z wrzodami może być różny u różnych pacjentów, a niektórzy nie odczuwają żadnego bólu.9

Objawy szczególne u różnych grup pacjentów

Objawy u dzieci

Większość dzieci zakażonych H. pylori nie wykazuje żadnych objawów.1 Jeśli objawy występują, są one podobne do objawów u dorosłych, ale mogą być trudniejsze do zidentyfikowania ze względu na ograniczoną zdolność dzieci do opisywania swoich dolegliwości.628

  • Ból brzucha
  • Mdłości
  • Wymioty
  • Uczucie pełności
  • Utrata apetytu
  • Niechęć do jedzenia

2930

U dzieci z przewlekłą infekcją H. pylori mogą również wystąpić objawy pozajelitowe, takie jak niedokrwistość z niedoboru żelaza i przewlekła immunologiczna małopłytkowość (cITP).2931

Objawy u osób starszych

U osób starszych infekcja H. pylori może przebiegać z mniej typowymi objawami, a dodatkowo mogą występować:3213

  • Słabiej wyrażone dolegliwości bólowe
  • Przewlekłe zmęczenie
  • Postępująca utrata masy ciała
  • Niedokrwistość bez wyraźnej przyczyny
  • Większe ryzyko poważnych powikłań krwotocznych

33

Pozażołądkowe objawy infekcji H. pylori

Poza typowymi objawami ze strony przewodu pokarmowego, infekcja H. pylori może być związana z różnymi objawami pozażołądkowymi:33

  • Niedokrwistość z niedoboru żelaza (IDA) – związana z powolnym, trudnym do wykrycia krwawieniem z przewodu pokarmowego spowodowanym zapaleniem żołądka wywołanym przez H. pylori
  • Immunologiczna plamica małopłytkowa (ITP) – rzadkie zaburzenie autoimmunologiczne, w którym układ odpornościowy niszczy płytki krwi
  • Przewlekła pokrzywka samoistna (CSU) – nawracająca wysypka skórna z bąblami i świądem
  • Niedobór witaminy B12 – może prowadzić do niedokrwistości megaloblastycznej, neuropatii i zmian poznawczych

3334

Eradykacja H. pylori wiąże się z poprawą w przypadku niedokrwistości z niedoboru żelaza, immunologicznej plamicy małopłytkowej i przewlekłej pokrzywki samoistnej.33

Związek infekcji H. pylori z nowotworem żołądka

Długotrwała infekcja H. pylori jest znaczącym czynnikiem ryzyka rozwoju raka żołądka. Bakteria H. pylori została sklasyfikowana jako karcynogen klasy I przez Międzynarodową Agencję Badań nad Rakiem.435

Mechanizm karcynogenezy

Przewlekłe zapalenie błony śluzowej żołądka wywołane przez H. pylori uważane jest za pierwszy krok w rozwoju raka żołądka. Proces ten obejmuje kilka etapów:144

  • Przewlekłe zapalenie błony śluzowej żołądka
  • Zanikowe zapalenie błony śluzowej żołądka
  • Metaplazja jelitowa
  • Dysplazja
  • Rak żołądka (gruczolakorak)

1418

Szacuje się, że H. pylori odpowiada za około 89% wszystkich przypadków raka żołądka i jest związane z rozwojem 5,5% wszystkich przypadków nowotworów na świecie.4

Objawy sugerujące rozwój nowotworu

Rak żołądka we wczesnych stadiach często nie daje objawów lub powoduje niespecyficzne dolegliwości. Objawy, które mogą sugerować rozwój nowotworu żołądka w przebiegu przewlekłej infekcji H. pylori, obejmują:83632

  • Uporczywe bóle brzucha
  • Uczucie pełności po zjedzeniu nawet niewielkich porcji pokarmu
  • Postępująca, niewyjaśniona utrata masy ciała
  • Przewlekły brak apetytu
  • Nudności i wymioty
  • Trudności w połykaniu
  • Przewlekłe zmęczenie
  • Wzdęcia i dyskomfort w brzuchu

3738

H. pylori jest również związane z chłoniakiem typu MALT (mucosa-associated lymphoid tissue) żołądka. Prawie wszystkie przypadki chłoniaka MALT żołądka są związane z infekcją H. pylori, choć ryzyko rozwoju tego nowotworu u osób zakażonych jest niskie (mniej niż 1%).3518

Objawy alarmowe wymagające natychmiastowej konsultacji medycznej

Niektóre objawy w przebiegu infekcji H. pylori wymagają natychmiastowej pomocy medycznej, gdyż mogą świadczyć o poważnych powikłaniach:23920

  • Krwawe wymioty lub wymioty o wyglądzie fusów kawowych
  • Smoliste, czarne lub krwawe stolce
  • Ostry, silny ból brzucha, który nie ustępuje lub promieniuje do pleców
  • Nagła bladość, zawroty głowy lub omdlenia (mogą świadczyć o masywnym krwawieniu)
  • Trudności w oddychaniu
  • Niewyjaśniona, nagła utrata masy ciała
  • Trudności w połykaniu
  • Wymioty uniemożliwiające przyjmowanie płynów

404142

Powyższe objawy mogą wskazywać na krwawiący wrzód, perforację ściany żołądka lub dwunastnicy, niedrożność przewodu pokarmowego lub inne poważne powikłania, które są stanami zagrażającymi życiu.2243

Czynniki wpływające na nasilenie objawów

Nasilenie objawów infekcji H. pylori może być różne u różnych pacjentów i zależy od wielu czynników:744

  • Wirulencja szczepu bakterii – niektóre szczepy H. pylori wytwarzają więcej cytotoksyn i czynników wirulencji
  • Odpowiedź immunologiczna gospodarza – indywidualna reakcja układu odpornościowego na zakażenie
  • Czas trwania infekcji – im dłużej trwa zakażenie, tym większe ryzyko rozwoju powikłań
  • Inne czynniki drażniące błonę śluzową żołądka – takie jak palenie tytoniu, alkohol, leki przeciwzapalne (NLPZ), kofeiną
  • Predyspozycje genetyczne – niektóre osoby mogą być genetycznie bardziej podatne na uszkodzenia wywołane przez H. pylori
  • Dieta – niektóre produkty spożywcze mogą nasilać objawy (ostre przyprawy, napoje gazowane, kwaśne pokarmy)
  • Stres – może nasilać objawy poprzez zwiększenie produkcji kwasu żołądkowego

4546

Podsumowanie objawów w przebiegu infekcji H. pylori

Infekcja Helicobacter pylori charakteryzuje się szerokim spektrum objawów – od całkowitego braku dolegliwości u większości zakażonych, przez niespecyficzne objawy dyspeptyczne, aż po poważne powikłania związane z chorobą wrzodową i nowotworem żołądka.31

Najczęstsze objawy infekcji H. pylori to:7910

  • Tępy lub palący ból w nadbrzuszu
  • Uczucie pełności i wzdęcia
  • Nudności i wymioty
  • Odbijanie i zgaga
  • Utrata apetytu
  • Niewyjaśniona utrata masy ciała

4748

W przypadku rozwoju choroby wrzodowej dochodzi charakterystyczny ból, który:242549

  • Często występuje między posiłkami lub na czczo
  • Może budzić w nocy
  • Zwykle ustępuje po posiłku lub lekach zobojętniających
  • Ma charakter nawracający, trwający od kilku minut do godzin
  • Może promieniować do pleców

50

Należy pamiętać, że obecność H. pylori zwiększa ryzyko rozwoju raka żołądka, dlatego ważne jest wczesne rozpoznanie i leczenie infekcji, szczególnie u pacjentów z objawami sugerującymi powikłania.13551

Kolejne rozdziały

Zapraszamy do dalszego czytania naszego leksykonu.

Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.

  1. 12.04.2026
  2. www.leksykon.com.pl

Materiały źródłowe

  • #1 H. Pylori Infection: How Do You Get, Causes, Symptoms, Tests & Treatment
    https://my.clevelandclinic.org/health/diseases/21463-h-pylori-infection
    H. pylori is a bacteria that can cause peptic ulcer disease and gastritis. Only 20% of those infected have symptoms. Symptoms include dull or burning stomach pain, unplanned weight loss and bloody vomit. H. pylori can also inflame and irritate the stomach lining (gastritis). Untreated, long-term H. pylori infection can lead to stomach cancer (rarely). […] Most children with H. pylori infection don’t have symptoms. Only about 20% do. […] Symptoms and signs, if present, are those that arise from gastritis or peptic ulcer and include: Dull or burning pain in your stomach (more often a few hours after eating and at night). Your pain may last minutes to hours and may come and go over several days to weeks. Unplanned weight loss. Bloating. Nausea and vomiting (bloody vomit). Indigestion (dyspepsia). Burping. Loss of appetite. Dark stools (from blood in your stool). […] If you have an H. pylori infection, you have an increased risk for stomach cancer later in life.
  • #2 H. Pylori: Signs and symptoms | Zuckerman College of Public Health
    https://publichealth.arizona.edu/outreach/health-literacy-awareness/hpylori/signs-symptoms
    The majority of people with H. pylori infection have no signs or symptoms. Most of the symptoms are related to stomach inflammation and ulcers, including: Upper abdominal pain and discomfort […] In some cases, patients may feel hungry in the morning. Often the symptoms occur after eating, and many times patients waken in the early morning hours with abdominal pain. H. pylori has also been associated with iron-deficiency anemia due to chronic internal bleeding. […] Vomiting blood or passing black, tarry, or bloody stools are medical emergencies and should not be ignored if you have these symptoms, you should seek immediate medical attention.
  • #3 Patient education: Helicobacter pylori infection and treatment (Beyond the Basics) – UpToDate
    https://www.uptodate.com/contents/helicobacter-pylori-infection-and-treatment-beyond-the-basics/print
    Helicobacter pylori, also known as H. pylori, is a bacterium that is commonly found in the stomach. It is present in approximately one-half of the world’s population. […] The vast majority of people infected with H. pylori has no symptoms and will never develop problems. However, H. pylori is capable of causing a number of digestive problems, including ulcers and, much less commonly, stomach cancer. […] Most individuals with chronic gastritis or duodenitis caused by H. pylori have no symptoms. However, approximately 5 to 10 percent of people develop more serious problems, including stomach or duodenal ulcers and, rarely, tumors of the stomach. […] Ulcers can cause a variety of symptoms or no symptoms at all, with the most common ulcer symptoms including: Pain or discomfort (usually in the upper abdomen), Bloating, Feeling full after eating a small amount of food, Lack of appetite, Nausea or vomiting, Dark or tar-colored stools, Ulcers that bleed can cause a low blood count and fatigue.
  • #4 Helicobacter pylori – Wikipedia
    https://en.wikipedia.org/wiki/Helicobacter_pylori
    Infection of the stomach with H. pylori does not necessarily cause illness: over half of the global population is infected, but most individuals are asymptomatic. Persistent colonization with more virulent strains can induce a number of gastric and non-gastric disorders. Gastric disorders due to infection begin with gastritis, or inflammation of the stomach lining. When infection is persistent, the prolonged inflammation will become chronic gastritis. Initially, this will be non-atrophic gastritis, but the damage caused to the stomach lining can bring about the development of atrophic gastritis and ulcers within the stomach itself or the duodenum (the nearest part of the intestine). At this stage, the risk of developing gastric cancer is high. However, the development of a duodenal ulcer confers a comparatively lower risk of cancer. Helicobacter pylori are class 1 carcinogenic bacteria, and potential cancers include gastric MALT lymphoma and gastric cancer. Infection with H. pylori is responsible for an estimated 89% of all gastric cancers and is linked to the development of 5.5% of all cases cancers worldwide. H. pylori is the only bacterium known to cause cancer.
  • #5 HELICOBACTER PYLORI – a patient’s guide – Family Doctor
    https://www.familydoctor.co.nz/categories/bowel-and-abdominal-problems/helicobacter-pylori-a-patients-guide/
    Helicobacter pylori is a bacteria which infects the stomach, causing stomach upsets and peptic ulcers. This article discusses the infection and how it can be eradicated. […] Most people have no symptoms. […] H.Pylori causes inflammation in the lining of the stomach (called the „mucosa”) and one consequence of this may be Gastritis, with symptoms of dyspepsia (pain or discomfort in the upper abdomen), nausea and bloating. […] Symptoms of an uncomplicated ulcer are very similar to those of gastritis, with dyspepsia, nausea and bloating. […] Gastric cancer is associated with infection with H.Pylori, although the lifetime risk is very low. […] Everyone with dyspepsia (pain or discomfort in the upper abdomen ongoing for some time) who tests positive for H.Pylori should be offered eradication. […] If the symptoms of dyspepsia disappear after completing the course of treatment, it is not necessary to repeat the urea breath test, which may be used to confirm eradication.
  • #6 Helicobacter pylori Infections (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/h-pylori.html
    Helicobacter pylori (H. pylori) are a type of bacteria. These germs are a common cause of digestive illnesses, including: gastritis: the irritation and inflammation of the stomach lining, peptic ulcers (often called stomach ulcers): sores in the lining of the stomach, small intestine, or esophagus, later in life, stomach cancer. […] Many people who get an H. pylori infection dont realize it. Often, these infections dont cause symptoms. […] When the bacteria do cause symptoms, they’re usually either symptoms of gastritis or peptic ulcer disease. […] In kids, symptoms of gastritis (ga-STRYE-tis) may include: nausea, vomiting, belly pain, bloating. […] In older kids and adults, the most common symptom of peptic ulcers is a lasting or burning belly pain, usually in the area below the ribs and above the navel. This pain often gets worse on an empty stomach and gets better as soon as the person eats food, drinks milk, or takes antacid medicine.
  • #7 H. pylori Infection: Symptoms, Causes, and Treatment
    https://www.webmd.com/digestive-disorders/h-pylori-helicobacter-pylori
    Helicobacter pylori (H. pylori) is a type of bacteria that infects your stomach. It can cause sores and inflammation in the lining of your stomach or the upper part of your small intestine (the duodenum). For some people, an infection can lead to stomach cancer. […] Infection with H. pylori is common. About two-thirds of the worlds population has it in their bodies. For most people, it never causes any symptoms. But it’s the most common cause of peptic ulcers, which are painful open sores in your digestive tract. In rare cases, it could even lead to stomach cancer. […] Just having the bacteria doesn’t cause symptoms. But you’ll probably notice them if you get stomach inflammation (gastritis) or a peptic ulcer due to H pylori. The most common issue is a dull or burning pain in your belly. The feeling may come and go, and may worsen when your stomach is empty. You may feel better after you eat, drink milk, or take an antacid. Other symptoms include: Bloating, Burping, No appetite, Nausea, Vomiting, Weight loss for no clear reason.
  • #8 H. Pylori Infection: Symptoms, Causes, and More
    https://www.healthline.com/health/helicobacter-pylori
    H. pylori is a bacteria that can damage the stomachs protective lining. Untreated, an H.pylori infection may lead to complications. H. pylori often infects a persons stomach during childhood. Infections are typically harmless and dont cause symptoms. However, in some cases, they may lead to stomach ulcers and some diseases. […] Most people with H. pylori never have symptoms. However, its estimated that 30% of people with H. pylori develop other conditions, such as gastritis and peptic ulcers. This is because the bacteria could damage the inner protective lining of your stomach. Symptoms of a peptic ulcer from H. pylori may include: dull or burning stomach pain, feeling full quickly after starting to eat, bloating, nausea, unexplained weight loss, vomiting, burping. […] Although rare, H. pylori infections may increase your risk of developing stomach cancer. This is due to chronic inflammation caused by the infection. Some symptoms of stomach cancer may include: heartburn, acid reflux, indigestion, difficulty swallowing, poor appetite, unexplained weight loss, discomfort or swelling in the abdomen, fatigue.
  • #9 Helicobacter pylori infection
    https://www.ucsfhealth.org/medical-tests/helicobacter-pylori-infection
    H pylori infection is the most common cause of peptic ulcers. […] About 10% to 15% of people infected with H pylori develop peptic ulcer disease. Small ulcers may not cause any symptoms. Some ulcers can cause serious bleeding. […] An aching or burning pain in your abdomen is a common symptom. The pain may be worse with an empty stomach. The pain can differ from person to person, and some people have no pain. […] Other symptoms include: Feeling of fullness or bloating and problems drinking as much fluid as usual, Hunger and an empty feeling in the stomach, often 1 to 3 hours after a meal, Mild nausea that may go away with vomiting, Loss of appetite, Weight loss without trying, Burping, Bloody or dark, tarry stools or bloody vomit. […] A chronic infection with H pylori may lead to: Peptic ulcer disease, Chronic inflammation, Gastric and upper intestine ulcers, Stomach cancer, Gastric mucosa-associated lymphoid tissue (MALT) lymphoma. […] Severe symptoms that begin suddenly may indicate a blockage in the intestine, perforation, or hemorrhage, all of which are emergencies. Symptoms may include: Tarry, black, or bloody stools, Severe vomiting, which may include blood or a substance with the appearance of coffee
  • #10 Helicobacter Pylori: Symptoms, Causes, and Treatment
    https://patient.info/digestive-health/dyspepsia-indigestion/helicobacter-pylori
    Helicobacter pylori is a type of bacteria. It’s commonly found in the stomach. Many people with Helicobacter pylori have no symptoms at all, but it can cause stomach irritation (gastritis) and stomach ulcers. […] Most people with H. pylori have no symptoms at all. H. pylori can cause stomach irritation (gastritis), stomach and duodenal (small bowel) ulcers. It can – rarely – cause stomach cancer. […] Common symptoms of H. pylori gastritis or ulcers include pain in the top part of the abdomen (stomach), below the rib cage and in the middle. This can feel like an ache, a discomfort, a burning pain, or sometimes a sharp pain. The pain is often affected by eating; it may get worse after eating, although sometimes it improves after eating. Nausea (feeling sick), and frequent burping are also symptoms.
  • #11 How to spot H. pylori – an infection that can cause gastritis and ulcers | Digestive | UT Southwestern Medical Center
    https://utswmed.org/medblog/h-pylori-gut-bacteria-gastritis/
    Helicobacter pylori, or H. pylori, are common bacteria that infect billions of people worldwide. They are the leading cause of ulcers and gastritis (inflammation of the stomach lining). But approximately 80% of infected people worldwide will never develop symptoms a phenomenon that researchers are still learning about. […] Over time, urea breaks down the stomach lining, causing gastritis and ulcers painful, nonhealing wounds in the stomach lining. If left untreated, chronic gastritis can increase the risk of stomach cancer. […] While approximately 5 billion people worldwide have H. pylori bacteria in their stomach, only about 20% of infected people have noticeable symptoms such as: Aching or burning stomach pain, Bloating, Frequent burping, Loss of appetite, Nausea, Unintentional weight loss.
  • #12 Helicobacter pylori Infection – Digestive Disorders – Merck Manual Consumer Version
    https://www.merckmanuals.com/home/digestive-disorders/gastritis-and-peptic-ulcer-disease/helicobacter-pylori-infection
    Helicobacter pylori (H. pylori) infection is a bacterial infection that causes stomach inflammation (gastritis), peptic ulcer disease, and certain types of stomach cancer. […] When symptoms of H. pylori infection do occur, they include indigestion and pain or discomfort in the upper abdomen. […] Many people whose gastritis is caused by H. pylori infection do not have symptoms or complications such as a peptic ulcer of the stomach or duodenum. […] People who do develop symptoms resulting from H. pylori infection have those that are typical of gastritis, including indigestion and pain or discomfort in the upper abdomen. […] Ulcers caused by H. pylori infection cause symptoms similar to ulcers caused by other disorders, including pain in the upper abdomen. […] Virtually all people who have H. pylori infection have stomach inflammation (gastritis), which may affect the entire stomach or only the lower part (antrum). Infection can sometimes lead to erosive gastritis and perhaps even a stomach (gastric) ulcer or duodenal ulcer. […] H. pylori contributes to ulcer formation by increasing acid production, interfering with the stomach’s normal defenses against stomach acid, and producing toxins. […] Long-term infection with H. pylori increases the risk of stomach cancer.
  • #13 Helicobacter pylori (H. pylori) Infection Symptoms & Treatment
    https://www.medicinenet.com/helicobacter_pylori/article.htm
    Most individuals with Helicobacter pylori infections have few or no symptoms. Some may experience a few symptoms from mild gastritis episodes, for example: Minor belching, Bloating, Nausea, Vomiting, Abdominal discomfort. […] However, those individuals who have more serious infection experience signs and symptoms of stomach and duodenal ulcers or severe gastritis which include: Abdominal pain and/or discomfort that usually does not wax and wane, Nausea and vomiting sometimes with blood that is red, or the color is like coffee grounds or like vomitus, Dark or tar-like stools (black color of feces due to bleeding ulcers), Fatigue, Low red blood cell counts due to bleeding, The full feeling after consuming a small amount of food, A decreased appetite that is more constant. […] Persons with symptoms of black, tarry stools, and fatigue should seek immediate medical help or go to an emergency department to be evaluated for intestinal bleeding.
  • #14 H. Pylori: Transmission and Spread of Infection | Zuckerman College of Public Health
    https://publichealth.arizona.edu/outreach/health-literacy-awareness/hpylori/transmission-spread
    H. pylori enters the body through the mouth, moves through the digestive system, and infects the stomach or the first part of the small intestine. The spiral-shaped bacterium uses its tail-like flagella to move around and burrow into the stomach lining, which causes inflammation. […] Depending on where the infection occurs in the stomach, H. pylori can also cause overproduction of stomach acid. […] While there is no formal progression of the H. pylori infection, several steps are well documented. This process is very slow, taking decades, and may stop at any step because gastric cancers probably require several other factors to develop in addition H. pylori infection. […] Stage 2: Inflammation of the stomach lining (chronic gastritis) […] Stage 3: Loss of stomach cells and impaired digestive system (atrophic gastritis) […] Stage 4: Transformation of the stomach lining (intestinal metaplasia) […] Stage 5: Beginning stages of stomach cancer (dysplasia) […] Stage 6: Stomach cancer (gastric adenocarcinoma)
  • #15 Symptoms of Acute and Chronic H. pylori Infection | SpringerLink
    https://link.springer.com/chapter/10.1007/978-981-287-706-2_15
    Helicobacter pylori (H. pylori) has urease and ureI gene to overcome gastric acid to survive on the acidic human stomach mucous membrane. Once H. pylori enters the stomach, acute gastroenteritis symptoms, such as nausea, vomiting, epigastric pain, and heartburn, occur. These symptoms emerge within the first week of infection, and the symptoms reach their maximum severity on the ninth to 12th day of the infection. Then, the symptoms get better, and most of those are gone after 2 weeks of the infection. Based on a gastroscopic view of H. pylori infection, erythema can be seen on the gastric mucosa after the fifth day of infection, and gastric juice pH is reported to be 7.0, which is neutral. Then, the erythema findings get better after 2 weeks of infection, while the gastric juice pH is 7.5, which is indifferent. Later, the gastroscopic view is back to normal after 74 days of H. pylori infection, while lymphocyte and plasma cell infiltrations increase, and gastric juice pH becomes 2. Thus, continued H. pylori infection after 2 months can be considered as chronic infection. Once chronic infection is maintained, H. pylori influences on symptoms that might be related to the brain-gut axis through various immunologic mechanisms and is expected to cause symptoms on organs other than stomach. However, unequivocal data concerning the direct and immediate effect of H. pylori infection on the brain-gut axis are still lacking. Therefore, further studies evaluating the clinical importance of these host-bacteria interactions will improve our understanding of H. pylori infection pathophysiology.
  • #16 Helicobacter pylori infection Information | Mount Sinai – New York
    https://www.mountsinai.org/health-library/diseases-conditions/helicobacter-pylori-infection
    A chronic infection with H pylori may lead to: Peptic ulcer disease, Chronic inflammation, Gastric and upper intestine ulcers, Stomach cancer, Gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Other complications may include: Severe blood loss, Scarring from an ulcer may make it harder for the stomach to empty, Perforation or hole of the stomach and intestines, Iron deficiency anemia. […] Severe symptoms that begin suddenly may indicate a blockage in the intestine, perforation, or hemorrhage, all of which are emergencies. Symptoms may include: Tarry, black, or bloody
  • #16 Helicobacter pylori infection Information | Mount Sinai – New York
    https://www.mountsinai.org/health-library/diseases-conditions/helicobacter-pylori-infection
    Helicobacter pylori (H pylori) is a type of bacteria that infects the stomach. It is very common, affecting about two thirds of the world’s population. H pylori infection is the most common cause of peptic ulcers. However, the infection does not cause problems for most people. […] About 10% to 15% of people infected with H pylori develop peptic ulcer disease. Small ulcers may not cause any symptoms. Some ulcers can cause serious bleeding. An aching or burning pain in your abdomen is a common symptom. The pain may be worse with an empty stomach. The pain can differ from person to person, and some people have no pain. Other symptoms include: Feeling of fullness or bloating and problems drinking as much fluid as usual, Hunger and an empty feeling in the stomach, often 1 to 3 hours after a meal, Mild nausea that may go away with vomiting, Loss of appetite, Weight loss without trying, Burping, Bloody or dark, tarry stools or bloody vomit.
  • #17 Helicobacter pylori infection: MedlinePlus Medical EncyclopediaLock
    https://medlineplus.gov/ency/article/007715.htm
    A chronic infection with H pylori may lead to: Peptic ulcer disease, Chronic inflammation, Gastric and upper intestine ulcers, Stomach cancer, Gastric mucosa-associated lymphoid tissue (MALT) lymphoma. Other complications may include: Severe blood loss, Scarring from an ulcer may make it harder for the stomach to empty, Perforation or hole of the stomach and intestines, Iron deficiency anemia.
  • #18 Helicobacter pylori: Infectious substances pathogen safety data sheet – Canada.ca
    https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/helicobacter-pylori.html
    Atrophic gastritis and intestinal metaplasia are precursors to gastric cancer and are strongly associated with H. pylori infection in adults. Gastric cancer types include adenocarcinomas, which account for 95% of gastric cancers, and gastric lymphomas, such as mucosal-associated lymphoid tissue (MALT) lymphoma. Gastric adenocarcinoma can be classified according to anatomic site of occurrence. Cardia adenocarcinomas are located near oesophagus, whereas non-cardia adenocarcinomas occur in the mid and distal region of the stomach. Nearly 90% of non-cardia adenocarcinomas and 72-98% of gastric MALT lymphomas are associated with H. pylori. The 5-year survival rate for gastric cancer in the United States has been reported to be between 31% and 36%, but is variable depending on the cancer stage at the time of intervention.
  • #19 Helicobacter Pylori: Symptoms, Causes, and Treatment
    https://patient.info/digestive-health/dyspepsia-indigestion/helicobacter-pylori
    Other symptoms, which can suggest a more serious problem, like a bleeding ulcer or stomach cancer, include unintentional weight loss, vomiting blood, having black, sticky, 'tar-like’ poo (melaena), and symptoms of anaemia, like feeling short of breath, looking pale, or feeling very tired. […] H. pylori infection is very common. Globally, around half of all people have it. It is more common in developing countries. […] In the UK, roughly 3 to 4 out of every 10 people have H. pylori. H. pylori infection seems to be becoming less common over time. Once someone gets H. pylori, unless treated, it usually stays for the rest of their life. […] Gastritis means inflammation of the lining of the stomach. This can cause symptoms such as upper abdominal (tummy) pain and nausea. […] H. pylori is the most common cause of stomach and duodenal ulcers. It causes ulcers in the same way that it causes gastritis, by triggering inflammation and damage of the lining of the stomach or duodenum. The protective barrier that prevents acid damage to the stomach seems to be affected, too. It can also cause the stomach to produce more acid, which causes damage to the duodenum.
  • #20 Helicobacter pylori Infections (for Parents) | Nemours KidsHealth
    https://kidshealth.org/en/parents/h-pylori.html
    Peptic ulcers that bleed can cause: hematemesis (hee-muh-TEM-uh-sis): bloody vomit or vomit that looks like coffee grounds, melena (muh-LEE-nuh): stool (poop) that’s black, bloody, or looks like tar. […] A single antibiotic may not kill the bacteria, so doctors often prescribe a combination of antibiotics. […] Antibiotic treatment cures many cases of gastritis and peptic ulcer disease caused by H. pylori, especially ulcers in the duodenum. […] Call your doctor right away if your child has any of these symptoms: severe belly pain, vomit that’s bloody or looks like coffee grounds, poop that’s bloody, black, or looks like tar, lasting gnawing or burning pain in the area below the ribs that gets better after eating, drinking milk, or taking antacids.
  • #21 6 Signs You May Have H Pylori: Digestive Disease Specialists: Gastroenterology Practice
    https://www.ddsqc.com/blog/6-signs-you-may-have-h-pylori
    Left untreated, H. pylori infections can lead to internal bleeding, stomach perforation, or peritonitis, which is a serious and potentially life-threatening infection of the lining of the abdominal cavity. […] Plus, some of these symptoms can be associated with other serious medical problems, including stomach cancer. Early evaluation can help you get the appropriate treatment before complications have a chance to develop.
  • #22 Helicobacter pylori – Symptoms, Causes, Treatments
    https://resources.healthgrades.com/right-care/infections-and-contagious-diseases/helicobacter-pylori
    H pylori causes irritation, inflammation and damage to the stomach lining that may result in a number of symptoms. The symptoms can vary in intensity among individuals. […] You may experience H pylori bacteria symptoms daily or just once in a while. At times, any of these abdominal symptoms can be severe: Burning stomach pain, Frequent belching, Nausea with or without vomiting, Poor appetite, Stomach bloating, Unintentional weight loss. […] In some cases, H pylori bacteria can be life threatening. Seek immediate medical care (call 911) if you, or someone you are with, have any of these life-threatening symptoms including: Bloody stool (blood may be red, black, or tarry in texture), Severe or persistent abdominal pain, Vomiting blood or black material (resembling coffee grounds). […] Left untreated, H. pylori bacteria can result in bleeding ulcers, a serious and even life-threatening complication.
  • #23 H.Pylori Infection (Stomach Ulcer) – Alpha Digestive & Liver Centre
    https://alphagastro.sg/conditions/hpylori-infection/
    Helicobacter pylori (H. pylori) infection is a bacterial infection that causes ulcers of the stomach and duodenum, certain types of stomach cancer and inflammation of the stomach (gastritis) and duodenum (duodenitis). Infection is very common and is the most common cause of gastritis, duodenitis and peptic ulcer disease. […] Some people with H. pylori develop symptoms such as: Pain or discomfort in the upper abdomen, Indigestion, Loss of appetite, Nausea, Bloating, Frequent burping. […] Youre advised to consult a doctor should you experience any of the symptoms above. […] H. pylori infection can irritate your stomach or duodenum, causing inflammation. […] H. pylori can damage the protective lining of your stomach, allowing stomach acid to create an open sore (ulcer) in the stomach or duodenum.
  • #24 Helicobacter Pylori
    https://dph.illinois.gov/topics-services/diseases-and-conditions/diseases-a-z-list/helicobacter-pylori.html
    Most persons who are infected with H. pylori never have any symptoms or problems related to this infection; however, H. pylori can cause gastritis (inflammation of the lining of the stomach) or ulcers of the stomach or duodenum. About 25 million Americans suffer from ulcers. […] The most common ulcer symptom is gnawing or burning pain in the abdomen between the breastbone and the navel. Commonly, the pain occurs when the stomach is empty between meals and in the early morning hours but it also can occur at other times of the day. It may last from minutes to hours and may be relieved by eating or taking antacids. Less common symptoms include nausea, vomiting and loss of appetite. Sometimes ulcers may bleed; if bleeding continues for a long time, it may lead to anemia with weakness and fatigue. If bleeding is heavy, blood may appear in vomit or stool. Stool containing blood may appear tarry or black.
  • #25
    https://www.healthychildren.org/English/health-issues/conditions/abdominal/Pages/Helicobacter-Pylori-Infections.aspx
    Helicobacter pylori (H. pylori) is a bacterium that can cause an infection in your child’s stomach. H. pylori infection can cause inflammation in the lining of the stomach, known as gastritis, and peptic ulcers (sores) in the stomach and duodenum (the first section of the small intestine). […] When H. pylori causes an ulcer, the intensity of the symptoms can vary. In some cases, there will be no symptoms at all. […] Ulcers can cause a burning or gnawing pain in upper area of abdomen that may come and go. The pain can be aggravated by meals if the ulcer is in the stomach. Or, it can be relieved by meals if the ulcer is in the duodenum. Pain can occur during the night. […] Other H. pylori symptoms may include: Bloating, Burping, Nausea and vomiting, Loss of appetite, Weight loss, Bloody vomit and dark stools from bleeding in the stomach or duodenum, Anemia with no clear cause that does not respond to treatment to iron supplements.
  • #26 H. Pylori | Helicobacter Pylori Infections | MedlinePlus
    https://medlineplus.gov/helicobacterpyloriinfections.html
    Helicobacter pylori (H. pylori) is a type of bacteria that causes infection in the stomach. It is the main cause of peptic ulcers, and it can also cause gastritis and stomach cancer. […] H. pylori usually does not cause symptoms. But it can break down the inner protective coating in some people’s stomachs and cause inflammation. This can lead to gastritis or a peptic ulcer. […] A peptic ulcer causes a dull or burning pain in your stomach, especially when you have an empty stomach. It lasts for minutes to hours, and it may come and go for several days or weeks. It may also cause other symptoms, such as bloating, nausea, and weight loss. […] If you have the symptoms of a peptic ulcer, your health care provider will check to see whether you have H. pylori. There are blood, breath, and stool tests to check for H. pylori. In some cases, you may need an upper endoscopy, often with a biopsy. […] If you do have a peptic ulcer, the treatment is with a combination of antibiotics and acid-reducing medicines. You will need to be tested again after treatment to make sure the infection is gone.
  • #27 Patient education: Helicobacter pylori infection and treatment (Beyond the Basics) – UpToDate
    https://www.uptodate.com/contents/helicobacter-pylori-infection-and-treatment-beyond-the-basics
    Helicobacter pylori, also known as H. pylori, is a bacterium that causes a chronic infection of the stomach. Most people infected with H. pylori have no problems. However, some people develop problems such as chronic gastritis, stomach ulcers and, rarely, stomach tumors. […] Most individuals with chronic gastritis or duodenitis caused by H. pylori have no symptoms. However, approximately 5 to 10 percent of people develop more serious problems, including stomach or duodenal ulcers and, rarely, tumors of the stomach. […] Ulcers may cause no symptoms, or may cause pain or discomfort (usually in the upper abdomen), bloating, feeling full after eating a small amount of food, lack of appetite, nausea, vomiting, and dark or tar-colored stools. Ulcers that bleed can cause a low blood count. […] H. pylori testing is recommended for anyone with a peptic (stomach or duodenal) ulcer or chronic stomach pain or nausea. […] Anyone diagnosed with H. pylori should be treated. H. pylori treatment helps to heal the ulcer, lowers the risk that the ulcer will return, and lowers the risk of bleeding from the ulcer.
  • #28 Pediatric H. pylori infection – Children’s Health
    https://www.childrens.com/specialties-services/conditions/helicobacter-pylori-h-pylori-infection
    H. pylori often causes no symptoms or problems. However, in some children it can cause stomach ulcers or inflammation in the stomach or small intestine. […] What are the signs and symptoms of pediatric H. pylori infection? Anemia (low blood counts). Blood in the stool. Excessive burping. Feeling of being bloated. Fever. Gnawing pain in the stomach that may come and go, or a severe, ongoing pain. Heartburn. Nausea. Never being hungry. Trouble swallowing. Unexplained, sudden weight loss. Many children infected with H. pylori have no symptoms. If your child shows any of these symptoms, contact your child’s pediatrician. They can be a sign of H. Pylori or other gastrointestinal problems. […] H. Pylori infection is treated with medicines. Your child will take: A combination of antibiotics to kill the bacteria. A stomach-acid reducing medication (called a proton-pump inhibitor) that allow ulcers to heal. Your child may also be asked to take an anti-diarrhea medicine that coats the inside of the stomach to protect it from acid while it heals. Your doctor may test your child after 4 weeks of treatment to make sure the infection is gone and their stomach has healed.
  • #29 Helicobacter Pylori – StatPearls – NCBI Bookshelf
    https://www.ncbi.nlm.nih.gov/books/NBK534233/
    H. pylori is a gram-negative, microaerophilic bacterium that can infect humans. It is often found in the stomach of affected individuals and causes inflammation and ulceration. Patients harboring the bacteria are asymptomatic with abdominal pain, nausea, vomiting, and dyspepsia developing only after gastritis and peptic ulcer disease have set in. […] The majority of children with H. pylori infection are asymptomatic. Symptoms, if present, are usually of gastritis or peptic ulcer disease such as abdominal pain, nausea, vomiting or dyspepsia. Children with these gastrointestinal symptoms should be investigated to identify the underlying etiology of the symptoms. […] There are various extra-intestinal manifestations that are associated with H. pylori infection such as iron deficiency anemia and chronic immune thrombocytopenia (cITP). Therefore, guidelines recommend that non-invasive testing for H. pylori can be considered in children with cITP or with refractory iron deficiency anemia without an identifiable cause. Children may also be anemic as it has been documented that those infected with H. pylori have lower iron stores.
  • #30 Pediatric H. Pylori Infections – Conditions and Treatments | Children’s National Hospital
    https://www.childrensnational.org/get-care/health-library/h-pylori-infections
    H. pylori is a spiral-shaped germ (bacteria) that infects the stomach. […] It can damage the tissue in your child’s stomach and the first part of the small intestine (duodenum). This can cause redness and swelling (inflammation). It may also cause painful sores called peptic ulcers in the upper digestive tract. […] Most people have the H. pylori bacteria for years without knowing it because they don’t have any symptoms. […] After being infected with H. pylori, your child may have an inflammation of the stomach lining. This is called gastritis. But most people never have symptoms or problems from the infection. […] When symptoms do occur, they may include belly pain, which can: Be a dull, gnawing pain, Happen 2 to 3 hours after a meal or immediately after, Come and go for a few days or weeks, Occur in the middle of the night when your child’s stomach is empty, Be eased by eating or taking an antacid medicine.
  • #31 Helicobacter pylori (H. pylori) – Digestive Topics
    https://gikids.org/digestive-topics/helicobacter-pylori/
    Some children with chronic H. pylori infection also have iron deficiency anemia. […] H. pylori infection is treated with a combination of antibiotics to kill the bacteria, acid-blocking medications, and stomach lining protectors (bismuth medicines such as Pepto-Bismol) to help heal the ulcers and reduce irritation in the stomach and duodenum. […] Even after treatment, it can take weeks to months for your child’s symptoms to fully disappear.
  • #32 H. Pylori (helicobacter pylori) infection: Symptoms and more
    https://www.medicalnewstoday.com/articles/311636
    Helicobacter pylori (H. pylori) is a type of bacteria that affects the stomach and small bowel. It is often symptomless, but it can increase the risk of ulcers, gastritis, and cancer, all of which can cause pain and other symptoms. […] Many people with H. pylori do not have any signs or symptoms. However, if people get an illness caused by H. pylori, they may have various symptoms. […] Symptoms of a stomach ulcer might include a sharp pain in the upper belly area that radiates to the back. The pain can get better or worse with eating, which may also be associated with abdominal fullness or bloating. There may be temporary relief from taking an antacid. However, the pain does come back. […] Symptoms of dyspepsia often include upper belly pain, nausea, and vomiting. […] Possible symptoms of stomach cancer include belly pain or swelling, loss of appetite, nausea or indigestion, feeling full without eating very much, vomiting, and weight loss.
  • #33 What Are the Extragastric Manifestations of H pylori Infection? – Gastroenterology Advisor
    https://www.gastroenterologyadvisor.com/features/what-are-the-extragastric-manifestations-of-h-pylori-infection/
    Helicobacter pylori (H pylori) infection is estimated to affect more than 50% of the global population, with an established causative role in peptic ulcer disease, gastric carcinoma, and other GI disorders. […] Studies have also shown that eradication of H pylori can lead to resolution or improvement in some of these extragastric manifestations along with related GI complications. […] H pylori infection has been associated with multiple extragastric complications, including iron deficiency anemia (IDA), immune thrombocytopenic purpura (ITP), and chronic spontaneous urticaria (CSU). […] Unexplained IDA associated with H pylori is thought to be due to slow, hard-to-detect blood loss from H pylori-induced gastric inflammation. […] B12 deficiency associated with H pylori leads to extragastric clinical signs and symptoms, such as megaloblastic anemia, neuropathy, and cognitive changes, and may accelerate cardiovascular diseases among others. […] H pylori eradication is associated with improvement in IDA, ITP, and CSU. […] Treatment of H pylori has been reported to reverse the anemia and ITP.
  • #34 H. pylori, Helicobacter pylori infection and skin diseases
    https://dermnetnz.org/topics/helicobacter-pylori-infection-and-skin-diseases
    H. pylori infection is more common in developing nations. […] Most individuals with H. pylori infection have no symptoms. Symptoms arise if infection with H. pylori causes peptic ulcers or gastritis. These symptoms can be non-specific and may include: Abdominal pain (usually in the upper abdomen), Nausea, Vomiting, Bloating, Red or tar-coloured stools (indicating bleeding in the intestine), Low blood count (anaemia). […] The damage to the lining of the stomach is due to a complex interaction of the bacteria and the host’s immune response. […] Treatment of H. pylori infection involves taking several medications for 7 to 14 days (’triple therapy’), for example, a proton-pump inhibitor (inhibitor of stomach acid secretion) such as omeprazole 40mg once daily, amoxicillin 1g twice daily and clarithromycin 500mg twice daily. Treatment cures up to 90% of individuals. […] Several small studies have suggested that eradicating H. pylori has a positive outcome on certain skin diseases such as urticaria, Behet disease, lichen planus, atopic dermatitis, Sweet syndrome, and systemic sclerosis. Conditions which may not benefit are psoriasis and rosacea.
  • #35 Helicobacter pylori | Canadian Cancer Society
    https://cancer.ca/en/cancer-information/reduce-your-risk/get-vaccinated/helicobacter-pylori
    H. pylori infection is a major cause of stomach (gastric) cancer. H. pylori causes long-lasting gastritis, which is thought to be the first step in developing stomach cancer. […] H. pylori infection is related to a higher risk of MALT lymphoma of the stomach. This is a type of non-Hodgkin lymphoma. Nearly all MALT lymphomas of the stomach are related to H. pylori infection. People infected with H. pylori have a low risk of developing MALT lymphoma (less than 1%). […] People infected with H. pylori are usually given a combination of antibiotics and a drug to help reduce acid in the stomach for 7 to 14 days. It cures H. pylori infection in 80% to 90% of people.
  • #36 H. pylori Infection: Symptoms, Causes, and Treatment
    https://www.webmd.com/digestive-disorders/h-pylori-helicobacter-pylori
    An H. pylori infection is also a risk factor for stomach cancer, which has few symptoms at first. Call your doctor if you have any of these signs: Belly pain or swelling, Bloating, Nausea, Loss of appetite, Feeling full after you eat just a small amount, Vomiting, Weight loss for no reason, Black poop. […] H. pylori commonly causes inflammation to the lining of your stomach (gastritis). You don’t always have symptoms from gastritis, but the irritation and swelling it causes can lead to discomfort, nausea, and vomiting. Peptic ulcers are the most common complication of H. pylori. About 10% of those infected with the bacteria will get one. A serious one could: Block digested food from leaving your stomach, Leave a hole in the wall of your stomach, Cause bleeding. […] Its not common, but an untreated long-term H. pylori infection is a risk factor for some types of stomach cancer. The disease has few symptoms at first, such as heartburn. Over time, you may notice: Belly pain or swelling, Nausea, Not feeling hungry, Feeling full after you eat just a small amount, Vomiting, Weight loss for no reason.
  • #37 H. Pylori Infection: Signs and Symptoms
    https://www.health.com/h-pylori-symptoms-7509557
    H. pylori infections are common in childhood, but typically dont cause any symptoms. When symptoms do occur, they are the same for kids as for adults: stomach pain, bloating, burping, nausea and vomiting, and loss of appetite. […] If you have any symptoms of a peptic ulcer, like bloating, nausea and vomiting, burning abdominal pain, or loss of appetite, see a healthcare provider; they can test you for the presence of the H. pylori bacteria and, if positive, treat the infection with antibiotics and other medications. […] More rarely, a prolonged H. pylori infection can increase your risk for certain types of stomach cancers and esophageal cancer. The types of stomach cancers associated with H. pylori are rare, but the bacteria appears to be the leading cause of these cancers. If you have any symptoms of stomach or esophageal cancer such as poor appetite, persistent belly pain, vomiting, bloody stool, chronic cough, hoarseness, or difficulty swallowing make an appointment with a healthcare provider as soon as possible.
  • #38 Symptoms of Helicobacter pylori Infection – AL BORG DIAGNOSTICS
    https://alborgdx.com/ksa/en/symptoms_of_helicobacter_pylori_infection/
    While stomach cancer is rare, the risk of developing it increases in individuals infected with H.pylori. The main symptoms of stomach cancer include: Poor appetite. Feeling full after eating only a small amount of food. Unexplained weight loss. Stomach pain. Fatigue and weakness. Abdominal swelling. Blood in the stool. […] H.pylori-induced ulcers can cause severe bleeding in the stomach and intestines in addition to the symptoms above. This is considered a life-threatening condition.
  • #39 H. Pylori Infection
    https://www.nhsgp.net/h-pylori-infection/
    If youre worried about your digestion and think you might have a stomach infection causing you problems, you should speak to your GP about the situation. You should speak to a healthcare professional and ask for an emergency appointment if you: Feel sick for more than 48 hours, Experience unexpected weight loss, Feel a sharp pain in your tummy, especially if that pain gets worse over time, The pain returns after taking antacids, Have an ulcer and your stomach feels hard to the touch, Experience unexplained weight loss. […] You should call 999 or go to AE immediately if you: Vomiting blood. This blood may appear bright red or have a dark brown, grainy appearance, like coffee grounds, Have poo that is bloody or dark, sticky and tar-like, and is extremely smelly.
  • #40
    https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=uh3180
    Your test shows the presence of Helicobacter pylori (H. pylori), a kind of bacterium that lives in the lining of the stomach. But sometimes H. pylori causes an upset stomach or a sore (ulcer) in the stomach lining. Most stomach ulcers are caused by H. pylori. Symptoms of an ulcer include gnawing or burning pain in the belly that can last minutes or hours. Eating food or taking antacids helps relieve the pain, but the symptoms may come back after a while. […] Call your doctor or nurse advice line now or seek immediate medical care if: You have new or worse belly pain. You are vomiting. Your stools are black and look like tar, or they have streaks of blood. […] Watch closely for changes in your health, and be sure to contact your doctor or nurse advice line if: You do not get better as expected.
  • #41 H. Pylori Infection | CommonSpirit Health
    https://www.commonspirit.org/conditions-treatments/h-pylori-infection
    Most people don’t have any symptoms. But sometimes an H. pylori infection causes an upset stomach or a stomach sore (ulcer). Symptoms of an ulcer include gnawing or burning pain in the belly that can last for hours. Taking antacids or eating helps relieve the pain, but the symptoms may come back. […] An infection with the bacteria Helicobacter pylori (H. pylori) can cause gastritis. H. pylori is also the bacteria that causes ulcers. […] You have new or worse belly pain. […] You are vomiting. […] Your stools are black and look like tar, or they have streaks of blood.
  • #42 Riyadh Fakeeh Care
    https://en.dsfhriyadh.fakeeh.care/blog/h-pylori-symptoms-causes-and-treatment
    H. pylori can cause symptoms and even further health complications if left untreated, such as: […] While many people with H. Pylori are asymptomatic, some may experience the following: […] Stomach Pain (the most common symptom) Dull or burning pain in the stomach, often worsens when the stomach is empty, such as between meals or at night, and may improve after eating, drinking milk, or taking an antacid. […] Nausea and vomiting. […] Loss of appetite. […] Burping often. […] Bloating. […] Indigestion. […] Unexplained weight loss. […] See a doctor if the symptoms described above persist or worsen to receive proper diagnosis and treatment. […] Seek medical care immediately if you experience any of these symptoms: Severe and persistent abdominal pain that wakes you up at night. […] Bloody or black, tarry-colored stool. […] Throwing up blood, which may be coffee-colored or bright red because blood is present in the vomit. […] Difficulty breathing. […] Dizziness or fainting. […] Pale skin.
  • #43 H Pylori (Helicobacter Pylori) Infection – What You Need to Know
    https://www.drugs.com/cg/h-pylori-helicobacter-pylori-infection.html
    You have bloody bowel movements, bloody vomit, or vomit that looks like coffee grounds. You have sudden, sharp stomach pain that does not go away or spreads to your back. […] Your symptoms do not improve with treatment. You feel full after eating only a small amount of food. You lose weight without trying. You have questions or concerns about your condition or care.
  • #44 Helicobacter pylori – Wikipedia
    https://en.wikipedia.org/wiki/Helicobacter_pylori
    Most people infected with H. pylori never experience any symptoms or complications, but will have a 10% to 20% risk of developing peptic ulcers or a 0.5% to 2% risk of stomach cancer. H. pylori induced gastritis may present as acute gastritis with stomach ache, nausea, and ongoing dyspepsia (indigestion) that is sometimes accompanied by depression and anxiety. Where the gastritis develops into chronic gastritis, or an ulcer, the symptoms are the same and can include indigestion, stomach or abdominal pains, nausea, bloating, belching, feeling hunger in the morning, feeling full too soon, and sometimes vomiting, heartburn, bad breath, and weight loss. […] Complications of an ulcer can cause severe signs and symptoms such as black or tarry stool indicative of bleeding into the stomach or duodenum; blood – either red or coffee-ground colored in vomit; persistent sharp or severe abdominal pain; dizziness, and a fast heartbeat. Bleeding is the most common complication. In cases caused by H. pylori there was a greater need for hemostasis often requiring gastric resection. Prolonged bleeding may cause anemia leading to weakness and fatigue. Inflammation of the pyloric antrum, which connects the stomach to the duodenum, is more likely to lead to duodenal ulcers, while inflammation of the corpus may lead to a gastric ulcer.
  • #45 H. pylori Infection: ACG Updates Treatment Recommendations | AAFP
    https://www.aafp.org/pubs/afp/issues/2018/0115/p135.html
    Determinants of success can be related to patient factors or to the infection. […] Of the infection-related factors, antibiotic sensitivity was found to be the most important determinant of treatment success in clinical trials and population-based studies. […] Because of the declining success rate of H. pylori eradication therapy, persistent infection is not uncommon after treatment. […] If infection persists after treatment, the same antibiotics should be avoided when retreating the patient.
  • #46 H. Pylori Infection: Symptoms, causes, treatments, and your questions answered.
    https://examine.com/conditions/h-pylori-infection/?srsltid=AfmBOorzCwD21H3V4f1mGuPqglJHDpXeu5D04XhBZHCSfjuW07123nNy
    Helicobacter pylori is a type of bacteria that infects the stomach. It is the most common cause of gastritis and peptic ulcers. It can also cause stomach cancer. There are typically no symptoms with infection, but symptoms may include indigestion and pain in the upper abdomen. […] H. pylori infection is usually asymptomatic, but it can erode the protective coating lining the stomach, causing inflammation that leads to gastritis or peptic ulcers. […] Peptic ulcers can cause intermittent dull or burning abdominal pain that lasts minutes to hours, for days or weeks at a time. These ulcers can also cause nausea, bloating, and unintentional weight loss. […] Researchers aren’t sure how H. pylori is transmitted, but it could be spread through unclean water and food, or through contact with infected bodily fluids such as saliva. It’s also unclear why some people develop symptoms, while others don’t.
  • #47 Helicobacter pylori | healthdirect
    https://www.healthdirect.gov.au/helicobacter-pylori
    Helicobacter pylori (H. pylori) is a type of bacterium that can live in the lining of the stomach. […] H. pylori can cause stomach inflammation (gastritis) and more serious conditions such as stomach ulcers and stomach cancer. […] Many Australians carry the bacteria without it causing any symptoms. […] If you have symptoms, they may include: a burning feeling in your upper stomach area (like heartburn) which may change with eating, indigestion or full feeling before you have finished eating, nausea and vomiting, bloating and burping, loss of appetite. […] Nearly everyone who has H. pylori gets gastritis (inflammation of the stomach lining). This leads to increased stomach acid production. If you experience symptoms, it’s known as H. pylori-associated dyspepsia (indigestion). […] Because your stomach produces more acid than usual, you are more likely to develop open sores in the stomach (gastric ulcers). If these occur in the upper part of the small intestine they are known as duodenal ulcers. […] H. pylori also increases the risk of certain stomach cancers. Fortunately, treating and removing H. pylori infection heals most sores and reduces the risk.
  • #48 H. pylori Patient Resources | Meridian Bioscience
    https://www.meridianbioscience.com/h-pylori-patients-resources/
    Suffering from heartburn, indigestion, stomach pain? These symptoms are usually blamed on things such as stress, diet, or lifestyle choices. When symptoms dont go away and disrupt your daily life, it could be something more serious called a Helicobacter pylori infection; also known as H. pylori. […] There is no single symptom of H. pylori. Common symptoms include: stomach or abdominal discomfort, stomach or abdominal pain, bloating, nausea, regurgitation, heartburn, flatulence, belching. […] Helicobacter pylori, commonly referred to as H. pylori, is a bacteria (germ) that lives in the lining of the stomach and its one of the worlds most common bacterial infections. […] There are simple ways to diagnose and treat H. pylori. When H. pylori infections are not diagnosed and treated by a doctor, they can cause sores in the lining of the stomach known as ulcers.
  • #49 Helicobacter Pylori | Dr Melissa White | Sunshine Coast Gastroenterologist
    https://www.melissawhitegastro.com.au/articles/helicobacter-pylori
    H.Pylori can also be the cause of different types of stomach or gastric ulcers. An ulcer is a break in the lining of the stomach or upper bowel (the duodenum). Ulcers occurring in these areas are often called peptic ulcers. H.Pylori is the cause of about 90% of ulcers in the duodenum. The common symptom is pain in the upper part of the abdomen. However, it is important to recognise that pain is often not due to ulcers as some ulcers cause no symptoms. A small proportion of ulcers cause serious complications such as bleeding or perforation (bursting). […] H.Pylori is also the cause of about 70% of stomach ulcers. Most of the remaining 30% are due to drugs taken for arthritis (non-steroidal anti-inflammatory drugs), or aspirin taken to prevent heart attacks or strokes. Some patients have both risk factors. The symptoms and complications of stomach ulcers are the same as for duodenal ulcers. Modern anti-ulcer drugs heal virtually all duodenal and stomach ulcers but there is a high chance that the ulcer will come back if H.Pylori is not eradicated. If H.Pylori infection is cured, the risk of the ulcer returning is very low, unless aspirin or anti-inflammatory drugs need to be taken.
  • #50 Learn About The Helicobacter Pylori | Sydney Gut Clinic
    https://sydneygutclinic.com/what-you-need-to-know-about-helicobacter-pylori-infection-and-treatment/
    Helicobacter pylori, or more commonly known as H. pylori, is a bacteria found in the human digestive tract that infects more than half of the worlds adult population. […] While generally harmless, the bacteria can affect the stomach lining, which is the layer that protects the stomach from acid involved in the digestion of food. This can lead to ulcers and sores in the stomach and the small intestine. […] In very rare cases, an H. pylori infection may even lead to stomach cancer. […] The infection itself doesnt cause any symptoms. Most people with the infection might not even develop any symptoms at all. […] When H. pylori bacteria cause ulcers in the stomach, on the other hand, patients may start to experience symptoms. […] The most common symptom is a dull pain or a burning pain in the stomach, which patients may experience between meals or when the stomach is empty. The pain might ease after meals or taking antacids.
  • #51 H.Pylori Infection (Stomach Ulcer) – Alpha Digestive & Liver Centre
    https://alphagastro.sg/conditions/hpylori-infection/
    H. pylori infection is a significant risk factor for certain types of stomach cancer. […] Infection by a type of bacteria called Helicobacter pylori (H. pylori) affects the lining of the stomach and duodenum and can result in symptoms such as indigestion and pain and discomfort in the upper abdomen. […] If left untreated in the long run, H.pylori can increase ones likelihood of developing stomach cancer.