Materiały źródłowe

• #1 Trichinosis – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/trichinosis/symptoms-causes/syc-20378583

  Signs and symptoms of trichinosis infection and how severe the infection is can vary. This depends on the number of larvae eaten in the infected meat. […] Mild cases of trichinosis those with only a small number of parasites in your body may cause no signs or symptoms. Symptoms can develop with moderate or heavy infestation a large number of parasites in your body. These symptoms sometimes get worse as the roundworm (trichinella) larvae travel through your body. […] Digestive symptoms can begin 1 to 2 days after infection. At this stage, you may experience: Diarrhea, Stomach (abdominal) pain, Severe tiredness and weakness (fatigue), Nausea and vomiting. […] Symptoms caused by muscle tissue invasion usually start 2 to 8 weeks after infection and include: High fever and chills, Muscle pain and tenderness, Aching joints, Swelling of the eyelids or face, Weakness, Headache, Sensitivity to light, Pink eye (conjunctivitis), Itchy, irritated skin.

• #2 Trichinosis: Causes, Symptoms, Treatment & Prevention

  https://my.clevelandclinic.org/health/diseases/7142-trichinosis

  Symptoms of trichinosis range from very mild to severe. Early symptoms, which start a few days after the worms enter your body, may include: Nausea and vomiting. Diarrhea. Pain in your abdomen. […] Later symptoms may begin about two weeks after you eat the infected meat and may last as long as several weeks. They include: Muscle soreness. Fever. Headaches. Eye swelling. Chills. Extreme tiredness. Diarrhea or constipation. Cough. Rash or itchy skin. […] In severe cases, trichinosis can cause: Difficulty with coordination and movement. Inflammation of your heart muscles. Difficulty breathing. Inflammation in your brain (encephalitis). […] These symptoms can last from five to 45 days, but they usually begin to appear 10 to 14 days after consuming the infected meat. Abdominal symptoms can occur much sooner at one to two days after infection. Milder cases of trichinosis are often mistaken for the flu or other common illnesses. In extreme cases, trichinosis may result in death.

• #3 Symptoms of Trichinellosis | Trichinellosis (Trichinosis) | CDC

  https://www.cdc.gov/trichinellosis/symptoms/index.html

  Trichinellosis symptoms are often mild and mistaken for flu. […] Severe trichinellosis can cause fever and chills, facial swelling, joint and muscle aches, and rash. […] Some people with trichinellosis experience no symptoms. Infections with mild symptoms may go undiagnosed as people often think they have the flu or some other common illness. In mild to moderate cases, most symptoms go away within a few months without treatment. […] Symptoms can range from very mild to severe. How severe symptoms become may have something to do with how many Trichinella larvae (young worms) a person ate in contaminated meat. […] If the infection is heavy, you may have trouble coordinating movements and have heart and breathing problems. Although it’s rare, severe cases can end in death.

• #4 Trichinosis – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/nematodes-roundworms/trichinosis

  Symptoms include initial gastrointestinal irritation followed by periorbital edema, muscle pain, fever, and eosinophilia. […] One to 2 weeks after infection, systemic symptoms and signs begin: facial or periorbital edema, myalgia, persistent fever, headache, and subconjunctival hemorrhages and petechiae. Eye pain and photophobia often precede myalgia. […] Symptoms due to muscle invasion may mimic symptoms of polymyositis. The muscles of respiration, speech, mastication, and swallowing may be painful. Severe dyspnea may occur in heavy infections. […] Fever is generally remittent, rising to 39 C or higher, remaining elevated for several days, and then falling gradually. […] Eosinophilia usually begins when newborn larvae invade tissues, peaks 2 to 4 weeks after infection, and gradually declines as the larvae encyst.

• #5 Trichinosis | Health & Human Services

  https://hhs.iowa.gov/center-acute-disease-epidemiology/epi-manual/information-other-diseases-and-conditions-fact-sheets/trichinosis

  Trichinosis in humans can range from asymptomatic to fatal, depending on the infective dose. In the week following ingestion of infected meat, a patient may experience nausea, vomiting, diarrhea and abdominal discomfort, as the released larvae mature and attach to the intestinal mucosa. A sudden onset of muscle soreness and pain, fever, edema of the upper eyelid and urticarial rash, 2 – 8 weeks after ingestion, is characteristic of earlier infection, as larvae migrate into muscle tissue. […] Eye pain, photophobia, thirst, profuse sweating, chills, weakness and a rapid increase in eosinophil counts on blood exam may also occur. Recurring fever up to 104F usually stops after 1 – 6 weeks. In the most severe infections, cardiac and neurologic complications, sometimes leading to death, may occur in the 3rd – 6th week. […] Gastrointestinal symptoms may appear within a few days after infection; appearance of systemic symptoms ranges from 5 – 45 days. The usual incubation period is 8 – 15 days. If large numbers of cysts are ingested, symptoms may occur more rapidly.

• #6 Trichinellosis – Symptoms, diagnosis and treatment | BMJ Best Practice

  https://bestpractice.bmj.com/topics/en-us/1140

  Trichinellosis is a parasitosis caused by ingestion of under-cooked meat containing Trichinella species larvae. […] Bi-phasic disease characterised by a gastrointestinal (enteric) phase followed by a systemic (parenteral) phase. […] The intestinal phase occurs within a few days of ingestion of the parasite and manifests with gastrointestinal symptoms, such as abdominal pain, nausea, vomiting, and diarrhoea. […] The systemic phase most commonly manifests with fever, eosinophilic myositis, myalgia, and peri-orbital oedema, although it may also cause myocarditis and encephalitis. […] Disease severity can range from asymptomatic infection to fatal disease. However, a full recovery within 6 weeks to 6 months is the most common course. […] Trichinellosis is a parasitosis caused by the ingestion of raw or under-cooked meat (usually pork) containing Trichinella species cysts. It is a bi-phasic disease characterised by a gastrointestinal (enteric) phase followed by a systemic (parenteral) phase. The intestinal phase occurs within a few days of ingesting the parasite and manifests with gastrointestinal symptoms, such as abdominal pain, nausea, vomiting, and diarrhoea. After the first week, larvae released from the cysts become adult worms and mate. The female parasites then release newborn larvae that disseminate, leading to the systemic phase. This phase manifests with fever, eosinophilic myositis, myalgia, and peri-orbital oedema. Rarely, it may also cause myocarditis or encephalitis.

• #7 Trichinosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536945/

  Trichinosis or trichinellosis is a helminth infection primarily transmitted via the ingestion of improperly prepared food. […] It can be potentially fatal, but more commonly is a self-limiting disease. […] Symptoms of Trichinella depend on the current stage of infection. During the enteral (intestinal) phase, the initial symptoms are mild transient diarrhea and nausea (from the intestinal invasion of the larvae), vomiting, upper abdominal pain, low-grade fever, and malaise. These begin 1-2 days after ingestion of infected meat. From 2-6 weeks after ingestion, intestinal symptoms disappear, and symptoms from the parenteral stage (skeletal muscle) appear. They include but are not limited to periorbital or facial edema, diffuse myalgia, and a paralysis-like state. The severity of disease is in correlation with the number of larvae ingested.

• #8 Trichinellosis – Symptoms, Causes, Images, and Treatment Options

  https://www.epocrates.com/online/diseases/1140/trichinellosis

  Trichinellosis is a parasitosis caused by ingestion of undercooked meat containing Trichinella species larvae. […] The intestinal phase occurs within a few days of ingestion of the parasite and manifests with gastrointestinal symptoms, such as abdominal pain, nausea, vomiting, and diarrhea. […] The systemic phase most commonly manifests with fever, eosinophilic myositis, myalgia, and periorbital edema, although it may also cause myocarditis and encephalitis.

• #9 Trichinosis Fact Sheet

  https://www.health.ny.gov/diseases/communicable/trichinosis/fact_sheet.htm

  Stomach symptoms tend to appear 1-2 days after eating infected meat. These symptoms usually include diarrhea (loose stool/poop), nausea (feeling of sickness in the stomach), fatigue, and stomach pain. Other symptoms may appear 2-8 weeks after infection and may include fever, headaches, chills, muscle soreness, pain and swelling around the eyes. The length and severity of symptoms varies depending upon the number of parasites in the meat and the amount eaten. Although rare, complications can develop and affect the heart, brain, and lungs; these complications may be fatal. […] Trichinosis is diagnosed when an individual has the symptoms, has a positive blood test for the parasite Trichinella, and has eaten raw or undercooked pork or wild game meat. Occasionally trichinosis is diagnosed by examining small pieces of the patient’s muscle under the microscope.

• #10 Trichinellosis (Trichinosis) – Epidemiology

  https://www.vdh.virginia.gov/epidemiology/epidemiology-fact-sheets/trichinellosis-trichinosis/

  Abdominal discomfort, nausea, vomiting and diarrhea, fatigue, and fever are often the first symptoms of trichinellosis. […] Aching joints, muscle pain, together with swelling of the face and eyes, sweating, chills, headaches, cough, itchy skin, and sometimes constipation occur later. […] The severity of the disease can be mild or very serious and depends on how much of the parasite is eaten in the contaminated food. Nervous system, heart and breathing problems can occur in cases of severe infection. For mild to moderate infections, most symptoms subside within a few months. Fatigue, weakness, muscle pain and diarrhea can last for months. […] Symptoms usually develop 8-15 days after eating the infected meat, with a range of 5-45 days. Gastrointestinal symptoms (abdominal pain, nausea, vomiting and diarrhea) may occur before the fever, sore muscles and other symptoms, sometimes as soon as 1-2 days after infection.

• #11 Trichinellosis (Trichinosis) | Texas DSHS

  https://www.dshs.texas.gov/notifiable-conditions/zoonosis-control/zoonosis-control-diseases-and-conditions/trichinellosis-trichinosis

  Trichinosis is a common infection worldwide. A person can get trichinellosis (trichinosis) after eating improperly cooked meat infected with the worm Trichinella spiralis. When a person eats meat from an infected animal, trichinella cysts hatch in the intestines and grow into adult roundworms. The roundworms then produce offspring that migrate through the lining of the intestines and into the bloodstream. These parasites invade muscle tissues, including the heart and diaphragm. […] Many people with trichinosis have no symptoms at all. Persons who show symptoms usually have nausea, diarrhea, vomiting, fever, and abdominal discomfort. Headache, fever, chills, cough, swelling of the upper eyelids, aching joints and muscle pain, itchy skin, diarrhea, or constipation may occur after the first symptoms. If the infection is heavy, patients may have problems coordinating movements and have heart and breathing problems.

• #12 Trichinosis: Causes, Symptoms, and Treatment

  https://www.webmd.com/food-recipes/food-poisoning/what-to-know-about-trichinosis-trichinellosis

  Trichinosis symptoms vary depending on the number of larvae consumed. […] At this first stage, some of your symptoms may include: Diarrhea, Vomiting, Fatigue, Fever, Nausea, Abdominal discomfort. […] At this stage, symptoms include: Fever, Chills, Swelling of your eyes and face, Itchy skin, Aching joints and muscle pains, Diarrhea, Constipation, Headache, Cough. […] If your infection is severe, you may have: Difficulty with coordination of your movements, Breathing problems, Heart problems, Death. […] In most cases, trichinosis will go away on its own. This may take a few months. But some symptoms like fatigue, diarrhea, and mild pain may linger for months or even years.

• #13 Trichinellosis – Helminthiases – Parasitic Diseases – Infectious Diseases – Diseases – McMaster Textbook of Internal Medicine

  https://empendium.com/mcmtextbook/chapter/B31.II.18.69.3.

  Trichinellosis (trichinosis) is a systemic inflammatory parasitic zoonosis that involves the skeletal muscles and causes allergic vasculitis. […] Depending on severity, invasion may be asymptomatic, subclinical, or associated with mild, moderate, or severe symptoms, including: […] 1) Acute diarrhea, which occurs in the early stage of invasion, when the adult forms of T spiralis invade the small intestine. Diarrhea is accompanied by anorexia, upper abdominal pain, and vomiting, which on average persist for 1 to 2 days. […] 2) Typical symptoms of trichinellosis, which are caused by penetration of larvae to muscle cells and a severe local inflammatory reaction: […] a) High-grade fever (often 40 degrees Celsius), myalgia (predominantly of the extraocular muscles, muscles of the neck, and flexor muscles of the extremities), malaise.

• #13 Trichinellosis – Helminthiases – Parasitic Diseases – Infectious Diseases – Diseases – McMaster Textbook of Internal Medicine

  https://empendium.com/mcmtextbook/chapter/B31.II.18.69.3.

  b) Signs and symptoms of parasitic tissue damage: Periorbital or (rarely) facial edema, petechiae in the conjunctiva and nail beds (in severe cases similar hemorrhages are also found in the brain, lungs, pericardium, and endocardium). A variety of concomitant cutaneous lesions may be observed. […] c) Involvement of other organs (in more severe invasions): see Complications, below. […] Signs and symptoms persist for 3 to 4 weeks (in heavy invasions even for 2-3 months), then slowly resolve, usually without sequelae. Fatigue, asthenia, and diarrhea may persist for a few months. […] In patients with severe trichinellosis (massive invasion) death can occur as a result of myocarditis, heart failure, meningitis, or encephalitis. In milder cases the prognosis is good and usually associated with a complete resolution of signs and symptoms.

• #14 :: Parasites, Hosts and Diseases

  https://www.parahostdis.org/m/journal/view.php?number=2527

  On her admission, patient was febrile with a mild erythema on her both cheeks, a maculopapular rash on her back, myalgias and livedo reticularis of lower extremities. […] Taking into consideration that the patients symptoms were persistent myalgias, arthralgias, recurrent rash and the main laboratory findings were the elevated inflammatory markers, the deferential diagnosis was restricted to the spectrum of autoimmune inflammatory diseases like systematic lupus erythematosus, rheumatoid arthritis or myositis. […] In the first stage, woman experienced fever and diarrhea (intestinal stage) and in the second stage, she suffered from myalgias (the muscle stage) with the appearance of a rash, a rare manifestation of trichinosis. These stages experienced form the patient in periods which are in an absolute accordance to life cycle stages of the parasite.

• #15 Trichinella spiralis Infection – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK538511/

  Trichinellosis, also called trichinosis, is a parasitic infection caused by roundworms (nematodes) from the genus Trichinella. Symptoms are diverse and may include generalized fever, abdominal pain, diarrhea, nausea, vomiting, or myalgias. The presentation can also include myocarditis and encephalitis. […] Symptoms include abdominal pain, diarrhea, nausea, and vomiting. Muscle pain is a common complaint, chiefly in the mid-abdomen, face (masseter), and chest (intercostal muscles). In some cases, the pain can be so severe, that the individual is disabled and may not be able to perform activities of daily living. […] Classic trichinellosis symptoms usually occur in 2 weeks after consumption of raw or undercooked meat and can last up to 8 weeks. Symptoms include fevers, chills, myalgias, periorbital or facial edema, weakness, and fatigue. […] Severe complications include myocarditis, life-threatening arrhythmias, meningitis, encephalitis, respiratory myositis, secondary bacterial pneumonia, hematuria, and renal failure.

• #16 Trichinosis – Infections – Merck Manual Consumer Version

  https://www.merckmanuals.com/home/infections/parasitic-infections-roundworms-nematodes/trichinosis

  At first, people may have nausea, diarrhea, and abdominal cramps, followed later by muscle pain, weakness, fever, headache, and sometimes inflammation of other organs. […] Once the larvae penetrate the muscles, people may develop other symptoms such as muscle pain and tenderness, weakness, high fever, headache, and swelling of the face, particularly around the eyes. The pain is often most pronounced in the muscles used to breathe, speak, chew, and swallow. In some people, the whites of the eyes become red, and their eyes hurt and become sensitive to bright light. These symptoms start approximately 1 to 2 weeks after infection. […] If many larvae are present, the heart, brain, and lungs may become inflamed. Heart failure, abnormal heart rhythms, seizures, and severe breathing problems may result. Death can occur but is rare. […] Without treatment, most trichinosis symptoms disappear by the third month of infection. Vague muscle pains and fatigue can last for many months.

• #17 Trichinosis – Wikipedia

  https://en.wikipedia.org/wiki/Trichinosis

  Initially: diarrhea, abdominal pain, vomiting. […] Later: swelling of the face, inflammation of the whites of the eyes, fever, muscle pains, rash. […] Migration of larvae to muscle, which occurs about a week after being infected, can cause swelling of the face, inflammation of the whites of the eyes, fever, muscle pains, and a rash. […] Minor infection may be without symptoms. […] Complications may include inflammation of heart muscle, central nervous system involvement, and inflammation of the lungs. […] The severity of symptoms caused by larval migration from the intestines depends on the number of larvae produced. […] As the larvae migrate through tissue and vessels, the body’s inflammatory response results in edema, muscle pain, fever, and weakness. […] A classic sign of trichinosis is periorbital edema, swelling around the eyes, which may be caused by vasculitis. […] Trichinosis can be fatal depending on the severity of the infection; death can occur 4–6 weeks after the infection, and is usually caused by myocarditis, encephalitis, or pneumonia.

• #18 Trichinosis – Symptoms & causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/trichinosis/symptoms-causes/syc-20378583

  With a large number of parasites, muscle pain and weakness can be severe. This can limit moving, breathing and speaking. […] Symptoms last for several months. But symptoms generally lessen when the larvae form cysts. Even after the infection is gone, fatigue, mild pain, weakness and diarrhea may last for months or years.

• #19 Trichinosis | UM Health-Sparrow

  https://www.uofmhealthsparrow.org/departments-conditions/conditions/trichinosis

  With a large number of parasites, muscle pain and weakness can be severe. This can limit moving, breathing and speaking. […] Symptoms last for several months. But symptoms generally lessen when the larvae form cysts. Even after the infection is gone, fatigue, mild pain, weakness and diarrhea may last for months or years. […] In cases with a large number of roundworm (trichinella) larvae, larvae can move through the body to muscle tissue in and around organs. This can cause potentially dangerous, even fatal, complications, such as pain and swelling (inflammation) of the: Muscle layer of the heart wall (myocarditis), Brain (encephalitis), Protective tissue layer surrounding the brain and spinal cord (meningitis), Lungs (pneumonitis). […] In cases with a mild or moderate number of larvae, most signs and symptoms typically go away within a few months. However, fatigue, mild pain, weakness and diarrhea may stay for many months or years. Infection with a large number of larvae can cause more-severe symptoms that need treatment right away.

• #20 Trichinosis: Causes, Symptoms, Treatment & Prevention

  https://my.clevelandclinic.org/health/diseases/7142-trichinosis

  Complications of untreated trichinosis can be serious. They might include inflammation and damage to your: Heart, which could result in irregular heart rhythm (arrhythmia) and/or heart failure. Brain, which could result in seizures. Lungs, which could cause severe breathing problems. Death (rare). […] Even with treatment, there might be long-term complications, including issues with your eyes, muscles and nerves. […] It may take weeks for you to feel better if you’ve had trichinosis. […] Most people enjoy a full recovery from trichinosis even though it may take weeks or even months to feel better completely. The outlook for severe cases of trichinosis that result in brain or heart damage is less positive.

• #21 Trichinosis – Infectious Diseases – Merck Manual Professional Edition

  https://www.merckmanuals.com/professional/infectious-diseases/nematodes-roundworms/trichinosis

  In heavy infections, the inflammation may cause complications: cardiac (myocarditis, heart failure, arrhythmia), neurologic (encephalitis, meningitis, visual or auditory disorders, seizures), or pulmonary (pneumonitis, pleurisy). Death may result from myocarditis or encephalitis. […] Symptoms and signs gradually resolve, and most disappear by about the third month, which is when the larvae have become fully encysted in muscle cells and eliminated from other organs and tissues. Vague muscular pains and fatigue may persist for many months.

• #22 Trichinosis | MedLink Neurology

  https://www.medlink.com/articles/trichinosis

  Trichinosis is an infectious disease caused by consumption of raw meat contaminated with larvae of nematode in the genus Trichinella. Clinical syndrome of Trichinella infection is caused by larvae migration and invasion of target tissues, primarily muscles causing muscle pain and swelling. Systemic symptoms include headache, maculopapular rash, focal edema, and local inflammation. Typical laboratory findings include leukocytosis and eosinophilia. Severity and prognosis depend on the parasitic burden. More than 1000 larvae per gram muscle is considered poor prognosis. The clinical manifestations of Trichinella infection vary depending on the phase of the disease and the number and sites of parasitic infestation. Phases include enteral phase (ranging from no symptoms to severe gastroenteritis), migratory phase, and parenteral phase (involving musculoskeletal muscles, bulbar muscles, cardiovascular systems, central nervous systems, and, rarely, renal systems). Central nervous system involvement accounts for 10% to 20% of Trichinella infections and may manifest as diffuse encephalopathy or as focal neurologic deficits. The first stage of infection manifests as a nonspecific gastroenteritis, which usually occurs 2 to 7 days after ingestion of contaminated food. Characteristic manifestations of Trichinella infection are caused by larvae migration and invasion of target tissues, primarily muscles. Tissue invasion by the larvae begins 6 to 10 days after exposure and is followed by encystment in muscle about two weeks later. The presence of more than 1000 larvae per gram of muscle is considered critical or fatal. Diffuse inflammatory response caused by larvae or their products leads to fever of varying degree and duration, headache, maculopapular rash, focal edema, local inflammation, leukocytosis, and eosinophilia. The most serious complications are related to involvement of the heart, central nervous system, and lungs. Cardiac involvement generally manifests in the form of myocarditis, which usually occurs during the third week of infection. Myocarditis is by far the most common cause of death in fatal trichinosis. Involvement of the central nervous system occurs in 10% to 20% of patients and is usually associated with heavy Trichinella infection. The mortality rates may be as high as 50%. Clinical manifestations of CNS trichinosis consist of both diffuse encephalopathy and focal neurologic deficits. The severity and prognosis of trichinosis in humans depends on the parasitic burden. In most cases, the symptoms are considered mild or even asymptomatic. On the other hand, the prognosis in patients with heavy larvae burden (more than 1000 larvae per gram of muscle) is poor and may be fatal.

• #23 Trichinosis

  https://science.jrank.org/pages/6955/Trichinosis-Symptoms-trichinosis.html

  The larvae begin to burrow into the host’s muscles and form cysts within about two to three weeks of the initial infection. This produces signs of muscle inflammation (myositis), including swelling of the affected muscle groups, pain, and weakness. […] Symptoms are at their most severe at about three weeks after infection and decrease very slowly in their severity. Recovery is extremely gradual, and symptoms may be present for as long as three months. Fatigue and myalgia (muscle pain) may take several more months to subside.

• #24 Trichinosis – Diagnosis & treatment – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/trichinosis/diagnosis-treatment/drc-20378587

  Trichinosis usually gets better on its own. In cases with a mild or moderate number of larvae, most signs and symptoms typically go away within a few months. However, fatigue, mild pain, weakness and diarrhea may stay for many months or years. Infection with a large number of larvae can cause more-severe symptoms that need treatment right away. […] Your health care provider may prescribe medications depending on your symptoms and the severity of infection. […] After the larvae have entered the muscles, your provider may prescribe pain relievers to help relieve muscle aches and pain and swelling (inflammation). Over time, the larvae cysts in your muscles tend to harden into calcium (calcify). As a result, the larvae die, and the muscle aches and weakness usually go away.

• #25 Trichinella spiralis Infection – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK538511/

  Trichinellosis usually has a benign course and is self-limiting. Full recovery of patients within 2 months to 6 months of infection is the expectation. However, some cases might be severe, and even death is a possibility. Death is rare if the cardiac and CNS remain uninvolved. Some individuals with CNS involvement may have residual deficits long-term. The prognosis of the disease proportionately correlates with the parasitic burden.

• #26 Trichinosis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK536945/

  There is a poor prognosis for severe cases that include cerebral or cardiac complications. Even with therapy, the mortality rate in those with severe infection is 5%. Milder cases have a good prognosis with symptoms disappearing in 2-6 months. […] After successful treatment, patients have complained of menstrual irregularities, hearing disorders, weight loss, hair and nail loss, skin desquamation, aphonia, muscle stiffness, and hoarseness. Heart failure or CNS failure in the 3-5 weeks of infection can lead to death. Other causes of death have been pneumonitis, encephalitis, myocarditis, hypokalemia, obstruction of blood vessel circulation, and adrenal gland insufficiency. Long-term complications include generalized myalgia, ocular symptoms such as conjunctivitis, and various neuropathies. These may persist up to 10 years post-recovery.

• #27 Trichinellosis (Trichinosis) | Texas DSHS

  https://www.dshs.texas.gov/notifiable-conditions/zoonosis-control/zoonosis-control-diseases-and-conditions/trichinellosis-trichinosis

  Diagnosis of trichinosis in man is often difficult because symptoms usually don’t occur until about a week after the infected meat is eaten; the clinical signs of the disease may be absent in the early stages and those noted in the later stages often simulate other diseases. Trichinosis is diagnosed by a blood test or by a biopsy of the muscle to identify the parasite.

• #28 FSHN10-05/FS153: The Cause of Trichinosis and Its Prevention Through Safe Food Handling Practices

  https://edis.ifas.ufl.edu/publication/FS153

  Trichinosis is an infection caused by roundworms in the genus Trichinella, with infection resulting primarily from food sources. […] Symptoms associated with trichinae in the intestines can begin as early as 12 days following infection, and further symptoms associated with larvae colonizing extraintestinal tissue will occur between 28 weeks after ingestion of the contaminated food. […] The severity of symptoms is directly related to how many larvae are ingested, with a larger amount producing more symptoms of greater severity. If very few larvae are ingested, the patient may be completely asymptomatic, or may experience very general flu-like symptoms that may never be properly diagnosed. In more serious infections, the patient may initially experience nausea, vomiting, diarrhea, and muscle pain, possibly followed by secondary diseases, such as neuro-trichinellosis, myocarditis, and dyspnea, if larvae migrate to brain, heart, or other vital tissues.

• #29 Trichinosis: Causes, symptoms, and treatment

  https://www.medicalnewstoday.com/articles/trichinosis

  Trichinosis is an infection with a particular roundworm parasite. It can occur as a result of eating raw or undercooked meat from infected animals. Infection may cause diarrhea, abdominal pain, and vomiting. […] In the later stages of infection, people may also experience muscle pain or fever. […] The severity of the symptoms that trichinosis causes may vary depending on the stage of the infection and the number of infectious worms that the person consumed in the meat. Some people may not experience any symptoms at all. […] The first symptoms usually occur 12 days after eating the infected meat. People may experience mild diarrhea, nausea, vomiting, and abdominal pain. […] The following symptoms may occur within 2 weeks of eating the contaminated meat and may last for up to 8 weeks: swelling in the face and around the eyes, muscle pain, fever, headaches, fatigue, itchy skin, chills, cough, diarrhea, and constipation. […] Treating trichinosis within the first 3 days of infection can prevent muscular invasion and disease progression. […] In more severe or advanced cases, people may experience serious symptoms involving the heart or brain.

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