Alergia na leki
Charakterystyka, pielęgnacja i opieka
Alergia na leki to immunologiczna nadwrażliwość, w której układ odpornościowy wytwarza specyficzne przeciwciała przeciwko lekom, błędnie identyfikując je jako zagrożenie. Objawy mogą pojawić się natychmiast lub z opóźnieniem i obejmują wysypkę, pokrzywkę, świąd, obrzęk, gorączkę, a w najcięższych przypadkach anafilaksję z objawami takimi jak trudności w oddychaniu, obrzęk gardła, spadek ciśnienia krwi i utrata przytomności. Diagnostyka opiera się na szczegółowym wywiadzie, badaniu fizykalnym oraz testach skórnych i krwiowych, a w razie wątpliwości na testach prowokacyjnych. Kluczowe jest rozróżnienie prawdziwej alergii (stanowiącej 5-10% niepożądanych reakcji) od innych działań niepożądanych. W leczeniu łagodnych objawów stosuje się leki przeciwhistaminowe, niesteroidowe leki przeciwzapalne i kortykosteroidy, natomiast anafilaksja wymaga natychmiastowego podania epinefryny i hospitalizacji.
- Wprowadzenie do alergii na leki
- Objawy alergii na leki
- Diagnostyka alergii na leki
- Pielęgniarskie diagnozy w alergii na leki
- Zmniejszony rzut serca
- Nieskuteczne oczyszczanie dróg oddechowych
- Upośledzenie spontanicznej wentylacji
- Deficyt wiedzy
- Ryzyko wystąpienia reakcji niepożądanej
- Opieka pielęgniarska nad pacjentem z alergią na leki
- Ocena ryzyka i zapobieganie
- Rozpoznanie i interwencja w reakcji alergicznej
- Monitorowanie pacjenta
- Leczenie reakcji alergicznej
- Edukacja pacjenta i rodziny
- Dokumentacja i komunikacja
- Specjalne aspekty opieki pielęgniarskiej
- Wyzwania w opiece nad pacjentem z alergią na leki
- Niewłaściwe oznaczenie alergii na leki
- Reakcje krzyżowe między lekami
- Znaczenie komunikacji w zespole medycznym
- Oczekiwane wyniki opieki pielęgniarskiej
- Podsumowanie roli pielęgniarskiej w opiece nad pacjentem z alergią na leki
Wprowadzenie do alergii na leki
Alergia na leki to nadmierna reakcja układu immunologicznego na substancję zawartą w leku. Występuje, gdy układ odpornościowy mylnie identyfikuje lek jako szkodliwą substancję, taką jak wirus czy bakteria, i produkuje przeciwciała specyficzne dla tego leku. Przy kolejnym podaniu leku, przeciwciała te rozpoznają lek i kierują ataki układu odpornościowego na tę substancję12. Alergia na leki może wystąpić po przyjęciu leków dostępnych bez recepty, leków na receptę lub preparatów ziołowych3.
Prawdziwa alergia na leki nie jest powszechna – szacuje się, że mniej niż 5-10% niepożądanych reakcji na leki jest spowodowanych rzeczywistą alergią. Pozostałe przypadki to działania niepożądane leku, które nie mają podłoża alergicznego4. Pomimo to, prawidłowe rozpoznanie i zarządzanie alergią na leki ma kluczowe znaczenie dla bezpieczeństwa pacjenta.
Objawy alergii na leki
Objawy alergii na leki mogą wystąpić natychmiast lub w ciągu kilku godzin po podaniu leku. W niektórych przypadkach reakcje, szczególnie wysypki, mogą pojawić się po kilku godzinach, dniach lub nawet tygodniach5. Do najczęstszych objawów alergii na leki należą wysypka, pokrzywka i gorączka6.
Objawy alergii na leki można podzielić na łagodne do umiarkowanych oraz ciężkie:
Objawy łagodne do umiarkowanych
- Wysypka skórna
- Pokrzywka (czerwone, uniesione, swędzące plamy na skórze)
- Świąd
- Obrzęk warg, twarzy lub oczu
- Ból brzucha lub wymioty
- Katar
- Swędzące, łzawiące oczy
- Gorączka
Objawy ciężkie (anafilaksja)
Najpoważniejszym typem reakcji alergicznej jest anafilaksja, która może obejmować:
- Trudności w oddychaniu, świszczący oddech
- Obrzęk gardła i języka
- Trudności w przełykaniu
- Nagłe osłabienie lub zawroty głowy
- Przyspieszone bicie serca
- Spadek ciśnienia krwi
- Utrata przytomności
- Uczucie zbliżającej się katastrofy
Objawy anafilaksji mogą rozwinąć się w ciągu minut po przyjęciu leku i mogą bezpośrednio zagrażać życiu11. Najcięższe reakcje alergiczne na leki zwykle występują, gdy lek jest podawany w formie zastrzyku lub dożylnie12.
Diagnostyka alergii na leki
Dokładna diagnoza jest niezbędna w przypadku podejrzenia alergii na leki. Proces diagnostyczny obejmuje zazwyczaj badanie fizykalne i szczegółowy wywiad medyczny13. Kluczowe znaczenie ma zebranie szczegółowych informacji na temat wszystkich leków przyjmowanych przez pacjenta, w tym dokładny opis objawów, czas ich wystąpienia i liczbę dawek każdego leku przyjętego przed wystąpieniem reakcji14.
W zależności od wywiadu lekarskiego, lekarz może zlecić dodatkowe badania lub skierować pacjenta do alergologa w celu przeprowadzenia specjalistycznych testów15. Metody diagnostyczne mogą obejmować:
Testy skórne
Testy skórne są często wykonywane w celu potwierdzenia lub wykluczenia alergii na leki. Pozytywny wynik sugeruje możliwość wystąpienia alergii na lek, natomiast wynik negatywny nie jest tak jednoznaczny16. Testy skórne są szczególnie przydatne w przypadku alergii na penicylinę, gdzie istnieją standaryzowane procedury testowe17.
Testy krwi
Badania krwi mogą być pomocne w niektórych przypadkach, choć nie zawsze są dostępne dla wszystkich leków18.
Testy prowokacyjne z lekiem
Jeśli diagnoza alergii na lek jest niepewna i lekarz oceni, że alergia jest mało prawdopodobna, można rozważyć stopniowaną próbę podania leku (test prowokacyjny)19. Podczas takiego testu pacjent otrzymuje małą, stopniowo zwiększaną dawkę podejrzanego leku pod ścisłą kontrolą medyczną i jest monitorowany pod kątem objawów reakcji alergicznej20.
Po przeanalizowaniu objawów i wyników badań, lekarz zazwyczaj może ustalić, czy pacjent ma alergię na dany lek21. Ważne jest, aby dokładnie udokumentować reakcję alergiczną na lek, co pozwoli uniknąć niepewności w przyszłości i w wielu przypadkach umożliwi przepisanie alternatywnego leku, który nie wchodzi w reakcje krzyżowe z oryginalnym związkiem22.
Pielęgniarskie diagnozy w alergii na leki
Odpowiednie diagnozy pielęgniarskie są kluczowe dla efektywnej opieki nad pacjentem z alergią na leki, szczególnie w przypadku wystąpienia reakcji anafilaktycznej. Na podstawie zebranych danych z oceny stanu pacjenta, można wyróżnić następujące diagnozy pielęgniarskie:
Zmniejszony rzut serca
Zmniejszony rzut serca związany z anafilaksją może być spowodowany znacznym zmniejszeniem napięcia żylnego i przesiękiem płynów, wyciekiem histaminy powodującym wyciek płynów z naczyń krwionośnych do tkanek oraz rozszerzeniem naczyń23. Objawy mogą obejmować zaburzenia rytmu serca, spadek ciśnienia krwi i utratę przytomności.
Nieskuteczne oczyszczanie dróg oddechowych
Nieskuteczne oczyszczanie dróg oddechowych związane z anafilaksją może być spowodowane skurczem dróg oddechowych oraz obrzękiem krtani, prowadzącym do zwężenia dróg oddechowych i zmniejszonego natlenienia24. Pacjent może doświadczać trudności w oddychaniu, świszczącego oddechu i uczucia duszności.
Upośledzenie spontanicznej wentylacji
Anafilaksja może szybko zagrażać życiu, jeśli nie zostanie rozpoznana lub leczona natychmiast, powodując niedrożność dróg oddechowych wymagającą intubacji i wentylacji25. Monitorowanie stanu układu oddechowego pacjenta jest kluczowe dla wczesnego wykrywania i interwencji.
Deficyt wiedzy
Deficyt wiedzy związany z anafilaksją może prowadzić do niezrozumienia czynników wyzwalających, objawów, zapobiegania i zarządzania stanem26. Edukacja pacjenta jest niezbędna, aby mógł on rozpoznać wczesne objawy reakcji alergicznej i podjąć odpowiednie działania.
Ryzyko wystąpienia reakcji niepożądanej
Ta diagnoza nie jest potwierdzona objawami, ponieważ problem jeszcze nie wystąpił. Interwencje pielęgniarskie mają na celu zapobieganie27. Istotne jest identyfikowanie pacjentów z wysokim ryzykiem alergii na leki i wdrażanie odpowiednich środków ostrożności.
Opieka pielęgniarska nad pacjentem z alergią na leki
Pielęgniarki odgrywają kluczową rolę w zarządzaniu i zapobieganiu alergii na leki. Ich działania obejmują szereg interwencji mających na celu zapewnienie bezpieczeństwa pacjenta i efektywne leczenie reakcji alergicznych.
Ocena ryzyka i zapobieganie
Pielęgniarka ma istotną rolę w zapobieganiu anafilaksji i innych reakcji alergicznych na leki28. Do kluczowych działań należą:
- Ocena wszystkich pacjentów pod kątem alergii lub wcześniejszych reakcji na leki
- Ocena zrozumienia przez pacjenta wcześniejszych reakcji i kroków podjętych przez pacjenta i rodzinę w celu zapobiegania dalszej ekspozycji na alergeny
- Informowanie pacjenta o noszeniu lub posiadaniu identyfikacji, która wymienia konkretny alergen, gdy zidentyfikowane zostaną nowe alergie
Ważne jest również rozpoznanie pacjentów z wysokim ryzykiem reakcji alergicznych na leki. Do zmiennych klinicznych zwiększających ryzyko należą: osobisty wywiad alergii na leki, zespół wielorakiej alergii, obecność infekcji Epsteina-Barr lub HIV, lub współistniejąca astma30.
Rozpoznanie i interwencja w reakcji alergicznej
Wczesne rozpoznanie objawów reakcji alergicznej jest kluczowe dla skutecznej interwencji. Jeśli pielęgniarka podejrzewa, że pacjent doświadcza wczesnych objawów ostrej reakcji nadwrażliwości, powinna niezwłocznie wdrożyć interwencje awaryjne31:
- ZATRZYMAĆ infuzję, ale utrzymać dostęp dożylny
- WEZWAĆ lekarza
- OCENIĆ dalej pacjenta: zebrać parametry życiowe, użyć pulsoksymetru do pomiaru saturacji tlenem, osłuchać szmery oddechowe i sprawdzić progresję objawów
- PRZYGOTOWAĆ się do leczenia awaryjnego, w tym potencjalnej potrzeby podania płynów dożylnych, tlenu i leków resuscytacyjnych
Monitorowanie pacjenta
Pacjenci z ciężką reakcją alergiczną na lek wymagają regularnego monitorowania parametrów życiowych i objawów. Ciągłe monitorowanie opieki pozwala personelowi medycznemu szybko reagować na reakcje anafilaktyczne i ciężkie objawy34. Po początkowym zdarzeniu potrzebna będzie opieka wspierająca i ścisłe monitorowanie przez kilka godzin, aby upewnić się, że objawy nie powrócą35.
Kluczowe aspekty monitorowania pacjenta obejmują:
- Ocenę drożności dróg oddechowych i obrabianie pacjenta pod kątem uczucia zwężenia dróg oddechowych
- Monitorowanie stanu natlenienia, w tym saturacji tlenem i wartości gazometrii krwi tętniczej
- Regularne pomiary parametrów życiowych (ciśnienie krwi, tętno, częstość oddechów)
- Obserwację pod kątem nawrotu objawów
Leczenie reakcji alergicznej
Leczenie alergii na leki można podzielić na dwie ogólne strategie: leczenie obecnych objawów alergii oraz zaprzestanie stosowania leku37. W zależności od nasilenia reakcji alergicznej, dostępne są różne opcje leczenia:
Leczenie łagodnej do umiarkowanej reakcji
W przypadku łagodnych objawów, takich jak wysypka, pokrzywka czy świąd, lekarz może zalecić:
- Leki przeciwhistaminowe, które blokują działanie histaminy w organizmie
- Niesteroidowe leki przeciwzapalne, takie jak ibuprofen lub aspiryna
- Kortykosteroidy, które zmniejszają stan zapalny
Leczenie ciężkiej reakcji anafilaktycznej
Anafilaksja wymaga natychmiastowego podania epinefryny oraz opieki szpitalnej w celu utrzymania ciśnienia krwi i wspomagania oddychania40. Podstawą leczenia ostrej anafilaksji jest epinefryna, a opóźnione lub brak zastosowania epinefryny nadal stanowi problem, mimo że obecne wytyczne podkreślają znaczenie wczesnego podania41.
Leki przeciwhistaminowe i kortykosteroidy nie są skutecznymi lekami pierwszego rzutu w leczeniu anafilaksji. Wytyczne zalecają, aby leki przeciwhistaminowe i kortykosteroidy były stosowane tylko jako uzupełnienie epinefryny42.
Edukacja pacjenta i rodziny
Edukacja pacjenta i jego rodziny jest kluczowym elementem opieki pielęgniarskiej nad osobami z alergią na leki. Wszyscy pacjenci zagrożeni anafilaksją powinni otrzymać plan działania instruujący ich, jak zarządzać epizodem anafilaksji, w tym prawidłowe podanie epinefryny43.
Po wypisie ze szpitala pacjent i rodzina powinni otrzymać informacje na temat:
- Leków awaryjnych i planów, które należy rozważyć w przypadku nawrotu kryzysu
- Rozpoznawania objawów reakcji alergicznej
- Prawidłowego stosowania auto-injekcji epinefryny
- Znaczenia noszenia identyfikatora medycznego (bransoletka, wisiorek) informującego o alergii na leki
Szczególnie ważne jest, aby pacjent wiedział, że w przypadku ciężkiej reakcji alergicznej powinien zastosować auto-injektor epinefryny, a następnie natychmiast udać się na pogotowie, nawet jeśli czuje się lepiej po użyciu leku, ponieważ objawy mogą powrócić4647.
Dokumentacja i komunikacja
Dokładna dokumentacja i komunikacja są niezbędne w zarządzaniu alergią na leki. Dokumentacja powinna zawierać:
- Wyniki oceny, w tym częstość oddechów, charakter szmerów oddechowych
- Częstość, ilość i wygląd wydzielin
- Obecność sinicy
- Wyniki badań laboratoryjnych
- Poziom świadomości pacjenta
Ważne jest, aby wszyscy pracownicy opieki zdrowotnej, w tym dentyści i personel szpitala, byli świadomi alergii pacjenta na leki49. Pacjenci powinni być zachęcani do noszenia bransoletki lub wisiorka medycznego, który identyfikuje ich alergię, szczególnie jeśli są narażeni na ryzyko ciężkiej reakcji alergicznej50.
Specjalne aspekty opieki pielęgniarskiej
Desensytyzacja na leki
W niektórych przypadkach, gdy nie ma odpowiedniego alternatywnego leku dla pacjenta z alergią, może być konieczne przeprowadzenie desensytyzacji na lek51. Desensytyzacja to proces, w którym pacjent otrzymuje bardzo małe dawki leku zawierającego alergen. Układ odpornościowy stopniowo rozwija tolerancję na alergen, a dawka jest stopniowo zwiększana, aż organizm będzie mógł przyjąć lek bez reakcji52.
Desensytyzacja na lek może pomóc tylko wtedy, gdy pacjent przyjmuje lek codziennie53. Proces ten musi być przeprowadzany pod ścisłym nadzorem medycznym, a pielęgniarka odgrywa ważną rolę w monitorowaniu pacjenta i zarządzaniu potencjalnymi reakcjami.
Opieka nad dziećmi z alergią na leki
Opieka nad dziećmi z alergią na leki wymaga szczególnej uwagi. Rodzice i opiekunowie powinni zostać dokładnie poinstruowani o zarządzaniu alergią dziecka, w tym o:
- Rozpoznawaniu objawów reakcji alergicznej
- Prawidłowym stosowaniu auto-injekcji epinefryny
- Znaczeniu noszenia identyfikatora medycznego informującego o alergii dziecka
- Informowaniu wszystkich osób zajmujących się dzieckiem (w tym nauczycieli, opiekunów) o alergii
Zarządzanie ciężkimi alergiami u dzieci często wymaga regularnego stosowania leków zapobiegawczych, szczególnie u tych, którzy są narażeni na ryzyko reakcji anafilaktycznych56.
Opieka w warunkach szpitalnych
W warunkach szpitalnych pielęgniarki muszą być szczególnie czujne w identyfikowaniu i zarządzaniu alergiami na leki. Do ich obowiązków należy:
- Sprawdzanie historii alergii przed podaniem jakiegokolwiek leku
- Upewnienie się, że alergia na lek jest wyraźnie zidentyfikowana w dokumentacji medycznej pacjenta
- Zapewnienie, że pacjent nosi bransoletkę alergiczną podczas pobytu w szpitalu
- Monitorowanie pacjenta pod kątem objawów reakcji alergicznej po podaniu leku
Ważne jest również, aby pielęgniarki były uczciwe i zgłaszały wszelkie błędy w podawaniu leków, na które pacjent ma alergię. Błędy takie powinny być dokumentowane zgodnie z polityką placówki, a pacjent powinien być ściśle monitorowany pod kątem objawów reakcji alergicznej59.
Wyzwania w opiece nad pacjentem z alergią na leki
Niewłaściwe oznaczenie alergii na leki
Jednym z wyzwań w zarządzaniu alergią na leki jest niewłaściwe oznaczenie alergii. Często pacjenci są nieprawidłowo oznaczani jako alergiczni na penicylinę i dlatego odmawia się im korzyści z terapii β-laktamowej60. Obecność etykiety alergii na penicylinę znacznie zmniejsza opcje przepisywania dla dotkniętych nią pacjentów61.
Niektóre placówki zaczęły rozróżniać nietolerowane działania niepożądane od reakcji alergicznych. W elektronicznej dokumentacji medycznej, wszystko, co pacjent twierdzi, że ma jako „alergię”, jest wymienione. Następnie jest miejsce na ich reakcję (anafilaksja, pokrzywka, nudności itp.) – nawet jeśli nie kwalifikuje się to jako prawdziwa alergia62. To podejście może pomóc w identyfikacji pacjentów z prawdziwą alergią na leki i zapobiegać niepotrzebnemu unikaniu skutecznych leków.
Reakcje krzyżowe między lekami
Reakcje krzyżowe, termin używany w kontekście niepożądanych reakcji na leki, wyjaśnia sytuację, w której ktoś, kto jest uczulony na jeden lek, może również mieć reakcję alergiczną na inny, różny lek63. Pielęgniarki powinny być świadome potencjalnych reakcji krzyżowych między lekami i informować o tym pacjentów.
Przy wybieraniu alternatywnych leków należy brać pod uwagę reakcje krzyżowe między lekami. Gdy są dostępne, powinny być stosowane alternatywne leki o niespokrewnionych strukturach chemicznych64.
Znaczenie komunikacji w zespole medycznym
Jasna komunikacja z pracownikami opieki zdrowotnej jest ważna dla zarządzania stanem takim jak alergia na leki65. Grupa ekspertów zgodziła się, że dialog między pracownikiem opieki zdrowotnej a pacjentem, który miał podejrzaną lub potwierdzoną reakcję alergiczną, lub jego opiekunem, jest ważny, aby zapewnić możliwość zadawania pytań i zapewnienia zarówno uspokojenia, jak i praktycznych porad66.
Zalecenia dotyczące sprawdzania, czy pacjenci mają niezbędną wiedzę, oraz przekazywania pacjentom odpowiedzialności za noszenie i udostępnianie informacji o alergii na leki mają na celu zminimalizowanie obaw pacjentów, poprawę komunikacji między pacjentami, lekarzami i farmaceutami oraz umożliwienie pacjentowi lepszego zarządzania potwierdzoną lub podejrzewaną alergią na leki67.
Oczekiwane wyniki opieki pielęgniarskiej
Efektywna opieka pielęgniarska nad pacjentem z alergią na leki powinna prowadzić do osiągnięcia następujących wyników:
- Pacjent utrzyma skuteczny wzorzec oddychania, co będzie widoczne przez zrelaksowane oddychanie o normalnej częstości i głębokości oraz brak dodatkowych szmerów oddechowych68
- Pacjent i jego bliscy wyraźą zrozumienie reakcji alergicznej, jej zapobiegania i zarządzania69
- Pacjent będzie wiedział, jak stosować auto-iniektor epinefryny w przypadku nagłej reakcji alergicznej70
- Pacjent będzie nosił identyfikator medyczny informujący o jego alergii na leki71
- Pacjent będzie wiedział, jakich leków należy unikać i jakie są bezpieczne alternatywy72
Osiągnięcie tych wyników wymaga kompleksowego podejścia do opieki, które obejmuje dokładną ocenę, odpowiednie interwencje i ciągłą edukację pacjenta.
Podsumowanie roli pielęgniarskiej w opiece nad pacjentem z alergią na leki
Pielęgniarki odgrywają kluczową rolę w zarządzaniu alergią na leki na wszystkich etapach opieki nad pacjentem. Ich obowiązki obejmują:
- Ocenę ryzyka alergii na leki u wszystkich pacjentów
- Wczesne rozpoznanie objawów reakcji alergicznej i natychmiastową interwencję
- Podawanie odpowiednich leków zgodnie z zaleceniami lekarza
- Monitorowanie stanu pacjenta pod kątem skuteczności leczenia i nawrotu objawów
- Edukację pacjenta i rodziny na temat alergii na leki, jej zapobiegania i zarządzania
- Dokładną dokumentację reakcji alergicznych i komunikację z zespołem medycznym
- Wspieranie pacjenta w samodzielnym zarządzaniu alergią na leki po wypisie ze szpitala
Pielęgniarki muszą być świadome, że alergia na leki może mieć poważne konsekwencje, w tym ciężką astmę, anafilaksję, a nawet śmierć76. Muszą być przygotowane do szybkiego rozpoznania i reakcji na ciężkie reakcje alergiczne, które mogą rozwijać się w ciągu minut po ekspozycji na lek.
Kompetentna i współczująca opieka pielęgniarska może znacząco poprawić wyniki leczenia pacjentów z alergią na leki, zmniejszyć lęk związany z potencjalnymi reakcjami alergicznymi i poprawić jakość życia pacjentów z tym schorzeniem.
Kolejne rozdziały
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Wybierz kolejny rozdział z menu poniżej, aby otworzyć nową podstronę kompedium wiedzy i uzyskać szczegółowe informację o leku, substancji lub chorobie.
Materiały źródłowe
- #1 Drug allergy – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/drug-allergy/symptoms-causes/syc-20371835
A drug allergy happens when the immune system mistakenly identifies a medicine as a harmful substance, such as a virus or bacterium. […] Once the immune system detects a medicine as a harmful substance, it develops an antibody specific to that medicine. […] If you have a drug allergy, the best prevention is to avoid using the problem medicine. Steps you can take to protect yourself include the following: […] Be sure that your drug allergy is clearly identified in your medical records. Inform other healthcare professionals, such as your dentist or any medical specialist. […] Wear a medical alert bracelet that identifies your drug allergy. This information can ensure proper treatment in an emergency.
- #2 Drug allergy | UM Health-Sparrowhttps://www.uofmhealthsparrow.org/departments-conditions/conditions/drug-allergy
A drug allergy happens when the immune system mistakenly identifies a medicine as a harmful substance, such as a virus or bacterium. […] Once the immune system detects a medicine as a harmful substance, it develops an antibody specific to that medicine. […] The next time you take the medicine, these specific antibodies flag the medicine and direct immune system attacks on the substance. […] If a healthcare professional determines that you have a drug allergy or likely allergy stopping the medicine is the first step in treatment. […] Your health professional may prescribe an antihistamine or recommend a nonprescription antihistamine such as diphenhydramine (Benadryl). […] Anaphylaxis requires an immediate epinephrine shot. Hospital care also is needed to maintain blood pressure and support breathing.
- #3 Drug allergy – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/drug-allergy/symptoms-causes/syc-20371835
A drug allergy is the reaction of the immune system to a medicine. Any medicine over-the-counter, prescription or herbal can trigger a drug allergy. However, a drug allergy is more likely with certain medicines. […] The most common symptoms of drug allergy are hives, rash and fever. But a drug allergy also may cause serious reactions. This includes a severe, life-threatening condition known as anaphylaxis. […] Symptoms of a serious drug allergy often happen within an hour after taking a medicine. Other reactions, particularly rashes, can happen hours, days or weeks later. […] Call 911 or emergency medical help if you experience signs of a severe reaction or suspected anaphylaxis after taking a medicine. […] If you have milder symptoms of a drug allergy, see a healthcare professional as soon as possible.
- #4 Drug Allergy Basics: Causes, Symptoms, and Treatmentshttps://www.healthline.com/health/drug-allergy
A drug allergy is an allergic reaction to a medication. With an allergic reaction, your immune system, which fights infection and disease, reacts to the drug. This reaction can cause symptoms such as rash, fever, and trouble breathing. […] True drug allergy is not common. Less than 5 to 10 percent of negative drug reactions are caused by genuine drug allergy. The rest are side effects of the drug. All the same, its important to know if you have a drug allergy and what to do about it. […] Not always. The symptoms of a drug allergy may be so mild that you hardly notice them. You might experience nothing more than a slight rash. […] A severe drug allergy, however, can be life-threatening. It could cause anaphylaxis. Anaphylaxis is a sudden, life-threatening, whole-body reaction to a drug or other allergen. An anaphylactic reaction could occur minutes after you take the drug. In some cases, it could happen within 12 hours of taking the drug. Symptoms can include: irregular heartbeat, trouble breathing, swelling, unconsciousness.
- #5 Drug allergy – Symptoms and causes – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/drug-allergy/symptoms-causes/syc-20371835
A drug allergy is the reaction of the immune system to a medicine. Any medicine over-the-counter, prescription or herbal can trigger a drug allergy. However, a drug allergy is more likely with certain medicines. […] The most common symptoms of drug allergy are hives, rash and fever. But a drug allergy also may cause serious reactions. This includes a severe, life-threatening condition known as anaphylaxis. […] Symptoms of a serious drug allergy often happen within an hour after taking a medicine. Other reactions, particularly rashes, can happen hours, days or weeks later. […] Call 911 or emergency medical help if you experience signs of a severe reaction or suspected anaphylaxis after taking a medicine. […] If you have milder symptoms of a drug allergy, see a healthcare professional as soon as possible.
- #6 Drug allergy // Middlesex Healthhttps://middlesexhealth.org/learning-center/diseases-and-conditions/drug-allergy
A drug allergy is the reaction of the immune system to a medicine. […] The most common symptoms of drug allergy are hives, rash and fever. […] A drug allergy also may cause serious reactions. This includes a severe, life-threatening condition known as anaphylaxis. […] If you have milder symptoms of a drug allergy, see a healthcare professional as soon as possible. […] A drug allergy happens when the immune system mistakenly identifies a medicine as a harmful substance, such as a virus or bacterium. […] The next time you take the medicine, these specific antibodies flag the medicine and direct immune system attacks on the substance. […] If a healthcare professional determines that you have a drug allergy or likely allergy stopping the medicine is the first step in treatment. […] Anaphylaxis requires an immediate epinephrine shot. Hospital care also is needed to maintain blood pressure and support breathing.
- #7 Drug Allergy | Anaphylaxis UKhttps://www.anaphylaxis.org.uk/fact-sheet/drug-allergy/
There are different types of drug allergy. Here we focus on the type of reactions that come on very quickly and can lead to anaphylaxis. If you have symptoms you think might be caused by a drug, visit your GP or pharmacist. […] The symptoms of a drug allergy can come on quickly, within minutes of taking the drug. […] Mild to moderate symptoms may include: nettle rash (known as hives or urticaria) anywhere on the body a tingling or itchy feeling in the mouth swelling of lips, face or eyes stomach pain or vomiting. More serious symptoms are often referred to as the ABC symptoms and can include: AIRWAY – swelling in the throat, tongue or upper airways (tightening of the throat, hoarse voice, difficulty swallowing). BREATHING – sudden onset wheezing, breathing difficulty, noisy breathing. CIRCULATION – dizziness, feeling faint, sudden sleepiness, tiredness, confusion, pale clammy skin, loss of consciousness.
- #8 Drug Allergy | AAFA.orghttps://aafa.org/allergies/types-of-allergies/medicine-drug-allergy/
Common symptoms of an allergic reaction to a drug can include: Rash or hives, Itching, Breathing problems, Swelling, especially the face and tongue. […] […] A true drug allergy can cause a severe allergic reaction called anaphylaxis. Symptoms of anaphylaxis usually involve more than one part of the body such as the skin, mouth, eyes, lungs, heart, gut, and brain. Some symptoms include: Skin rashes, itching, and hives; Swelling of the lips, tongue, or throat; Shortness of breath, trouble breathing, wheezing (whistling sound during breathing); Stomach pain, vomiting, or diarrhea; Feeling like something awful is about to happen. […] […] The first-line treatment for anaphylaxis is epinephrine. You must treat anaphylaxis right away for the best chance for improvement and to prevent serious, potentially life-threatening complications. […] […] If you have an allergic reaction to a medicine, stop taking it and contact your doctor right away. […]
- #9 Drug Allergy: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/8621-medication-allergies
If you have a drug allergy, always inform a healthcare provider before undergoing any type of treatment, including dental care or surgical procedures. […] Go to the emergency room or call 911 or your local emergency number immediately if you have any symptoms of a severe allergic reaction. These symptoms include: Trouble breathing. Difficulty swallowing. Sudden weakness or lightheadedness. An accelerated heartbeat. Unconsciousness. Without treatment, your symptoms may be fatal.
- #10 Drug Allergy | AAFA.orghttps://aafa.org/allergies/types-of-allergies/medicine-drug-allergy/
Common symptoms of an allergic reaction to a drug can include: Rash or hives, Itching, Breathing problems, Swelling, especially the face and tongue. […] […] A true drug allergy can cause a severe allergic reaction called anaphylaxis. Symptoms of anaphylaxis usually involve more than one part of the body such as the skin, mouth, eyes, lungs, heart, gut, and brain. Some symptoms include: Skin rashes, itching, and hives; Swelling of the lips, tongue, or throat; Shortness of breath, trouble breathing, wheezing (whistling sound during breathing); Stomach pain, vomiting, or diarrhea; Feeling like something awful is about to happen. […] […] The first-line treatment for anaphylaxis is epinephrine. You must treat anaphylaxis right away for the best chance for improvement and to prevent serious, potentially life-threatening complications. […] […] If you have an allergic reaction to a medicine, stop taking it and contact your doctor right away. […]
- #11 Anaphylaxis: Recognition and Management | AAFPhttps://www.aafp.org/pubs/afp/issues/2020/0915/p355.html
Anaphylaxis is a life-threatening systemic reaction, normally occurring within one to two hours of exposure to an allergen. […] Coexisting asthma, mast cell disorders, older age, underlying cardiovascular disease, peanut and tree nut allergy, and drug-induced reactions are associated with severe or fatal anaphylactic reactions. […] Following an anaphylactic reaction, management should focus on developing an emergency action plan, referral to an allergist, and patient education on avoidance of triggers and appropriate use of an epinephrine auto-injector. […] The mainstay of treatment of acute IgE-mediated or nonimmune anaphylaxis is epinephrine. […] Delayed or lack of epinephrine use continues to be a problem despite current guidelines emphasizing the importance of early administration.
- #12 Drug Allergy to Medications | Allergy & Asthma Networkhttps://allergyasthmanetwork.org/allergies/drug-allergy/
If certain medications make your skin bloom with hives, cause light-headedness, nausea, difficulty breathing or stomach cramps, or make your throat or mouth swell, it could be the result of a drug allergy. Symptoms can begin within moments of ingesting a medication or up to several hours later. […] The most severe allergic reactions to medications usually happen when the medication is given as a shot or intravenously (directly into a vein). […] If you develop flushing or hives within a few hours of taking a medication, call a board-certified allergist. If symptoms are severe and involve multiple body organs a skin rash, respiratory problems and/or digestive issues it could be anaphylaxis. Call 911 and go to the emergency department immediately. Then you’ll need to schedule a visit with the allergist and get tested for a drug allergy.
- #13 Drug allergy – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/drug-allergy/diagnosis-treatment/drc-20371839
An accurate diagnosis is essential. […] A healthcare professional typically does a physical exam and asks you questions. […] Your health professional may order more tests or refer you to an allergy specialist, called an allergist, for tests. […] A positive result suggests that you may have a drug allergy. […] A negative result isn’t as clear-cut. […] After looking at your symptoms and test results, a healthcare professional can usually reach one of the following conclusions: You have a drug allergy. […] Treatments for a drug allergy can be divided into two general strategies: Treatment for present allergy symptoms. […] Stopping the medicine. If a healthcare professional determines that you have a drug allergy or likely allergy stopping the medicine is the first step in treatment.
- #14 Drug Allergy – BSACISearch iconSearch iconhttps://www.bsaci.org/resources/allergy-management/drug-allergy/
The term drug allergy should be considered to encompass any reaction due to a drug that has clinical features compatible with hypersensitivity. Therefore, anyone presenting with a rash, angioedema, bronchospasm, hypotension should be considered to have drug allergy regardless of the nature of the underlying mechanism. […] The investigation of drug allergy relies heavily on a detailed clinical history which must include a description of the rash, the onset of symptoms and the number of doses of each drug taken before the reaction starts. Therefore, documentation of an acute drug-allergic reaction is key to accurate identification of the culprit. The NICE drug allergy guideline (CG183 2014) provides guidance on documentation and recommends that the patient receives written communication detailing the nature of their drug allergy and a list of drugs to avoid. It is essential that all primary and secondary care organisations incorporate a template onto their electronic patient record systems in order to fulfil the requirements for documentation and communication of drug allergy.
- #15 Drug allergy – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/drug-allergy/diagnosis-treatment/drc-20371839
An accurate diagnosis is essential. […] A healthcare professional typically does a physical exam and asks you questions. […] Your health professional may order more tests or refer you to an allergy specialist, called an allergist, for tests. […] A positive result suggests that you may have a drug allergy. […] A negative result isn’t as clear-cut. […] After looking at your symptoms and test results, a healthcare professional can usually reach one of the following conclusions: You have a drug allergy. […] Treatments for a drug allergy can be divided into two general strategies: Treatment for present allergy symptoms. […] Stopping the medicine. If a healthcare professional determines that you have a drug allergy or likely allergy stopping the medicine is the first step in treatment.
- #16 Drug allergy – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/drug-allergy/diagnosis-treatment/drc-20371839
An accurate diagnosis is essential. […] A healthcare professional typically does a physical exam and asks you questions. […] Your health professional may order more tests or refer you to an allergy specialist, called an allergist, for tests. […] A positive result suggests that you may have a drug allergy. […] A negative result isn’t as clear-cut. […] After looking at your symptoms and test results, a healthcare professional can usually reach one of the following conclusions: You have a drug allergy. […] Treatments for a drug allergy can be divided into two general strategies: Treatment for present allergy symptoms. […] Stopping the medicine. If a healthcare professional determines that you have a drug allergy or likely allergy stopping the medicine is the first step in treatment.
- #17 Drug Allergy Clinic | Vanderbilt Health Nashville, TNhttps://www.vanderbilthealth.com/clinic/drug-allergy-clinic
Our clinic provides personalized testing and care for people with drug and medication allergies. An inaccurate drug allergy diagnosis can create problems with your medical care. Knowing your medication allergies can help ensure you receive the best possible care. […] Many people who have been told they are allergic to a certain medication may not actually be allergic to it. They may have had a one-time reaction, may have been allergic to an ingredient that is no longer used in that drug or may have outgrown the allergy. An inaccurate drug allergy diagnosis can create problems with your medical care. Our experts diagnose whether you have a true drug allergy and, if so, what to do about it. […] We offer a full range of tests, treatments and services, including: Blood tests, Desensitization, Education and materials about avoiding or substituting certain medications, Medical history assessment, Medication challenges, Patch testing, Pharmacogenomic testing, Skin testing.
- #18 Drug Allergy Clinic | Vanderbilt Health Nashville, TNhttps://www.vanderbilthealth.com/clinic/drug-allergy-clinic
Our clinic provides personalized testing and care for people with drug and medication allergies. An inaccurate drug allergy diagnosis can create problems with your medical care. Knowing your medication allergies can help ensure you receive the best possible care. […] Many people who have been told they are allergic to a certain medication may not actually be allergic to it. They may have had a one-time reaction, may have been allergic to an ingredient that is no longer used in that drug or may have outgrown the allergy. An inaccurate drug allergy diagnosis can create problems with your medical care. Our experts diagnose whether you have a true drug allergy and, if so, what to do about it. […] We offer a full range of tests, treatments and services, including: Blood tests, Desensitization, Education and materials about avoiding or substituting certain medications, Medical history assessment, Medication challenges, Patch testing, Pharmacogenomic testing, Skin testing.
- #19 Drug allergy – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/drug-allergy/diagnosis-treatment/drc-20371839
Anaphylaxis requires an immediate epinephrine shot. […] If you have a confirmed drug allergy, a healthcare professional likely would not prescribe the medicine that causes a reaction unless it is necessary. […] With either strategy, your health professional provides careful supervision. […] If the diagnosis of a drug allergy is uncertain and a healthcare professional judges that an allergy is unlikely, a graded drug challenge may be an option. […] If it’s necessary for you to take a medicine that has caused an allergic reaction, your care professional may recommend a treatment called drug desensitization.
- #20 Latex & Drug Allergy Testing and Treatment | UPMC in Central Pa.https://www.upmc.com/services/south-central-pa/allergy-asthma-immunology/allergies/drug-latex
The allergy specialists at UPMC in central Pa. offer diagnostic testing and treatment for children and adults with latex allergies or drug allergies. […] Our specialists provide comprehensive treatment for latex allergies and allergies to drugs or medications. We offer a full range of diagnostic and treatment services to help you understand and manage your latex allergy or drug allergy, including: […] Diagnostic Tests for Drug Allergies […] Oral drug challenge is a test that is used to confirm or rule out a drug allergy. During the test, you will be given a small, gradually increasing amount of a suspected allergy-causing drug under medical supervision and be monitored for signs of an allergic reaction. […] Allergy medications. Some medications may be able to help control mild allergic reactions to medications or latex, but may not be suitable if you have a severe or life-threatening allergy.
- #21 Drug allergy – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/drug-allergy/diagnosis-treatment/drc-20371839
An accurate diagnosis is essential. […] A healthcare professional typically does a physical exam and asks you questions. […] Your health professional may order more tests or refer you to an allergy specialist, called an allergist, for tests. […] A positive result suggests that you may have a drug allergy. […] A negative result isn’t as clear-cut. […] After looking at your symptoms and test results, a healthcare professional can usually reach one of the following conclusions: You have a drug allergy. […] Treatments for a drug allergy can be divided into two general strategies: Treatment for present allergy symptoms. […] Stopping the medicine. If a healthcare professional determines that you have a drug allergy or likely allergy stopping the medicine is the first step in treatment.
- #22 Providing information and support to patients – Drug Allergy – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK274145/
Patients are often left bewildered following a suspected allergic reaction to a drug. […] Fear of experiencing a further reaction can be heightened by a lack of information and worsened if the original reaction was severe. […] A drug allergy may not have been responsible for the original reaction, and so if drug allergy is excluded it is equally important that this information is conveyed to the individual in order to provide reassurance and enable optimal treatment to be prescribed in future. […] Written information given to the patient at the time of the reaction, with details of drug, number of doses and the nature and severity of the reaction will avoid uncertainty and in many cases allow prescription of an alternative drug not known to cross-react with the original compound. […] The importance of communication with patients who have had a suspected or confirmed drug allergy was highlighted by studies which described the fear of having a repeat reaction and the anxiety experienced by parents of children with a suspected drug allergy.
- #23 Anaphylaxis: Nursing Diagnoses & Care Plans | NurseTogetherhttps://www.nursetogether.com/anaphylaxis-nursing-diagnosis-care-plan/
Anaphylaxis requires prompt rapid diagnosis and care since cardiac or respiratory arrest and death can occur. […] Initial management includes removal of the trigger, administering epinephrine as soon as possible, and managing the airway. […] It is crucial to provide health teaching with an epinephrine auto-injector on how to use it. […] Once the nurse identifies nursing diagnoses for anaphylaxis, nursing care plans help prioritize assessments and interventions for both short and long-term goals of care. […] Decreased cardiac output associated with anaphylaxis can be caused by decreased preload due to a severe decrease in venous tone and fluid extravasation, histamine leakage causing blood vessels to leak fluid into the tissues, and vasodilation. […] Nursing Diagnosis: Decreased Cardiac Output
- #24 Anaphylaxis: Nursing Diagnoses & Care Plans | NurseTogetherhttps://www.nursetogether.com/anaphylaxis-nursing-diagnosis-care-plan/
Nursing Diagnosis: Deficient Knowledge […] Deficient knowledge associated with anaphylaxis can result in a misunderstanding of triggers, symptoms, prevention, and management. […] Nursing Diagnosis: Impaired Spontaneous Ventilation […] Anaphylaxis can become life-threatening quickly if not recognized or treated immediately, causing airway obstruction requiring intubation and ventilation. […] Nursing Diagnosis: Ineffective Airway Clearance […] Ineffective airway clearance associated with anaphylaxis can be caused by airway spasms and laryngeal edema or swelling, leading to airway constriction and decreased oxygenation. […] Nursing Diagnosis: Risk for Adverse Reaction […] A risk diagnosis is not evidenced by signs and symptoms as the problem has not yet occurred. Nursing interventions are aimed at prevention.
- #25 Anaphylaxis: Nursing Diagnoses & Care Plans | NurseTogetherhttps://www.nursetogether.com/anaphylaxis-nursing-diagnosis-care-plan/
Nursing Diagnosis: Deficient Knowledge […] Deficient knowledge associated with anaphylaxis can result in a misunderstanding of triggers, symptoms, prevention, and management. […] Nursing Diagnosis: Impaired Spontaneous Ventilation […] Anaphylaxis can become life-threatening quickly if not recognized or treated immediately, causing airway obstruction requiring intubation and ventilation. […] Nursing Diagnosis: Ineffective Airway Clearance […] Ineffective airway clearance associated with anaphylaxis can be caused by airway spasms and laryngeal edema or swelling, leading to airway constriction and decreased oxygenation. […] Nursing Diagnosis: Risk for Adverse Reaction […] A risk diagnosis is not evidenced by signs and symptoms as the problem has not yet occurred. Nursing interventions are aimed at prevention.
- #26 Anaphylaxis: Nursing Diagnoses & Care Plans | NurseTogetherhttps://www.nursetogether.com/anaphylaxis-nursing-diagnosis-care-plan/
Nursing Diagnosis: Deficient Knowledge […] Deficient knowledge associated with anaphylaxis can result in a misunderstanding of triggers, symptoms, prevention, and management. […] Nursing Diagnosis: Impaired Spontaneous Ventilation […] Anaphylaxis can become life-threatening quickly if not recognized or treated immediately, causing airway obstruction requiring intubation and ventilation. […] Nursing Diagnosis: Ineffective Airway Clearance […] Ineffective airway clearance associated with anaphylaxis can be caused by airway spasms and laryngeal edema or swelling, leading to airway constriction and decreased oxygenation. […] Nursing Diagnosis: Risk for Adverse Reaction […] A risk diagnosis is not evidenced by signs and symptoms as the problem has not yet occurred. Nursing interventions are aimed at prevention.
- #27 Anaphylaxis: Nursing Diagnoses & Care Plans | NurseTogetherhttps://www.nursetogether.com/anaphylaxis-nursing-diagnosis-care-plan/
Nursing Diagnosis: Deficient Knowledge […] Deficient knowledge associated with anaphylaxis can result in a misunderstanding of triggers, symptoms, prevention, and management. […] Nursing Diagnosis: Impaired Spontaneous Ventilation […] Anaphylaxis can become life-threatening quickly if not recognized or treated immediately, causing airway obstruction requiring intubation and ventilation. […] Nursing Diagnosis: Ineffective Airway Clearance […] Ineffective airway clearance associated with anaphylaxis can be caused by airway spasms and laryngeal edema or swelling, leading to airway constriction and decreased oxygenation. […] Nursing Diagnosis: Risk for Adverse Reaction […] A risk diagnosis is not evidenced by signs and symptoms as the problem has not yet occurred. Nursing interventions are aimed at prevention.
- #28 Anaphylactic Shock Nursing Care Management and Study Guide – Nurseslabshttps://nurseslabs.com/anaphylactic-shock/
The nurse has an important role in preventing anaphylactic shock. […] The nurse must assess all patients for allergies or previous reactions to antigens. […] The nurse must also assess the patients understanding of previous reactions and steps taken by the patient and the family to prevent further exposure to antigens. […] When new allergies are identified, the nurse advises the patient to wear or carry identification that names the specific allergen or antigen. […] Based on the assessment data, the nursing diagnoses appropriate for the patient are: Impaired gas exchange related to ventilation perfusion imbalance. […] The major goals for a patient with anaphylactic shock are: Client will maintain an effective breathing pattern, as evidenced by relaxed breathing at normal rate and depth and absence of adventitious breath sounds.
- #29 Anaphylactic Shock Nursing Care Management and Study Guide – Nurseslabshttps://nurseslabs.com/anaphylactic-shock/
The nurse has an important role in preventing anaphylactic shock. […] The nurse must assess all patients for allergies or previous reactions to antigens. […] The nurse must also assess the patients understanding of previous reactions and steps taken by the patient and the family to prevent further exposure to antigens. […] When new allergies are identified, the nurse advises the patient to wear or carry identification that names the specific allergen or antigen. […] Based on the assessment data, the nursing diagnoses appropriate for the patient are: Impaired gas exchange related to ventilation perfusion imbalance. […] The major goals for a patient with anaphylactic shock are: Client will maintain an effective breathing pattern, as evidenced by relaxed breathing at normal rate and depth and absence of adventitious breath sounds.
- #30 Acute Hypersensitivity Reactions: What Nurses Need to Know – Johns Hopkins School of Nursinghttps://nursing.jhu.edu/magazine/articles/2011/04/acute-hypersensitivity-reactions-what-nurses-need-to-know/
Finally, PREPARE for emergency treatment, including the potential need to administer IV fluids, oxygen, and resuscitative medications. […] An acute HSR is a frightening experience. […] After the initial event, supportive care and close monitoring will be needed for several hours to ensure that symptoms do not recur. […] Recognizing high-risk patients and situations is an essential first step in reducing HSR morbidity and mortality. […] Clinical variables known to increase risk for HSRs include personal history of drug allergy, multiple allergy syndrome, presence of Epstein-Barr or HIV infection, or concurrent asthma. […] For high-risk medications, premedications with antihistamines and corticosteroids are widely used. […] An acute HSR is also an adverse drug reaction (ADR) and should be reported according to your organization’s policies. […] Enhanced reporting of ADRs will assist in defining true incidences of drug reactions. […] Readily available emergency supplies and medications can minimize the adverse outcomes of severe HSRs.
- #31 Acute Hypersensitivity Reactions: What Nurses Need to Know – Johns Hopkins School of Nursinghttps://nursing.jhu.edu/magazine/articles/2011/04/acute-hypersensitivity-reactions-what-nurses-need-to-know/
An acute hypersensitivity reaction is a rare but serious complication of exposure to foods, natural-rubber latex, medications, and other antigens. […] Nurses and nurse practitioners must recognize HSR risk factors, read early signs and symptoms, and intervene to protect the patient from further harm. […] Oncology nurses are particularly likely to witness HSRs from antimicrobials, biological and chemotherapeutic agents. […] All chemotherapy has the potential to cause an HSR. […] If you suspect your patient is experiencing early symptoms of an acute HSR, don’t hesitate to implement your emergency interventions. […] STOP the infusion but maintain IV access. […] CALL the provider. […] ASSESS your patient further: collect vital signs, use a pulse oximeter to obtain oxygen saturation, listen to breath sounds, and check for symptom progression.
- #32 Acute Hypersensitivity Reactions: What Nurses Need to Know – Johns Hopkins School of Nursinghttps://nursing.jhu.edu/magazine/articles/2011/04/acute-hypersensitivity-reactions-what-nurses-need-to-know/
An acute hypersensitivity reaction is a rare but serious complication of exposure to foods, natural-rubber latex, medications, and other antigens. […] Nurses and nurse practitioners must recognize HSR risk factors, read early signs and symptoms, and intervene to protect the patient from further harm. […] Oncology nurses are particularly likely to witness HSRs from antimicrobials, biological and chemotherapeutic agents. […] All chemotherapy has the potential to cause an HSR. […] If you suspect your patient is experiencing early symptoms of an acute HSR, don’t hesitate to implement your emergency interventions. […] STOP the infusion but maintain IV access. […] CALL the provider. […] ASSESS your patient further: collect vital signs, use a pulse oximeter to obtain oxygen saturation, listen to breath sounds, and check for symptom progression.
- #33 Acute Hypersensitivity Reactions: What Nurses Need to Know – Johns Hopkins School of Nursinghttps://nursing.jhu.edu/magazine/articles/2011/04/acute-hypersensitivity-reactions-what-nurses-need-to-know/
Finally, PREPARE for emergency treatment, including the potential need to administer IV fluids, oxygen, and resuscitative medications. […] An acute HSR is a frightening experience. […] After the initial event, supportive care and close monitoring will be needed for several hours to ensure that symptoms do not recur. […] Recognizing high-risk patients and situations is an essential first step in reducing HSR morbidity and mortality. […] Clinical variables known to increase risk for HSRs include personal history of drug allergy, multiple allergy syndrome, presence of Epstein-Barr or HIV infection, or concurrent asthma. […] For high-risk medications, premedications with antihistamines and corticosteroids are widely used. […] An acute HSR is also an adverse drug reaction (ADR) and should be reported according to your organization’s policies. […] Enhanced reporting of ADRs will assist in defining true incidences of drug reactions. […] Readily available emergency supplies and medications can minimize the adverse outcomes of severe HSRs.
- #34 Effective Management of Severe Drug Allergy Rasheshttps://www.beckerentandallergy.com/blog/managing-severe-drug-allergy-rashes
In severe cases like an anaphylactic reaction, quick and decisive action is crucial. Epinephrine is the primary treatment for this life-threatening allergic reaction. […] Patients with a severe drug allergy rash need to have their vital signs and symptoms monitored regularly. Continuous care monitoring allows health professionals to quickly respond to anaphylactic reactions and severe symptoms. […] Managing drug allergy rashes involves taking steps to prevent future reactions. For those with severe allergies, it’s vital to avoid triggers. […] Creating an allergy action plan is essential for people who might experience anaphylactic reactions. […] For those dealing with severe drug allergy rash, ongoing check-ups with an allergy specialist are essential. […] Regular contact with a healthcare provider is crucial for keeping an emergency action plan current, which can include methods to avoid triggers and instructions for immediate care.
- #35 Acute Hypersensitivity Reactions: What Nurses Need to Know – Johns Hopkins School of Nursinghttps://nursing.jhu.edu/magazine/articles/2011/04/acute-hypersensitivity-reactions-what-nurses-need-to-know/
Finally, PREPARE for emergency treatment, including the potential need to administer IV fluids, oxygen, and resuscitative medications. […] An acute HSR is a frightening experience. […] After the initial event, supportive care and close monitoring will be needed for several hours to ensure that symptoms do not recur. […] Recognizing high-risk patients and situations is an essential first step in reducing HSR morbidity and mortality. […] Clinical variables known to increase risk for HSRs include personal history of drug allergy, multiple allergy syndrome, presence of Epstein-Barr or HIV infection, or concurrent asthma. […] For high-risk medications, premedications with antihistamines and corticosteroids are widely used. […] An acute HSR is also an adverse drug reaction (ADR) and should be reported according to your organization’s policies. […] Enhanced reporting of ADRs will assist in defining true incidences of drug reactions. […] Readily available emergency supplies and medications can minimize the adverse outcomes of severe HSRs.
- #36 Anaphylactic Shock Nursing Care Management and Study Guide – Nurseslabshttps://nurseslabs.com/anaphylactic-shock/
Nursing interventions for the patient are: Monitor clients airway. Assess the client for the sensation of a narrowed airway. […] Monitor the oxygenation status. Monitor oxygen saturation and arterial blood gas values. […] Expected patient outcomes include: Client maintained an effective breathing pattern. […] Client and significant others verbalized understanding of allergic reaction, its prevention, and management. […] Upon discharge, the patient and family need to learn about the following: Emergency medications. The nurse should provide information about emergency medications and plans that should be considered should a crisis reoccur. […] The focus of documentation include: Assessment findings including respiratory rate, character of breath sounds; frequency, amount, and appearance of secretions; presence of cyanosis; laboratory findings; and mentation level.
- #37 Drug allergy – Diagnosis and treatment – Mayo Clinichttps://www.mayoclinic.org/diseases-conditions/drug-allergy/diagnosis-treatment/drc-20371839
An accurate diagnosis is essential. […] A healthcare professional typically does a physical exam and asks you questions. […] Your health professional may order more tests or refer you to an allergy specialist, called an allergist, for tests. […] A positive result suggests that you may have a drug allergy. […] A negative result isn’t as clear-cut. […] After looking at your symptoms and test results, a healthcare professional can usually reach one of the following conclusions: You have a drug allergy. […] Treatments for a drug allergy can be divided into two general strategies: Treatment for present allergy symptoms. […] Stopping the medicine. If a healthcare professional determines that you have a drug allergy or likely allergy stopping the medicine is the first step in treatment.
- #38 Drug Allergies | Reactions, Symptoms & Treatment | ACAAI Public Websitehttps://acaai.org/allergies/allergic-conditions/drug-allergies/
Ask about related drugs that you should avoid. […] Ask about alternatives to the drug that caused your allergic reaction. […] Wear an emergency medical alert bracelet or necklace that identifies your allergy. […] Anaphylaxis is a severe, potentially life-threatening reaction that can simultaneously affect two or more organ systems (for instance, when there is both swelling and difficulty breathing, or vomiting and hives). […] If you are caring for someone who appears to be having a severe reaction to a drug, tell the emergency care team what drug was taken, when it was taken and what the dosage was. […] If your allergic reaction to a drug is not life-threatening, your allergist may give you: An antihistamine to counteract the allergic reaction. […] A nonsteroidal anti-inflammatory drug, such as ibuprofen or aspirin, or a corticosteroid to reduce inflammation.
- #39 Drug Allergy: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/8621-medication-allergies
Drug allergies are an allergic reaction to medications. Its when your bodys immune system overreacts to medications. Your body develops a sensitivity to one of the substances in the medication and remembers it as a harmful foreign invader, like bacteria or viruses. The next time you ingest that drug, your immune system releases antibodies to remove it from your body. […] A drug allergy can be deadly. If you or a loved one have severe drug allergy symptoms, including swelling of your tongue or throat, trouble breathing, a fast heartbeat, lightheadedness or unconsciousness, you must act quickly: Call 911 or your local emergency number. Go to your nearest emergency room (ER) as soon as possible. […] Your healthcare provider may recommend the following drug allergy treatments: Stop taking the drug. Once the drug leaves your body, your symptoms should start to fade. If youre taking the medication to treat a condition, your provider will prescribe another medicine that doesnt cause an allergic reaction. Antihistamines. Antihistamines block the effects of histamine in your body. Corticosteroids. Corticosteroids are anti-inflammatory drugs that help reduce the production of chemicals that cause inflammation. Bronchodilators. Bronchodilators are a type of medication that help relieve symptoms that affect your lungs. Epinephrine auto-injector (EpiPen). If you have severe medication allergies, your provider may prescribe this device. Epinephrine quickly reverses the symptoms of anaphylaxis. Your provider will explain when and how to use it. Allergy desensitization. During allergy desensitization, a provider gives you small amounts of medications that contain the allergen. Your immune system will eventually develop a tolerance to the allergen. Your provider will gradually increase the dosage over hours or even days until your body can accept the drug without reacting.
- #40 Drug allergy // Middlesex Healthhttps://middlesexhealth.org/learning-center/diseases-and-conditions/drug-allergy
A drug allergy is the reaction of the immune system to a medicine. […] The most common symptoms of drug allergy are hives, rash and fever. […] A drug allergy also may cause serious reactions. This includes a severe, life-threatening condition known as anaphylaxis. […] If you have milder symptoms of a drug allergy, see a healthcare professional as soon as possible. […] A drug allergy happens when the immune system mistakenly identifies a medicine as a harmful substance, such as a virus or bacterium. […] The next time you take the medicine, these specific antibodies flag the medicine and direct immune system attacks on the substance. […] If a healthcare professional determines that you have a drug allergy or likely allergy stopping the medicine is the first step in treatment. […] Anaphylaxis requires an immediate epinephrine shot. Hospital care also is needed to maintain blood pressure and support breathing.
- #41 Anaphylaxis: Recognition and Management | AAFPhttps://www.aafp.org/pubs/afp/issues/2020/0915/p355.html
Anaphylaxis is a life-threatening systemic reaction, normally occurring within one to two hours of exposure to an allergen. […] Coexisting asthma, mast cell disorders, older age, underlying cardiovascular disease, peanut and tree nut allergy, and drug-induced reactions are associated with severe or fatal anaphylactic reactions. […] Following an anaphylactic reaction, management should focus on developing an emergency action plan, referral to an allergist, and patient education on avoidance of triggers and appropriate use of an epinephrine auto-injector. […] The mainstay of treatment of acute IgE-mediated or nonimmune anaphylaxis is epinephrine. […] Delayed or lack of epinephrine use continues to be a problem despite current guidelines emphasizing the importance of early administration.
- #42 Anaphylaxis: Recognition and Management | AAFPhttps://www.aafp.org/pubs/afp/issues/2020/0915/p355.html
Antihistamines and corticosteroids are not effective first-line treatments for anaphylaxis. Guidelines recommend that antihistamines and corticosteroids be used only as an adjunct to epinephrine. […] All patients at risk of anaphylaxis should be provided with an action plan instructing them on how to manage an episode of anaphylaxis, including the proper administration of epinephrine. […] Referral to an allergist is appropriate if a clinician feels inadequately trained to provide education or if the patient presents after the reaction and the offending agent cannot be confirmed.
- #43 Anaphylaxis: Recognition and Management | AAFPhttps://www.aafp.org/pubs/afp/issues/2020/0915/p355.html
Antihistamines and corticosteroids are not effective first-line treatments for anaphylaxis. Guidelines recommend that antihistamines and corticosteroids be used only as an adjunct to epinephrine. […] All patients at risk of anaphylaxis should be provided with an action plan instructing them on how to manage an episode of anaphylaxis, including the proper administration of epinephrine. […] Referral to an allergist is appropriate if a clinician feels inadequately trained to provide education or if the patient presents after the reaction and the offending agent cannot be confirmed.
- #44 Anaphylactic Shock Nursing Care Management and Study Guide – Nurseslabshttps://nurseslabs.com/anaphylactic-shock/
Nursing interventions for the patient are: Monitor clients airway. Assess the client for the sensation of a narrowed airway. […] Monitor the oxygenation status. Monitor oxygen saturation and arterial blood gas values. […] Expected patient outcomes include: Client maintained an effective breathing pattern. […] Client and significant others verbalized understanding of allergic reaction, its prevention, and management. […] Upon discharge, the patient and family need to learn about the following: Emergency medications. The nurse should provide information about emergency medications and plans that should be considered should a crisis reoccur. […] The focus of documentation include: Assessment findings including respiratory rate, character of breath sounds; frequency, amount, and appearance of secretions; presence of cyanosis; laboratory findings; and mentation level.
- #45 Anaphylaxis: Nursing Diagnosis & Interventions | Nurse.comhttps://www.nurse.com/clinical-guides/anaphylaxis/?srsltid=AfmBOopnBF2OblV3oQPZ0A6sj25TQq7CY1X4O_PrHpvbOiVs3EKBCU2z
If an individual stops breathing or their heart stops beating during an anaphylactic attack, they require cardiopulmonary resuscitation (CPR). […] Because anaphylaxis is a medical emergency, it is essential first to assess and stabilize the individuals. […] If the individual is unstable, activate the emergency response system. […] Monitor vital signs, respiratory status, and signs and symptoms of complications. […] Educate the individual and/or caregiver regarding avoidance of allergens and how to use an EpiPen. […] The individual and/or caregivers will verbalize understanding of an allergic reaction, prevention, and management of anaphylaxis. […] Instruct caregivers about anaphylaxis, its diagnosis, and treatment. […] Always keep an epinephrine injector on hand. […] Discuss referral to an allergist.
- #46 Drug Allergy: Care Instructions | Kaiser Permanentehttps://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.drug-allergy-care-instructions.uf7209
Go to the emergency room every time you have a severe reaction. Go even if you have used your epinephrine medicine and are feeling better. Symptoms can come back after taking the medicine. […] Be sure that anyone treating you for any health problem knows that you are allergic to this medicine. […] Use an epinephrine medicine, such as an epinephrine shot or nasal spray, if you think you are having a severe allergic reaction. […] Call 911 anytime you think you may need emergency care. For example, call if you have symptoms of a severe allergic reaction. […] Watch closely for changes in your health, and be sure to contact your doctor if you do not get better as expected.
- #47https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=uf7209
Go to the emergency room every time you have a severe reaction. Go even if you have used your shot of epinephrine and are feeling better. Symptoms can come back after a shot. […] Be safe with medicines. If you were given a medicine for your allergic reaction, take it exactly as directed. Call your doctor or nurse advice line if you think you are having a problem with your medicine. […] Avoid medicines like the one that caused your allergy. Ask your doctor or pharmacist if you think you may be taking a similar medicine. […] Wear medical alert jewellery that lists your allergies. […] Be sure that anyone treating you for any health problem knows that you are allergic to this medicine. […] Give an epinephrine shot if you think you are having a severe allergic reaction. […] After giving an epinephrine shot, call 911, even if you feel better.
- #48 Anaphylactic Shock Nursing Care Management and Study Guide – Nurseslabshttps://nurseslabs.com/anaphylactic-shock/
Nursing interventions for the patient are: Monitor clients airway. Assess the client for the sensation of a narrowed airway. […] Monitor the oxygenation status. Monitor oxygen saturation and arterial blood gas values. […] Expected patient outcomes include: Client maintained an effective breathing pattern. […] Client and significant others verbalized understanding of allergic reaction, its prevention, and management. […] Upon discharge, the patient and family need to learn about the following: Emergency medications. The nurse should provide information about emergency medications and plans that should be considered should a crisis reoccur. […] The focus of documentation include: Assessment findings including respiratory rate, character of breath sounds; frequency, amount, and appearance of secretions; presence of cyanosis; laboratory findings; and mentation level.
- #49 Drug allergies: MedlinePlus Medical EncyclopediaLockhttps://medlineplus.gov/ency/article/000819.htm
Drug allergies are a group of symptoms caused by an allergic reaction to a drug (medicine). […] A drug allergy involves an immune response in the body that produces an allergic reaction to a medicine. […] Most drug allergies cause minor skin rashes and hives. These symptoms may occur right away or hours after receiving the drug. […] The goal of treatment is to relieve symptoms and prevent a severe reaction. […] Treatment may include: Antihistamines to relieve mild symptoms such as rash, hives, and itching. […] The offending medicine and similar drugs should be avoided. Make sure all your providers — including dentists and hospital staff — know about any drug allergies that you or your children have. […] Most drug allergies respond to treatment. But sometimes, they can lead to severe asthma, anaphylaxis, or death. […] Contact your provider if you are taking a medicine and seem to be having a reaction to it. […] There is generally no way to prevent a drug allergy. […] If you have a known drug allergy, avoiding the drug is the best way to prevent an allergic reaction.
- #50 Drug Allergies | Reactions, Symptoms & Treatment | ACAAI Public Websitehttps://acaai.org/allergies/allergic-conditions/drug-allergies/
If you develop a rash, hives or difficulty breathing after taking certain medications, you may have a drug allergy. […] People with drug allergies may experience symptoms regardless of whether their medicine comes in liquid, pill or injectable form. If you feel confused about your symptoms and which medications are safe for you to take then itâs time to take control and see an allergist. […] Seek immediate medical care if symptoms worsen or multiple symptoms occur together (anaphylaxis). […] Make sure that all of your health care providers, including your pharmacist, are aware of your allergy. If you have a history of anaphylaxis, wear a medical alert bracelet that lists your trigger. […] If you have a drug allergy: Make sure all of your doctors are aware of your allergy and the symptoms you experienced.
- #51 Drug Allergies | Reactions, Symptoms & Treatment | ACAAI Public Websitehttps://acaai.org/allergies/allergic-conditions/drug-allergies/
If there is no suitable alternative to the antibiotic that you are allergic to, you will need to undergo drug desensitization. […] Desensitization can help only if you are taking the drug every day. […] If you experience any of these more severe symptoms, immediately use your epinephrine auto-injector and call 911.
- #52 Drug Allergy: Causes, Symptoms, Diagnosis & Treatmenthttps://my.clevelandclinic.org/health/diseases/8621-medication-allergies
Drug allergies are an allergic reaction to medications. Its when your bodys immune system overreacts to medications. Your body develops a sensitivity to one of the substances in the medication and remembers it as a harmful foreign invader, like bacteria or viruses. The next time you ingest that drug, your immune system releases antibodies to remove it from your body. […] A drug allergy can be deadly. If you or a loved one have severe drug allergy symptoms, including swelling of your tongue or throat, trouble breathing, a fast heartbeat, lightheadedness or unconsciousness, you must act quickly: Call 911 or your local emergency number. Go to your nearest emergency room (ER) as soon as possible. […] Your healthcare provider may recommend the following drug allergy treatments: Stop taking the drug. Once the drug leaves your body, your symptoms should start to fade. If youre taking the medication to treat a condition, your provider will prescribe another medicine that doesnt cause an allergic reaction. Antihistamines. Antihistamines block the effects of histamine in your body. Corticosteroids. Corticosteroids are anti-inflammatory drugs that help reduce the production of chemicals that cause inflammation. Bronchodilators. Bronchodilators are a type of medication that help relieve symptoms that affect your lungs. Epinephrine auto-injector (EpiPen). If you have severe medication allergies, your provider may prescribe this device. Epinephrine quickly reverses the symptoms of anaphylaxis. Your provider will explain when and how to use it. Allergy desensitization. During allergy desensitization, a provider gives you small amounts of medications that contain the allergen. Your immune system will eventually develop a tolerance to the allergen. Your provider will gradually increase the dosage over hours or even days until your body can accept the drug without reacting.
- #53 Drug Allergies | Reactions, Symptoms & Treatment | ACAAI Public Websitehttps://acaai.org/allergies/allergic-conditions/drug-allergies/
If there is no suitable alternative to the antibiotic that you are allergic to, you will need to undergo drug desensitization. […] Desensitization can help only if you are taking the drug every day. […] If you experience any of these more severe symptoms, immediately use your epinephrine auto-injector and call 911.
- #54https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=bz1117
A drug allergy occurs when the immune system overreacts to something in a medicine. This causes an allergic reaction. Your child may have: […] A reaction can range from mild to deadly. […] Follow-up care is a key part of your child’s treatment and safety. Be sure to make and go to all appointments, and call your doctor or nurse advice line if your child is having problems. […] Know the signs of a severe allergic reaction (called anaphylaxis). […] Your doctor may prescribe a shot of epinephrine (sometimes called an Epi-pen) to carry in case your child has a severe reaction. […] Go to the emergency room every time your child has a severe reaction. […] If your child was given a medicine for an allergic reaction, give it exactly as directed. […] Avoid giving your child medicines like the one that caused the allergy.
- #55https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=bz1117
Have your child wear medical alert jewellery that lists their allergies and anaphylaxis reaction. […] Be sure that anyone treating your child for any health problem knows that your child is allergic to this medicine. […] Give an epinephrine shot if: […] After giving an epinephrine shot, call 911 even if your child feels better. […] Call your doctor or nurse advice line now or seek immediate medical care if: […] Watch closely for changes in your child’s health, and be sure to contact your doctor or nurse advice line if:
- #56 Effective Management of Severe Drug Allergy Rasheshttps://www.beckerentandallergy.com/blog/managing-severe-drug-allergy-rashes
Managing severe allergies in children often requires the regular use of preventive medication, especially for those who are at risk of anaphylactic reactions. […] Cross-reactivity, a term used in the context of adverse drug reactions, explains a situation where someone allergic to one medication might also have an allergic reaction to another, different drug. […] Clear communication with healthcare providers is important for managing a medical condition such as a drug allergy rash. […] Understanding medication labels is essential for managing severe cases of drug allergy rash.
- #57 Drug Allergies | Reactions, Symptoms & Treatment | ACAAI Public Websitehttps://acaai.org/allergies/allergic-conditions/drug-allergies/
If you develop a rash, hives or difficulty breathing after taking certain medications, you may have a drug allergy. […] People with drug allergies may experience symptoms regardless of whether their medicine comes in liquid, pill or injectable form. If you feel confused about your symptoms and which medications are safe for you to take then itâs time to take control and see an allergist. […] Seek immediate medical care if symptoms worsen or multiple symptoms occur together (anaphylaxis). […] Make sure that all of your health care providers, including your pharmacist, are aware of your allergy. If you have a history of anaphylaxis, wear a medical alert bracelet that lists your trigger. […] If you have a drug allergy: Make sure all of your doctors are aware of your allergy and the symptoms you experienced.
- #58 Drug Allergy | Allergy UK | National Charityhttps://www.allergyuk.org/types-of-allergies/drug-allergy/
Drug allergy signs and symptoms may include: Rashes, Itching, Nausea, Vomiting, Diarrhoea (or occasionally constipation), Lethargy, Headaches, Blurred vision. […] Anaphylaxis is a rare, life-threatening reaction to a drug allergy that causes the widespread dysfunction of body systems. Signs and symptoms of anaphylaxis include: Tightening of the airways and throat, causing trouble breathing, Nausea or abdominal cramps, Vomiting or diarrhea, Dizziness or lightheadedness, Weak, rapid pulse, Drop in blood pressure, Seizure, Loss of consciousness. […] If you are allergic to a drug, it is important to make sure everyone knows. Health services are sometimes not very good at communicating this information or sharing it with other services or even looking at it when it is recorded. Here are 5 top tips to help you: Always ask whether the allergy has been recorded in your notes. Volunteer the information to everyone who is involved in your care, even if they donât ask. Make sure you are given an allergy bracelet when you are in hospital. If your allergy is severe, consider wearing your own allergy bracelet. If you are given drugs to take at home, always read the label and information leaflet very carefully.
- #59 I gave an IV medication that the patient is allergic to – Patient Medicationshttps://allnurses.com/i-gave-iv-medication-patient-t687599/
I gave a patient a medication she is allergic to. […] I told her to monitor the patient for the first signs of allergic reaction. […] I will be making an incident report about this, I am worried about the patient and hoping she will be alright. […] If a patient lists something as an allergy, it’s your responsibility to not give that med, even if 90% OF THE TIME IT ISN’T A TRUE ALLERGY BUT MORESO A SYMPTOM OR ADVERSE EFFECT THAT MADE THE PATIENT SIMPLY UNCOMFORTABLE. […] Nurses make mistakes, we are human. You’ll learn from it and likely not do it again. […] You do a disservice to your patient and to other nurses when you aren’t forthcoming in your med errors.
- #60 Penicillin Allergy – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/penicillin-allergy.htm
Penicillin allergy is often overreported, with the majority of patients who report penicillin allergy able to tolerate the medication. […] Patients often are incorrectly labeled as allergic to penicillin and are therefore denied the benefit of a -lactam therapy. The presence of a penicillin allergy label considerably reduces prescribing options for affected patients. […] For persons who have a positive skin test reactive to penicillin (either to the major or minor determinants), treatment with a -lactam antibiotic is not usually advised, and other effective antimicrobials should be used. […] Desensitization is required for persons who have a documented penicillin allergy and for whom no therapeutic alternatives exist (e.g., syphilis during pregnancy and persons with neurosyphilis). […] Patients who have a positive skin test should not receive -lactam drugs in the ambulatory setting and should be referred to an allergist or penicillin allergy expert for further evaluation.
- #61 Penicillin Allergy – STI Treatment Guidelineshttps://www.cdc.gov/std/treatment-guidelines/penicillin-allergy.htm
Penicillin allergy is often overreported, with the majority of patients who report penicillin allergy able to tolerate the medication. […] Patients often are incorrectly labeled as allergic to penicillin and are therefore denied the benefit of a -lactam therapy. The presence of a penicillin allergy label considerably reduces prescribing options for affected patients. […] For persons who have a positive skin test reactive to penicillin (either to the major or minor determinants), treatment with a -lactam antibiotic is not usually advised, and other effective antimicrobials should be used. […] Desensitization is required for persons who have a documented penicillin allergy and for whom no therapeutic alternatives exist (e.g., syphilis during pregnancy and persons with neurosyphilis). […] Patients who have a positive skin test should not receive -lactam drugs in the ambulatory setting and should be referred to an allergist or penicillin allergy expert for further evaluation.
- #62 How to handle certain patient „allergies” – New Nurses, First Yearhttps://allnurses.com/how-handle-certain-patient-quot-t499662/
I know some facilities have taken to differentiating intolerable adverse effect vs. allergic reaction. […] On our EMR, we list anything that the pt claims to have as an „allergy.” There is then a spot for their reaction (anaphylaxis, hives, nausea, etc.)–even if it does not qualify as a true allergy.
- #63 Effective Management of Severe Drug Allergy Rasheshttps://www.beckerentandallergy.com/blog/managing-severe-drug-allergy-rashes
Managing severe allergies in children often requires the regular use of preventive medication, especially for those who are at risk of anaphylactic reactions. […] Cross-reactivity, a term used in the context of adverse drug reactions, explains a situation where someone allergic to one medication might also have an allergic reaction to another, different drug. […] Clear communication with healthcare providers is important for managing a medical condition such as a drug allergy rash. […] Understanding medication labels is essential for managing severe cases of drug allergy rash.
- #64 Drug allergy | Allergy, Asthma & Clinical Immunology | Full Texthttps://aacijournal.biomedcentral.com/articles/10.1186/s13223-018-0289-y
The mainstay of treatment for drug allergy is avoidance of the offending drug. When available, alternative medications with unrelated chemical structures should be substituted. Cross-reactivity among drugs should be taken into consideration when choosing alternative medications. If a particular drug to which the patient is allergic is indicated and there is no suitable alternative, induction of drug tolerance procedures may be considered to induce temporary tolerance to the drug.
- #65 Effective Management of Severe Drug Allergy Rasheshttps://www.beckerentandallergy.com/blog/managing-severe-drug-allergy-rashes
Managing severe allergies in children often requires the regular use of preventive medication, especially for those who are at risk of anaphylactic reactions. […] Cross-reactivity, a term used in the context of adverse drug reactions, explains a situation where someone allergic to one medication might also have an allergic reaction to another, different drug. […] Clear communication with healthcare providers is important for managing a medical condition such as a drug allergy rash. […] Understanding medication labels is essential for managing severe cases of drug allergy rash.
- #66 Providing information and support to patients – Drug Allergy – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK274145/
The group agreed that a dialogue between the healthcare professional and the patient who has had a suspected or confirmed allergic reaction, or their carer, is important to ensure that opportunities are given to ask questions and to provide reassurance as well as practical advice. […] Recommendations on checking to ensure that patients have the necessary knowledge, and on giving patients the responsibility to carry and share their drug allergy information are intended to minimise patients’ fear, enhance communication between patients, clinicians and pharmacists, and enable the patient to better manage their confirmed or suspected drug allergy.
- #67 Providing information and support to patients – Drug Allergy – NCBI Bookshelfhttps://www.ncbi.nlm.nih.gov/books/NBK274145/
The group agreed that a dialogue between the healthcare professional and the patient who has had a suspected or confirmed allergic reaction, or their carer, is important to ensure that opportunities are given to ask questions and to provide reassurance as well as practical advice. […] Recommendations on checking to ensure that patients have the necessary knowledge, and on giving patients the responsibility to carry and share their drug allergy information are intended to minimise patients’ fear, enhance communication between patients, clinicians and pharmacists, and enable the patient to better manage their confirmed or suspected drug allergy.
- #68 Anaphylactic Shock Nursing Care Management and Study Guide – Nurseslabshttps://nurseslabs.com/anaphylactic-shock/
The nurse has an important role in preventing anaphylactic shock. […] The nurse must assess all patients for allergies or previous reactions to antigens. […] The nurse must also assess the patients understanding of previous reactions and steps taken by the patient and the family to prevent further exposure to antigens. […] When new allergies are identified, the nurse advises the patient to wear or carry identification that names the specific allergen or antigen. […] Based on the assessment data, the nursing diagnoses appropriate for the patient are: Impaired gas exchange related to ventilation perfusion imbalance. […] The major goals for a patient with anaphylactic shock are: Client will maintain an effective breathing pattern, as evidenced by relaxed breathing at normal rate and depth and absence of adventitious breath sounds.
- #69 Anaphylactic Shock Nursing Care Management and Study Guide – Nurseslabshttps://nurseslabs.com/anaphylactic-shock/
Nursing interventions for the patient are: Monitor clients airway. Assess the client for the sensation of a narrowed airway. […] Monitor the oxygenation status. Monitor oxygen saturation and arterial blood gas values. […] Expected patient outcomes include: Client maintained an effective breathing pattern. […] Client and significant others verbalized understanding of allergic reaction, its prevention, and management. […] Upon discharge, the patient and family need to learn about the following: Emergency medications. The nurse should provide information about emergency medications and plans that should be considered should a crisis reoccur. […] The focus of documentation include: Assessment findings including respiratory rate, character of breath sounds; frequency, amount, and appearance of secretions; presence of cyanosis; laboratory findings; and mentation level.
- #70 Anaphylaxis: Nursing Diagnosis & Interventions | Nurse.comhttps://www.nurse.com/clinical-guides/anaphylaxis/?srsltid=AfmBOopnBF2OblV3oQPZ0A6sj25TQq7CY1X4O_PrHpvbOiVs3EKBCU2z
If an individual stops breathing or their heart stops beating during an anaphylactic attack, they require cardiopulmonary resuscitation (CPR). […] Because anaphylaxis is a medical emergency, it is essential first to assess and stabilize the individuals. […] If the individual is unstable, activate the emergency response system. […] Monitor vital signs, respiratory status, and signs and symptoms of complications. […] Educate the individual and/or caregiver regarding avoidance of allergens and how to use an EpiPen. […] The individual and/or caregivers will verbalize understanding of an allergic reaction, prevention, and management of anaphylaxis. […] Instruct caregivers about anaphylaxis, its diagnosis, and treatment. […] Always keep an epinephrine injector on hand. […] Discuss referral to an allergist.
- #71 Drug Allergies | Reactions, Symptoms & Treatment | ACAAI Public Websitehttps://acaai.org/allergies/allergic-conditions/drug-allergies/
If you develop a rash, hives or difficulty breathing after taking certain medications, you may have a drug allergy. […] People with drug allergies may experience symptoms regardless of whether their medicine comes in liquid, pill or injectable form. If you feel confused about your symptoms and which medications are safe for you to take then itâs time to take control and see an allergist. […] Seek immediate medical care if symptoms worsen or multiple symptoms occur together (anaphylaxis). […] Make sure that all of your health care providers, including your pharmacist, are aware of your allergy. If you have a history of anaphylaxis, wear a medical alert bracelet that lists your trigger. […] If you have a drug allergy: Make sure all of your doctors are aware of your allergy and the symptoms you experienced.
- #72 Drug Allergies | Reactions, Symptoms & Treatment | ACAAI Public Websitehttps://acaai.org/allergies/allergic-conditions/drug-allergies/
If you develop a rash, hives or difficulty breathing after taking certain medications, you may have a drug allergy. […] People with drug allergies may experience symptoms regardless of whether their medicine comes in liquid, pill or injectable form. If you feel confused about your symptoms and which medications are safe for you to take then itâs time to take control and see an allergist. […] Seek immediate medical care if symptoms worsen or multiple symptoms occur together (anaphylaxis). […] Make sure that all of your health care providers, including your pharmacist, are aware of your allergy. If you have a history of anaphylaxis, wear a medical alert bracelet that lists your trigger. […] If you have a drug allergy: Make sure all of your doctors are aware of your allergy and the symptoms you experienced.
- #73 Acute Hypersensitivity Reactions: What Nurses Need to Know – Johns Hopkins School of Nursinghttps://nursing.jhu.edu/magazine/articles/2011/04/acute-hypersensitivity-reactions-what-nurses-need-to-know/
An acute hypersensitivity reaction is a rare but serious complication of exposure to foods, natural-rubber latex, medications, and other antigens. […] Nurses and nurse practitioners must recognize HSR risk factors, read early signs and symptoms, and intervene to protect the patient from further harm. […] Oncology nurses are particularly likely to witness HSRs from antimicrobials, biological and chemotherapeutic agents. […] All chemotherapy has the potential to cause an HSR. […] If you suspect your patient is experiencing early symptoms of an acute HSR, don’t hesitate to implement your emergency interventions. […] STOP the infusion but maintain IV access. […] CALL the provider. […] ASSESS your patient further: collect vital signs, use a pulse oximeter to obtain oxygen saturation, listen to breath sounds, and check for symptom progression.
- #74 Acute Hypersensitivity Reactions: What Nurses Need to Know – Johns Hopkins School of Nursinghttps://nursing.jhu.edu/magazine/articles/2011/04/acute-hypersensitivity-reactions-what-nurses-need-to-know/
Finally, PREPARE for emergency treatment, including the potential need to administer IV fluids, oxygen, and resuscitative medications. […] An acute HSR is a frightening experience. […] After the initial event, supportive care and close monitoring will be needed for several hours to ensure that symptoms do not recur. […] Recognizing high-risk patients and situations is an essential first step in reducing HSR morbidity and mortality. […] Clinical variables known to increase risk for HSRs include personal history of drug allergy, multiple allergy syndrome, presence of Epstein-Barr or HIV infection, or concurrent asthma. […] For high-risk medications, premedications with antihistamines and corticosteroids are widely used. […] An acute HSR is also an adverse drug reaction (ADR) and should be reported according to your organization’s policies. […] Enhanced reporting of ADRs will assist in defining true incidences of drug reactions. […] Readily available emergency supplies and medications can minimize the adverse outcomes of severe HSRs.
- #75 A Nurseâs Guide to Treating Anaphylaxishttps://nursingcecentral.com/anaphylaxis/
Anaphylaxis is a rapid, life-threatening allergic reaction caused by a type I IgE-mediated hypersensitivity reaction, affecting 20,000-50,000 people in the US annually. […] Recognizing the signs and symptoms, understanding the causes, and administering prompt treatment are crucial to managing this life-threatening condition. […] Symptoms usually begin within 5 to 30 minutes. Moreover, ask the patients family members about a family history of drug allergies or previous reactions. […] The nursing processes for anaphylaxis are: […] The most important responsibility is to ensure the adequacy of the airway, breathing, and circulation for the patient. […] If the patient got an anaphylaxis reaction, you need to give the following information to the patient and his caregivers: […] Nurses play a vital role in recognizing symptoms, administering appropriate treatment, and educating patients and their families on prevention and management strategies.
- #76 Drug allergies: MedlinePlus Medical EncyclopediaLockhttps://medlineplus.gov/ency/article/000819.htm
Drug allergies are a group of symptoms caused by an allergic reaction to a drug (medicine). […] A drug allergy involves an immune response in the body that produces an allergic reaction to a medicine. […] Most drug allergies cause minor skin rashes and hives. These symptoms may occur right away or hours after receiving the drug. […] The goal of treatment is to relieve symptoms and prevent a severe reaction. […] Treatment may include: Antihistamines to relieve mild symptoms such as rash, hives, and itching. […] The offending medicine and similar drugs should be avoided. Make sure all your providers — including dentists and hospital staff — know about any drug allergies that you or your children have. […] Most drug allergies respond to treatment. But sometimes, they can lead to severe asthma, anaphylaxis, or death. […] Contact your provider if you are taking a medicine and seem to be having a reaction to it. […] There is generally no way to prevent a drug allergy. […] If you have a known drug allergy, avoiding the drug is the best way to prevent an allergic reaction.