Materiały źródłowe

• #1 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Acute leukemia requires aggressive, timely treatment. Chronic leukemia involves more-mature blood cells. These blood cells replicate or accumulate more slowly and can function normally for a period of time. Some forms of chronic leukemia initially produce no early symptoms and can go unnoticed or undiagnosed for years. […] A person with CML may have few or no symptoms for months or years before entering a phase in which the leukemia cells grow more quickly.

• #2 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  Having too many leukemia cells and too few normal cells is harmful for several reasons: Leukemia cells serve no purpose in keeping you healthy. Normal blood cells have very little space and support to mature and multiply inside of your bone marrow because the leukemia cells overtake them. Fewer red blood cells, healthy white blood cells and platelets are made and released into your blood. As a result, your bodys organs and tissues wont get the oxygen needed to work properly. Also, your body wont be able to fight infections or form blood clots when needed. […] If you have acute leukemia, youll feel sick within weeks of the leukemia cells forming. Acute leukemia is life-threatening and requires immediate initiation of therapy. […] If you have chronic leukemia, you may not have noticeable symptoms for years.

• #3 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  While some people with leukemia will experience obvious signs of the disease, others wont notice any changes at all which, oftentimes, is dependent on the type of leukemia they have (acute or chronic). […] Typically, acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL), tend to have a quick onset and can show more and recognizable symptoms early in the disease, whereas the chronic (slow onset) leukemias, chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL), tend to have delayed or mild symptoms. […] Some general symptoms of leukemia include: Fever, chills, Fatigue, Loss of appetite, Headaches, Unexplained weight loss, Night sweats, Bone/joint pain, Abdominal discomfort, Petechiae (small red spots under the skin). […] Symptoms include: Frequent infections and fever, Anemia, Easy bleeding or bruising, Joint and bone pain.

• #4 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #5 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  Symptoms include: Weakness, Dizziness or lightheadedness, Shortness of breath, Fever, Recurring or chronic infections, Bruising easily, Blood clotting issues such as frequent or severe nosebleeds and bleeding gums. […] Symptoms include: Tiredness, Shortness of breath, Decreased appetite or feeling full without eating much, Night sweats, Unexplained weight loss, Enlarged spleen and/or lymph nodes, Recurring or chronic infections in areas such as the skin, lungs or kidneys. […] Symptoms include: Weakness, Fatigue, Unexplained weight loss, Night sweats and/or fever, Bone pain, Abdominal pain or sense of fullness, Enlarged spleen. […] Even though some leukemia symptoms, such as fever, vomiting, fatigue, aches and night sweats often resemble the cold, flu or other common illness, its important that you pay attention to them. If these symptoms dont go away at a normal pace (1-2 weeks), or you notice a combination of these symptoms at one time, Rocky Mountain Cancer Centers recommends that you make an appointment with your primary care physician who will likely start with some blood tests to see what may be the root cause.

• #6 Leukemia symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/leukaemia-symptoms-signs/

  Leukemia symptoms commonly include fatigue, breathlessness, infections, and bruising or bleeding more easily. […] Most people with these symptoms wont have leukemia. But some people will, and the earlier its diagnosed, the higher the chance of treatment being successful. […] Even if you only have one symptom, if its unexplained, goes on for a long time, or is unusual for you, you should contact your GP. […] Leukemia symptoms commonly include: fatigue (tiredness that lasts a long time and doesnt improve with rest), bruising and bleeding more easily, or bleeding that takes longer to stop, infections that are more frequent, severe, or last longer, fever (high temperature), weight loss that is unexplained, swollen lymph nodes (glands in your neck, armpit and groin), breathlessness, feeling generally unwell.

• #7 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #8 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  Having too many leukemia cells and too few normal cells is harmful for several reasons: Leukemia cells serve no purpose in keeping you healthy. Normal blood cells have very little space and support to mature and multiply inside of your bone marrow because the leukemia cells overtake them. Fewer red blood cells, healthy white blood cells and platelets are made and released into your blood. As a result, your bodys organs and tissues wont get the oxygen needed to work properly. Also, your body wont be able to fight infections or form blood clots when needed. […] If you have acute leukemia, youll feel sick within weeks of the leukemia cells forming. Acute leukemia is life-threatening and requires immediate initiation of therapy. […] If you have chronic leukemia, you may not have noticeable symptoms for years.

• #9 Leukemia – Wikipedia

  https://en.wikipedia.org/wiki/Leukemia

  Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. […] These symptoms occur due to a lack of normal blood cells. […] Damage to the bone marrow, by way of displacing the normal bone marrow cells with higher numbers of immature white blood cells, results in a lack of blood platelets, which are important in the blood clotting process. This means people with leukemia may easily become bruised, bleed excessively, or develop pinprick bleeds (petechiae). […] White blood cells, which are involved in fighting pathogens, may be suppressed or dysfunctional. This could cause the person’s immune system to be unable to fight off a simple infection or to start attacking other body cells. […] Because leukemia prevents the immune system from working normally, some people experience frequent infection, ranging from infected tonsils, sores in the mouth, or diarrhea to life-threatening pneumonia or opportunistic infections.

• #10 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #11 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  Leukemia starts when the DNA of a single cell in your bone marrow changes (mutates) and cant develop and function normally. […] Symptoms depend, in part, on the type of leukemia. For instance, if you have a chronic form of leukemia, you may not have noticeable symptoms in the early stages. Common signs and symptoms of leukemia include: Fatigue, tiring easily. Fever or night sweats. Frequent infections. Shortness of breath. Pale skin. Unexplained weight loss. Bone/joint pain or tenderness. Pain or full feeling under your ribs on the left side. Swollen lymph nodes in your neck, underarm, groin or stomach, an enlarged spleen or liver. Bruising and bleeding easily, including nosebleeds, bleeding gums, a rash that looks like tiny red spots in skin (petechiae) or purplish/darkened skin patches.

• #12 12 Top Chronic Lymphocytic Leukemia Symptoms & Signs | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/chronic-lymphocytic-leukemia/chronic-lymphocytic-leukemia-symptoms.html

  While there are many different types of leukemia, the symptoms among these types can be similar. […] When CLL patients do develop symptoms, many are due to a lack of properly functioning blood cells to carry oxygen throughout the body, fight infection and stop bleeding. […] Leukemia symptoms include: Weakness, tiredness and fatigue. This can be caused by the leukemia itself or by the low levels of hemoglobin seen in many leukemia patients. […] Fever and frequent infections due to low counts of healthy white blood cells. […] Excessive sweating or night sweats […] Easy bleeding and bruising, including bleeding of the gums due to low platelet levels. […] Recurrent nose bleeds […] Petechiae, a rash-like collection of pinpoint spots on the skin caused by bleeding into the skin. This is also due to low levels of platelets.

• #13 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #14 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  While some people with leukemia will experience obvious signs of the disease, others wont notice any changes at all which, oftentimes, is dependent on the type of leukemia they have (acute or chronic). […] Typically, acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL), tend to have a quick onset and can show more and recognizable symptoms early in the disease, whereas the chronic (slow onset) leukemias, chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL), tend to have delayed or mild symptoms. […] Some general symptoms of leukemia include: Fever, chills, Fatigue, Loss of appetite, Headaches, Unexplained weight loss, Night sweats, Bone/joint pain, Abdominal discomfort, Petechiae (small red spots under the skin). […] Symptoms include: Frequent infections and fever, Anemia, Easy bleeding or bruising, Joint and bone pain.

• #15 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #16 12 Top Chronic Lymphocytic Leukemia Symptoms & Signs | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/chronic-lymphocytic-leukemia/chronic-lymphocytic-leukemia-symptoms.html

  While there are many different types of leukemia, the symptoms among these types can be similar. […] When CLL patients do develop symptoms, many are due to a lack of properly functioning blood cells to carry oxygen throughout the body, fight infection and stop bleeding. […] Leukemia symptoms include: Weakness, tiredness and fatigue. This can be caused by the leukemia itself or by the low levels of hemoglobin seen in many leukemia patients. […] Fever and frequent infections due to low counts of healthy white blood cells. […] Excessive sweating or night sweats […] Easy bleeding and bruising, including bleeding of the gums due to low platelet levels. […] Recurrent nose bleeds […] Petechiae, a rash-like collection of pinpoint spots on the skin caused by bleeding into the skin. This is also due to low levels of platelets.

• #17 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #18 12 Top Chronic Lymphocytic Leukemia Symptoms & Signs | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/chronic-lymphocytic-leukemia/chronic-lymphocytic-leukemia-symptoms.html

  Shortness of breath. This can be caused by low hemoglobin levels and lung infections. […] Swollen lymph nodes in the neck, underarm, stomach or groin […] Loss of appetite or a full feeling after eating very little food due to enlargement of the spleen […] Unexplained weight loss […] Bone and joint pain […] For female patients, longer than normal or heavier than normal menstruation.

• #19 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #20 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  Leukemia starts when the DNA of a single cell in your bone marrow changes (mutates) and cant develop and function normally. […] Symptoms depend, in part, on the type of leukemia. For instance, if you have a chronic form of leukemia, you may not have noticeable symptoms in the early stages. Common signs and symptoms of leukemia include: Fatigue, tiring easily. Fever or night sweats. Frequent infections. Shortness of breath. Pale skin. Unexplained weight loss. Bone/joint pain or tenderness. Pain or full feeling under your ribs on the left side. Swollen lymph nodes in your neck, underarm, groin or stomach, an enlarged spleen or liver. Bruising and bleeding easily, including nosebleeds, bleeding gums, a rash that looks like tiny red spots in skin (petechiae) or purplish/darkened skin patches.

• #21 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #22 12 Top Chronic Lymphocytic Leukemia Symptoms & Signs | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/chronic-lymphocytic-leukemia/chronic-lymphocytic-leukemia-symptoms.html

  While there are many different types of leukemia, the symptoms among these types can be similar. […] When CLL patients do develop symptoms, many are due to a lack of properly functioning blood cells to carry oxygen throughout the body, fight infection and stop bleeding. […] Leukemia symptoms include: Weakness, tiredness and fatigue. This can be caused by the leukemia itself or by the low levels of hemoglobin seen in many leukemia patients. […] Fever and frequent infections due to low counts of healthy white blood cells. […] Excessive sweating or night sweats […] Easy bleeding and bruising, including bleeding of the gums due to low platelet levels. […] Recurrent nose bleeds […] Petechiae, a rash-like collection of pinpoint spots on the skin caused by bleeding into the skin. This is also due to low levels of platelets.

• #23 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #24 12 Top Chronic Lymphocytic Leukemia Symptoms & Signs | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/chronic-lymphocytic-leukemia/chronic-lymphocytic-leukemia-symptoms.html

  While there are many different types of leukemia, the symptoms among these types can be similar. […] When CLL patients do develop symptoms, many are due to a lack of properly functioning blood cells to carry oxygen throughout the body, fight infection and stop bleeding. […] Leukemia symptoms include: Weakness, tiredness and fatigue. This can be caused by the leukemia itself or by the low levels of hemoglobin seen in many leukemia patients. […] Fever and frequent infections due to low counts of healthy white blood cells. […] Excessive sweating or night sweats […] Easy bleeding and bruising, including bleeding of the gums due to low platelet levels. […] Recurrent nose bleeds […] Petechiae, a rash-like collection of pinpoint spots on the skin caused by bleeding into the skin. This is also due to low levels of platelets.

• #25 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #26 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This might be noticed as a fullness or swelling of the belly, or feeling full after eating only a small amount. […] ALL that has spread to lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin, or in underarm areas), might be noticed as lumps under the skin. […] Sometimes leukemia cells build up near the surface of the bone or inside the joint, which can lead to bone or joint pain. […] If ALL spreads to the brain and spinal cord it can cause headaches, weakness, seizures, vomiting, trouble with balance, facial muscle weakness or numbness, or blurred vision. […] The T-cell subtype of ALL often affects the thymus, which is a small organ in the middle of the chest behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus can press on the trachea, which can lead to coughing or trouble breathing.

• #27 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #28 12 Top Chronic Lymphocytic Leukemia Symptoms & Signs | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/chronic-lymphocytic-leukemia/chronic-lymphocytic-leukemia-symptoms.html

  While there are many different types of leukemia, the symptoms among these types can be similar. […] When CLL patients do develop symptoms, many are due to a lack of properly functioning blood cells to carry oxygen throughout the body, fight infection and stop bleeding. […] Leukemia symptoms include: Weakness, tiredness and fatigue. This can be caused by the leukemia itself or by the low levels of hemoglobin seen in many leukemia patients. […] Fever and frequent infections due to low counts of healthy white blood cells. […] Excessive sweating or night sweats […] Easy bleeding and bruising, including bleeding of the gums due to low platelet levels. […] Recurrent nose bleeds […] Petechiae, a rash-like collection of pinpoint spots on the skin caused by bleeding into the skin. This is also due to low levels of platelets.

• #29 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #30 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  Leukemia starts when the DNA of a single cell in your bone marrow changes (mutates) and cant develop and function normally. […] Symptoms depend, in part, on the type of leukemia. For instance, if you have a chronic form of leukemia, you may not have noticeable symptoms in the early stages. Common signs and symptoms of leukemia include: Fatigue, tiring easily. Fever or night sweats. Frequent infections. Shortness of breath. Pale skin. Unexplained weight loss. Bone/joint pain or tenderness. Pain or full feeling under your ribs on the left side. Swollen lymph nodes in your neck, underarm, groin or stomach, an enlarged spleen or liver. Bruising and bleeding easily, including nosebleeds, bleeding gums, a rash that looks like tiny red spots in skin (petechiae) or purplish/darkened skin patches.

• #31 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  Leukemia starts when the DNA of a single cell in your bone marrow changes (mutates) and cant develop and function normally. […] Symptoms depend, in part, on the type of leukemia. For instance, if you have a chronic form of leukemia, you may not have noticeable symptoms in the early stages. Common signs and symptoms of leukemia include: Fatigue, tiring easily. Fever or night sweats. Frequent infections. Shortness of breath. Pale skin. Unexplained weight loss. Bone/joint pain or tenderness. Pain or full feeling under your ribs on the left side. Swollen lymph nodes in your neck, underarm, groin or stomach, an enlarged spleen or liver. Bruising and bleeding easily, including nosebleeds, bleeding gums, a rash that looks like tiny red spots in skin (petechiae) or purplish/darkened skin patches.

• #32 12 Top Chronic Lymphocytic Leukemia Symptoms & Signs | MD Anderson Cancer Center

  https://www.mdanderson.org/cancer-types/chronic-lymphocytic-leukemia/chronic-lymphocytic-leukemia-symptoms.html

  Shortness of breath. This can be caused by low hemoglobin levels and lung infections. […] Swollen lymph nodes in the neck, underarm, stomach or groin […] Loss of appetite or a full feeling after eating very little food due to enlargement of the spleen […] Unexplained weight loss […] Bone and joint pain […] For female patients, longer than normal or heavier than normal menstruation.

• #33 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Acute leukemia requires aggressive, timely treatment. Chronic leukemia involves more-mature blood cells. These blood cells replicate or accumulate more slowly and can function normally for a period of time. Some forms of chronic leukemia initially produce no early symptoms and can go unnoticed or undiagnosed for years. […] A person with CML may have few or no symptoms for months or years before entering a phase in which the leukemia cells grow more quickly.

• #34 Symptoms of leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/leukemia/signs-and-symptoms

  The signs or symptoms of leukemia may vary depending on whether you have an acute or chronic type of leukemia. […] Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. […] Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test. […] Other health conditions can cause the same symptoms as leukemia. […] Fatigue, a general feeling of discomfort or illness (called malaise), loss of appetite, weight loss, fever, shortness of breath, paleness, rapid heartbeat (called palpitations), weakness, dizziness, easy bruising, frequent or severe nose bleeds, bleeding gums, bleeding in the middle of a menstrual cycle or heavy menstrual flow, tiny, flat, red spots caused by bleeding just under the surface of the skin (called petechiae), frequent infections in the lungs, urinary tract or gums or around the anus, frequent cold sores, vomiting, headache, sore throat, night sweats, bone or joint pain, enlarged lymph nodes in the neck, underarm, groin or above the collarbone, abdominal discomfort or feeling of fullness, vision problems, sores in the eyes, swelling of the testicles, chloroma a collection of leukemia cells, or blasts, under the skin or in other parts of the body, leukemia cutis appears as sores or as patches of any size that are usually pink or tan in colour, leukocytoclastic vasculitis a condition that looks like an allergic reaction on the skin and usually causes sores on the hands and feet, Sweets syndrome, or acute febrile neutrophilic dermatosis causes fever and painful sores that may appear anywhere on the body.

• #35 Symptoms of leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/leukemia/signs-and-symptoms

  The signs or symptoms of leukemia may vary depending on whether you have an acute or chronic type of leukemia. […] Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. […] Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test. […] Other health conditions can cause the same symptoms as leukemia. […] Fatigue, a general feeling of discomfort or illness (called malaise), loss of appetite, weight loss, fever, shortness of breath, paleness, rapid heartbeat (called palpitations), weakness, dizziness, easy bruising, frequent or severe nose bleeds, bleeding gums, bleeding in the middle of a menstrual cycle or heavy menstrual flow, tiny, flat, red spots caused by bleeding just under the surface of the skin (called petechiae), frequent infections in the lungs, urinary tract or gums or around the anus, frequent cold sores, vomiting, headache, sore throat, night sweats, bone or joint pain, enlarged lymph nodes in the neck, underarm, groin or above the collarbone, abdominal discomfort or feeling of fullness, vision problems, sores in the eyes, swelling of the testicles, chloroma a collection of leukemia cells, or blasts, under the skin or in other parts of the body, leukemia cutis appears as sores or as patches of any size that are usually pink or tan in colour, leukocytoclastic vasculitis a condition that looks like an allergic reaction on the skin and usually causes sores on the hands and feet, Sweets syndrome, or acute febrile neutrophilic dermatosis causes fever and painful sores that may appear anywhere on the body.

• #36 Common Leukemia Symptoms & Signs | Memorial Sloan Kettering Cancer Center | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/leukemias/symptoms

  In both acute and chronic leukemias, as the number of leukemic cells increases, normal cells are crowded out of the bone marrow and symptoms may begin to develop. […] The symptoms of acute leukemia generally appear suddenly and can also be similar to those of a virus or flu. Symptoms can be severe enough that they prompt patients to see a doctor soon after their onset. […] When chronic leukemia first develops, symptoms may not arise for several years. CLL and CML are often discovered as an incidental finding of an elevated white blood cell count during the routine blood tests that are part of a regular checkup. With the passage of time, however, as the number of diseased cells increases they may infiltrate the bone marrow and/or other organs to the point that they cause significant problems.

• #37 How fast does leukemia develop? | Roswell Park Comprehensive Cancer Center – Buffalo, NY

  https://www.roswellpark.org/cancertalk/201810/how-fast-does-leukemia-develop

  Leukemia is a cancer of the blood. It begins when the bone marrow starts to rapidly produce abnormal white blood cells called leukemia cells. They may crowd out normal white blood cells, red blood cells, and platelets, making it hard for the normal cells to do their work. […] Acute leukemias which are incredibly rare are the most rapidly progressing cancer we know of. The white cells in the blood grow very quickly, over a matter of days to weeks. […] Extreme fatigue is usually the first symptom that causes acute leukemia patients to seek medical care. Theyre tired for no apparent reason. […] Its also common for these patients to develop pneumonia or some sort of infection. […] At the time of diagnosis, patients can have very, very high white blood cell counts. […] When patients have very high white blood cell counts, the leukemia cells will usually spill over from the blood vessels into some of the organs.

• #38 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  Early symptoms of leukemia often include easy bleeding, frequent infections, and fatigue. In the late stages, you might develop symptoms such as confusion, slow breathing, and hallucinations. […] Symptoms of acute leukemia often develop over a few weeks. Some of the early symptoms, such as fever and lethargy, may mimic those of the flu. Other possible early symptoms include: frequent infections, abnormal bleeding, such as: excessive bleeding, even from small wounds, easy bruising, bleeding of your gums, heavy menstrual bleeding, frequent nosebleeds, swollen liver or swollen spleen, swollen lymph nodes, pain in your spine or your long bones, anemia symptoms, such as: shortness of breath, headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness.

• #39 How fast does leukemia develop? | Roswell Park Comprehensive Cancer Center – Buffalo, NY

  https://www.roswellpark.org/cancertalk/201810/how-fast-does-leukemia-develop

  Leukemia is a cancer of the blood. It begins when the bone marrow starts to rapidly produce abnormal white blood cells called leukemia cells. They may crowd out normal white blood cells, red blood cells, and platelets, making it hard for the normal cells to do their work. […] Acute leukemias which are incredibly rare are the most rapidly progressing cancer we know of. The white cells in the blood grow very quickly, over a matter of days to weeks. […] Extreme fatigue is usually the first symptom that causes acute leukemia patients to seek medical care. Theyre tired for no apparent reason. […] Its also common for these patients to develop pneumonia or some sort of infection. […] At the time of diagnosis, patients can have very, very high white blood cell counts. […] When patients have very high white blood cell counts, the leukemia cells will usually spill over from the blood vessels into some of the organs.

• #40 How fast does leukemia develop? | Roswell Park Comprehensive Cancer Center – Buffalo, NY

  https://www.roswellpark.org/cancertalk/201810/how-fast-does-leukemia-develop

  Leukemia is a cancer of the blood. It begins when the bone marrow starts to rapidly produce abnormal white blood cells called leukemia cells. They may crowd out normal white blood cells, red blood cells, and platelets, making it hard for the normal cells to do their work. […] Acute leukemias which are incredibly rare are the most rapidly progressing cancer we know of. The white cells in the blood grow very quickly, over a matter of days to weeks. […] Extreme fatigue is usually the first symptom that causes acute leukemia patients to seek medical care. Theyre tired for no apparent reason. […] Its also common for these patients to develop pneumonia or some sort of infection. […] At the time of diagnosis, patients can have very, very high white blood cell counts. […] When patients have very high white blood cell counts, the leukemia cells will usually spill over from the blood vessels into some of the organs.

• #41 How fast does leukemia develop? | Roswell Park Comprehensive Cancer Center – Buffalo, NY

  https://www.roswellpark.org/cancertalk/201810/how-fast-does-leukemia-develop

  Leukemia is a cancer of the blood. It begins when the bone marrow starts to rapidly produce abnormal white blood cells called leukemia cells. They may crowd out normal white blood cells, red blood cells, and platelets, making it hard for the normal cells to do their work. […] Acute leukemias which are incredibly rare are the most rapidly progressing cancer we know of. The white cells in the blood grow very quickly, over a matter of days to weeks. […] Extreme fatigue is usually the first symptom that causes acute leukemia patients to seek medical care. Theyre tired for no apparent reason. […] Its also common for these patients to develop pneumonia or some sort of infection. […] At the time of diagnosis, patients can have very, very high white blood cell counts. […] When patients have very high white blood cell counts, the leukemia cells will usually spill over from the blood vessels into some of the organs.

• #42 How fast does leukemia develop? | Roswell Park Comprehensive Cancer Center – Buffalo, NY

  https://www.roswellpark.org/cancertalk/201810/how-fast-does-leukemia-develop

  Leukemia is a cancer of the blood. It begins when the bone marrow starts to rapidly produce abnormal white blood cells called leukemia cells. They may crowd out normal white blood cells, red blood cells, and platelets, making it hard for the normal cells to do their work. […] Acute leukemias which are incredibly rare are the most rapidly progressing cancer we know of. The white cells in the blood grow very quickly, over a matter of days to weeks. […] Extreme fatigue is usually the first symptom that causes acute leukemia patients to seek medical care. Theyre tired for no apparent reason. […] Its also common for these patients to develop pneumonia or some sort of infection. […] At the time of diagnosis, patients can have very, very high white blood cell counts. […] When patients have very high white blood cell counts, the leukemia cells will usually spill over from the blood vessels into some of the organs.

• #43 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This might be noticed as a fullness or swelling of the belly, or feeling full after eating only a small amount. […] ALL that has spread to lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin, or in underarm areas), might be noticed as lumps under the skin. […] Sometimes leukemia cells build up near the surface of the bone or inside the joint, which can lead to bone or joint pain. […] If ALL spreads to the brain and spinal cord it can cause headaches, weakness, seizures, vomiting, trouble with balance, facial muscle weakness or numbness, or blurred vision. […] The T-cell subtype of ALL often affects the thymus, which is a small organ in the middle of the chest behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus can press on the trachea, which can lead to coughing or trouble breathing.

• #44 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This might be noticed as a fullness or swelling of the belly, or feeling full after eating only a small amount. […] ALL that has spread to lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin, or in underarm areas), might be noticed as lumps under the skin. […] Sometimes leukemia cells build up near the surface of the bone or inside the joint, which can lead to bone or joint pain. […] If ALL spreads to the brain and spinal cord it can cause headaches, weakness, seizures, vomiting, trouble with balance, facial muscle weakness or numbness, or blurred vision. […] The T-cell subtype of ALL often affects the thymus, which is a small organ in the middle of the chest behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus can press on the trachea, which can lead to coughing or trouble breathing.

• #45 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  While some people with leukemia will experience obvious signs of the disease, others wont notice any changes at all which, oftentimes, is dependent on the type of leukemia they have (acute or chronic). […] Typically, acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL), tend to have a quick onset and can show more and recognizable symptoms early in the disease, whereas the chronic (slow onset) leukemias, chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL), tend to have delayed or mild symptoms. […] Some general symptoms of leukemia include: Fever, chills, Fatigue, Loss of appetite, Headaches, Unexplained weight loss, Night sweats, Bone/joint pain, Abdominal discomfort, Petechiae (small red spots under the skin). […] Symptoms include: Frequent infections and fever, Anemia, Easy bleeding or bruising, Joint and bone pain.

• #46 Signs and Symptoms of Leukemia | From Oregon Cancer Specialists

  https://www.compassoncology.com/leukemia/signs-symptoms

  Not everyone with leukemia experiences symptoms in the early stages, depending on the type of the disease (acute or chronic). […] Acute myeloid leukemia (AML) and acute lymphocytic leukemia (ALL), tend to have a quick onset and can show more and recognizable symptoms early in the disease, whereas the chronic (slow onset) leukemias, chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL), tend to have delayed or mild symptoms. […] Some general symptoms of leukemia include: Fever, chills, Fatigue, Loss of appetite, Headaches, Unexplained weight loss, Night sweats, Bone/joint pain, Abdominal discomfort, Petechiae (small red spots under the skin). […] Symptoms specific to this type of leukemia include: Frequent infections and fever, Anemia, Easy bleeding or bruising, Joint and bone pain.

• #47 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Acute leukemia requires aggressive, timely treatment. Chronic leukemia involves more-mature blood cells. These blood cells replicate or accumulate more slowly and can function normally for a period of time. Some forms of chronic leukemia initially produce no early symptoms and can go unnoticed or undiagnosed for years. […] A person with CML may have few or no symptoms for months or years before entering a phase in which the leukemia cells grow more quickly.

• #48 How fast does leukemia develop? | Roswell Park Comprehensive Cancer Center – Buffalo, NY

  https://www.roswellpark.org/cancertalk/201810/how-fast-does-leukemia-develop

  Low platelets can also cause petechiae, little breaks in the smallest blood vessels that cause blood to leak into the skin. […] Unlike acute leukemia, chronic leukemia develops slowly. It may take months or even several years before the disease begins to cause symptoms that alert the patient that something is wrong. […] If a patient doesnt see a doctor for several years, the disease can go undetected over a long period of time, and the abnormal cells can build up and cause an enlarged spleen. […] Chronic leukemias can be controlled or treated in much the same way as other chronic disorders, such as high blood pressure.

• #49 Symptoms of chronic lymphocytic leukaemia (CLL) | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/chronic-lymphocytic-leukaemia-cll/symptoms

  Many people with chronic lymphocytic leukaemia (CLL) won’t have any symptoms at all. […] In CLL, symptoms tend to be mild at first and get worse slowly. Many symptoms are vague. You may feel as if you had the flu. […] Symptoms of CLL include: swollen lymph glands or tummy (abdominal) discomfort from an enlarged spleen, weight loss, infections that will not get better, feeling tired, anaemia, bleeding or bruising, bone pain or night sweats. […] You may also get an enlarged spleen. The spleen is an organ on the left of your body, just under your ribs. If your spleen becomes much bigger than normal, it can be uncomfortable or painful. […] CLL itself uses up energy that your body would otherwise use or store. So you may lose weight, even if you eat normally. […] As the number of abnormal white blood cells rise, you may pick up infections more easily. This is because the abnormal white blood cells cannot fight off infection as well as healthy ones.

• #50 Symptoms of chronic lymphocytic leukaemia (CLL) | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/chronic-lymphocytic-leukaemia-cll/symptoms

  Many people with chronic lymphocytic leukaemia (CLL) won’t have any symptoms at all. […] In CLL, symptoms tend to be mild at first and get worse slowly. Many symptoms are vague. You may feel as if you had the flu. […] Symptoms of CLL include: swollen lymph glands or tummy (abdominal) discomfort from an enlarged spleen, weight loss, infections that will not get better, feeling tired, anaemia, bleeding or bruising, bone pain or night sweats. […] You may also get an enlarged spleen. The spleen is an organ on the left of your body, just under your ribs. If your spleen becomes much bigger than normal, it can be uncomfortable or painful. […] CLL itself uses up energy that your body would otherwise use or store. So you may lose weight, even if you eat normally. […] As the number of abnormal white blood cells rise, you may pick up infections more easily. This is because the abnormal white blood cells cannot fight off infection as well as healthy ones.

• #51 Symptoms of leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/leukemia/signs-and-symptoms

  The signs or symptoms of leukemia may vary depending on whether you have an acute or chronic type of leukemia. […] Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. […] Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test. […] Other health conditions can cause the same symptoms as leukemia. […] Fatigue, a general feeling of discomfort or illness (called malaise), loss of appetite, weight loss, fever, shortness of breath, paleness, rapid heartbeat (called palpitations), weakness, dizziness, easy bruising, frequent or severe nose bleeds, bleeding gums, bleeding in the middle of a menstrual cycle or heavy menstrual flow, tiny, flat, red spots caused by bleeding just under the surface of the skin (called petechiae), frequent infections in the lungs, urinary tract or gums or around the anus, frequent cold sores, vomiting, headache, sore throat, night sweats, bone or joint pain, enlarged lymph nodes in the neck, underarm, groin or above the collarbone, abdominal discomfort or feeling of fullness, vision problems, sores in the eyes, swelling of the testicles, chloroma a collection of leukemia cells, or blasts, under the skin or in other parts of the body, leukemia cutis appears as sores or as patches of any size that are usually pink or tan in colour, leukocytoclastic vasculitis a condition that looks like an allergic reaction on the skin and usually causes sores on the hands and feet, Sweets syndrome, or acute febrile neutrophilic dermatosis causes fever and painful sores that may appear anywhere on the body.

• #52 Common Leukemia Symptoms & Signs | Memorial Sloan Kettering Cancer Center | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/types/leukemias/symptoms

  In both acute and chronic leukemias, as the number of leukemic cells increases, normal cells are crowded out of the bone marrow and symptoms may begin to develop. […] The symptoms of acute leukemia generally appear suddenly and can also be similar to those of a virus or flu. Symptoms can be severe enough that they prompt patients to see a doctor soon after their onset. […] When chronic leukemia first develops, symptoms may not arise for several years. CLL and CML are often discovered as an incidental finding of an elevated white blood cell count during the routine blood tests that are part of a regular checkup. With the passage of time, however, as the number of diseased cells increases they may infiltrate the bone marrow and/or other organs to the point that they cause significant problems.

• #53 Symptoms of leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/leukemia/signs-and-symptoms

  The signs or symptoms of leukemia may vary depending on whether you have an acute or chronic type of leukemia. […] Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. […] Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test. […] Other health conditions can cause the same symptoms as leukemia. […] Fatigue, a general feeling of discomfort or illness (called malaise), loss of appetite, weight loss, fever, shortness of breath, paleness, rapid heartbeat (called palpitations), weakness, dizziness, easy bruising, frequent or severe nose bleeds, bleeding gums, bleeding in the middle of a menstrual cycle or heavy menstrual flow, tiny, flat, red spots caused by bleeding just under the surface of the skin (called petechiae), frequent infections in the lungs, urinary tract or gums or around the anus, frequent cold sores, vomiting, headache, sore throat, night sweats, bone or joint pain, enlarged lymph nodes in the neck, underarm, groin or above the collarbone, abdominal discomfort or feeling of fullness, vision problems, sores in the eyes, swelling of the testicles, chloroma a collection of leukemia cells, or blasts, under the skin or in other parts of the body, leukemia cutis appears as sores or as patches of any size that are usually pink or tan in colour, leukocytoclastic vasculitis a condition that looks like an allergic reaction on the skin and usually causes sores on the hands and feet, Sweets syndrome, or acute febrile neutrophilic dermatosis causes fever and painful sores that may appear anywhere on the body.

• #54 Patient education: Chronic lymphocytic leukemia (CLL) in adults (Beyond the Basics) – UpToDate

  https://www.uptodate.com/contents/chronic-lymphocytic-leukemia-cll-in-adults-beyond-the-basics/print

  As mentioned, most people do not have symptoms when they are diagnosed with CLL, and the disease is discovered after a routine blood test shows abnormalities. However, some people do experience symptoms before diagnosis. The most common symptom is enlarged lymph nodes, most often in the neck, armpit, or groin areas. Less commonly, people with CLL notice other symptoms, including fatigue, unintentional weight loss, chronic fever (without other signs of infection), or night sweats. […] The progression of CLL can vary considerably from one person to another. Some people become sick within a short time of diagnosis; others live comfortably for years without problems. […] The decision to start treatment is impacted by whether or not there are symptoms. […] However, there are certain groups of people in whom doctors generally recommend treatment. This includes people with symptoms of anemia and/or low platelets, disease-related symptoms such as severe fatigue, night sweats, unintentional weight loss, painful swelling of lymph nodes or spleen, or unexplained fever, extremely enlarged lymph nodes or spleen, complications from involvement of other organs, autoimmune hemolytic anemia, or cancer that is progressing quickly.

• #55 4 Signs and 5 Symptoms of CLL | MyLeukemiaTeam

  https://www.myleukemiateam.com/resources/signs-and-symptoms-of-chronic-lymphocytic-leukemia

  B symptoms are systemic (whole-body) symptoms that occur without another obvious cause, such as infection. They can be a sign of disease progression and may signal the need to start CLL treatment. […] During later stages of CLL, as the disease gets worse, some people may develop splenomegaly an enlarged spleen. […] Additionally, CLL can weaken the immune system. […] People with CLL often have low levels of healthy blood cells. This happens because leukemia cells build up in the bone marrow the spongy tissue inside bones where new blood cells are made. […] Many people with CLL develop anemia low red blood cell counts. […] Thrombocytopenia low levels of platelets is another sign of CLL. […] During later stages of CLL, as the disease gets worse, some people may develop splenomegaly an enlarged spleen. […] In advanced stages of CLL, enlarged lymph nodes may occur.

• #56 Symptoms of chronic lymphocytic leukaemia (CLL) | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/chronic-lymphocytic-leukaemia-cll/symptoms

  Many people with chronic lymphocytic leukaemia (CLL) won’t have any symptoms at all. […] In CLL, symptoms tend to be mild at first and get worse slowly. Many symptoms are vague. You may feel as if you had the flu. […] Symptoms of CLL include: swollen lymph glands or tummy (abdominal) discomfort from an enlarged spleen, weight loss, infections that will not get better, feeling tired, anaemia, bleeding or bruising, bone pain or night sweats. […] You may also get an enlarged spleen. The spleen is an organ on the left of your body, just under your ribs. If your spleen becomes much bigger than normal, it can be uncomfortable or painful. […] CLL itself uses up energy that your body would otherwise use or store. So you may lose weight, even if you eat normally. […] As the number of abnormal white blood cells rise, you may pick up infections more easily. This is because the abnormal white blood cells cannot fight off infection as well as healthy ones.

• #57 Leukemia Symptoms: ALL, AML, CLL and CML | Leukemia Diagnosis and Treatment | University of Michigan Rogel Cancer Center

  https://www.rogelcancercenter.org/leukemia/symptoms

  The symptoms of leukemia depend on the number of leukemia cells and where these cells collect in the body. […] Possible signs of adult Acute Myeloid Leukemia include fever, shortness of breath, easy bruising or bleeding, petechiae (flat, pinpoint spots under the skin caused by bleeding), weakness or feeling tired, and weight loss or loss of appetite. […] Possible signs of Acute Lymphocytic Leukemia include weakness or feeling tired, fever or night sweats, easy bruising or bleeding, petechiae (flat, pinpoint spots under the skin caused by bleeding), shortness of breath, weight loss or loss of appetite, pain in the bones or stomach, pain or feeling of fullness below the ribs, painless lumps in the neck, underarm, stomach, or groin, and having many infections. […] Possible signs of Chronic Lymphocytic Leukemia include painless swelling of the lymph nodes in the neck, underarm, stomach, or groin, feeling very tired, pain or fullness below the ribs, fever and infection, and weight loss for no known reason. […] Possible signs of Chronic Myeloid Leukemia include feeling very tired, weight loss for no known reason, night sweats, fever, and pain or a feeling of fullness below the ribs on the left side. Sometimes CML does not cause any symptoms at all.

• #58 4 Signs and 5 Symptoms of CLL | MyLeukemiaTeam

  https://www.myleukemiateam.com/resources/signs-and-symptoms-of-chronic-lymphocytic-leukemia

  Chronic lymphocytic leukemia (CLL) is a slow-growing type of blood cancer. It often doesnt cause symptoms right away even when signs of the condition. […] About 50 percent to 75 percent of people with CLL dont have symptoms when theyre first diagnosed. Symptoms often appear later as CLL gets worse. […] Extreme Tiredness. Tiredness caused by CLL is sometimes called cancer-related fatigue. This type of exhaustion can affect you physically, mentally, or emotionally. Unlike regular tiredness, it doesnt get better with sleep and rest. […] Shortness of breath related to CLL may start suddenly or get worse over time. You might feel out of breath after finishing a task that used to be easy for you. If shortness of breath lasts more than one month, especially with a persistent cough, it could be a symptom of CLL.

• #59 Symptoms of adult chronic and acute leukaemia before diagnosis: large primary care case-control studies using electronic records

  https://pmc.ncbi.nlm.nih.gov/articles/PMC4758497/

  Leukaemia is the eleventh commonest UK cancer. The four main subtypes have different clinical profiles, particularly between chronic and acute types. […] To identify the symptom profiles of chronic and acute leukaemia in adults in primary care. […] Ten symptoms were independently associated with CL, the three strongest being: lymphadenopathy (odds ratio [OR] 22, 95% confidence interval [CI] = 13 to 36), weight loss (OR 3.0, 95% CI = 2.1 to 4.2), and bruising (OR 2.3, 95% CI = 1.6 to 3.2). Thirteen symptoms were independently associated with AL, the three strongest being: nosebleeds and/or bleeding gums (OR 5.7, 95% CI = 3.1 to 10), fever (OR 5.3, 95% CI = 2.7 to 10), and fatigue (OR 4.4, 95% CI = 3.3 to 6.0). […] The symptom profiles of CL and AL have both overlapping and distinct features.

• #60 Leukemia: Symptoms, Signs, Causes, Types, and More

  https://www.healthline.com/health/leukemia

  Leukemia can refer to all cancers affecting the white blood cells. How the cancer spreads can depend on the type of leukemia and how aggressive it is. […] In leukemia, the WBCs do not function like normal WBCs. They divide too quickly and eventually crowd out normal blood cells. […] The symptoms of leukemia may include: excessive sweating, especially at night (night sweats), fatigue and weakness that do not go away with rest, unintentional weight loss, bone pain and tenderness, painless, swollen lymph nodes, especially in the neck and armpits, enlarged liver or spleen, red spots on the skin, called petechiae, bleeding easily and bruising easily, fever or chills, frequent infections. […] How the cancer spreads depends on the type of leukemia and how aggressive it is. Parts of your body that leukemia can spread to include the lungs, gastrointestinal tract, heart, kidneys, testicles. […] Acute myeloid leukemia (AML) is the most aggressive type of leukemia. It progresses rapidly and requires immediate treatment.

• #61 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #62 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #63 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  A shortage of blood platelets is called thrombocytopenia. This can lead to: Bruises (or small red or purple spots) on the skin, Excess bleeding, Frequent or severe nosebleeds, Bleeding gums, Heavy periods (menstrual bleeding) in women. […] The cancer cells in AML (called blasts) are bigger than normal blood cells and have more trouble traveling through tiny blood vessels. If the blast count gets very high, these cells can clog up blood vessels and make it hard for normal red blood cells (and oxygen) to get to tissues. This is called leukostasis. […] People with a certain type of AML called acute promyelocytic leukemia (APL) might have problems with bleeding and blood clotting. […] Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas.

• #64 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  A shortage of blood platelets is called thrombocytopenia. This can lead to: Bruises (or small red or purple spots) on the skin, Excess bleeding, Frequent or severe nosebleeds, Bleeding gums, Heavy periods (menstrual bleeding) in women. […] The cancer cells in AML (called blasts) are bigger than normal blood cells and have more trouble traveling through tiny blood vessels. If the blast count gets very high, these cells can clog up blood vessels and make it hard for normal red blood cells (and oxygen) to get to tissues. This is called leukostasis. […] People with a certain type of AML called acute promyelocytic leukemia (APL) might have problems with bleeding and blood clotting. […] Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas.

• #65 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #66 Blood cancer signs and symptoms – Leukaemia Foundation

  https://www.leukaemia.org.au/blood-cancer/blood-cancer-signs-and-symptoms/

  Blood cancer symptoms can be vague and easy to overlook, but it’s important to pay attention to changes in your body. Some of the most common signs include unexplained weight loss, fatigue, frequent infections, easy bruising or bleeding, night sweats, shortness of breath, and unusual lumps or swellings. If you notice any of these symptoms or something just doesn’t feel right, speak with your doctor. The earlier blood cancer is detected, the better the chances of successful treatment. […] Cause: very high level of white blood cells. Some types of blood cancer such as acute myeloid leukaemia (AML) develop very quickly. You may suddenly become very unwell. This is known as leukostasis. […] Not everyone will have the same symptoms, some people may have symptoms that are not listed here. Usually multiple symptoms are present and develop quickly. […] Leukostasis is a medical emergency and you must seek medical attention immediately. Call 000 – for a medical emergency.

• #67 Leukemia Symptoms by Stage and Type

  https://www.verywellhealth.com/leukemia-signs-and-symptoms-2252435

  With the proliferation of leukemic cells in the body, the symptoms of leukemia can become more unmistakable. As the number of white blood cells continues to drop, your ability to fight infection will decrease. The decline in red blood cells and platelets will also account for the worsening of anemia and thrombocytopenia. […] Additional symptoms will develop as leukemic cells start to invade other organs, including the central nervous system (comprised of the brain and spinal cord). […] Common symptoms of leukemia include headache, fatigue, fever, swollen lymph nodes, swollen abdomen, easy bruising or bleeding, red skin spots, night sweats, frequent infections, pale skin, bone pain, and unexplained weight loss. These and other symptoms can appear suddenly if you have acute leukemia or appear gradually if you have chronic leukemia.

• #68 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Signs and symptoms are changes in the body that may indicate disease. A person who has signs or symptoms that suggest the possibility of leukemia is usually referred to a specialist. It is common for someone with ALL to feel a loss of well-being because of the underproduction of normal blood cells. Consequently, patients with ALL do not have sufficient numbers of mature red blood cells, white blood cells and platelets. […] Symptoms of anemia (low red blood cell count) include fatigue, shortness of breath during normal physical activities, dizziness, and pale complexion. […] Symptoms of neutropenia (low number of neutrophils, a type of white blood cells) include frequent infections and fever. […] Symptoms of thrombocytopenia (low platelet count) include bruising easily, prolonged bleeding from minor cuts, the appearance of pinhead-sized red spots on the skin, called petechiae, frequent or severe nosebleeds, bleeding gums, and heavier or more frequent menstrual periods.

• #69 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Signs and symptoms are changes in the body that may indicate disease. A person who has signs or symptoms that suggest the possibility of leukemia is usually referred to a specialist. It is common for someone with ALL to feel a loss of well-being because of the underproduction of normal blood cells. Consequently, patients with ALL do not have sufficient numbers of mature red blood cells, white blood cells and platelets. […] Symptoms of anemia (low red blood cell count) include fatigue, shortness of breath during normal physical activities, dizziness, and pale complexion. […] Symptoms of neutropenia (low number of neutrophils, a type of white blood cells) include frequent infections and fever. […] Symptoms of thrombocytopenia (low platelet count) include bruising easily, prolonged bleeding from minor cuts, the appearance of pinhead-sized red spots on the skin, called petechiae, frequent or severe nosebleeds, bleeding gums, and heavier or more frequent menstrual periods.

• #70 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Signs and symptoms are changes in the body that may indicate disease. A person who has signs or symptoms that suggest the possibility of leukemia is usually referred to a specialist. It is common for someone with ALL to feel a loss of well-being because of the underproduction of normal blood cells. Consequently, patients with ALL do not have sufficient numbers of mature red blood cells, white blood cells and platelets. […] Symptoms of anemia (low red blood cell count) include fatigue, shortness of breath during normal physical activities, dizziness, and pale complexion. […] Symptoms of neutropenia (low number of neutrophils, a type of white blood cells) include frequent infections and fever. […] Symptoms of thrombocytopenia (low platelet count) include bruising easily, prolonged bleeding from minor cuts, the appearance of pinhead-sized red spots on the skin, called petechiae, frequent or severe nosebleeds, bleeding gums, and heavier or more frequent menstrual periods.

• #71 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Other general symptoms of ALL include night sweats, discomfort in bones or joints, enlarged spleen, liver or lymph nodes, pain or feeling of fullness below the ribs, unexplained weight loss or loss of appetite, and wheezing, coughing or painful breathing. […] The signs and symptoms of acute lymphoblastic leukemia (ALL) are common to other, less serious illnesses. However, if you’re troubled by any of these symptoms, see your doctor.

• #72 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Other general symptoms of ALL include night sweats, discomfort in bones or joints, enlarged spleen, liver or lymph nodes, pain or feeling of fullness below the ribs, unexplained weight loss or loss of appetite, and wheezing, coughing or painful breathing. […] The signs and symptoms of acute lymphoblastic leukemia (ALL) are common to other, less serious illnesses. However, if you’re troubled by any of these symptoms, see your doctor.

• #73 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This might be noticed as a fullness or swelling of the belly, or feeling full after eating only a small amount. […] ALL that has spread to lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin, or in underarm areas), might be noticed as lumps under the skin. […] Sometimes leukemia cells build up near the surface of the bone or inside the joint, which can lead to bone or joint pain. […] If ALL spreads to the brain and spinal cord it can cause headaches, weakness, seizures, vomiting, trouble with balance, facial muscle weakness or numbness, or blurred vision. […] The T-cell subtype of ALL often affects the thymus, which is a small organ in the middle of the chest behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus can press on the trachea, which can lead to coughing or trouble breathing.

• #74 Leukemia Symptoms and Signs

  https://www.webmd.com/cancer/lymphoma/understanding-leukemia-symptoms

  Acute myeloid leukemia is a common cancer in children but happens more often in adults. Symptoms may include: Fever, Difficulty breathing, Red spots under the skin, Easily bleeding or bruising, Tiredness, Weakness, Loss of appetite, Unexplained weight loss […] Chronic lymphocytic leukemia is the most common leukemia in adults in Western countries. It makes up 25%-30% of leukemia cases in the U.S. You may show no symptoms at first. However, over time, you may start having symptoms such as: Tiredness, Weakness, Pain or a feeling of fullness under the ribs, Swollen lymph nodes, Fever, Frequent infections, Bruising or bleeding easily, Red spots, Unexplained weight loss […] At first, leukemia may cause many symptoms that are similar to less serious health conditions. But as it progresses, symptoms may become more noticeable, distressing, and potentially life-threatening. See a doctor immediately about any new unexplained symptoms that dont go away whether or not youve been diagnosed with leukemia.

• #75 Chronic lymphocytic leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-lymphocytic-leukemia/symptoms-causes/syc-20352428

  Chronic lymphocytic leukemia most commonly affects older adults. […] Many people with chronic lymphocytic leukemia have no symptoms at first. Signs and symptoms might develop as the cancer progresses. They might include: […] Enlarged, but painless, lymph nodes […] Fatigue […] Fever […] Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen […] Night sweats […] Weight loss […] Frequent infections.

• #76 Chronic Lymphocytic Leukemia – Leukemia Research Foundation

  https://leukemiarf.org/leukemia/chronic-lymphocytic-leukemia/

  Chronic lymphocytic leukemia grows slowly, so many people dont experience any symptoms. If you do experience symptoms, they may include: […] Symptoms of chronic lymphocytic leukemia include enlarged lymph nodes in the groin, neck, stomach, or underarms, fatigue, fevers, frequent infections, night sweats, pain below the ribs on the left side (from an enlarged spleen), and weight loss. […] Chronic lymphocytic leukemia treatment may include targeted therapy, chemotherapy, radiation therapy, immunotherapy, stem cell transplant, and participation in clinical trials.

• #77 Chronic lymphocytic leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-lymphocytic-leukemia/symptoms-causes/syc-20352428

  Chronic lymphocytic leukemia most commonly affects older adults. […] Many people with chronic lymphocytic leukemia have no symptoms at first. Signs and symptoms might develop as the cancer progresses. They might include: […] Enlarged, but painless, lymph nodes […] Fatigue […] Fever […] Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen […] Night sweats […] Weight loss […] Frequent infections.

• #78 Chronic lymphocytic leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-lymphocytic-leukemia/symptoms-causes/syc-20352428

  Chronic lymphocytic leukemia most commonly affects older adults. […] Many people with chronic lymphocytic leukemia have no symptoms at first. Signs and symptoms might develop as the cancer progresses. They might include: […] Enlarged, but painless, lymph nodes […] Fatigue […] Fever […] Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen […] Night sweats […] Weight loss […] Frequent infections.

• #79 Chronic lymphocytic leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-lymphocytic-leukemia/symptoms-causes/syc-20352428

  Chronic lymphocytic leukemia most commonly affects older adults. […] Many people with chronic lymphocytic leukemia have no symptoms at first. Signs and symptoms might develop as the cancer progresses. They might include: […] Enlarged, but painless, lymph nodes […] Fatigue […] Fever […] Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen […] Night sweats […] Weight loss […] Frequent infections.

• #80 Chronic lymphocytic leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-lymphocytic-leukemia/symptoms-causes/syc-20352428

  Chronic lymphocytic leukemia most commonly affects older adults. […] Many people with chronic lymphocytic leukemia have no symptoms at first. Signs and symptoms might develop as the cancer progresses. They might include: […] Enlarged, but painless, lymph nodes […] Fatigue […] Fever […] Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen […] Night sweats […] Weight loss […] Frequent infections.

• #81 Chronic lymphocytic leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-lymphocytic-leukemia/symptoms-causes/syc-20352428

  Chronic lymphocytic leukemia most commonly affects older adults. […] Many people with chronic lymphocytic leukemia have no symptoms at first. Signs and symptoms might develop as the cancer progresses. They might include: […] Enlarged, but painless, lymph nodes […] Fatigue […] Fever […] Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen […] Night sweats […] Weight loss […] Frequent infections.

• #82 Chronic lymphocytic leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/chronic-lymphocytic-leukemia/symptoms-causes/syc-20352428

  Chronic lymphocytic leukemia most commonly affects older adults. […] Many people with chronic lymphocytic leukemia have no symptoms at first. Signs and symptoms might develop as the cancer progresses. They might include: […] Enlarged, but painless, lymph nodes […] Fatigue […] Fever […] Pain in the upper left portion of the abdomen, which may be caused by an enlarged spleen […] Night sweats […] Weight loss […] Frequent infections.

• #83 Symptoms of chronic lymphocytic leukaemia (CLL) | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/chronic-lymphocytic-leukaemia-cll/symptoms

  The extra white blood cells take up more space in the bone marrow as their numbers grow. So there is not enough room for platelets to be made. […] You might feel more tired than normal, even if you’re getting a good night’s sleep. This could be because you do not have enough red blood cells (anaemia). […] The lack of space in the bone marrow also interferes with the production of red blood cells. […] Some people whose CLL has changed (transformed) into a high grade disease have bone pain and night sweats. […] If you have any of these symptoms you must have them checked by your GP.

• #84 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Acute leukemia requires aggressive, timely treatment. Chronic leukemia involves more-mature blood cells. These blood cells replicate or accumulate more slowly and can function normally for a period of time. Some forms of chronic leukemia initially produce no early symptoms and can go unnoticed or undiagnosed for years. […] A person with CML may have few or no symptoms for months or years before entering a phase in which the leukemia cells grow more quickly.

• #85 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  Symptoms include: Weakness, Dizziness or lightheadedness, Shortness of breath, Fever, Recurring or chronic infections, Bruising easily, Blood clotting issues such as frequent or severe nosebleeds and bleeding gums. […] Symptoms include: Tiredness, Shortness of breath, Decreased appetite or feeling full without eating much, Night sweats, Unexplained weight loss, Enlarged spleen and/or lymph nodes, Recurring or chronic infections in areas such as the skin, lungs or kidneys. […] Symptoms include: Weakness, Fatigue, Unexplained weight loss, Night sweats and/or fever, Bone pain, Abdominal pain or sense of fullness, Enlarged spleen. […] Even though some leukemia symptoms, such as fever, vomiting, fatigue, aches and night sweats often resemble the cold, flu or other common illness, its important that you pay attention to them. If these symptoms dont go away at a normal pace (1-2 weeks), or you notice a combination of these symptoms at one time, Rocky Mountain Cancer Centers recommends that you make an appointment with your primary care physician who will likely start with some blood tests to see what may be the root cause.

• #86 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  Symptoms include: Weakness, Dizziness or lightheadedness, Shortness of breath, Fever, Recurring or chronic infections, Bruising easily, Blood clotting issues such as frequent or severe nosebleeds and bleeding gums. […] Symptoms include: Tiredness, Shortness of breath, Decreased appetite or feeling full without eating much, Night sweats, Unexplained weight loss, Enlarged spleen and/or lymph nodes, Recurring or chronic infections in areas such as the skin, lungs or kidneys. […] Symptoms include: Weakness, Fatigue, Unexplained weight loss, Night sweats and/or fever, Bone pain, Abdominal pain or sense of fullness, Enlarged spleen. […] Even though some leukemia symptoms, such as fever, vomiting, fatigue, aches and night sweats often resemble the cold, flu or other common illness, its important that you pay attention to them. If these symptoms dont go away at a normal pace (1-2 weeks), or you notice a combination of these symptoms at one time, Rocky Mountain Cancer Centers recommends that you make an appointment with your primary care physician who will likely start with some blood tests to see what may be the root cause.

• #87 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  Symptoms include: Weakness, Dizziness or lightheadedness, Shortness of breath, Fever, Recurring or chronic infections, Bruising easily, Blood clotting issues such as frequent or severe nosebleeds and bleeding gums. […] Symptoms include: Tiredness, Shortness of breath, Decreased appetite or feeling full without eating much, Night sweats, Unexplained weight loss, Enlarged spleen and/or lymph nodes, Recurring or chronic infections in areas such as the skin, lungs or kidneys. […] Symptoms include: Weakness, Fatigue, Unexplained weight loss, Night sweats and/or fever, Bone pain, Abdominal pain or sense of fullness, Enlarged spleen. […] Even though some leukemia symptoms, such as fever, vomiting, fatigue, aches and night sweats often resemble the cold, flu or other common illness, its important that you pay attention to them. If these symptoms dont go away at a normal pace (1-2 weeks), or you notice a combination of these symptoms at one time, Rocky Mountain Cancer Centers recommends that you make an appointment with your primary care physician who will likely start with some blood tests to see what may be the root cause.

• #88 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  Symptoms include: Weakness, Dizziness or lightheadedness, Shortness of breath, Fever, Recurring or chronic infections, Bruising easily, Blood clotting issues such as frequent or severe nosebleeds and bleeding gums. […] Symptoms include: Tiredness, Shortness of breath, Decreased appetite or feeling full without eating much, Night sweats, Unexplained weight loss, Enlarged spleen and/or lymph nodes, Recurring or chronic infections in areas such as the skin, lungs or kidneys. […] Symptoms include: Weakness, Fatigue, Unexplained weight loss, Night sweats and/or fever, Bone pain, Abdominal pain or sense of fullness, Enlarged spleen. […] Even though some leukemia symptoms, such as fever, vomiting, fatigue, aches and night sweats often resemble the cold, flu or other common illness, its important that you pay attention to them. If these symptoms dont go away at a normal pace (1-2 weeks), or you notice a combination of these symptoms at one time, Rocky Mountain Cancer Centers recommends that you make an appointment with your primary care physician who will likely start with some blood tests to see what may be the root cause.

• #89 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  Symptoms include: Weakness, Dizziness or lightheadedness, Shortness of breath, Fever, Recurring or chronic infections, Bruising easily, Blood clotting issues such as frequent or severe nosebleeds and bleeding gums. […] Symptoms include: Tiredness, Shortness of breath, Decreased appetite or feeling full without eating much, Night sweats, Unexplained weight loss, Enlarged spleen and/or lymph nodes, Recurring or chronic infections in areas such as the skin, lungs or kidneys. […] Symptoms include: Weakness, Fatigue, Unexplained weight loss, Night sweats and/or fever, Bone pain, Abdominal pain or sense of fullness, Enlarged spleen. […] Even though some leukemia symptoms, such as fever, vomiting, fatigue, aches and night sweats often resemble the cold, flu or other common illness, its important that you pay attention to them. If these symptoms dont go away at a normal pace (1-2 weeks), or you notice a combination of these symptoms at one time, Rocky Mountain Cancer Centers recommends that you make an appointment with your primary care physician who will likely start with some blood tests to see what may be the root cause.

• #90 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  Symptoms include: Weakness, Dizziness or lightheadedness, Shortness of breath, Fever, Recurring or chronic infections, Bruising easily, Blood clotting issues such as frequent or severe nosebleeds and bleeding gums. […] Symptoms include: Tiredness, Shortness of breath, Decreased appetite or feeling full without eating much, Night sweats, Unexplained weight loss, Enlarged spleen and/or lymph nodes, Recurring or chronic infections in areas such as the skin, lungs or kidneys. […] Symptoms include: Weakness, Fatigue, Unexplained weight loss, Night sweats and/or fever, Bone pain, Abdominal pain or sense of fullness, Enlarged spleen. […] Even though some leukemia symptoms, such as fever, vomiting, fatigue, aches and night sweats often resemble the cold, flu or other common illness, its important that you pay attention to them. If these symptoms dont go away at a normal pace (1-2 weeks), or you notice a combination of these symptoms at one time, Rocky Mountain Cancer Centers recommends that you make an appointment with your primary care physician who will likely start with some blood tests to see what may be the root cause.

• #91 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  Symptoms include: Weakness, Dizziness or lightheadedness, Shortness of breath, Fever, Recurring or chronic infections, Bruising easily, Blood clotting issues such as frequent or severe nosebleeds and bleeding gums. […] Symptoms include: Tiredness, Shortness of breath, Decreased appetite or feeling full without eating much, Night sweats, Unexplained weight loss, Enlarged spleen and/or lymph nodes, Recurring or chronic infections in areas such as the skin, lungs or kidneys. […] Symptoms include: Weakness, Fatigue, Unexplained weight loss, Night sweats and/or fever, Bone pain, Abdominal pain or sense of fullness, Enlarged spleen. […] Even though some leukemia symptoms, such as fever, vomiting, fatigue, aches and night sweats often resemble the cold, flu or other common illness, its important that you pay attention to them. If these symptoms dont go away at a normal pace (1-2 weeks), or you notice a combination of these symptoms at one time, Rocky Mountain Cancer Centers recommends that you make an appointment with your primary care physician who will likely start with some blood tests to see what may be the root cause.

• #92 Signs & Symptoms of Leukemia | Rocky Mountain Cancer Centers

  https://www.rockymountaincancercenters.com/leukemia/sign-symptoms-of-leukemia

  Symptoms include: Weakness, Dizziness or lightheadedness, Shortness of breath, Fever, Recurring or chronic infections, Bruising easily, Blood clotting issues such as frequent or severe nosebleeds and bleeding gums. […] Symptoms include: Tiredness, Shortness of breath, Decreased appetite or feeling full without eating much, Night sweats, Unexplained weight loss, Enlarged spleen and/or lymph nodes, Recurring or chronic infections in areas such as the skin, lungs or kidneys. […] Symptoms include: Weakness, Fatigue, Unexplained weight loss, Night sweats and/or fever, Bone pain, Abdominal pain or sense of fullness, Enlarged spleen. […] Even though some leukemia symptoms, such as fever, vomiting, fatigue, aches and night sweats often resemble the cold, flu or other common illness, its important that you pay attention to them. If these symptoms dont go away at a normal pace (1-2 weeks), or you notice a combination of these symptoms at one time, Rocky Mountain Cancer Centers recommends that you make an appointment with your primary care physician who will likely start with some blood tests to see what may be the root cause.

• #93 Leukemia Stages and Survival Rate

  https://www.cancercenter.com/cancer-types/leukemia/stages

  By identifying the stage of chronic lymphocytic leukemia, the care team may choose when to begin treatment and determine which CLL treatments to recommend. […] The Rai system of chronic lymphocytic leukemia staging is sometimes simplified into low risk (stage 0), medium risk (stage 1 and 2) and high risk (stage 3 and 4). The care team may use this classification to help determine when to begin treatment. […] In order to stage chronic myeloid leukemia (CML), the care team examines blood and bone marrow tests to determine the number of diseased cells. […] The majority of CML patients are diagnosed during this phase as a result of mild symptoms, particularly fatigue. […] If CML has not responded to treatment well during the chronic phase, it becomes more aggressive, which may lead to the accelerated phase. At this point, symptoms may become more noticeable. […] This is the most aggressive stage of chronic myeloid leukemia. Blastic refers to having more than 20 percent myeloblasts or lymphoblasts. Symptoms are similar to those of acute myeloid leukemia.

• #94 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #95 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  Having too many leukemia cells and too few normal cells is harmful for several reasons: Leukemia cells serve no purpose in keeping you healthy. Normal blood cells have very little space and support to mature and multiply inside of your bone marrow because the leukemia cells overtake them. Fewer red blood cells, healthy white blood cells and platelets are made and released into your blood. As a result, your bodys organs and tissues wont get the oxygen needed to work properly. Also, your body wont be able to fight infections or form blood clots when needed. […] If you have acute leukemia, youll feel sick within weeks of the leukemia cells forming. Acute leukemia is life-threatening and requires immediate initiation of therapy. […] If you have chronic leukemia, you may not have noticeable symptoms for years.

• #96 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #97 Leukemia Symptoms and Signs

  https://www.webmd.com/cancer/lymphoma/understanding-leukemia-symptoms

  Your symptoms may become more distressing in the advanced stages of leukemia. They may include: Taking slow breaths with long pauses in between, Stuffy nose and noisy breathing, Mouth and lip dryness, Restlessness, Hallucinations and dream-like experiences, Cool-to-touch skin that turns bluish or dusky, Passing less urine, Loss of bladder and bowel control, Confusion about people, time, and place, Loss of consciousness and responsiveness […] Leukemia may also cause symptoms that involve your skin, including: Pale skin, Red, brown, or purplish spots in your skin that may be called leukemia rash or leukemia red spots, Skin bruises, Easily bleeding, Lumps under the skin […] Anemia is when a person has lower-than-normal levels of healthy red blood cells. It often happens in people with leukemia because cancer cells multiply very quickly, limiting how many red blood cells the body produces. Anemia may contribute to death in people with leukemia. If you have leukemia, you may also have anemia symptoms such as: Tiredness, Weakness, Feeling cold, Difficulty breathing, Dizziness or lightheadedness, Headaches, Pale skin

• #98 Symptoms of chronic lymphocytic leukaemia (CLL) | Cancer Research UK

  https://www.cancerresearchuk.org/about-cancer/chronic-lymphocytic-leukaemia-cll/symptoms

  The extra white blood cells take up more space in the bone marrow as their numbers grow. So there is not enough room for platelets to be made. […] You might feel more tired than normal, even if you’re getting a good night’s sleep. This could be because you do not have enough red blood cells (anaemia). […] The lack of space in the bone marrow also interferes with the production of red blood cells. […] Some people whose CLL has changed (transformed) into a high grade disease have bone pain and night sweats. […] If you have any of these symptoms you must have them checked by your GP.

• #99 Azthena logo with the word Azthena

  https://www.news-medical.net/health/Acute-Lymphoblastic-Leukemia-Symptoms.aspx

  Acute lymphoblastic leukemia most commonly affects children below 15 years of age. It is rare among adults. The symptoms are usually slow in onset but may rapidly get severe as the number of immature white blood cells (blast cells) rises and overcrowd other cells in the blood. […] The symptoms of ALL are indicative of the underlying pathology of the cancer. The symptoms of ALL include:- Pallor the skin and mucus membranes are pale. This is the hallmark sign of anemia. Due to the rise in number of blast cells in blood the red blood cells are lowered in number and this may result in anemia. […] Tiredness and fatigue are symptoms that are associated with anemia and are seen commonly in ALL patients. […] There may be breathlessness, palpitations and easy fatigability due to anemia and inadequate oxygenation.

• #100 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  The most common signs and symptoms of acute myelogenous leukemia in children are: […] Anemia occurs when normal red blood cells can’t be produced because the bone marrow is overcrowded by leukemia cells. The anemic child may be more tired, take more naps, look pale, and her heart may be racing. The number of red blood cells on a blood count (expressed as „hemoglobin” or „hematocrit”) will be below normal. […] When the bone marrow cannot produce enough platelets, bleeding can occur, especially when the platelet numbers are less than 10-20,000/mm3. Low platelets can cause a child to bruise or bleed more easily. […] Pain in bones and joints is usually a result of the bone marrow being crowded with leukemic blasts. This is often mistaken for „growing pains.” […] The child with leukemia often shows non-specific symptoms of infection such as fever and fatigue. Although the blood count of a child with leukemia may show a high number of white blood cells, these cells are immature and do not normally fight infection. As a result, the child may have difficulty recovering from an ordinary childhood infection or may develop unusual infections.

• #101 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  The most common signs and symptoms of acute myelogenous leukemia in children are: […] Anemia occurs when normal red blood cells can’t be produced because the bone marrow is overcrowded by leukemia cells. The anemic child may be more tired, take more naps, look pale, and her heart may be racing. The number of red blood cells on a blood count (expressed as „hemoglobin” or „hematocrit”) will be below normal. […] When the bone marrow cannot produce enough platelets, bleeding can occur, especially when the platelet numbers are less than 10-20,000/mm3. Low platelets can cause a child to bruise or bleed more easily. […] Pain in bones and joints is usually a result of the bone marrow being crowded with leukemic blasts. This is often mistaken for „growing pains.” […] The child with leukemia often shows non-specific symptoms of infection such as fever and fatigue. Although the blood count of a child with leukemia may show a high number of white blood cells, these cells are immature and do not normally fight infection. As a result, the child may have difficulty recovering from an ordinary childhood infection or may develop unusual infections.

• #102 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #103 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #104 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  A shortage of blood platelets is called thrombocytopenia. This can lead to: Bruises (or small red or purple spots) on the skin, Excess bleeding, Frequent or severe nosebleeds, Bleeding gums, Heavy periods (menstrual bleeding) in women. […] The cancer cells in AML (called blasts) are bigger than normal blood cells and have more trouble traveling through tiny blood vessels. If the blast count gets very high, these cells can clog up blood vessels and make it hard for normal red blood cells (and oxygen) to get to tissues. This is called leukostasis. […] People with a certain type of AML called acute promyelocytic leukemia (APL) might have problems with bleeding and blood clotting. […] Some people with AML have bone pain or joint pain caused by the buildup of leukemia cells in these areas.

• #105 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Signs and symptoms are changes in the body that may indicate disease. A person who has signs or symptoms that suggest the possibility of leukemia is usually referred to a specialist. It is common for someone with ALL to feel a loss of well-being because of the underproduction of normal blood cells. Consequently, patients with ALL do not have sufficient numbers of mature red blood cells, white blood cells and platelets. […] Symptoms of anemia (low red blood cell count) include fatigue, shortness of breath during normal physical activities, dizziness, and pale complexion. […] Symptoms of neutropenia (low number of neutrophils, a type of white blood cells) include frequent infections and fever. […] Symptoms of thrombocytopenia (low platelet count) include bruising easily, prolonged bleeding from minor cuts, the appearance of pinhead-sized red spots on the skin, called petechiae, frequent or severe nosebleeds, bleeding gums, and heavier or more frequent menstrual periods.

• #106 Hairy Cell Leukemia: Symptoms, Causes & Treatment

  https://my.clevelandclinic.org/health/diseases/23177-hairy-cell-leukemia

  Unusual bruising or bleeding: Hairy cell leukemia keeps your bone marrow from making enough platelets, which helps slow or stop bleeding. […] This condition increases your risk of infections because you have very low levels of infection-fighting white blood cells. These include bacterial infections, viral infections or fungal infections that may be life-threatening. […] Theres no cure for hairy cell leukemia. Research shows treatment, including chemotherapy, can put this condition into remission for 10 years or more. Remission means you dont have symptoms anymore and tests dont find any signs of the condition. […] That said, hairy cell leukemia can come back after several years of initial treatment. But there are treatments to put the disease back into remission.

• #107 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Signs and symptoms are changes in the body that may indicate disease. A person who has signs or symptoms that suggest the possibility of leukemia is usually referred to a specialist. It is common for someone with ALL to feel a loss of well-being because of the underproduction of normal blood cells. Consequently, patients with ALL do not have sufficient numbers of mature red blood cells, white blood cells and platelets. […] Symptoms of anemia (low red blood cell count) include fatigue, shortness of breath during normal physical activities, dizziness, and pale complexion. […] Symptoms of neutropenia (low number of neutrophils, a type of white blood cells) include frequent infections and fever. […] Symptoms of thrombocytopenia (low platelet count) include bruising easily, prolonged bleeding from minor cuts, the appearance of pinhead-sized red spots on the skin, called petechiae, frequent or severe nosebleeds, bleeding gums, and heavier or more frequent menstrual periods.

• #108 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #109 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Signs and symptoms are changes in the body that may indicate disease. A person who has signs or symptoms that suggest the possibility of leukemia is usually referred to a specialist. It is common for someone with ALL to feel a loss of well-being because of the underproduction of normal blood cells. Consequently, patients with ALL do not have sufficient numbers of mature red blood cells, white blood cells and platelets. […] Symptoms of anemia (low red blood cell count) include fatigue, shortness of breath during normal physical activities, dizziness, and pale complexion. […] Symptoms of neutropenia (low number of neutrophils, a type of white blood cells) include frequent infections and fever. […] Symptoms of thrombocytopenia (low platelet count) include bruising easily, prolonged bleeding from minor cuts, the appearance of pinhead-sized red spots on the skin, called petechiae, frequent or severe nosebleeds, bleeding gums, and heavier or more frequent menstrual periods.

• #110 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Signs and symptoms are changes in the body that may indicate disease. A person who has signs or symptoms that suggest the possibility of leukemia is usually referred to a specialist. It is common for someone with ALL to feel a loss of well-being because of the underproduction of normal blood cells. Consequently, patients with ALL do not have sufficient numbers of mature red blood cells, white blood cells and platelets. […] Symptoms of anemia (low red blood cell count) include fatigue, shortness of breath during normal physical activities, dizziness, and pale complexion. […] Symptoms of neutropenia (low number of neutrophils, a type of white blood cells) include frequent infections and fever. […] Symptoms of thrombocytopenia (low platelet count) include bruising easily, prolonged bleeding from minor cuts, the appearance of pinhead-sized red spots on the skin, called petechiae, frequent or severe nosebleeds, bleeding gums, and heavier or more frequent menstrual periods.

• #111 Leukemia Symptoms | Learn The Signs Of Leukemia | LLS

  https://www.lls.org/leukemia/acute-lymphoblastic-leukemia/signs-and-symptoms

  Signs and symptoms are changes in the body that may indicate disease. A person who has signs or symptoms that suggest the possibility of leukemia is usually referred to a specialist. It is common for someone with ALL to feel a loss of well-being because of the underproduction of normal blood cells. Consequently, patients with ALL do not have sufficient numbers of mature red blood cells, white blood cells and platelets. […] Symptoms of anemia (low red blood cell count) include fatigue, shortness of breath during normal physical activities, dizziness, and pale complexion. […] Symptoms of neutropenia (low number of neutrophils, a type of white blood cells) include frequent infections and fever. […] Symptoms of thrombocytopenia (low platelet count) include bruising easily, prolonged bleeding from minor cuts, the appearance of pinhead-sized red spots on the skin, called petechiae, frequent or severe nosebleeds, bleeding gums, and heavier or more frequent menstrual periods.

• #112 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #113 Leukemia – Wikipedia

  https://en.wikipedia.org/wiki/Leukemia

  Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. […] These symptoms occur due to a lack of normal blood cells. […] Damage to the bone marrow, by way of displacing the normal bone marrow cells with higher numbers of immature white blood cells, results in a lack of blood platelets, which are important in the blood clotting process. This means people with leukemia may easily become bruised, bleed excessively, or develop pinprick bleeds (petechiae). […] White blood cells, which are involved in fighting pathogens, may be suppressed or dysfunctional. This could cause the person’s immune system to be unable to fight off a simple infection or to start attacking other body cells. […] Because leukemia prevents the immune system from working normally, some people experience frequent infection, ranging from infected tonsils, sores in the mouth, or diarrhea to life-threatening pneumonia or opportunistic infections.

• #114 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Acute myeloid leukemia (AML) can cause many different signs and symptoms. Some are more common with certain subtypes of AML. […] People with acute myeloid leukemia often have several non-specific (general) symptoms. These can include: Weight loss, Fatigue, Fever, Night sweats, Loss of appetite. […] Many signs and symptoms of AML are the result of low levels of normal blood cells. This happens when the leukemia cells crowd out the normal blood-making cells in the bone marrow. As a result, people don’t have enough normal red blood cells, white blood cells, and blood platelets. […] A shortage of red blood cells is called anemia. Anemia can cause: Tiredness (fatigue), Weakness, Feeling cold, Feeling dizzy or lightheaded, Headaches, Pale skin, Shortness of breath. […] Infections can develop because of a shortage of normal white blood cells (leukopenia), specifically a shortage of infection-fighting white blood cells called neutrophils (a condition called neutropenia). People with AML can get infections that don’t go away, or they may get one infection after another.

• #115 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  The most common signs and symptoms of acute myelogenous leukemia in children are: […] Anemia occurs when normal red blood cells can’t be produced because the bone marrow is overcrowded by leukemia cells. The anemic child may be more tired, take more naps, look pale, and her heart may be racing. The number of red blood cells on a blood count (expressed as „hemoglobin” or „hematocrit”) will be below normal. […] When the bone marrow cannot produce enough platelets, bleeding can occur, especially when the platelet numbers are less than 10-20,000/mm3. Low platelets can cause a child to bruise or bleed more easily. […] Pain in bones and joints is usually a result of the bone marrow being crowded with leukemic blasts. This is often mistaken for „growing pains.” […] The child with leukemia often shows non-specific symptoms of infection such as fever and fatigue. Although the blood count of a child with leukemia may show a high number of white blood cells, these cells are immature and do not normally fight infection. As a result, the child may have difficulty recovering from an ordinary childhood infection or may develop unusual infections.

• #116 Leukemia – Wikipedia

  https://en.wikipedia.org/wiki/Leukemia

  Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. […] These symptoms occur due to a lack of normal blood cells. […] Damage to the bone marrow, by way of displacing the normal bone marrow cells with higher numbers of immature white blood cells, results in a lack of blood platelets, which are important in the blood clotting process. This means people with leukemia may easily become bruised, bleed excessively, or develop pinprick bleeds (petechiae). […] White blood cells, which are involved in fighting pathogens, may be suppressed or dysfunctional. This could cause the person’s immune system to be unable to fight off a simple infection or to start attacking other body cells. […] Because leukemia prevents the immune system from working normally, some people experience frequent infection, ranging from infected tonsils, sores in the mouth, or diarrhea to life-threatening pneumonia or opportunistic infections.

• #117 Symptoms of leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/leukemia/signs-and-symptoms

  The signs or symptoms of leukemia may vary depending on whether you have an acute or chronic type of leukemia. […] Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. […] Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test. […] Other health conditions can cause the same symptoms as leukemia. […] Fatigue, a general feeling of discomfort or illness (called malaise), loss of appetite, weight loss, fever, shortness of breath, paleness, rapid heartbeat (called palpitations), weakness, dizziness, easy bruising, frequent or severe nose bleeds, bleeding gums, bleeding in the middle of a menstrual cycle or heavy menstrual flow, tiny, flat, red spots caused by bleeding just under the surface of the skin (called petechiae), frequent infections in the lungs, urinary tract or gums or around the anus, frequent cold sores, vomiting, headache, sore throat, night sweats, bone or joint pain, enlarged lymph nodes in the neck, underarm, groin or above the collarbone, abdominal discomfort or feeling of fullness, vision problems, sores in the eyes, swelling of the testicles, chloroma a collection of leukemia cells, or blasts, under the skin or in other parts of the body, leukemia cutis appears as sores or as patches of any size that are usually pink or tan in colour, leukocytoclastic vasculitis a condition that looks like an allergic reaction on the skin and usually causes sores on the hands and feet, Sweets syndrome, or acute febrile neutrophilic dermatosis causes fever and painful sores that may appear anywhere on the body.

• #118 Symptoms of leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/leukemia/signs-and-symptoms

  The signs or symptoms of leukemia may vary depending on whether you have an acute or chronic type of leukemia. […] Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. […] Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test. […] Other health conditions can cause the same symptoms as leukemia. […] Fatigue, a general feeling of discomfort or illness (called malaise), loss of appetite, weight loss, fever, shortness of breath, paleness, rapid heartbeat (called palpitations), weakness, dizziness, easy bruising, frequent or severe nose bleeds, bleeding gums, bleeding in the middle of a menstrual cycle or heavy menstrual flow, tiny, flat, red spots caused by bleeding just under the surface of the skin (called petechiae), frequent infections in the lungs, urinary tract or gums or around the anus, frequent cold sores, vomiting, headache, sore throat, night sweats, bone or joint pain, enlarged lymph nodes in the neck, underarm, groin or above the collarbone, abdominal discomfort or feeling of fullness, vision problems, sores in the eyes, swelling of the testicles, chloroma a collection of leukemia cells, or blasts, under the skin or in other parts of the body, leukemia cutis appears as sores or as patches of any size that are usually pink or tan in colour, leukocytoclastic vasculitis a condition that looks like an allergic reaction on the skin and usually causes sores on the hands and feet, Sweets syndrome, or acute febrile neutrophilic dermatosis causes fever and painful sores that may appear anywhere on the body.

• #119 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #120 Leukemia: Symptoms, Signs, Causes, Types, and More

  https://www.healthline.com/health/leukemia

  Leukemia can refer to all cancers affecting the white blood cells. How the cancer spreads can depend on the type of leukemia and how aggressive it is. […] In leukemia, the WBCs do not function like normal WBCs. They divide too quickly and eventually crowd out normal blood cells. […] The symptoms of leukemia may include: excessive sweating, especially at night (night sweats), fatigue and weakness that do not go away with rest, unintentional weight loss, bone pain and tenderness, painless, swollen lymph nodes, especially in the neck and armpits, enlarged liver or spleen, red spots on the skin, called petechiae, bleeding easily and bruising easily, fever or chills, frequent infections. […] How the cancer spreads depends on the type of leukemia and how aggressive it is. Parts of your body that leukemia can spread to include the lungs, gastrointestinal tract, heart, kidneys, testicles. […] Acute myeloid leukemia (AML) is the most aggressive type of leukemia. It progresses rapidly and requires immediate treatment.

• #121 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This might be noticed as a fullness or swelling of the belly, or feeling full after eating only a small amount. […] ALL that has spread to lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin, or in underarm areas), might be noticed as lumps under the skin. […] Sometimes leukemia cells build up near the surface of the bone or inside the joint, which can lead to bone or joint pain. […] If ALL spreads to the brain and spinal cord it can cause headaches, weakness, seizures, vomiting, trouble with balance, facial muscle weakness or numbness, or blurred vision. […] The T-cell subtype of ALL often affects the thymus, which is a small organ in the middle of the chest behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus can press on the trachea, which can lead to coughing or trouble breathing.

• #122 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Swollen lymph nodes. These are enlarged lumps that can be seen or felt underneath the skin usually in the armpit, neck or groin area. Often, they can be the result of an everyday infection or allergy. However, they might be a sign of leukaemia, particularly if they are painless, last longer than two weeks, are hard or unmovable, or grow in size. […] Swollen and/or painful stomach. This can include a sharp pain or swelling in the stomach and constantly feeling full. […] Infections. Factors such as the duration and frequency of infections can help determine if they are a sign of leukaemia. Specific signs include a cough, fever or chest infection that is recurring or long lasting; and small cuts to your skin becoming infected more frequently. […] Night sweats. The temperature at which night sweats occur, and the quantity of sweat lost can help determine if a persons night sweats are a symptom of leukaemia. If night sweats are regular, drench you in sweat, or occur in cool environments its worth visiting your GP.

• #123 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This might be noticed as a fullness or swelling of the belly, or feeling full after eating only a small amount. […] ALL that has spread to lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin, or in underarm areas), might be noticed as lumps under the skin. […] Sometimes leukemia cells build up near the surface of the bone or inside the joint, which can lead to bone or joint pain. […] If ALL spreads to the brain and spinal cord it can cause headaches, weakness, seizures, vomiting, trouble with balance, facial muscle weakness or numbness, or blurred vision. […] The T-cell subtype of ALL often affects the thymus, which is a small organ in the middle of the chest behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus can press on the trachea, which can lead to coughing or trouble breathing.

• #124 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This might be noticed as a fullness or swelling of the belly, or feeling full after eating only a small amount. […] ALL that has spread to lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin, or in underarm areas), might be noticed as lumps under the skin. […] Sometimes leukemia cells build up near the surface of the bone or inside the joint, which can lead to bone or joint pain. […] If ALL spreads to the brain and spinal cord it can cause headaches, weakness, seizures, vomiting, trouble with balance, facial muscle weakness or numbness, or blurred vision. […] The T-cell subtype of ALL often affects the thymus, which is a small organ in the middle of the chest behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus can press on the trachea, which can lead to coughing or trouble breathing.

• #125 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  Leukemia cells can collect in the kidneys, liver, and spleen, causing enlargement of these organs which can cause pain in the abdomen. This pain may lead to loss of appetite and weight loss. […] Lymph nodes filter the blood. Leukemia cells often collect in the nodes, causing swelling. Swelling occurs in lymph nodes in the neck, under the arms, in the groin, and chest. Sometimes it is difficult to distinguish the lymph nodes of leukemia from those that are a normal part of the body’s response to infection or allergy. […] In leukemia, cells can clump together in the thymus a gland under the breastbone and around the throat. This mass of cells can cause difficulty breathing. Any wheezing, coughing, and/or labored or painful breathing requires immediate medical attention.

• #126 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  Leukemia cells can collect in the kidneys, liver, and spleen, causing enlargement of these organs which can cause pain in the abdomen. This pain may lead to loss of appetite and weight loss. […] Lymph nodes filter the blood. Leukemia cells often collect in the nodes, causing swelling. Swelling occurs in lymph nodes in the neck, under the arms, in the groin, and chest. Sometimes it is difficult to distinguish the lymph nodes of leukemia from those that are a normal part of the body’s response to infection or allergy. […] In leukemia, cells can clump together in the thymus a gland under the breastbone and around the throat. This mass of cells can cause difficulty breathing. Any wheezing, coughing, and/or labored or painful breathing requires immediate medical attention.

• #127 Leukemia symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/leukaemia-symptoms-signs/

  Infections that are more frequent, severe, or last longer, are a common symptom of leukemia. […] Leukemia can cause anaemia. […] Leukemia can affect your platelets (cells that help your blood to clot). […] You may have: increased sweating, particularly at night, drenching night sweats. […] Leukemia cells can build up in your spleen or liver, causing swelling or an enlarged spleen. […] Leukemia cells can build up in the bone marrow (the soft, spongy material inside some of our bones). […] Leukemia can sometimes cause blood clots to develop. […] Acute myeloid leukaemia (AML) or acute lymphoblastic leukaemia (ALL) can develop very quickly into leukostasis or blast crisis. […] A rare symptom of acute myeloid leukaemia (AML) is a chloroma.

• #128 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This might be noticed as a fullness or swelling of the belly, or feeling full after eating only a small amount. […] ALL that has spread to lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin, or in underarm areas), might be noticed as lumps under the skin. […] Sometimes leukemia cells build up near the surface of the bone or inside the joint, which can lead to bone or joint pain. […] If ALL spreads to the brain and spinal cord it can cause headaches, weakness, seizures, vomiting, trouble with balance, facial muscle weakness or numbness, or blurred vision. […] The T-cell subtype of ALL often affects the thymus, which is a small organ in the middle of the chest behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus can press on the trachea, which can lead to coughing or trouble breathing.

• #129 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #130 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This might be noticed as a fullness or swelling of the belly, or feeling full after eating only a small amount. […] ALL that has spread to lymph nodes close to the surface of the body (such as on the sides of the neck, in the groin, or in underarm areas), might be noticed as lumps under the skin. […] Sometimes leukemia cells build up near the surface of the bone or inside the joint, which can lead to bone or joint pain. […] If ALL spreads to the brain and spinal cord it can cause headaches, weakness, seizures, vomiting, trouble with balance, facial muscle weakness or numbness, or blurred vision. […] The T-cell subtype of ALL often affects the thymus, which is a small organ in the middle of the chest behind the sternum (breastbone) and in front of the trachea (windpipe). An enlarged thymus can press on the trachea, which can lead to coughing or trouble breathing.

• #131 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #132 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #133 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #134 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #135 Signs and Symptoms of Acute Myeloid Leukemia (AML) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-myeloid-leukemia/detection-diagnosis-staging/signs-symptoms.html

  Leukemia cells may build up in the liver and spleen, making them larger. This may be noticed as a fullness or swelling of the belly. […] If leukemia cells spread to the skin, they can cause lumps or spots that may look like common rashes. […] Certain types of AML may spread to the gums, causing swelling, pain, and bleeding. […] Spread to the brain and spinal cord can cause symptoms such as: Headaches, Weakness, Seizures, Vomiting, Trouble with balance, Facial numbness, Blurred vision. […] Rarely, AML can spread to lymph nodes and make them bigger.

• #136 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  If the thymus is enlarged, it may press on the SVC, causing the blood to back up in the veins. This is known as SVC syndrome. It can cause: Swelling in the face, neck, arms, and upper chest (sometimes with a bluish-red color), Headaches, Dizziness, Change in consciousness if it affects the brain. […] The SVC syndrome can be life-threatening, and needs to be treated right away.

• #137 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #138 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Pain in bones/joints. This can be a sharp pain or a constant dull ache in one or more bones. Bone pain caused by leukaemia is usually felt in the arms and legs, or in the ribs and sternum of the rib cage. Joint pain in ankles or wrists and swelling of large joints like the hips and shoulders can also be experienced. […] Shortness of breath. Symptoms of leukaemia can include breathlessness that comes on suddenly or during activities that would normally be effortless for the person, breathlessness lasting longer than a month, breathlessness that worsens over time and coughing lasting three weeks or more. […] Skin rashes. Skin rashes are likely to be unexplained and often have the appearance of small red and purple spots on the skin. […] Leukaemia symptoms in adults and children are very similar, however, symptoms in children can develop more quickly. The National Institute for Health and Care Excellence (NICE) recommends children be offered a very urgent blood count due to the acute nature of leukaemia in children. […] If you are experiencing any of these symptoms and you are concerned about blood cancer, please make sure to book an appointment with your GP. The faster leukaemia patients are diagnosed, the increased likelihood they will make a full recovery.

• #139 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Pain in bones/joints. This can be a sharp pain or a constant dull ache in one or more bones. Bone pain caused by leukaemia is usually felt in the arms and legs, or in the ribs and sternum of the rib cage. Joint pain in ankles or wrists and swelling of large joints like the hips and shoulders can also be experienced. […] Shortness of breath. Symptoms of leukaemia can include breathlessness that comes on suddenly or during activities that would normally be effortless for the person, breathlessness lasting longer than a month, breathlessness that worsens over time and coughing lasting three weeks or more. […] Skin rashes. Skin rashes are likely to be unexplained and often have the appearance of small red and purple spots on the skin. […] Leukaemia symptoms in adults and children are very similar, however, symptoms in children can develop more quickly. The National Institute for Health and Care Excellence (NICE) recommends children be offered a very urgent blood count due to the acute nature of leukaemia in children. […] If you are experiencing any of these symptoms and you are concerned about blood cancer, please make sure to book an appointment with your GP. The faster leukaemia patients are diagnosed, the increased likelihood they will make a full recovery.

• #140 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Pain in bones/joints. This can be a sharp pain or a constant dull ache in one or more bones. Bone pain caused by leukaemia is usually felt in the arms and legs, or in the ribs and sternum of the rib cage. Joint pain in ankles or wrists and swelling of large joints like the hips and shoulders can also be experienced. […] Shortness of breath. Symptoms of leukaemia can include breathlessness that comes on suddenly or during activities that would normally be effortless for the person, breathlessness lasting longer than a month, breathlessness that worsens over time and coughing lasting three weeks or more. […] Skin rashes. Skin rashes are likely to be unexplained and often have the appearance of small red and purple spots on the skin. […] Leukaemia symptoms in adults and children are very similar, however, symptoms in children can develop more quickly. The National Institute for Health and Care Excellence (NICE) recommends children be offered a very urgent blood count due to the acute nature of leukaemia in children. […] If you are experiencing any of these symptoms and you are concerned about blood cancer, please make sure to book an appointment with your GP. The faster leukaemia patients are diagnosed, the increased likelihood they will make a full recovery.

• #141 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #142 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Pain in bones/joints. This can be a sharp pain or a constant dull ache in one or more bones. Bone pain caused by leukaemia is usually felt in the arms and legs, or in the ribs and sternum of the rib cage. Joint pain in ankles or wrists and swelling of large joints like the hips and shoulders can also be experienced. […] Shortness of breath. Symptoms of leukaemia can include breathlessness that comes on suddenly or during activities that would normally be effortless for the person, breathlessness lasting longer than a month, breathlessness that worsens over time and coughing lasting three weeks or more. […] Skin rashes. Skin rashes are likely to be unexplained and often have the appearance of small red and purple spots on the skin. […] Leukaemia symptoms in adults and children are very similar, however, symptoms in children can develop more quickly. The National Institute for Health and Care Excellence (NICE) recommends children be offered a very urgent blood count due to the acute nature of leukaemia in children. […] If you are experiencing any of these symptoms and you are concerned about blood cancer, please make sure to book an appointment with your GP. The faster leukaemia patients are diagnosed, the increased likelihood they will make a full recovery.

• #143 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #144 Last Stages of Leukemia | ITC

  https://www.immunitytherapycenter.com/blog/end-stage-leukemia/

  Facing end-stage leukemia can be an overwhelming and challenging experience, both for individuals diagnosed with the disease and their loved ones. This article will provide a comprehensive guide to the symptoms of end-stage leukemia. […] End-stage leukemia is the final stage before end of life, where the disease has advanced significantly and poses significant physical and emotional challenges. […] During the latter stages of leukemia, symptoms categorized as physical, psychological, and emotional are often experienced, with the severity and how quickly each manifests often varying. […] According to UCHealth, common terminal leukemia symptoms include fatigue, easy bruising or bleeding, frequent infections, and bone and joint pain. […] In the later stages of leukemia, individuals may experience overwhelming tiredness and a lack of energy that persists even with rest.

• #145 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #146 Last Stages of Leukemia | ITC

  https://www.immunitytherapycenter.com/blog/end-stage-leukemia/

  Leukemia also leads to a weaker immune system, which can make one more susceptible to recurrent infections that ultimately become harder to treat. […] Unintentional weight loss is another common symptom in the advanced stages of leukemia due to loss of appetite, decreased physical function, and side effects from treatments. […] According to the Leukemia and Lymphoma Society, along with being felt in the long bones of the arms and legs, the bone pain caused by leukemia can also be felt in the ribs and in the breastbone. […] Seeking immediate medical attention is crucial if chest pain or difficulty breathing occurs to determine the underlying cause and receive appropriate care. […] Terminal leukemia refers to the phase when treatment options become limited, and end life care focuses on symptom management.

• #147 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #148 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #149 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #150 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #151 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #152 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #153 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #154 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #155 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #156 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #157 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #158 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #159 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #160 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #161 Leukemia Symptoms: Early Stage, Late Stage, Management Tips

  https://www.healthline.com/health/leukemia/leukemia-symptoms

  As leukemia advances, you may develop new or more severe symptoms as your blood cell counts continue to drop. Potential symptoms include: frequent infections, such as: chronic respiratory infections, digestive tract infections, skin infections, severe anemia, which might cause: headaches, irritability, loss of appetite, numbness and tingling in your hands and feet, weakness, severe fatigue, paleness, dizziness and lightheadedness, more severe bleeding and bruising, flat red spots on your skin (petechiae), rashes, swollen abdomen, other cancers, bone or joint pain, swollen lymph nodes. […] Symptoms of end stage leukemia can vary from person to person depending on the course of the disease and the leukemia subtype. Some people might develop severe disease after months, while others might not have severe symptoms for decades. End stage symptoms can potentially include: extreme tiredness and weakness, a need to rest or sleep all the time, extreme weight loss and loss of appetite, difficulty eating or drinking, changes in taste, trouble speaking, loss of ability to perform daily tasks, difficulty waking from sleep, hallucinations, low blood pressure, irregular heart rate, weak pulse, dark, bluish, or pale skin, loss of ability to regulate your bladder and bowels, loss of consciousness. […] Most leukemia symptoms develop due to cancer cells crowding out healthy platelets, red blood cells, and white blood cells. Common symptoms include tiredness, frequent infections, and easy bleeding or bruising.

• #162 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] Patients may also experience swelling and pain in the bones and joints due to the bone marrow becoming crowded with cancerous cells. Some patients may experience shortness of breath or breathing difficulties. Towards the final days, breathing may become irregular or louder.

• #163 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #164 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #165 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #166 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #167 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #168 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #169 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  If AML spreads to the liver, it may not function properly. This can lead to several symptoms, including: Nausea, Decreased appetite, Weight loss, Swelling and discomfort in the abdomen, Fluctuating blood sugar levels, Yellowing of eyes and skin (jaundice), Increased risk of bleeding, Lower level of consciousness. […] As AML progresses towards the final stages, patients may experience constant coldness, paleness, fatigue, and drowsiness. They may also begin to lose control of their bladder and bowel function. […] The progression of AML itself can cause death due to multiple organ failure. Additionally, complications related to disease progression, such as infections, bleeding, and thrombotic events, such as heart attacks and strokes, may cause death. Treatment complications can also cause death in some patients. […] AML can progress rapidly and may spread to other areas of the body. […] As AML progresses, symptoms may worsen or change. […] AML can cause death due to organ failure, infection, bleeding, or thrombotic events.

• #170 AML Late Stages: Spread, Symptoms & Care – HealthTree for Acute Myeloid Leukemia

  https://healthtree.org/aml/community/articles/aml-late-stages-symptoms-care

  Acute myeloid leukemia (AML) begins in the bone marrow and initially may cause flu-like symptoms. As abnormal white blood cells (cancerous cells) build up, these symptoms can change or worsen. As AML is an aggressive form of cancer, it can progress rapidly. […] As AML progresses towards the final stages, symptoms may become more severe. Body functions may slow down, and complications may arise. Cancerous cells multiply, which may prevent the bone marrow from making new blood cells. This can cause: Anemia, Bleeding, An increased risk of infection. […] Patients may also experience swelling and pain in the bones and joints due to the bone marrow becoming crowded with cancerous cells. Some patients may experience shortness of breath or breathing difficulties. Towards the final days, breathing may become irregular or louder.

• #171 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Acute leukemia requires aggressive, timely treatment. Chronic leukemia involves more-mature blood cells. These blood cells replicate or accumulate more slowly and can function normally for a period of time. Some forms of chronic leukemia initially produce no early symptoms and can go unnoticed or undiagnosed for years. […] A person with CML may have few or no symptoms for months or years before entering a phase in which the leukemia cells grow more quickly.

• #172 Leukemia Treatment & Diagnosis | University of Kansas Cancer Center

  https://www.kucancercenter.org/cancer/cancer-types/leukemia

  Leukemia symptoms vary by the type of leukemia, but commonly include: Fever or chills, Persistent tiredness, Weakness or fatigue, Regular or serious infections, Unusual weight loss, Bruising or bleeding easily, Frequent nosebleeds, Night sweats or excessive sweating, Swollen lymph nodes, Pain or tenderness in your bones, Enlarged spleen or liver, Petechiae (small red spots on your skin). […] Acute leukemia develops quickly and makes you feel sick right away. Chronic leukemia moves slowly and may not cause symptoms for months or even years. […] Blood tests can check for high levels of white blood cells. […] During a physical exam, your doctor will look for signs of leukemia, such as swollen lymph nodes and an enlarged spleen or liver. […] AML is a blood cancer, which means that it comes from the cells in the bone marrow. Normal bone marrow makes all of the healthy red blood cells and infection fighting cells that you need for your body to function. But in the case of leukemia, the cancer cells replace those normal bone marrow cells. So people develop symptoms rather quickly of anemia, such as shortness of breath, or fatigue. They can develop infections, or they can even develop bleeding. And that’s why it’s such a medical emergency for us to diagnose it and get treatment started quickly.

• #173 LLS | Stages of Leukemia

  https://lls.org/blog/stages-leukemia-understanding-classification-and-progression

  Staging is a method used to describe or classify cancer based on how much of it is present in the body. […] However, leukemia a type of blood cancer does not typically follow the same staging system. […] Instead, leukemia is classified using other methods that focus on specific factors like white blood cell counts, genetic mutations, and overall disease progression. […] Recognizing the symptoms and understanding these classifications can help individuals and families navigate the diagnosis and treatment process effectively. […] The Rai system helps determine how far the leukemia has progressed, guiding treatment decisions and helping to predict the leukemia survival rate. […] This early stage of leukemia is marked by high white blood cell counts without significant symptoms. Patients may not need treatment right away, as the disease progresses slowly.

• #174 LLS | Stages of Leukemia

  https://lls.org/blog/stages-leukemia-understanding-classification-and-progression

  Staging is a method used to describe or classify cancer based on how much of it is present in the body. […] However, leukemia a type of blood cancer does not typically follow the same staging system. […] Instead, leukemia is classified using other methods that focus on specific factors like white blood cell counts, genetic mutations, and overall disease progression. […] Recognizing the symptoms and understanding these classifications can help individuals and families navigate the diagnosis and treatment process effectively. […] The Rai system helps determine how far the leukemia has progressed, guiding treatment decisions and helping to predict the leukemia survival rate. […] This early stage of leukemia is marked by high white blood cell counts without significant symptoms. Patients may not need treatment right away, as the disease progresses slowly.

• #175 Leukemia Stages and Survival Rate

  https://www.cancercenter.com/cancer-types/leukemia/stages

  Most cancers are staged based on the size and spread of tumors. However, because leukemia occurs in the developing blood cells in the bone marrow, leukemia staging is a little bit different. The stages of leukemia are often characterized by blood cell counts and the accumulation of leukemia cells in other organs, like the liver or spleen, with each subtype staged using a system designed specifically for leukemia. […] Making an educated treatment decision begins with the stage, or progression, of the disease. The stage of leukemia is one of the most important factors in evaluating treatment options. […] Due to the way this disease develops and spreads, chronic lymphocytic leukemia (CLL) staging is different from staging for the types of cancers that form tumors. Instead of rating the size and extent of tumors, the Rai staging system is based on blood cell counts.

• #176 LLS | Stages of Leukemia

  https://lls.org/blog/stages-leukemia-understanding-classification-and-progression

  Chronic myeloid leukemia (CML) progresses through three phases rather than stages. […] This beginning stage of leukemia often presents with few symptoms, and many patients may not feel sick. […] Hairy cell leukemia (HCL) typically causes a decrease in healthy blood cells, leading to symptoms like fatigue, frequent infections, and anemia. […] HCL is often classified based on the response to treatment, with doctors describing it as either active or in remission. […] Juvenile myelomonocytic leukemia (JMML) is a rare childhood leukemia that does not have traditional stages. […] Treatment for JMML often involves chemotherapy, and a stem cell transplant is the most common approach for achieving long-term remission. […] Large granular lymphocytic (LGL) leukemia is a rare, slow-progressing chronic leukemia characterized by the abnormal growth of large granular lymphocytes.

• #177 Leukemia Stages and Survival Rate

  https://www.cancercenter.com/cancer-types/leukemia/stages

  By identifying the stage of chronic lymphocytic leukemia, the care team may choose when to begin treatment and determine which CLL treatments to recommend. […] The Rai system of chronic lymphocytic leukemia staging is sometimes simplified into low risk (stage 0), medium risk (stage 1 and 2) and high risk (stage 3 and 4). The care team may use this classification to help determine when to begin treatment. […] In order to stage chronic myeloid leukemia (CML), the care team examines blood and bone marrow tests to determine the number of diseased cells. […] The majority of CML patients are diagnosed during this phase as a result of mild symptoms, particularly fatigue. […] If CML has not responded to treatment well during the chronic phase, it becomes more aggressive, which may lead to the accelerated phase. At this point, symptoms may become more noticeable. […] This is the most aggressive stage of chronic myeloid leukemia. Blastic refers to having more than 20 percent myeloblasts or lymphoblasts. Symptoms are similar to those of acute myeloid leukemia.

• #178 LLS | Stages of Leukemia

  https://lls.org/blog/stages-leukemia-understanding-classification-and-progression

  Chronic myeloid leukemia (CML) progresses through three phases rather than stages. […] This beginning stage of leukemia often presents with few symptoms, and many patients may not feel sick. […] Hairy cell leukemia (HCL) typically causes a decrease in healthy blood cells, leading to symptoms like fatigue, frequent infections, and anemia. […] HCL is often classified based on the response to treatment, with doctors describing it as either active or in remission. […] Juvenile myelomonocytic leukemia (JMML) is a rare childhood leukemia that does not have traditional stages. […] Treatment for JMML often involves chemotherapy, and a stem cell transplant is the most common approach for achieving long-term remission. […] Large granular lymphocytic (LGL) leukemia is a rare, slow-progressing chronic leukemia characterized by the abnormal growth of large granular lymphocytes.

• #179 Leukemia Stages and Survival Rate

  https://www.cancercenter.com/cancer-types/leukemia/stages

  By identifying the stage of chronic lymphocytic leukemia, the care team may choose when to begin treatment and determine which CLL treatments to recommend. […] The Rai system of chronic lymphocytic leukemia staging is sometimes simplified into low risk (stage 0), medium risk (stage 1 and 2) and high risk (stage 3 and 4). The care team may use this classification to help determine when to begin treatment. […] In order to stage chronic myeloid leukemia (CML), the care team examines blood and bone marrow tests to determine the number of diseased cells. […] The majority of CML patients are diagnosed during this phase as a result of mild symptoms, particularly fatigue. […] If CML has not responded to treatment well during the chronic phase, it becomes more aggressive, which may lead to the accelerated phase. At this point, symptoms may become more noticeable. […] This is the most aggressive stage of chronic myeloid leukemia. Blastic refers to having more than 20 percent myeloblasts or lymphoblasts. Symptoms are similar to those of acute myeloid leukemia.

• #180 Leukemia Stages and Survival Rate

  https://www.cancercenter.com/cancer-types/leukemia/stages

  By identifying the stage of chronic lymphocytic leukemia, the care team may choose when to begin treatment and determine which CLL treatments to recommend. […] The Rai system of chronic lymphocytic leukemia staging is sometimes simplified into low risk (stage 0), medium risk (stage 1 and 2) and high risk (stage 3 and 4). The care team may use this classification to help determine when to begin treatment. […] In order to stage chronic myeloid leukemia (CML), the care team examines blood and bone marrow tests to determine the number of diseased cells. […] The majority of CML patients are diagnosed during this phase as a result of mild symptoms, particularly fatigue. […] If CML has not responded to treatment well during the chronic phase, it becomes more aggressive, which may lead to the accelerated phase. At this point, symptoms may become more noticeable. […] This is the most aggressive stage of chronic myeloid leukemia. Blastic refers to having more than 20 percent myeloblasts or lymphoblasts. Symptoms are similar to those of acute myeloid leukemia.

• #181 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  There are four main types of leukemia and several subtypes. […] The goal is to kill as many leukemia cells as possible in your blood and bone marrow to achieve remission. In remission, blood cell counts return to normal levels, no leukemia cells are found in your blood, and all signs and symptoms of the disease disappear. […] Ultimately, your healthcare provider is the most reliable resource for understanding how your cancer affects your unique prognosis.

• #182 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  The outlook for people who have AML depends on several factors, including the patients age, general health, and whether they have previously been treated with chemotherapy for another medical condition. In general, younger, healthier patients who have no history of chemotherapy have better outcomes. The subtype of AML, whether the cancer cells have certain genetic changes, and a number of other factors also affect the prognosis.

• #183 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  There are four main types of leukemia and several subtypes. […] The goal is to kill as many leukemia cells as possible in your blood and bone marrow to achieve remission. In remission, blood cell counts return to normal levels, no leukemia cells are found in your blood, and all signs and symptoms of the disease disappear. […] Ultimately, your healthcare provider is the most reliable resource for understanding how your cancer affects your unique prognosis.

• #184 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  The outlook for people who have AML depends on several factors, including the patients age, general health, and whether they have previously been treated with chemotherapy for another medical condition. In general, younger, healthier patients who have no history of chemotherapy have better outcomes. The subtype of AML, whether the cancer cells have certain genetic changes, and a number of other factors also affect the prognosis.

• #185 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  The outlook for people who have AML depends on several factors, including the patients age, general health, and whether they have previously been treated with chemotherapy for another medical condition. In general, younger, healthier patients who have no history of chemotherapy have better outcomes. The subtype of AML, whether the cancer cells have certain genetic changes, and a number of other factors also affect the prognosis.

• #186 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  The outlook for people who have AML depends on several factors, including the patients age, general health, and whether they have previously been treated with chemotherapy for another medical condition. In general, younger, healthier patients who have no history of chemotherapy have better outcomes. The subtype of AML, whether the cancer cells have certain genetic changes, and a number of other factors also affect the prognosis.

• #187 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  The outlook for people who have AML depends on several factors, including the patients age, general health, and whether they have previously been treated with chemotherapy for another medical condition. In general, younger, healthier patients who have no history of chemotherapy have better outcomes. The subtype of AML, whether the cancer cells have certain genetic changes, and a number of other factors also affect the prognosis.

• #188 Acute Myeloid Leukemia (AML) > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/acute-myeloid-leukemia-aml

  The outlook for people who have AML depends on several factors, including the patients age, general health, and whether they have previously been treated with chemotherapy for another medical condition. In general, younger, healthier patients who have no history of chemotherapy have better outcomes. The subtype of AML, whether the cancer cells have certain genetic changes, and a number of other factors also affect the prognosis.

• #189 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #190 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #191 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #192 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #193 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #194 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #195 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #196 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #197 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #198 Disease progression of chronic lymphocytic leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/chronic-lymphocytic-leukemia-cll/disease-progression

  Cancer cells can spread from where they start to other parts of the body. […] Understanding how a type of cancer usually progresses helps your healthcare team plan your treatment and future care. […] Symptoms of the progression of CLL include: more than 10% weight loss in 6 months, extreme fatigue, fever for more than 2 weeks without any signs of infection, night sweats for longer than 1 month, an increasing number of CLL cells in the bone marrow that make the bone marrow not work properly, leading to anemia (lower numbers of healthy red blood cells) or thrombocytopenia (lower number of platelets in the blood), a spleen that is larger than normal and may be causing symptoms such as discomfort or a feeling of fullness, more areas of enlarged lymph nodes in the body that cause discomfort, an enlarged liver that causes discomfort, the number of lymphocytes increases by more than 50% in 2 months or doubles in less than 6 months (rapid doubling time). […] In rare cases, CLL develops into a high-grade non-Hodgkin lymphoma. This condition is called Richter transformation, and if this happens, it usually develops into a diffuse large B-cell lymphoma, which is treated like a lymphoma.

• #199 Leukemia symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/leukaemia-symptoms-signs/

  Leukemia symptoms commonly include fatigue, breathlessness, infections, and bruising or bleeding more easily. […] Most people with these symptoms wont have leukemia. But some people will, and the earlier its diagnosed, the higher the chance of treatment being successful. […] Even if you only have one symptom, if its unexplained, goes on for a long time, or is unusual for you, you should contact your GP. […] Leukemia symptoms commonly include: fatigue (tiredness that lasts a long time and doesnt improve with rest), bruising and bleeding more easily, or bleeding that takes longer to stop, infections that are more frequent, severe, or last longer, fever (high temperature), weight loss that is unexplained, swollen lymph nodes (glands in your neck, armpit and groin), breathlessness, feeling generally unwell.

• #200 Leukemia: Symptoms and early signs

  https://www.medicalnewstoday.com/articles/leukemia-symptoms

  Doctors may classify leukemia as either acute or chronic. Acute leukemia comes on suddenly, and the cancerous cells multiply rapidly. Chronic conditions result from slowly developing cancer cells, and it may take years before a person experiences any symptoms. […] However, acute and chronic leukemia have some similarities. They both cause flu-like symptoms, fatigue, and general feelings of being unwell. […] A person should see their doctor if they experience the following symptoms, which may be due to leukemia: loss of appetite, a low grade fever that does not go away, frequent and prolonged infections, unexplained fatigue, unexplained weight loss.

• #201 Blood cancer signs and symptoms – Leukaemia Foundation

  https://www.leukaemia.org.au/blood-cancer/blood-cancer-signs-and-symptoms/

  Blood cancer symptoms can be vague and easy to overlook, but it’s important to pay attention to changes in your body. Some of the most common signs include unexplained weight loss, fatigue, frequent infections, easy bruising or bleeding, night sweats, shortness of breath, and unusual lumps or swellings. If you notice any of these symptoms or something just doesn’t feel right, speak with your doctor. The earlier blood cancer is detected, the better the chances of successful treatment. […] Cause: very high level of white blood cells. Some types of blood cancer such as acute myeloid leukaemia (AML) develop very quickly. You may suddenly become very unwell. This is known as leukostasis. […] Not everyone will have the same symptoms, some people may have symptoms that are not listed here. Usually multiple symptoms are present and develop quickly. […] Leukostasis is a medical emergency and you must seek medical attention immediately. Call 000 – for a medical emergency.

• #202 Blood cancer symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/about-blood-cancer/blood-cancer-signs-symptoms/

  These symptoms can be caused by anaemia (a low level of red blood cells). […] These symptoms can be caused by a low level of platelets, which help the blood to clot. […] These symptoms can be caused by a low level of white blood cells, which fight infection. […] These can be caused by abnormal white blood cells building up in your lymph glands. […] Bone pain can be caused by damage to bones. […] Some people with lymphoma have drenching night sweats but we dont know yet what causes this. […] Some people with blood cancer experience itching but we dont know yet what causes this. […] Cancer cells and the bodys reaction to them can alter your bodys metabolism and reduce muscle and fat. […] The symptoms of acute blood cancer are caused by a very high level of white blood cells. […] Some types of blood cancer such as acute myeloid leukaemia (AML) develop very quickly and make you suddenly very unwell. This is known as leukostasis or blast crisis. Symptoms may include breathing problems and neurological symptoms like visual changes, confusion, vomiting, loss of muscle control or seizures. Anyone with these symptoms needs medical attention immediately.

• #203 Blood cancer signs and symptoms – Leukaemia Foundation

  https://www.leukaemia.org.au/blood-cancer/blood-cancer-signs-and-symptoms/

  Blood cancer symptoms can be vague and easy to overlook, but it’s important to pay attention to changes in your body. Some of the most common signs include unexplained weight loss, fatigue, frequent infections, easy bruising or bleeding, night sweats, shortness of breath, and unusual lumps or swellings. If you notice any of these symptoms or something just doesn’t feel right, speak with your doctor. The earlier blood cancer is detected, the better the chances of successful treatment. […] Cause: very high level of white blood cells. Some types of blood cancer such as acute myeloid leukaemia (AML) develop very quickly. You may suddenly become very unwell. This is known as leukostasis. […] Not everyone will have the same symptoms, some people may have symptoms that are not listed here. Usually multiple symptoms are present and develop quickly. […] Leukostasis is a medical emergency and you must seek medical attention immediately. Call 000 – for a medical emergency.

• #204 Blood cancer symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/about-blood-cancer/blood-cancer-signs-symptoms/

  These symptoms can be caused by anaemia (a low level of red blood cells). […] These symptoms can be caused by a low level of platelets, which help the blood to clot. […] These symptoms can be caused by a low level of white blood cells, which fight infection. […] These can be caused by abnormal white blood cells building up in your lymph glands. […] Bone pain can be caused by damage to bones. […] Some people with lymphoma have drenching night sweats but we dont know yet what causes this. […] Some people with blood cancer experience itching but we dont know yet what causes this. […] Cancer cells and the bodys reaction to them can alter your bodys metabolism and reduce muscle and fat. […] The symptoms of acute blood cancer are caused by a very high level of white blood cells. […] Some types of blood cancer such as acute myeloid leukaemia (AML) develop very quickly and make you suddenly very unwell. This is known as leukostasis or blast crisis. Symptoms may include breathing problems and neurological symptoms like visual changes, confusion, vomiting, loss of muscle control or seizures. Anyone with these symptoms needs medical attention immediately.

• #205 Blood cancer symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/about-blood-cancer/blood-cancer-signs-symptoms/

  These symptoms can be caused by anaemia (a low level of red blood cells). […] These symptoms can be caused by a low level of platelets, which help the blood to clot. […] These symptoms can be caused by a low level of white blood cells, which fight infection. […] These can be caused by abnormal white blood cells building up in your lymph glands. […] Bone pain can be caused by damage to bones. […] Some people with lymphoma have drenching night sweats but we dont know yet what causes this. […] Some people with blood cancer experience itching but we dont know yet what causes this. […] Cancer cells and the bodys reaction to them can alter your bodys metabolism and reduce muscle and fat. […] The symptoms of acute blood cancer are caused by a very high level of white blood cells. […] Some types of blood cancer such as acute myeloid leukaemia (AML) develop very quickly and make you suddenly very unwell. This is known as leukostasis or blast crisis. Symptoms may include breathing problems and neurological symptoms like visual changes, confusion, vomiting, loss of muscle control or seizures. Anyone with these symptoms needs medical attention immediately.

• #206 Blood cancer symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/about-blood-cancer/blood-cancer-signs-symptoms/

  These symptoms can be caused by anaemia (a low level of red blood cells). […] These symptoms can be caused by a low level of platelets, which help the blood to clot. […] These symptoms can be caused by a low level of white blood cells, which fight infection. […] These can be caused by abnormal white blood cells building up in your lymph glands. […] Bone pain can be caused by damage to bones. […] Some people with lymphoma have drenching night sweats but we dont know yet what causes this. […] Some people with blood cancer experience itching but we dont know yet what causes this. […] Cancer cells and the bodys reaction to them can alter your bodys metabolism and reduce muscle and fat. […] The symptoms of acute blood cancer are caused by a very high level of white blood cells. […] Some types of blood cancer such as acute myeloid leukaemia (AML) develop very quickly and make you suddenly very unwell. This is known as leukostasis or blast crisis. Symptoms may include breathing problems and neurological symptoms like visual changes, confusion, vomiting, loss of muscle control or seizures. Anyone with these symptoms needs medical attention immediately.

• #207 Signs and Symptoms of Acute Lymphocytic Leukemia (ALL) | American Cancer Society

  https://www.cancer.org/cancer/types/acute-lymphocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html

  If the thymus is enlarged, it may press on the SVC, causing the blood to back up in the veins. This is known as SVC syndrome. It can cause: Swelling in the face, neck, arms, and upper chest (sometimes with a bluish-red color), Headaches, Dizziness, Change in consciousness if it affects the brain. […] The SVC syndrome can be life-threatening, and needs to be treated right away.

• #208 Blood cancer signs and symptoms – Leukaemia Foundation

  https://www.leukaemia.org.au/blood-cancer/blood-cancer-signs-and-symptoms/

  Blood cancer symptoms can be vague and easy to overlook, but it’s important to pay attention to changes in your body. Some of the most common signs include unexplained weight loss, fatigue, frequent infections, easy bruising or bleeding, night sweats, shortness of breath, and unusual lumps or swellings. If you notice any of these symptoms or something just doesn’t feel right, speak with your doctor. The earlier blood cancer is detected, the better the chances of successful treatment. […] Cause: very high level of white blood cells. Some types of blood cancer such as acute myeloid leukaemia (AML) develop very quickly. You may suddenly become very unwell. This is known as leukostasis. […] Not everyone will have the same symptoms, some people may have symptoms that are not listed here. Usually multiple symptoms are present and develop quickly. […] Leukostasis is a medical emergency and you must seek medical attention immediately. Call 000 – for a medical emergency.

• #209 Leukemia symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/leukaemia-symptoms-signs/

  Leukemia symptoms commonly include fatigue, breathlessness, infections, and bruising or bleeding more easily. […] Most people with these symptoms wont have leukemia. But some people will, and the earlier its diagnosed, the higher the chance of treatment being successful. […] Even if you only have one symptom, if its unexplained, goes on for a long time, or is unusual for you, you should contact your GP. […] Leukemia symptoms commonly include: fatigue (tiredness that lasts a long time and doesnt improve with rest), bruising and bleeding more easily, or bleeding that takes longer to stop, infections that are more frequent, severe, or last longer, fever (high temperature), weight loss that is unexplained, swollen lymph nodes (glands in your neck, armpit and groin), breathlessness, feeling generally unwell.

• #210 Leukemia: Symptoms and early signs

  https://www.medicalnewstoday.com/articles/leukemia-symptoms

  Doctors may classify leukemia as either acute or chronic. Acute leukemia comes on suddenly, and the cancerous cells multiply rapidly. Chronic conditions result from slowly developing cancer cells, and it may take years before a person experiences any symptoms. […] However, acute and chronic leukemia have some similarities. They both cause flu-like symptoms, fatigue, and general feelings of being unwell. […] A person should see their doctor if they experience the following symptoms, which may be due to leukemia: loss of appetite, a low grade fever that does not go away, frequent and prolonged infections, unexplained fatigue, unexplained weight loss.

• #211 Leukemia: Symptoms and early signs

  https://www.medicalnewstoday.com/articles/leukemia-symptoms

  Doctors may classify leukemia as either acute or chronic. Acute leukemia comes on suddenly, and the cancerous cells multiply rapidly. Chronic conditions result from slowly developing cancer cells, and it may take years before a person experiences any symptoms. […] However, acute and chronic leukemia have some similarities. They both cause flu-like symptoms, fatigue, and general feelings of being unwell. […] A person should see their doctor if they experience the following symptoms, which may be due to leukemia: loss of appetite, a low grade fever that does not go away, frequent and prolonged infections, unexplained fatigue, unexplained weight loss.

• #212 Leukemia: Symptoms and early signs

  https://www.medicalnewstoday.com/articles/leukemia-symptoms

  Doctors may classify leukemia as either acute or chronic. Acute leukemia comes on suddenly, and the cancerous cells multiply rapidly. Chronic conditions result from slowly developing cancer cells, and it may take years before a person experiences any symptoms. […] However, acute and chronic leukemia have some similarities. They both cause flu-like symptoms, fatigue, and general feelings of being unwell. […] A person should see their doctor if they experience the following symptoms, which may be due to leukemia: loss of appetite, a low grade fever that does not go away, frequent and prolonged infections, unexplained fatigue, unexplained weight loss.

• #213 Leukemia: Symptoms and early signs

  https://www.medicalnewstoday.com/articles/leukemia-symptoms

  Doctors may classify leukemia as either acute or chronic. Acute leukemia comes on suddenly, and the cancerous cells multiply rapidly. Chronic conditions result from slowly developing cancer cells, and it may take years before a person experiences any symptoms. […] However, acute and chronic leukemia have some similarities. They both cause flu-like symptoms, fatigue, and general feelings of being unwell. […] A person should see their doctor if they experience the following symptoms, which may be due to leukemia: loss of appetite, a low grade fever that does not go away, frequent and prolonged infections, unexplained fatigue, unexplained weight loss.

• #214 Leukemia: Symptoms and early signs

  https://www.medicalnewstoday.com/articles/leukemia-symptoms

  Doctors may classify leukemia as either acute or chronic. Acute leukemia comes on suddenly, and the cancerous cells multiply rapidly. Chronic conditions result from slowly developing cancer cells, and it may take years before a person experiences any symptoms. […] However, acute and chronic leukemia have some similarities. They both cause flu-like symptoms, fatigue, and general feelings of being unwell. […] A person should see their doctor if they experience the following symptoms, which may be due to leukemia: loss of appetite, a low grade fever that does not go away, frequent and prolonged infections, unexplained fatigue, unexplained weight loss.

• #215 Leukemia symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/leukaemia-symptoms-signs/

  Leukemia symptoms commonly include fatigue, breathlessness, infections, and bruising or bleeding more easily. […] Most people with these symptoms wont have leukemia. But some people will, and the earlier its diagnosed, the higher the chance of treatment being successful. […] Even if you only have one symptom, if its unexplained, goes on for a long time, or is unusual for you, you should contact your GP. […] Leukemia symptoms commonly include: fatigue (tiredness that lasts a long time and doesnt improve with rest), bruising and bleeding more easily, or bleeding that takes longer to stop, infections that are more frequent, severe, or last longer, fever (high temperature), weight loss that is unexplained, swollen lymph nodes (glands in your neck, armpit and groin), breathlessness, feeling generally unwell.

• #216 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Swollen lymph nodes. These are enlarged lumps that can be seen or felt underneath the skin usually in the armpit, neck or groin area. Often, they can be the result of an everyday infection or allergy. However, they might be a sign of leukaemia, particularly if they are painless, last longer than two weeks, are hard or unmovable, or grow in size. […] Swollen and/or painful stomach. This can include a sharp pain or swelling in the stomach and constantly feeling full. […] Infections. Factors such as the duration and frequency of infections can help determine if they are a sign of leukaemia. Specific signs include a cough, fever or chest infection that is recurring or long lasting; and small cuts to your skin becoming infected more frequently. […] Night sweats. The temperature at which night sweats occur, and the quantity of sweat lost can help determine if a persons night sweats are a symptom of leukaemia. If night sweats are regular, drench you in sweat, or occur in cool environments its worth visiting your GP.

• #217 Leukemia symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/leukaemia-symptoms-signs/

  Leukemia symptoms commonly include fatigue, breathlessness, infections, and bruising or bleeding more easily. […] Most people with these symptoms wont have leukemia. But some people will, and the earlier its diagnosed, the higher the chance of treatment being successful. […] Even if you only have one symptom, if its unexplained, goes on for a long time, or is unusual for you, you should contact your GP. […] Leukemia symptoms commonly include: fatigue (tiredness that lasts a long time and doesnt improve with rest), bruising and bleeding more easily, or bleeding that takes longer to stop, infections that are more frequent, severe, or last longer, fever (high temperature), weight loss that is unexplained, swollen lymph nodes (glands in your neck, armpit and groin), breathlessness, feeling generally unwell.

• #218 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Pain in bones/joints. This can be a sharp pain or a constant dull ache in one or more bones. Bone pain caused by leukaemia is usually felt in the arms and legs, or in the ribs and sternum of the rib cage. Joint pain in ankles or wrists and swelling of large joints like the hips and shoulders can also be experienced. […] Shortness of breath. Symptoms of leukaemia can include breathlessness that comes on suddenly or during activities that would normally be effortless for the person, breathlessness lasting longer than a month, breathlessness that worsens over time and coughing lasting three weeks or more. […] Skin rashes. Skin rashes are likely to be unexplained and often have the appearance of small red and purple spots on the skin. […] Leukaemia symptoms in adults and children are very similar, however, symptoms in children can develop more quickly. The National Institute for Health and Care Excellence (NICE) recommends children be offered a very urgent blood count due to the acute nature of leukaemia in children. […] If you are experiencing any of these symptoms and you are concerned about blood cancer, please make sure to book an appointment with your GP. The faster leukaemia patients are diagnosed, the increased likelihood they will make a full recovery.

• #219 Leukemia symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/leukaemia-symptoms-signs/

  Leukemia symptoms commonly include fatigue, breathlessness, infections, and bruising or bleeding more easily. […] Most people with these symptoms wont have leukemia. But some people will, and the earlier its diagnosed, the higher the chance of treatment being successful. […] Even if you only have one symptom, if its unexplained, goes on for a long time, or is unusual for you, you should contact your GP. […] Leukemia symptoms commonly include: fatigue (tiredness that lasts a long time and doesnt improve with rest), bruising and bleeding more easily, or bleeding that takes longer to stop, infections that are more frequent, severe, or last longer, fever (high temperature), weight loss that is unexplained, swollen lymph nodes (glands in your neck, armpit and groin), breathlessness, feeling generally unwell.

• #220 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Pain in bones/joints. This can be a sharp pain or a constant dull ache in one or more bones. Bone pain caused by leukaemia is usually felt in the arms and legs, or in the ribs and sternum of the rib cage. Joint pain in ankles or wrists and swelling of large joints like the hips and shoulders can also be experienced. […] Shortness of breath. Symptoms of leukaemia can include breathlessness that comes on suddenly or during activities that would normally be effortless for the person, breathlessness lasting longer than a month, breathlessness that worsens over time and coughing lasting three weeks or more. […] Skin rashes. Skin rashes are likely to be unexplained and often have the appearance of small red and purple spots on the skin. […] Leukaemia symptoms in adults and children are very similar, however, symptoms in children can develop more quickly. The National Institute for Health and Care Excellence (NICE) recommends children be offered a very urgent blood count due to the acute nature of leukaemia in children. […] If you are experiencing any of these symptoms and you are concerned about blood cancer, please make sure to book an appointment with your GP. The faster leukaemia patients are diagnosed, the increased likelihood they will make a full recovery.

• #221 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Pain in bones/joints. This can be a sharp pain or a constant dull ache in one or more bones. Bone pain caused by leukaemia is usually felt in the arms and legs, or in the ribs and sternum of the rib cage. Joint pain in ankles or wrists and swelling of large joints like the hips and shoulders can also be experienced. […] Shortness of breath. Symptoms of leukaemia can include breathlessness that comes on suddenly or during activities that would normally be effortless for the person, breathlessness lasting longer than a month, breathlessness that worsens over time and coughing lasting three weeks or more. […] Skin rashes. Skin rashes are likely to be unexplained and often have the appearance of small red and purple spots on the skin. […] Leukaemia symptoms in adults and children are very similar, however, symptoms in children can develop more quickly. The National Institute for Health and Care Excellence (NICE) recommends children be offered a very urgent blood count due to the acute nature of leukaemia in children. […] If you are experiencing any of these symptoms and you are concerned about blood cancer, please make sure to book an appointment with your GP. The faster leukaemia patients are diagnosed, the increased likelihood they will make a full recovery.

• #222 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #223 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  The most common signs and symptoms of acute myelogenous leukemia in children are: […] Anemia occurs when normal red blood cells can’t be produced because the bone marrow is overcrowded by leukemia cells. The anemic child may be more tired, take more naps, look pale, and her heart may be racing. The number of red blood cells on a blood count (expressed as „hemoglobin” or „hematocrit”) will be below normal. […] When the bone marrow cannot produce enough platelets, bleeding can occur, especially when the platelet numbers are less than 10-20,000/mm3. Low platelets can cause a child to bruise or bleed more easily. […] Pain in bones and joints is usually a result of the bone marrow being crowded with leukemic blasts. This is often mistaken for „growing pains.” […] The child with leukemia often shows non-specific symptoms of infection such as fever and fatigue. Although the blood count of a child with leukemia may show a high number of white blood cells, these cells are immature and do not normally fight infection. As a result, the child may have difficulty recovering from an ordinary childhood infection or may develop unusual infections.

• #224 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #225 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #226 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #227 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #228 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #229 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #230 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #231 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #232 Leukemia (for Parents) | Nemours KidsHealth

  https://kidshealth.org/en/parents/cancer-leukemia.html

  Kids with leukemia may get more viral or bacterial infections than other kids. These happen because their white blood cells can’t fight infections. […] They also may get anemia, which is when there’s a low number of red blood cells. This happens because leukemia cells crowd the bone marrow. This prevents bone marrow from making the usual amount of oxygen-carrying red blood cells. […] Other symptoms of leukemia can include: pain in the bones or joints, sometimes causing a limp; swollen lymph nodes (swollen glands) in the neck, groin, or elsewhere; poor appetite and weight loss; fevers with no other symptoms; belly pain. […] Sometimes leukemia can spread, or metastasize. If it spreads to the brain, symptoms may include headaches, seizures, balance problems, or vision problems. If it spreads to the lymph nodes in the chest, symptoms may include breathing problems and chest pain.

• #233 Acute Myelogenous Leukemia (AML) | Children’s Hospital of Philadelphia

  https://www.chop.edu/conditions-diseases/acute-myelogenous-leukemia-aml

  Leukemia cells can collect in the kidneys, liver, and spleen, causing enlargement of these organs which can cause pain in the abdomen. This pain may lead to loss of appetite and weight loss. […] Lymph nodes filter the blood. Leukemia cells often collect in the nodes, causing swelling. Swelling occurs in lymph nodes in the neck, under the arms, in the groin, and chest. Sometimes it is difficult to distinguish the lymph nodes of leukemia from those that are a normal part of the body’s response to infection or allergy. […] In leukemia, cells can clump together in the thymus a gland under the breastbone and around the throat. This mass of cells can cause difficulty breathing. Any wheezing, coughing, and/or labored or painful breathing requires immediate medical attention.

• #234 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  Leukemia is a form of cancer that affects white blood cells. […] In teens, symptoms of leukemia include bone pain, enlarged lymph nodes, fever, fatigue, frequent infections, and bruising or bleeding easily. […] The symptoms of this type of cancer usually include a fever that wont go away, recurring infections, fatigue, and pale skin. […] Common leukemia signs and symptoms include: Fever or chills, Persistent fatigue, weakness, Frequent or severe infections, Losing weight without trying, Swollen lymph nodes, enlarged liver or spleen, Easy bleeding or bruising, Recurrent nosebleeds, Tiny red spots in your skin (petechiae), Excessive sweating, especially at night, Bone pain or tenderness. […] The symptoms of teenage leukemia vary depending on the type of leukemia, age at the time of diagnosis, and which organ systems are most significantly impacted.

• #235 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  An elevated body temperature is the result of the rapid growth of leukemia cells in the body. […] While commonly attributed to a urinary tract infection, blood in the urine is a symptom of leukemia at all development stages. […] The swollen lymph nodes are a result of the sometimes-rapid growth of cancer cells in the body. […] An abnormal increase in the number of white blood cells in the blood results from the cancerous proliferation of white blood cells. […] Organ infections are common with childhood leukemia due to a shortage of normal white blood cells. […] One of the side effects or signs of leukemia is feeling tired all the time, and weak. […] Fatigue is a key factor with leukemia diagnosis due to inflammation in the body.

• #236 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  Leukemia is a form of cancer that affects white blood cells. […] In teens, symptoms of leukemia include bone pain, enlarged lymph nodes, fever, fatigue, frequent infections, and bruising or bleeding easily. […] The symptoms of this type of cancer usually include a fever that wont go away, recurring infections, fatigue, and pale skin. […] Common leukemia signs and symptoms include: Fever or chills, Persistent fatigue, weakness, Frequent or severe infections, Losing weight without trying, Swollen lymph nodes, enlarged liver or spleen, Easy bleeding or bruising, Recurrent nosebleeds, Tiny red spots in your skin (petechiae), Excessive sweating, especially at night, Bone pain or tenderness. […] The symptoms of teenage leukemia vary depending on the type of leukemia, age at the time of diagnosis, and which organ systems are most significantly impacted.

• #237 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  Leukemia is a form of cancer that affects white blood cells. […] In teens, symptoms of leukemia include bone pain, enlarged lymph nodes, fever, fatigue, frequent infections, and bruising or bleeding easily. […] The symptoms of this type of cancer usually include a fever that wont go away, recurring infections, fatigue, and pale skin. […] Common leukemia signs and symptoms include: Fever or chills, Persistent fatigue, weakness, Frequent or severe infections, Losing weight without trying, Swollen lymph nodes, enlarged liver or spleen, Easy bleeding or bruising, Recurrent nosebleeds, Tiny red spots in your skin (petechiae), Excessive sweating, especially at night, Bone pain or tenderness. […] The symptoms of teenage leukemia vary depending on the type of leukemia, age at the time of diagnosis, and which organ systems are most significantly impacted.

• #238 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  Leukemia is a form of cancer that affects white blood cells. […] In teens, symptoms of leukemia include bone pain, enlarged lymph nodes, fever, fatigue, frequent infections, and bruising or bleeding easily. […] The symptoms of this type of cancer usually include a fever that wont go away, recurring infections, fatigue, and pale skin. […] Common leukemia signs and symptoms include: Fever or chills, Persistent fatigue, weakness, Frequent or severe infections, Losing weight without trying, Swollen lymph nodes, enlarged liver or spleen, Easy bleeding or bruising, Recurrent nosebleeds, Tiny red spots in your skin (petechiae), Excessive sweating, especially at night, Bone pain or tenderness. […] The symptoms of teenage leukemia vary depending on the type of leukemia, age at the time of diagnosis, and which organ systems are most significantly impacted.

• #239 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  Leukemia is a form of cancer that affects white blood cells. […] In teens, symptoms of leukemia include bone pain, enlarged lymph nodes, fever, fatigue, frequent infections, and bruising or bleeding easily. […] The symptoms of this type of cancer usually include a fever that wont go away, recurring infections, fatigue, and pale skin. […] Common leukemia signs and symptoms include: Fever or chills, Persistent fatigue, weakness, Frequent or severe infections, Losing weight without trying, Swollen lymph nodes, enlarged liver or spleen, Easy bleeding or bruising, Recurrent nosebleeds, Tiny red spots in your skin (petechiae), Excessive sweating, especially at night, Bone pain or tenderness. […] The symptoms of teenage leukemia vary depending on the type of leukemia, age at the time of diagnosis, and which organ systems are most significantly impacted.

• #240 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  Leukemia is a form of cancer that affects white blood cells. […] In teens, symptoms of leukemia include bone pain, enlarged lymph nodes, fever, fatigue, frequent infections, and bruising or bleeding easily. […] The symptoms of this type of cancer usually include a fever that wont go away, recurring infections, fatigue, and pale skin. […] Common leukemia signs and symptoms include: Fever or chills, Persistent fatigue, weakness, Frequent or severe infections, Losing weight without trying, Swollen lymph nodes, enlarged liver or spleen, Easy bleeding or bruising, Recurrent nosebleeds, Tiny red spots in your skin (petechiae), Excessive sweating, especially at night, Bone pain or tenderness. […] The symptoms of teenage leukemia vary depending on the type of leukemia, age at the time of diagnosis, and which organ systems are most significantly impacted.

• #241 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  Leukemia is a form of cancer that affects white blood cells. […] In teens, symptoms of leukemia include bone pain, enlarged lymph nodes, fever, fatigue, frequent infections, and bruising or bleeding easily. […] The symptoms of this type of cancer usually include a fever that wont go away, recurring infections, fatigue, and pale skin. […] Common leukemia signs and symptoms include: Fever or chills, Persistent fatigue, weakness, Frequent or severe infections, Losing weight without trying, Swollen lymph nodes, enlarged liver or spleen, Easy bleeding or bruising, Recurrent nosebleeds, Tiny red spots in your skin (petechiae), Excessive sweating, especially at night, Bone pain or tenderness. […] The symptoms of teenage leukemia vary depending on the type of leukemia, age at the time of diagnosis, and which organ systems are most significantly impacted.

• #242 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  An elevated body temperature is the result of the rapid growth of leukemia cells in the body. […] While commonly attributed to a urinary tract infection, blood in the urine is a symptom of leukemia at all development stages. […] The swollen lymph nodes are a result of the sometimes-rapid growth of cancer cells in the body. […] An abnormal increase in the number of white blood cells in the blood results from the cancerous proliferation of white blood cells. […] Organ infections are common with childhood leukemia due to a shortage of normal white blood cells. […] One of the side effects or signs of leukemia is feeling tired all the time, and weak. […] Fatigue is a key factor with leukemia diagnosis due to inflammation in the body.

• #243 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  An elevated body temperature is the result of the rapid growth of leukemia cells in the body. […] While commonly attributed to a urinary tract infection, blood in the urine is a symptom of leukemia at all development stages. […] The swollen lymph nodes are a result of the sometimes-rapid growth of cancer cells in the body. […] An abnormal increase in the number of white blood cells in the blood results from the cancerous proliferation of white blood cells. […] Organ infections are common with childhood leukemia due to a shortage of normal white blood cells. […] One of the side effects or signs of leukemia is feeling tired all the time, and weak. […] Fatigue is a key factor with leukemia diagnosis due to inflammation in the body.

• #244 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  An elevated body temperature is the result of the rapid growth of leukemia cells in the body. […] While commonly attributed to a urinary tract infection, blood in the urine is a symptom of leukemia at all development stages. […] The swollen lymph nodes are a result of the sometimes-rapid growth of cancer cells in the body. […] An abnormal increase in the number of white blood cells in the blood results from the cancerous proliferation of white blood cells. […] Organ infections are common with childhood leukemia due to a shortage of normal white blood cells. […] One of the side effects or signs of leukemia is feeling tired all the time, and weak. […] Fatigue is a key factor with leukemia diagnosis due to inflammation in the body.

• #245 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  An elevated body temperature is the result of the rapid growth of leukemia cells in the body. […] While commonly attributed to a urinary tract infection, blood in the urine is a symptom of leukemia at all development stages. […] The swollen lymph nodes are a result of the sometimes-rapid growth of cancer cells in the body. […] An abnormal increase in the number of white blood cells in the blood results from the cancerous proliferation of white blood cells. […] Organ infections are common with childhood leukemia due to a shortage of normal white blood cells. […] One of the side effects or signs of leukemia is feeling tired all the time, and weak. […] Fatigue is a key factor with leukemia diagnosis due to inflammation in the body.

• #246 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  An elevated body temperature is the result of the rapid growth of leukemia cells in the body. […] While commonly attributed to a urinary tract infection, blood in the urine is a symptom of leukemia at all development stages. […] The swollen lymph nodes are a result of the sometimes-rapid growth of cancer cells in the body. […] An abnormal increase in the number of white blood cells in the blood results from the cancerous proliferation of white blood cells. […] Organ infections are common with childhood leukemia due to a shortage of normal white blood cells. […] One of the side effects or signs of leukemia is feeling tired all the time, and weak. […] Fatigue is a key factor with leukemia diagnosis due to inflammation in the body.

• #247 Teenage Leukemia Symptoms | Early Signs Of Teen Cancer

  https://fwaya.org/teenage-leukemia-symptoms/

  An elevated body temperature is the result of the rapid growth of leukemia cells in the body. […] While commonly attributed to a urinary tract infection, blood in the urine is a symptom of leukemia at all development stages. […] The swollen lymph nodes are a result of the sometimes-rapid growth of cancer cells in the body. […] An abnormal increase in the number of white blood cells in the blood results from the cancerous proliferation of white blood cells. […] Organ infections are common with childhood leukemia due to a shortage of normal white blood cells. […] One of the side effects or signs of leukemia is feeling tired all the time, and weak. […] Fatigue is a key factor with leukemia diagnosis due to inflammation in the body.

• #248 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #249 Symptoms of leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/leukemia/signs-and-symptoms

  The signs or symptoms of leukemia may vary depending on whether you have an acute or chronic type of leukemia. […] Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. […] Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test. […] Other health conditions can cause the same symptoms as leukemia. […] Fatigue, a general feeling of discomfort or illness (called malaise), loss of appetite, weight loss, fever, shortness of breath, paleness, rapid heartbeat (called palpitations), weakness, dizziness, easy bruising, frequent or severe nose bleeds, bleeding gums, bleeding in the middle of a menstrual cycle or heavy menstrual flow, tiny, flat, red spots caused by bleeding just under the surface of the skin (called petechiae), frequent infections in the lungs, urinary tract or gums or around the anus, frequent cold sores, vomiting, headache, sore throat, night sweats, bone or joint pain, enlarged lymph nodes in the neck, underarm, groin or above the collarbone, abdominal discomfort or feeling of fullness, vision problems, sores in the eyes, swelling of the testicles, chloroma a collection of leukemia cells, or blasts, under the skin or in other parts of the body, leukemia cutis appears as sores or as patches of any size that are usually pink or tan in colour, leukocytoclastic vasculitis a condition that looks like an allergic reaction on the skin and usually causes sores on the hands and feet, Sweets syndrome, or acute febrile neutrophilic dermatosis causes fever and painful sores that may appear anywhere on the body.

• #250 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Pain in bones/joints. This can be a sharp pain or a constant dull ache in one or more bones. Bone pain caused by leukaemia is usually felt in the arms and legs, or in the ribs and sternum of the rib cage. Joint pain in ankles or wrists and swelling of large joints like the hips and shoulders can also be experienced. […] Shortness of breath. Symptoms of leukaemia can include breathlessness that comes on suddenly or during activities that would normally be effortless for the person, breathlessness lasting longer than a month, breathlessness that worsens over time and coughing lasting three weeks or more. […] Skin rashes. Skin rashes are likely to be unexplained and often have the appearance of small red and purple spots on the skin. […] Leukaemia symptoms in adults and children are very similar, however, symptoms in children can develop more quickly. The National Institute for Health and Care Excellence (NICE) recommends children be offered a very urgent blood count due to the acute nature of leukaemia in children. […] If you are experiencing any of these symptoms and you are concerned about blood cancer, please make sure to book an appointment with your GP. The faster leukaemia patients are diagnosed, the increased likelihood they will make a full recovery.

• #251 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Leukemia symptoms vary, depending on the type of leukemia. Common leukemia signs and symptoms include: Fever or chills […] Persistent fatigue, weakness […] Frequent or severe infections […] Losing weight without trying […] Swollen lymph nodes, enlarged liver or spleen […] Easy bleeding or bruising […] Recurrent nosebleeds […] Tiny red spots in your skin (petechiae) […] Excessive sweating, especially at night […] Bone pain or tenderness. […] Leukemia symptoms are often vague and not specific. You may overlook early leukemia symptoms because they may resemble symptoms of the flu and other common illnesses. […] When this happens, blood cell production becomes out of control. Over time, these abnormal cells can crowd out healthy blood cells in the bone marrow, leading to fewer healthy white blood cells, red blood cells and platelets, causing the signs and symptoms of leukemia.

• #252 Leukemia: Symptoms, Signs, Causes, Types & Treatment

  https://my.clevelandclinic.org/health/diseases/4365-leukemia

  Leukemia starts when the DNA of a single cell in your bone marrow changes (mutates) and cant develop and function normally. […] Symptoms depend, in part, on the type of leukemia. For instance, if you have a chronic form of leukemia, you may not have noticeable symptoms in the early stages. Common signs and symptoms of leukemia include: Fatigue, tiring easily. Fever or night sweats. Frequent infections. Shortness of breath. Pale skin. Unexplained weight loss. Bone/joint pain or tenderness. Pain or full feeling under your ribs on the left side. Swollen lymph nodes in your neck, underarm, groin or stomach, an enlarged spleen or liver. Bruising and bleeding easily, including nosebleeds, bleeding gums, a rash that looks like tiny red spots in skin (petechiae) or purplish/darkened skin patches.

• #253 Leukemia – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/leukemia/symptoms-causes/syc-20374373

  Acute leukemia requires aggressive, timely treatment. Chronic leukemia involves more-mature blood cells. These blood cells replicate or accumulate more slowly and can function normally for a period of time. Some forms of chronic leukemia initially produce no early symptoms and can go unnoticed or undiagnosed for years. […] A person with CML may have few or no symptoms for months or years before entering a phase in which the leukemia cells grow more quickly.

• #254 Symptoms of leukemia | Canadian Cancer Society

  https://cancer.ca/en/cancer-information/cancer-types/leukemia/signs-and-symptoms

  The signs or symptoms of leukemia may vary depending on whether you have an acute or chronic type of leukemia. […] Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. […] Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test. […] Other health conditions can cause the same symptoms as leukemia. […] Fatigue, a general feeling of discomfort or illness (called malaise), loss of appetite, weight loss, fever, shortness of breath, paleness, rapid heartbeat (called palpitations), weakness, dizziness, easy bruising, frequent or severe nose bleeds, bleeding gums, bleeding in the middle of a menstrual cycle or heavy menstrual flow, tiny, flat, red spots caused by bleeding just under the surface of the skin (called petechiae), frequent infections in the lungs, urinary tract or gums or around the anus, frequent cold sores, vomiting, headache, sore throat, night sweats, bone or joint pain, enlarged lymph nodes in the neck, underarm, groin or above the collarbone, abdominal discomfort or feeling of fullness, vision problems, sores in the eyes, swelling of the testicles, chloroma a collection of leukemia cells, or blasts, under the skin or in other parts of the body, leukemia cutis appears as sores or as patches of any size that are usually pink or tan in colour, leukocytoclastic vasculitis a condition that looks like an allergic reaction on the skin and usually causes sores on the hands and feet, Sweets syndrome, or acute febrile neutrophilic dermatosis causes fever and painful sores that may appear anywhere on the body.

• #255 Leukemia symptoms and signs | Blood Cancer UK

  https://bloodcancer.org.uk/understanding-blood-cancer/leukaemia/leukaemia-symptoms-signs/

  Leukemia symptoms commonly include fatigue, breathlessness, infections, and bruising or bleeding more easily. […] Most people with these symptoms wont have leukemia. But some people will, and the earlier its diagnosed, the higher the chance of treatment being successful. […] Even if you only have one symptom, if its unexplained, goes on for a long time, or is unusual for you, you should contact your GP. […] Leukemia symptoms commonly include: fatigue (tiredness that lasts a long time and doesnt improve with rest), bruising and bleeding more easily, or bleeding that takes longer to stop, infections that are more frequent, severe, or last longer, fever (high temperature), weight loss that is unexplained, swollen lymph nodes (glands in your neck, armpit and groin), breathlessness, feeling generally unwell.

• #256 Signs of Leukaemia & Leukaemia Symptoms | Leukaemia UK

  https://www.leukaemiauk.org.uk/about-leukaemia/signs-symptoms/

  Pain in bones/joints. This can be a sharp pain or a constant dull ache in one or more bones. Bone pain caused by leukaemia is usually felt in the arms and legs, or in the ribs and sternum of the rib cage. Joint pain in ankles or wrists and swelling of large joints like the hips and shoulders can also be experienced. […] Shortness of breath. Symptoms of leukaemia can include breathlessness that comes on suddenly or during activities that would normally be effortless for the person, breathlessness lasting longer than a month, breathlessness that worsens over time and coughing lasting three weeks or more. […] Skin rashes. Skin rashes are likely to be unexplained and often have the appearance of small red and purple spots on the skin. […] Leukaemia symptoms in adults and children are very similar, however, symptoms in children can develop more quickly. The National Institute for Health and Care Excellence (NICE) recommends children be offered a very urgent blood count due to the acute nature of leukaemia in children. […] If you are experiencing any of these symptoms and you are concerned about blood cancer, please make sure to book an appointment with your GP. The faster leukaemia patients are diagnosed, the increased likelihood they will make a full recovery.

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