Zespół wymiotów cyklicznych
Objawy
Zespół wymiotów cyklicznych (CVS) to rzadkie schorzenie charakteryzujące się nawracającymi, stereotypowymi epizodami intensywnych nudności i wymiotów, które mogą występować nawet do 20 razy na godzinę, trwając od kilku godzin do kilku dni (średnio około 24 godziny, mediana 43 godziny). Przebieg choroby obejmuje cztery fazy: prodromalną (z objawami takimi jak nadmierne pocenie, nudności, bladość skóry), fazę wymiotną, fazę zdrowienia oraz fazę międzynapadową, w której pacjent jest wolny od objawów. Epizody często rozpoczynają się w nocy lub wczesnym rankiem i mogą być wyzwalane przez infekcje (41%), stres (66%), głodówkę, brak snu, czy miesiączkę. Towarzyszą im objawy autonomiczne (tachykardia, nadmierne ślinienie, zawroty głowy) oraz neurologiczne (ból głowy u 42%, fotofobia u 38%, fonofobia u 30%). U około 80% pacjentów występuje ból brzucha, który może imitować ostry brzuch i prowadzić do niepotrzebnych interwencji chirurgicznych. CVS jest często powiązany z migreną, a około 75% dzieci z CVS rozwija migreny w dorosłości. Powikłania obejmują odwodnienie, uszkodzenia przełyku (pęknięcia Mallory’ego-Weissa), oraz korozję szkliwa zębów.
- Charakterystyka Zespołu Wymiotów Cyklicznych
- Fazy Zespołu Wymiotów Cyklicznych
- Główne objawy podczas epizodu wymiotów
- Nudności i wymioty
- Ból brzucha
- Objawy autonomiczne
- Objawy neurologiczne
- Objawy żołądkowo-jelitowe
- Inne objawy
- Czynniki wyzwalające epizody
- Charakterystyczne cechy epizodów
- Powikłania i wpływ CVS
- Odwodnienie
- Uszkodzenie przewodu pokarmowego
- Próchnica zębów
- Wpływ na jakość życia
- Schorzenia współistniejące
- Przebieg choroby i rokowanie
- Szczególne cechy CVS u dzieci i dorosłych
- Zespół wymiotów cyklicznych Plus
- Związek z migreną
- Podsumowanie
Charakterystyka Zespołu Wymiotów Cyklicznych
Zespół wymiotów cyklicznych (ang. Cyclic Vomiting Syndrome, CVS) to rzadkie schorzenie charakteryzujące się nawracającymi epizodami intensywnych nudności i wymiotów, które występują nagle, bez wyraźnej przyczyny. Epizody te mogą trwać od kilku godzin do kilku dni i przeplatają się z okresami całkowitego zdrowia, kiedy pacjent nie doświadcza żadnych objawów12. Istotną cechą CVS jest stereotypowy charakter ataków – zazwyczaj zaczynają się o tej samej porze dnia, trwają podobny czas i przebiegają z tymi samymi objawami o podobnym nasileniu3.
Schorzenie to występuje we wszystkich grupach wiekowych, chociaż najczęściej diagnozowane jest u dzieci, zwykle w wieku 3-7 lat. Coraz częściej jednak rozpoznaje się je również u osób dorosłych45. Wielu pacjentów z CVS doświadcza późniejszego przekształcenia się schorzenia w migreny, gdy dorosną6.
Fazy Zespołu Wymiotów Cyklicznych
CVS charakteryzuje się czterema wyraźnymi fazami, które tworzą cykliczny wzorzec78:
Faza prodromalna
Faza ta poprzedza właściwy atak wymiotów, kiedy pacjent czuje nadchodzący epizod. Charakteryzuje się intensywnym poceniem się i nudnościami, z bólem brzucha lub bez niego9. Skóra pacjenta może wyglądać niezwykle blado10. Faza ta może trwać od kilku minut do kilku godzin11. Około 61-93% dorosłych pacjentów zgłasza występowanie prodromów przed właściwym atakiem12.
U niektórych pacjentów mogą wystąpić także inne objawy prodromalne, takie jak: nadmierne wydzielanie śliny, nietolerancja zimna i ciepła, letarg, a także niepokój i uczucie paniki13. Wielu pacjentów opisuje nagły początek tej fazy jako uczucie „przełączenia się”, co sugeruje zmianę stanu układu nerwowego14.
Faza wymiotna
Główne objawy tej fazy to silne nudności, wymioty i odruchy wymiotne15. W szczytowym momencie tej fazy pacjent może wymiotować nawet kilka razy na godzinę16, często co 5-10 minut przez kilka godzin17. Wymioty mogą być tak nasilone, że u pacjenta może dojść do niebezpiecznej utraty płynów (odwodnienie)18.
Epizody wymiotów często zaczynają się w nocy lub wczesnym rankiem1920. Faza wymiotna może trwać od kilku godzin do kilku dni21, przy czym średni czas trwania epizodu wynosi około 24 godziny (mediana 43 godziny)22.
Podczas tej fazy pacjenci często opisują nudności jako najbardziej dokuczliwy objaw – są nieustępujące, całkowicie nieustępujące po wymiotach i znikają dopiero, gdy dziecko zaśnie lub epizod się skończy23. Niektórzy pacjenci podczas tej fazy są opisywani jako będący w „świadomej śpiączce” i wykazują letarg, wycofanie, a czasem dezorientację24.
Faza zdrowienia
Faza zdrowienia rozpoczyna się, gdy ustają wymioty i odruchy wymiotne, a nudności stają się mniej nasilone lub ustępują całkowicie25. W tej fazie pacjent zaczyna powracać do normalnego stanu, ponownie pojawia się apetyt i energia26. Faza zdrowienia może trwać od kilku minut do nawet dziesięciu dni27.
U niektórych pacjentów powrót do zdrowia następuje stopniowo, u innych szybko28. Niektórzy pacjenci mogą wrócić do jedzenia w ciągu kilku godzin, ale wielu potrzebuje kilku dni, aby powrócić do regularnej diety i odzyskać energię29.
Faza międzynapadowa
Faza ta występuje między epizodami wymiotów, gdy pacjent jest względnie wolny od objawów30. Zazwyczaj trwa od kilku tygodni do kilku miesięcy31. W tym okresie pacjent zazwyczaj czuje się dobrze i nie doświadcza nudności ani wymiotów32.
Chociaż większość pacjentów wraca do normalnego stanu zdrowia między epizodami, około 30% może doświadczać łagodnych nudności i dyspepsji między epizodami33. U niektórych dorosłych pacjentów z czasem może dojść do utraty cyklicznego charakteru objawów, a 63% z nich rozwija objawy między epizodami (często nudności) – ten wzorzec nazywany jest koalescencją34.
Główne objawy podczas epizodu wymiotów
Podczas epizodu wymiotów cyklicznych pacjenci doświadczają szeregu objawów, które mogą być niezwykle uciążliwe i wyniszczające35:
Nudności i wymioty
Głównym objawem CVS są intensywne nudności i wymioty, które mogą występować nawet kilka razy na godzinę36. Wymioty mogą być tak nasilone, że pacjent może wymiotować do 20 razy na godzinę37. U wielu pacjentów nudności są najbardziej dokuczliwym objawem – są uporczywe i nie ustępują nawet po wymiotach3839.
Oprócz wymiotów, pacjenci często doświadczają odruchów wymiotnych (odruchy wymiotne bez treści – „suche wymioty”)40. Intensywne wymioty mogą prowadzić do poważnego odwodnienia, które może zagrażać życiu, szczególnie u małych dzieci41.
Ból brzucha
Ból brzucha występuje u około 80% pacjentów z CVS42 i może być na tyle silny, że początkowo może przypominać ostry brzuch i prowadzić do laparotomii43. Ból brzucha często poprzedza wymioty i może być jednym z pierwszych objawów nadchodzącego epizodu44.
Objawy autonomiczne
Podczas epizodu CVS często występują objawy autonomiczne, takie jak4546:
- Nadmierne pocenie się
- Bladość skóry
- Tachykardia
- Zawroty głowy
- Nadmierne ślinienie się
- Uczucie zimna i gorąca
Objawy neurologiczne
Wielu pacjentów z CVS doświadcza objawów neurologicznych, co potwierdza związek między migrenami a CVS49:
- Bóle głowy (występują u około 42% pacjentów)
- Nadwrażliwość na światło (fotofobia) – u około 38% pacjentów
- Nadwrażliwość na dźwięki (fonofobia) – u około 30% pacjentów
- Zawroty głowy (u około 26% pacjentów)
U niektórych pacjentów z CVS mogą występować również parestezje kończyn, hiperestezja i uczucie depersonalizacji51.
Objawy żołądkowo-jelitowe
Oprócz wymiotów i bólu brzucha, pacjenci z CVS mogą doświadczać innych objawów ze strony przewodu pokarmowego52:
- Biegunka (występuje u około jednej trzeciej pacjentów z CVS)
- Uczucie wzdęcia brzucha
- Pieczenie w nadbrzuszu
- Niezdolność do odbijania lub nadmierne odbijanie
- Trudności z oddawaniem stolca lub gazów
Inne objawy
Podczas epizodu CVS mogą występować również inne objawy54:
- Gorączka (występuje u około jednej trzeciej pacjentów)
- Skrajne zmęczenie i osłabienie
- Brak apetytu
- Wzmożone pragnienie
- Nadmierne ślinienie się
- Dreszcze lub drżenie
- Uczucie lęku lub paniki
Czynniki wyzwalające epizody
Epizody nudności, wymiotów i letargu mogą występować regularnie lub pozornie losowo, albo mogą być wyzwalane przez różne czynniki57. Około 68% rodzin jest w stanie zidentyfikować zdarzenia, które wydają się wywoływać epizod u pacjenta58. Najczęstszymi czynnikami wyzwalającymi są5960:
- Infekcje – najczęstszym zdarzeniem wyzwalającym są infekcje (41%), szczególnie przewlekłe zapalenie zatok
- Stres emocjonalny i psychologiczny – lęk obecny u pacjentów z CVS, w tym zaburzenia paniki, może wywoływać ataki w 66% przypadków
- Podekscytowanie – zwłaszcza u dzieci
- Okresy bez jedzenia (głodówka)
- Skrajne temperatury
- Brak snu
- Nadmierny wysiłek
- Alergie
- Spożywanie niektórych pokarmów lub alkoholu – np. czekolada czy ser
- Miesiączka – u niektórych kobiet syndrom może występować w tym samym czasie co cykl miesiączkowy
- Choroba lokomocyjna
Charakterystyczne cechy epizodów
Epizody wymiotów w zespole wymiotów cyklicznych mają kilka wyróżniających cech64:
Stereotypowy charakter
Jedną z najbardziej charakterystycznych cech CVS jest stereotypowy charakter epizodów – każdy nowy epizod przypomina poprzednie65. Objawy, pora dnia, częstotliwość, nasilenie i długość każdego epizodu są zwykle takie same dla danej osoby66. Ta cecha jest pomocna przy diagnozowaniu CVS67.
Czas trwania
Epizody wymiotów mogą trwać od kilku godzin do kilku dni68. Najczęściej trwają od 1 do 3 dni69, ale mogą trwać nawet do 10 dni70. U dzieci epizody zwykle trwają od 24 do 48 godzin, podczas gdy dorośli mogą mieć objawy przez prawie tydzień71.
Częstotliwość
Częstotliwość epizodów CVS jest zróżnicowana. Mogą one występować co kilka dni, co kilka tygodni lub co kilka miesięcy72. Około połowa dzieci ma ataki co dwa do czterech tygodni, natomiast dorośli mogą mieć epizody rzadziej73. Częstotliwość epizodów CVS waha się od jednego epizodu co dwa-trzy tygodnie do trzech razy w roku74.
Jeśli choroba nie jest leczona, epizody zwykle występują od 4 do 12 razy w roku75. U niektórych pacjentów z czasem może dojść do pogorszenia przebiegu CVS, przejawiającego się zbliżaniem się do siebie epizodów w czasie (koalescencja)7677.
Pora rozpoczęcia
Epizody wymiotów często zaczynają się w nocy lub wczesnym rankiem7879. Dla niektórych pacjentów ataki występują w typowych, jednolitych porach, najczęściej rano80. Dla innych pacjentów nie ma rozpoznawalnego wzorca czasowego81.
Powikłania i wpływ CVS
Zespół wymiotów cyklicznych może prowadzić do różnych powikłań i mieć znaczący wpływ na życie pacjenta82:
Odwodnienie
Nadmierne wymioty powodują szybką utratę wody przez organizm. Ciężkie przypadki odwodnienia mogą wymagać leczenia w szpitalu83. Objawy odwodnienia obejmują84:
- Nadmierne pragnienie lub suchość w ustach
- Zmniejszone oddawanie moczu
- Suchość skóry
- Zapadnięte oczy lub policzki
- Brak łez podczas płaczu (u dzieci)
- Wyczerpanie i apatia
Uszkodzenie przewodu pokarmowego
Kwas żołądkowy, który wydobywa się wraz z wymiocinami, może uszkodzić przewód łączący usta i żołądek (przełyk). Czasami przełyk staje się tak podrażniony, że krwawi86. Mogą wystąpić małe pęknięcia w błonie śluzowej przełyku (pęknięcie Mallory’ego-Weissa)87.
Próchnica zębów
Kwas w wymiocinach może powodować korozję szkliwa zębów88, prowadząc do zwiększonego ryzyka próchnicy.
Wpływ na jakość życia
CVS może znacząco wpływać na jakość życia pacjenta89:
- Dzieci mogą opuszczać średnio 24 dni szkoły rocznie i często potrzebują nauczania domowego90
- Dorośli mogą mieć trudności z uczęszczaniem do pracy91
- Ciężkość i nieprzewidywalność objawów utrudnia niektórym pacjentom uczęszczanie do szkoły lub pracy92
- W jednym badaniu stwierdzono, że 32% pacjentów z CVS było całkowicie niepełnosprawnych z powodu swojego stanu93
- Średni roczny koszt badań, leczenia i nieobecności wynosi 17 000 dolarów94
Schorzenia współistniejące
CVS jest związany z różnymi chorobami współistniejącymi, które mogą dodatkowo pogarszać jakość życia95:
- Migrena – około 70% pacjentów z CVS zgłasza osobistą lub rodzinną historię migreny96
- Lęk i depresja – dotyka prawie połowę pacjentów z CVS97
- Zaburzenia autonomiczne98
- Zaburzenia trawienne, takie jak refluks żołądkowo-przełykowy i zespół jelita drażliwego99
- Omdlenia100
Przebieg choroby i rokowanie
Przebieg i rokowanie w zespole wymiotów cyklicznych mogą być zróżnicowane w zależności od pacjenta101:
Czas trwania choroby
CVS może trwać od kilku miesięcy do wielu lat, a nawet dekad102. Większość opublikowanych serii wskazuje, że CVS trwa średnio od 2,5 do 5,5 roku, ustępując w późnym dzieciństwie lub wczesnej adolescencji103.
Progresja choroby
Bez właściwego leczenia epizody CVS mogą z czasem ulec pogorszeniu – mogą występować częściej, a fazy między epizodami mogą się skracać104. Progresja ta, nazywana koalescencją, może utrudniać diagnozę i sugerować bardziej przewlekłą jednostkę chorobową, taką jak gastropareza105.
Rokowanie u dzieci
Większość dzieci z czasem wyrasta z CVS, zazwyczaj około okresu dojrzewania106107. Jednak około 75% z nich prawdopodobnie rozwinie bóle migrenowe w późniejszym życiu108. Niektóre dzieci mogą rozwinąć przewlekłe codzienne nudności109.
Rokowanie u dorosłych
U dorosłych CVS może być bardziej uporczywe, a kilku pacjentów nadal ma objawy przez całe dorosłe życie110. Niektórzy seniorzy z CVS wyrastają z wymiotów i zamiast tego rozwijają epizody bólów migrenowych111.
Chociaż CVS może być schorzeniem przewlekłym, większość pacjentów dobrze odpowiada na leczenie, a rokowanie jest korzystne u większości pacjentów112. Ważne jest jednak, aby pamiętać, że CVS może być chorobą potencjalnie odwracalną: po początkowym intensywnym leczeniu w celu osiągnięcia remisji i po skutecznym leczeniu chorób współistniejących, dawka amitryptyliny może być powoli zmniejszana, a nawet odstawiona z czasem113.
Szczególne cechy CVS u dzieci i dorosłych
Istnieją pewne różnice w manifestacji CVS u dzieci i dorosłych114:
CVS u dzieci
U dzieci CVS najczęściej występuje w wieku 3-7 lat115. Dzieci z CVS często doświadczają epizodów przez kilka godzin lub dni116. Badanie Abu-Arafeh i wsp. wykazało, że średni wiek dzieci z CVS, migrenami brzusznymi i bólami migrenowymi głowy wynosił odpowiednio 5,3 roku, 10,3 roku i 11,5 roku. To odkrycie potwierdza rozwojową progresję od wymiotów do bólu brzucha do bólu głowy117.
Dzieci mogą opuszczać średnio 24 dni szkoły rocznie i często potrzebują nauczania domowego118. Większość dzieci wyrasta z CVS około okresu dojrzewania, ale około 75% prawdopodobnie rozwinie bóle migrenowe w późniejszym życiu119.
CVS u dorosłych
U dorosłych CVS może być bardziej przewlekłe i oporne na leczenie120. Dorośli zazwyczaj mają mniej częste epizody, jednak cykl epizodów może trwać dłużej – około tygodnia121.
U dorosłych występuje znaczna zachorowalność związana z CVS, być może z powodu braku świadomości i wynikających z tego opóźnień w diagnozie. W badaniu 41 pacjentów z CVS, Fleisher stwierdził, że 32% było całkowicie niepełnosprawnych w momencie diagnozy122.
Dorośli pacjenci z CVS często otrzymują fragmentaryczną opiekę, a opóźnienie diagnostyczne od pięciu do sześciu lat od początku objawów jest typowe. Pacjenci często pozostają niezdiagnozowani przez jakiś czas z powodu braku rozpoznania tej jednostki klinicznej, z raportami sugerującymi opóźnienie w diagnozie nawet o 8-21 lat po wystąpieniu objawów123124.
Zespół wymiotów cyklicznych Plus
Niektórzy pacjenci z CVS mają dodatkowe cechy, które określa się mianem zespołu wymiotów cyklicznych plus (CVS plus)125:
- Większość osób z CVS ma normalną inteligencję, chociaż niektóre dotknięte osoby mają opóźnienie rozwojowe lub niepełnosprawność intelektualną
- Zaburzenia ze spektrum autyzmu, które wpływają na komunikację i interakcje społeczne, również były związane z CVS
- Możliwe jest również osłabienie mięśni (miopatia) i napady padaczkowe
Pacjenci z rozpoznaniem zespołu wymiotów cyklicznych plus mają rokowanie zazwyczaj w zakresie od umiarkowanego do złego127.
Związek z migreną
Zespół wymiotów cyklicznych jest często uważany za wariant migren, które są silnymi bólami głowy często związanymi z bólem, nudnościami, wymiotami i skrajną wrażliwością na światło i dźwięk128. CVS jest prawdopodobnie taki sam lub ściśle powiązany ze stanem zwanym migreną brzuszną, który charakteryzuje się atakami bólu brzucha i skurczami129.
Ataki nudności, wymiotów lub bólu brzucha w dzieciństwie mogą być zastąpione przez bóle migrenowe, gdy dotknięta osoba dorasta130. Wielu ludzi z zespołem wymiotów cyklicznych lub migreną brzuszną ma rodzinną historię migren131.
Pojęcia zespołu wymiotów cyklicznych i migreny brzusznej były często używane zamiennie ze względu na znaczące nakładanie się kryteriów klinicznych132. Ponieważ 80% dzieci z CVS ma ból brzucha, a 50% tych z bólem brzucha wymiotuje, wiele dzieci można zdiagnozować zarówno z CVS, jak i z migreną brzuszną133.
CVS ma wiele cech wspólnych z migreną, epilepsją i zaburzeniami paniki134. Te podobieństwa sugerują wspólną neurogenną etiologię i, co więcej, sugerują, że pacjenci z CVS mogliby skorzystać z prób terapii, które są obecnie dostępne w leczeniu migren, napadów padaczkowych lub zaburzeń paniki135.
Podsumowanie
Zespół wymiotów cyklicznych to rzadkie, ale poważne schorzenie charakteryzujące się nawracającymi epizodami intensywnych nudności i wymiotów, które występują cyklicznie i przeplatają się z okresami całkowitego zdrowia. Epizody mają stereotypowy charakter – zaczynają się o podobnej porze dnia, trwają podobny czas i przebiegają z podobnymi objawami o zbliżonym nasileniu136137.
Przebieg choroby obejmuje cztery fazy: prodromalną (ostrzegawczą), fazę wymiotną, fazę zdrowienia i fazę międzynapadową (bez objawów)138139. Główne objawy podczas epizodu to intensywne nudności, wymioty (nawet do 20 razy na godzinę), ból brzucha, objawy autonomiczne (pocenie się, bladość), objawy neurologiczne (ból głowy, nadwrażliwość na światło i dźwięk) oraz zmęczenie140.
Epizody mogą być wyzwalane przez różne czynniki, takie jak infekcje, stres, nadmierne podekscytowanie, głodówka, brak snu czy miesiączka141. CVS może prowadzić do poważnych powikłań, w tym odwodnienia, uszkodzenia przełyku i próchnicy zębów142.
Większość dzieci wyrasta z CVS około okresu dojrzewania, ale około 75% z nich rozwija migreny w późniejszym życiu143. U dorosłych CVS może być bardziej przewlekłe i powodować znaczną niepełnosprawność144.
Zespół wymiotów cyklicznych jest często uważany za wariant migren i ma podobne cechy do migreny brzusznej145. Chociaż nie ma lekarstwa na CVS, większość pacjentów dobrze odpowiada na leczenie, a rokowanie jest korzystne146.
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Materiały źródłowe
- #1 Cyclic vomiting syndrome | UM Health-Sparrowhttps://www.uofmhealthsparrow.org/departments-conditions/conditions/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is characterized by episodes of severe vomiting that have no apparent cause. Episodes can last for hours or days and alternate with symptom-free periods. Episodes are similar, meaning that they tend to start at the same time of day, last the same length of time, and occur with the same symptoms and intensity. […] The symptoms of cyclic vomiting syndrome often begin in the morning. Signs and symptoms include: Three or more recurrent episodes of vomiting that start around the same time and last for a similar length of time. Varying intervals of generally normal health without nausea between episodes. Intense nausea and sweating before an episode starts. […] Other signs and symptoms during a vomiting episode may include: Abdominal pain, Diarrhea, Dizziness, Sensitivity to light, Headache, Retching or gagging.
- #2 Symptoms & Causes of Cyclic Vomiting Syndrome – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/cyclic-vomiting-syndrome/symptoms-causes
The main symptoms of cyclic vomiting syndrome are sudden, repeated attacks called episodes of severe nausea and vomiting. You may vomit several times an hour. Episodes can last from a few hours to several days. Episodes may make you feel very tired and drowsy. […] Each episode of cyclic vomiting syndrome tends to start at the same time of day, last the same length of time, and happen with the same symptoms and intensity as previous episodes. Episodes may begin at any time but often start during the early morning hours. […] Other symptoms of cyclic vomiting syndrome may include one or more of the following: retching trying to vomit but having nothing come out of your mouth, also called dry vomiting, pain in the abdomen, abnormal drowsiness, pale skin, headaches, lack of appetite, not wanting to talk, drooling or spitting, extreme thirst, sensitivity to light or sound, dizziness, diarrhea, fever.
- #3 Cyclic Vomiting Syndrome: Symptoms, Causes & Triggers, Treatmenthttps://my.clevelandclinic.org/health/diseases/14894-cyclic-vomiting-syndrome
Cyclic vomiting syndrome is when you experience cycles of severe nausea, vomiting and exhaustion that can last from a few hours up to a few days. Episodes can last from a few hours to several days. They can be so severe that you need to stay in bed. You may need to go to the emergency room (ER) or hospital to get IV fluids to prevent dehydration. […] CVS may last for months, years or decades. However, symptoms dont occur every day. Episodes generally occur several times a year but can happen up to once or twice a month. […] The symptoms, time of day, frequency, severity and length of each episode are usually the same for any one person. But these factors can vary from person to person. […] Cyclic vomiting syndrome (CVS) involves sudden, repeated episodes of severe nausea and vomiting.
- #4https://www.amerikanhastanesi.org/mayo-clinic-care-network/mayo-clinic-health-information-library/diseases-conditions/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is characterized by episodes of severe vomiting that have no apparent cause. Episodes can last for hours or days and alternate with symptom-free periods. Episodes are similar, meaning that they tend to start at the same time of day, last the same length of time, and occur with the same symptoms and intensity. […] Cyclic vomiting syndrome occurs in all age groups, though it often begins in children around 3 to 7 years old. Although it’s more common in children, the number of cases diagnosed in adults is increasing. […] The symptoms of cyclic vomiting syndrome often begin in the morning. Signs and symptoms include: Three or more recurrent episodes of vomiting that start around the same time and last for a similar length of time. Varying intervals of generally normal health without nausea between episodes. Intense nausea and sweating before an episode starts.
- #5 Cyclic vomiting syndrome | Beacon Health Systemhttps://www.beaconhealthsystem.org/library/diseases-and-conditions/cyclic-vomiting-syndrome?content_id=CON-20166938
Cyclic vomiting syndrome often starts in childhood and is marked by spells of vomiting several times an hour over a period of hours or days. […] Cyclic vomiting syndrome is characterized by episodes of severe vomiting that have no apparent cause. Episodes can last for hours or days and alternate with symptom-free periods. Episodes are similar, meaning that they tend to start at the same time of day, last the same length of time, and occur with the same symptoms and intensity. […] The symptoms of cyclic vomiting syndrome often begin in the morning. Signs and symptoms include: Three or more recurrent episodes of vomiting that start around the same time and last for a similar length of time. Varying intervals of generally normal health without nausea between episodes. Intense nausea and sweating before an episode starts.
- #6 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
If the condition is not treated, episodes usually occur four to 12 times per year. Between attacks, vomiting is absent, and nausea is either absent or much reduced. However, many affected people experience other symptoms during and between episodes, including pain, lethargy, digestive disorders such as gastroesophageal reflux and irritable bowel syndrome, and fainting spells (syncope). People with cyclic vomiting syndrome are also more likely than people without the disorder to experience depression, anxiety, and panic disorder. It is unclear whether these health conditions are directly related to nausea and vomiting. […] Cyclic vomiting syndrome is often considered to be a variant of migraines, which are severe headaches often associated with pain, nausea, vomiting, and extreme sensitivity to light and sound. Cyclic vomiting syndrome is likely the same as or closely related to a condition called abdominal migraine, which is characterized by attacks of stomach pain and cramping. Attacks of nausea, vomiting, or abdominal pain in childhood may be replaced by migraine headaches as an affected person gets older. Many people with cyclic vomiting syndrome or abdominal migraine have a family history of migraines.
- #7 FAQ: Cyclic Vomiting Syndrome | Ohio State Health & Discoveryhttps://health.osu.edu/health/general-health/faq-cyclic-vomiting-syndrome
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) characterized by recurrent episodes of severe nausea, vomiting and often abdominal pain. It can be accompanied by other symptoms, such as excessive sweating, hot and cold flashes, diarrhea and sometimes headaches. […] CVS begins abruptly and usually occurs out of the blue, lasting hours to several days or even a week. In between episodes, individuals have periods of normal health, without any symptoms or can have some nausea and occasional abdominal discomfort at baseline. These symptom-free intervals can last for weeks to months. […] However, if left untreated, people with CVS may experience longer and more frequent episodes, potentially leading to a condition called coalescent CVS, in which the typical normal or inter-episodic phase is lost.
- #8 Cyclical Vomiting Syndrome: Symptoms and Treatment | Doctorhttps://patient.info/doctor/cyclical-vomiting-syndrome-pro
Cyclical vomiting syndrome (CVS) is a condition in which there are repeated episodes of severe nausea, vomiting and physical exhaustion. This condition can be very disruptive and frightening for the individual and also for their families. […] The main symptoms are severe nausea and sudden vomiting which can last from a few hours to a few days. […] There are four phases of the cycle – prodromal, vomiting, recovery and well phases. […] The prodromal phase can often be marked by intense sweating and nausea. The person may also look very pale. This phase generally lasts from a few minutes to several hours. […] The vomiting phase then follows which can last from hours to days. Nausea, vomiting and retching last for 20 to 30 minutes at a time. […] The recovery phase begins with cessation of vomiting and retching, improving appetite and return of energy.
- #9 Symptoms & Causes of Cyclic Vomiting Syndrome – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/cyclic-vomiting-syndrome/symptoms-causes
The symptoms will vary as you go through the four phases of cyclic vomiting syndrome: During the prodrome phase, you feel an episode coming on. Often marked by intense sweating and nausea with or without pain in your abdomen this phase can last from a few minutes to several hours. Your skin may look unusually pale. […] The main symptoms of this phase are severe nausea, vomiting, and retching. At the peak of this phase, you may vomit several times an hour. […] Recovery begins when you stop vomiting and retching and you feel less nauseated. You may feel better gradually or quickly. The recovery phase ends when your nausea stops and your healthy skin color, appetite, and energy return. […] The well phase happens between episodes. You have no symptoms during this phase.
- #10 Cyclic vomiting syndrome – Wikipediahttps://en.wikipedia.org/wiki/Cyclic_vomiting_syndrome
Episodes may happen every few days, every few weeks or every few months, for some happening at common uniform times, typically mornings. For other affected people, there is not a pattern in time that can be recognized. Some with the condition have a warning of an episodic attack; they may experience a prodrome, some documented prodromal symptoms include: unusually intense nausea and pallor, excess salivation, sweating, flushing, rapid/irregular heartbeat, diarrhea, anxiety/panic, food aversion, restlessness/insomnia, irritability, depersonalization, fatigue/listlessness, intense feelings of being hot or chilled, intense thirst, shivering/shaking, retching, tachypnea, abdominal pain/cramping, limb paresthesias, hyperesthesia, photophobia, phonophobia, headache, and dyspnea, heightened sensitivity, especially to light, though sensitivity to smell, sound, pressure, and temperature, as well as oncoming muscle pain and fatigue, are also reported by some patients. Many experience a full panic attack when nausea begins and continue to panic once the vomiting has begun.
- #11 Cyclical Vomiting Syndrome: Symptoms and Treatment | Doctorhttps://patient.info/doctor/cyclical-vomiting-syndrome-pro
Cyclical vomiting syndrome (CVS) is a condition in which there are repeated episodes of severe nausea, vomiting and physical exhaustion. This condition can be very disruptive and frightening for the individual and also for their families. […] The main symptoms are severe nausea and sudden vomiting which can last from a few hours to a few days. […] There are four phases of the cycle – prodromal, vomiting, recovery and well phases. […] The prodromal phase can often be marked by intense sweating and nausea. The person may also look very pale. This phase generally lasts from a few minutes to several hours. […] The vomiting phase then follows which can last from hours to days. Nausea, vomiting and retching last for 20 to 30 minutes at a time. […] The recovery phase begins with cessation of vomiting and retching, improving appetite and return of energy.
- #12 Cyclic vomiting syndrome: From pathophysiology to treatment | Revista de GastroenterologÃa de Méxicohttps://www.revistagastroenterologiamexico.org/en-cyclic-vomiting-syndrome-from-pathophysiology-articulo-S2255534X24000616
Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent and unpredictable episodes of intense vomiting, interspersed with periods of apparent wellbeing. […] Vomiting episodes tend to be incapacitating, negatively impacting quality of life. […] CVS has significant diagnostic challenges, given that there is no specific test for confirming its presence. […] Management of CVS typically involves a multidisciplinary approach. […] The prodrome phase precedes the emetic phase and is reported in approximately 61-93% of adult patients. Symptoms can include nausea, abdominal pain, and multiple autonomic symptoms, such as diaphoresis, intolerance to cold and heat, sialorrhea, pallor, and lethargy. […] The emetic phase is characterized by severe and incessant vomiting and retching.
- #13 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) and is characterized by recurrent episodes of severe nausea, vomiting, and often, abdominal pain. Patients are usually asymptomatic in between episodes. […] Most patients (~ 93%) have a prodromal phase. Symptoms during this phase can include nausea, abdominal pain, diaphoresis, fatigue, weakness, hot flashes, chills, shivering, increased thirst, loss of appetite, burping, lightheadedness, and paresthesia. Some patients report a sense of impending doom and many have symptoms consistent with panic. If untreated, this progresses to the emetic phase and patients have unrelenting nausea, retching, vomiting, and other symptoms. During an episode, patients may vomit up to 20 times per hour and the episode may last several hours to days. During this phase, patients are sometimes described as being in a âconscious comaâ and exhibit lethargy, listlessness, withdrawal, and sometimes disorientation.
- #14 Cyclic Vomiting Syndrome: Recognition and Guidelines for Treatment | UPMC Physician Resourceshttps://www.upmcphysicianresources.com/news/011822-cyclic-vomiting-syndrome
Nausea and vomiting have many etiologies, and cyclic vomiting syndrome (CVS) is not the first diagnosis that comes to mind for an adult presenting to the emergency department. […] Adults with CVS almost always receive fragmented care, and a diagnostic delay of five to six years from the onset of symptoms is typical. […] CVS is characterized by four phases. Each attack begins with a prodromic phase, followed by an emetic phase, and then a recovery phase. Between episodes, there is a well phase, during which the patient is typically, but not always, asymptomatic. […] Sweating and nausea are common during the prodrome phase, which is similar to the prodrome experienced by migraine sufferers. […] Episodes often begin suddenly in the early morning. Patients describe this sudden onset as feeling like a switch flipped, which suggests a nervous system state change.
- #15 Symptoms & Causes of Cyclic Vomiting Syndrome – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/cyclic-vomiting-syndrome/symptoms-causes
The symptoms will vary as you go through the four phases of cyclic vomiting syndrome: During the prodrome phase, you feel an episode coming on. Often marked by intense sweating and nausea with or without pain in your abdomen this phase can last from a few minutes to several hours. Your skin may look unusually pale. […] The main symptoms of this phase are severe nausea, vomiting, and retching. At the peak of this phase, you may vomit several times an hour. […] Recovery begins when you stop vomiting and retching and you feel less nauseated. You may feel better gradually or quickly. The recovery phase ends when your nausea stops and your healthy skin color, appetite, and energy return. […] The well phase happens between episodes. You have no symptoms during this phase.
- #16 Cyclic Vomiting Syndrome â CVS | Ohio State Medical Centerhttps://wexnermedical.osu.edu/digestive-diseases/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is a chronic disease marked by severe and recurrent episodes of nausea and vomiting that occur every 10 minutes for several hours. […] During a CVS episode, vomiting can be severe and may occur as often as every 10 minutes for several hours. […] CVS is marked by severe and recurrent episodes of vomiting. During an attack, vomiting may occur every five to 10 minutes for several hours. In general, most episodes last three to seven days. Episodes often start in the middle of the night or early morning hours. […] Other symptoms during an episode can include: Severe nausea, Severe stomach pain, Tiredness, Sensitivity to light, Headaches.
- #17 Cyclic Vomiting Syndrome â CVS | Ohio State Medical Centerhttps://wexnermedical.osu.edu/digestive-diseases/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is a chronic disease marked by severe and recurrent episodes of nausea and vomiting that occur every 10 minutes for several hours. […] During a CVS episode, vomiting can be severe and may occur as often as every 10 minutes for several hours. […] CVS is marked by severe and recurrent episodes of vomiting. During an attack, vomiting may occur every five to 10 minutes for several hours. In general, most episodes last three to seven days. Episodes often start in the middle of the night or early morning hours. […] Other symptoms during an episode can include: Severe nausea, Severe stomach pain, Tiredness, Sensitivity to light, Headaches.
- #18 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age. […] The episodes of nausea, vomiting, and lethargy last anywhere from an hour to 10 days. An affected person may vomit several times per hour, potentially leading to a dangerous loss of fluids (dehydration). Additional symptoms can include unusually pale skin (pallor), abdominal pain, diarrhea, headache, fever, and an increased sensitivity to light (photophobia) or to sound (phonophobia). In most affected people, the signs and symptoms of each attack are quite similar. These attacks can be debilitating, making it difficult for an affected person to go to work or school. […] Episodes of nausea, vomiting, and lethargy can occur regularly or apparently at random, or can be triggered by a variety of factors. The most common triggers are emotional excitement and infections. Other triggers can include periods without eating (fasting), temperature extremes, lack of sleep, overexertion, allergies, ingesting certain foods or alcohol, and menstruation.
- #19 Cyclic Vomiting Syndrome â CVS | Ohio State Medical Centerhttps://wexnermedical.osu.edu/digestive-diseases/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is a chronic disease marked by severe and recurrent episodes of nausea and vomiting that occur every 10 minutes for several hours. […] During a CVS episode, vomiting can be severe and may occur as often as every 10 minutes for several hours. […] CVS is marked by severe and recurrent episodes of vomiting. During an attack, vomiting may occur every five to 10 minutes for several hours. In general, most episodes last three to seven days. Episodes often start in the middle of the night or early morning hours. […] Other symptoms during an episode can include: Severe nausea, Severe stomach pain, Tiredness, Sensitivity to light, Headaches.
- #20 Cyclic Vomiting Syndrome | Children’s Hospital of Philadelphiahttps://www.chop.edu/conditions-diseases/cyclic-vomiting
Cyclic vomiting syndrome (CVS) is a condition that involves recurrent episodes of vomiting with three main features: sudden onset, stereotypical (similar episodes), and periods of wellness between episodes. […] CVS symptoms include vomiting episodes that recur in a cyclical pattern (for example every two weeks or once a month). The vomiting episodes start suddenly, typically beginning with nausea, and progress to vomiting later. The episodes can sometimes wake the affected person from sleep. […] The episodes are stereotypical which means that each new episode resembles previous episodes. Other symptoms can include stomach pain, diarrhea and headache. The vomiting attacks can become so severe that patients become dehydrated and require medical attention. […] In between episodes, patients generally feel completely well. Once an episode resolves, affected children often feel normal within hours. […] Once patients are properly diagnosed and treated, most improve. Additionally, many children outgrow the diagnosis before adulthood.
- #21 Cyclic vomiting syndrome: From pathophysiology to treatment | Revista de GastroenterologÃa de Méxicohttps://www.revistagastroenterologiamexico.org/en-cyclic-vomiting-syndrome-from-pathophysiology-articulo-S2255534X24000616
Once the vomiting has ceased, patients slowly tolerate oral intake before returning to their normal routine. […] The frequency of CVS episodes varies from every two-to-three weeks to three times a year. Episode duration can vary from hours to several days. […] The clinical history is essential in the diagnosis of CVS, which is characterized by episodes of incoercible vomiting, alternating with periods of few or no symptoms. […] The definitive diagnosis is currently made in patients that meet the Rome criteria and in whom other causes of emesis have been ruled out through a detailed clinical history and the previously mentioned tests. […] It is necessary to avoid the triggers identified by the patient (insomnia, fasting, stress). […] Given that chronic cannabis consumption is associated with the lack of treatment response, its use should be suspended.
- #22 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic of CVS. […] Although periods of complete normality typically occur between episodes, many adult patients lose the cyclic pattern of symptoms over time, and 63% of them develop inter episodic symptoms (often nausea) between episodes; this pattern is termed coalescence. […] The vomiting in CVS is typically much more severe and intermittent than that observed in gastroesophageal reflux. […] The stereotypical on-off pattern often begins with a prodrome of nausea and pallor. Vomiting peaks in the first hour and then begins to decline over the ensuing 4-8 hours, lasting a mean of 24 hours (median, 43 hours).
- #23 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Besides vomiting, patients may also experience other GI symptoms. Abdominal pain is present in 80% of patients and may initially be severe enough to mimic acute abdomen and result in a laparotomy. […] Most patients experience retching (79%) and nausea (82%). They typically describe the nausea as the most distressing symptom: It is unrelenting, is completely unrelieved by vomiting, and disappears only when the child is asleep or the episode is over. […] Fever, diarrhea, or both are noted in approximately one third of CVS patients, complicating the differentiation of this condition from gastroenteritis. […] Many patients with CVS have neurologic symptoms, which support the relation between migraines and CVS. Symptoms include headache (42%), photophobia (38%), phonophobia (30%), and vertigo (26%).
- #24 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) and is characterized by recurrent episodes of severe nausea, vomiting, and often, abdominal pain. Patients are usually asymptomatic in between episodes. […] Most patients (~ 93%) have a prodromal phase. Symptoms during this phase can include nausea, abdominal pain, diaphoresis, fatigue, weakness, hot flashes, chills, shivering, increased thirst, loss of appetite, burping, lightheadedness, and paresthesia. Some patients report a sense of impending doom and many have symptoms consistent with panic. If untreated, this progresses to the emetic phase and patients have unrelenting nausea, retching, vomiting, and other symptoms. During an episode, patients may vomit up to 20 times per hour and the episode may last several hours to days. During this phase, patients are sometimes described as being in a âconscious comaâ and exhibit lethargy, listlessness, withdrawal, and sometimes disorientation.
- #25 Symptoms & Causes of Cyclic Vomiting Syndrome – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/cyclic-vomiting-syndrome/symptoms-causes
The symptoms will vary as you go through the four phases of cyclic vomiting syndrome: During the prodrome phase, you feel an episode coming on. Often marked by intense sweating and nausea with or without pain in your abdomen this phase can last from a few minutes to several hours. Your skin may look unusually pale. […] The main symptoms of this phase are severe nausea, vomiting, and retching. At the peak of this phase, you may vomit several times an hour. […] Recovery begins when you stop vomiting and retching and you feel less nauseated. You may feel better gradually or quickly. The recovery phase ends when your nausea stops and your healthy skin color, appetite, and energy return. […] The well phase happens between episodes. You have no symptoms during this phase.
- #26 Cyclic vomiting syndrome: From pathophysiology to treatment | Revista de GastroenterologÃa de Méxicohttps://www.revistagastroenterologiamexico.org/en-cyclic-vomiting-syndrome-from-pathophysiology-articulo-S2255534X24000616
Once the vomiting has ceased, patients slowly tolerate oral intake before returning to their normal routine. […] The frequency of CVS episodes varies from every two-to-three weeks to three times a year. Episode duration can vary from hours to several days. […] The clinical history is essential in the diagnosis of CVS, which is characterized by episodes of incoercible vomiting, alternating with periods of few or no symptoms. […] The definitive diagnosis is currently made in patients that meet the Rome criteria and in whom other causes of emesis have been ruled out through a detailed clinical history and the previously mentioned tests. […] It is necessary to avoid the triggers identified by the patient (insomnia, fasting, stress). […] Given that chronic cannabis consumption is associated with the lack of treatment response, its use should be suspended.
- #27 Cyclic Vomiting Syndrome in 41 adults: the illness, the patients, and problems of management | BMC Medicine | Full Texthttps://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-3-20
The emetic phase was characterized by persistence of many prodromal symptoms plus severe, persistent nausea and vomiting. […] The deterioration of CVS took the form of near- or complete coalescence of episodes. A near-coalescence occurs when episodes recur with increasing frequency. […] The typical length of the recovery phase was reported by 22 patients and ranged from minutes to as much as ten days.
- #28 Symptoms & Causes of Cyclic Vomiting Syndrome – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/cyclic-vomiting-syndrome/symptoms-causes
The symptoms will vary as you go through the four phases of cyclic vomiting syndrome: During the prodrome phase, you feel an episode coming on. Often marked by intense sweating and nausea with or without pain in your abdomen this phase can last from a few minutes to several hours. Your skin may look unusually pale. […] The main symptoms of this phase are severe nausea, vomiting, and retching. At the peak of this phase, you may vomit several times an hour. […] Recovery begins when you stop vomiting and retching and you feel less nauseated. You may feel better gradually or quickly. The recovery phase ends when your nausea stops and your healthy skin color, appetite, and energy return. […] The well phase happens between episodes. You have no symptoms during this phase.
- #29 Cyclic Vomiting Syndrome in Childrenhttps://www.uspharmacist.com/article/cyclic-vomiting-syndrome-in-children
The vomiting episodes usually last for 1 to 3 days. […] The recovery phase begins with the disappearance of nausea and vomiting and lasts until the child resumes normal appetite and activity. Some children may be able to return to eating within a couple of hours, but many will take a few days to return to a regular diet and get their energy back. […] Complications of CVS include severe dehydration, electrolyte imbalances, hematemesis, Mallory-Weiss tear of the esophagus, aspiration, and hypovolemic shock. […] Abdominal pain, diarrhea, fever, dizziness, and sensitivity to light often accompany the vomiting during acute episodes. […] Immediate treatment of vomiting attacks is crucial, since the physical stress of the episode predisposes the patient to more vomiting and perpetuates the cycle.
- #30 Symptoms & Causes of Cyclic Vomiting Syndrome – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/cyclic-vomiting-syndrome/symptoms-causes
The symptoms will vary as you go through the four phases of cyclic vomiting syndrome: During the prodrome phase, you feel an episode coming on. Often marked by intense sweating and nausea with or without pain in your abdomen this phase can last from a few minutes to several hours. Your skin may look unusually pale. […] The main symptoms of this phase are severe nausea, vomiting, and retching. At the peak of this phase, you may vomit several times an hour. […] Recovery begins when you stop vomiting and retching and you feel less nauseated. You may feel better gradually or quickly. The recovery phase ends when your nausea stops and your healthy skin color, appetite, and energy return. […] The well phase happens between episodes. You have no symptoms during this phase.
- #31 CVS in Adults – About GI Motilityhttps://aboutgimotility.org/learn-about-gi-motility/disorders-of-the-stomach/cyclic-vomiting-syndrome/cvs-in-adults/
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) diagnosed by clinical criteria called Rome criteria as there are no biomarkers (blood tests or x-ray tests) that can be used to detect this condition. CVS includes stereotypic episodes of severe nausea and vomiting that can last from a few hours up to a week. Other symptoms include abdominal pain, feelings of panic, feeling hot and cold, sweats and diarrhea. […] The symptom episodes of CVS tend to follow the same pattern for each individual patient over time. The symptom episodes are characterized by four phases: prodromal phase- During this phase, the patient may experience intense sweating and nausea or feel like an episode of vomiting is about to start. emetic (vomiting phase)- This phase is characterized by intense, persistent nausea, vomiting, and other symptoms (abdominal pain, prostration, and lethargy). This phase lasts from hours to days. recovery phase- This phase begins with the settling down of nausea and ends when hunger, tolerance of oral intake, and vigor return to normal. inter-episodic phase- This phase occurs between vomiting episodes when the patient is relatively symptom-free. This phase typically lasts weeks to months. […] Though many patients return to normal health in between episodes, some patients continue to experience mild nausea and/or abdominal pain in between episodes.
- #32 Understanding Cyclic Vomiting Syndrome (CVS) | Saint Luke’s Health Systemhttps://www.saintlukeskc.org/health-library/understanding-cyclic-vomiting-syndrome-cvs
Cyclic vomiting syndrome (CVS) is an uncommon health problem in adults. It occurs when you have sudden, recurring episodes or attacks of vomiting. The main symptom of CVS is sudden, recurring episodes of vomiting. They may occur several times a month or several times a year. The episodes follow a similar pattern every time you have them. They tend to start at the same time and last about the same amount of time (hours to days). The pattern is unique to you. Between episodes, you won’t have any nausea or vomiting. […] You may have these other symptoms during an attack: Stomach pain, Heaving, Fever, Loss of appetite, Dizziness, Sensitivity to light, Sluggishness, Diarrhea. Some people with CVS find that symptoms start after a certain trigger. Triggers may include stress, a lack of sleep, substance use, an infection, and certain foods like chocolate or cheese. In women, the syndrome may happen at the same time as their menstrual period.
- #33 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Patients are usually asymptomatic between episodes but ~ 30% can have interepisodic nausea and dyspepsia. In some patients, episodes become progressively longer and the interepisodic phase is considerably shortened and patients have a âcoalescence of symptoms.â […] The severity and unpredictable nature of symptoms makes it difficult for some patients to attend school or work; one study found that 32% of patients with CVS were completely disabled. […] CVS is associated with various comorbidities such as migraine, anxiety, depression and dysautonomia, which can further impair quality of life. Approximately 70% of CVS patients report a personal or family history of migraine. Anxiety and depression affects nearly half of patients with CVS.
- #34 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic of CVS. […] Although periods of complete normality typically occur between episodes, many adult patients lose the cyclic pattern of symptoms over time, and 63% of them develop inter episodic symptoms (often nausea) between episodes; this pattern is termed coalescence. […] The vomiting in CVS is typically much more severe and intermittent than that observed in gastroesophageal reflux. […] The stereotypical on-off pattern often begins with a prodrome of nausea and pallor. Vomiting peaks in the first hour and then begins to decline over the ensuing 4-8 hours, lasting a mean of 24 hours (median, 43 hours).
- #35 Cyclic vomiting syndrome: From pathophysiology to treatment | Revista de GastroenterologÃa de Méxicohttps://www.revistagastroenterologiamexico.org/en-cyclic-vomiting-syndrome-from-pathophysiology-articulo-S2255534X24000616
Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent and unpredictable episodes of intense vomiting, interspersed with periods of apparent wellbeing. […] Vomiting episodes tend to be incapacitating, negatively impacting quality of life. […] CVS has significant diagnostic challenges, given that there is no specific test for confirming its presence. […] Management of CVS typically involves a multidisciplinary approach. […] The prodrome phase precedes the emetic phase and is reported in approximately 61-93% of adult patients. Symptoms can include nausea, abdominal pain, and multiple autonomic symptoms, such as diaphoresis, intolerance to cold and heat, sialorrhea, pallor, and lethargy. […] The emetic phase is characterized by severe and incessant vomiting and retching.
- #36 Symptoms & Causes of Cyclic Vomiting Syndrome – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/cyclic-vomiting-syndrome/symptoms-causes
The main symptoms of cyclic vomiting syndrome are sudden, repeated attacks called episodes of severe nausea and vomiting. You may vomit several times an hour. Episodes can last from a few hours to several days. Episodes may make you feel very tired and drowsy. […] Each episode of cyclic vomiting syndrome tends to start at the same time of day, last the same length of time, and happen with the same symptoms and intensity as previous episodes. Episodes may begin at any time but often start during the early morning hours. […] Other symptoms of cyclic vomiting syndrome may include one or more of the following: retching trying to vomit but having nothing come out of your mouth, also called dry vomiting, pain in the abdomen, abnormal drowsiness, pale skin, headaches, lack of appetite, not wanting to talk, drooling or spitting, extreme thirst, sensitivity to light or sound, dizziness, diarrhea, fever.
- #37 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) and is characterized by recurrent episodes of severe nausea, vomiting, and often, abdominal pain. Patients are usually asymptomatic in between episodes. […] Most patients (~ 93%) have a prodromal phase. Symptoms during this phase can include nausea, abdominal pain, diaphoresis, fatigue, weakness, hot flashes, chills, shivering, increased thirst, loss of appetite, burping, lightheadedness, and paresthesia. Some patients report a sense of impending doom and many have symptoms consistent with panic. If untreated, this progresses to the emetic phase and patients have unrelenting nausea, retching, vomiting, and other symptoms. During an episode, patients may vomit up to 20 times per hour and the episode may last several hours to days. During this phase, patients are sometimes described as being in a âconscious comaâ and exhibit lethargy, listlessness, withdrawal, and sometimes disorientation.
- #38 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Besides vomiting, patients may also experience other GI symptoms. Abdominal pain is present in 80% of patients and may initially be severe enough to mimic acute abdomen and result in a laparotomy. […] Most patients experience retching (79%) and nausea (82%). They typically describe the nausea as the most distressing symptom: It is unrelenting, is completely unrelieved by vomiting, and disappears only when the child is asleep or the episode is over. […] Fever, diarrhea, or both are noted in approximately one third of CVS patients, complicating the differentiation of this condition from gastroenteritis. […] Many patients with CVS have neurologic symptoms, which support the relation between migraines and CVS. Symptoms include headache (42%), photophobia (38%), phonophobia (30%), and vertigo (26%).
- #39 Catamenial Cyclical Vomiting Syndrome: Symptoms and Morehttps://www.healthline.com/health/digestive-health/catamenial-cyclic-vomiting-syndrome
Cyclic vomiting syndrome (CVS) is characterized by episodes of uncontrolled nausea and vomiting. […] These episodes can last for several hours or several days. For some people, these episodes can include additional symptoms such as dizziness, fatigue, paleness, and headaches. […] The most notable symptoms of catamenial CVS are nausea and vomiting during CVS episodes. […] For people with the condition, this nausea can be severe and can make it difficult to leave bed. […] Unlike many other conditions that cause nausea and vomiting, vomiting typically doesn’t relieve nausea for people with CVS. Instead, the nausea commonly persists until the episode ends. […] Other symptoms people with catamenial CVS might experience during an episode include fatigue, dizziness, pallor, headaches, body aches, drooling, dehydration, abdominal pain, diarrhea, sensitivity to light, and sensitivity to sound.
- #40 Symptoms & Causes of Cyclic Vomiting Syndrome – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/cyclic-vomiting-syndrome/symptoms-causes
The main symptoms of cyclic vomiting syndrome are sudden, repeated attacks called episodes of severe nausea and vomiting. You may vomit several times an hour. Episodes can last from a few hours to several days. Episodes may make you feel very tired and drowsy. […] Each episode of cyclic vomiting syndrome tends to start at the same time of day, last the same length of time, and happen with the same symptoms and intensity as previous episodes. Episodes may begin at any time but often start during the early morning hours. […] Other symptoms of cyclic vomiting syndrome may include one or more of the following: retching trying to vomit but having nothing come out of your mouth, also called dry vomiting, pain in the abdomen, abnormal drowsiness, pale skin, headaches, lack of appetite, not wanting to talk, drooling or spitting, extreme thirst, sensitivity to light or sound, dizziness, diarrhea, fever.
- #41 About cyclic vomiting syndrome | Children’s Wisconsinhttps://childrenswi.org/medical-care/gastroenterology-liver-and-nutrition-program/conditions/cyclic-vomiting-syndrome
Relentless vomiting can lead to significant dehydration. Signs of dehydration include thirst, much less urination, a dry mouth, and irritability or difficulty staying awake. A child with symptoms of dehydration should see a health care provider immediately. […] Vomiting can cause severe dehydration that can be life threatening and lead to hospitalization. Cyclic vomiting attacks can last for days and be extremely debilitating for the child and disruptive to family life. On average, these children miss about three weeks of school annually and suffer from significant anxiety due to their condition. […] Many children will outgrow CVS around puberty, but about 75% will likely develop migraine headaches later in life. Some children develop chronic daily nausea.
- #42 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Besides vomiting, patients may also experience other GI symptoms. Abdominal pain is present in 80% of patients and may initially be severe enough to mimic acute abdomen and result in a laparotomy. […] Most patients experience retching (79%) and nausea (82%). They typically describe the nausea as the most distressing symptom: It is unrelenting, is completely unrelieved by vomiting, and disappears only when the child is asleep or the episode is over. […] Fever, diarrhea, or both are noted in approximately one third of CVS patients, complicating the differentiation of this condition from gastroenteritis. […] Many patients with CVS have neurologic symptoms, which support the relation between migraines and CVS. Symptoms include headache (42%), photophobia (38%), phonophobia (30%), and vertigo (26%).
- #43 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Besides vomiting, patients may also experience other GI symptoms. Abdominal pain is present in 80% of patients and may initially be severe enough to mimic acute abdomen and result in a laparotomy. […] Most patients experience retching (79%) and nausea (82%). They typically describe the nausea as the most distressing symptom: It is unrelenting, is completely unrelieved by vomiting, and disappears only when the child is asleep or the episode is over. […] Fever, diarrhea, or both are noted in approximately one third of CVS patients, complicating the differentiation of this condition from gastroenteritis. […] Many patients with CVS have neurologic symptoms, which support the relation between migraines and CVS. Symptoms include headache (42%), photophobia (38%), phonophobia (30%), and vertigo (26%).
- #44 Cyclic Vomiting Syndrome in Childrenhttps://www.rwjbh.org/treatment-care/pediatrics/conditions-treatments/pediatric-gastroenterology/cyclic-vomiting/
Children with cyclic vomiting syndrome experience a range of symptoms, including: […] Severe, ongoing nausea […] Vomiting episodes that last for hours or even days […] Episodes that start overnight or early in the morning […] Belly pain before vomiting starts […] Periods of feeling completely well between episodes […] Each episode is very similar for the child. […] Cyclic vomiting syndrome (CVS) is a condition where children experience periods of intense, unremitting nausea and vomiting that last hours to days. These episodes occur two or more times within a 6-month period. Each episode is similar for the patient and is separated by weeks to months, with the child returning to normal health between episodes. Episodes often start overnight or in the early morning and can be preceded by belly pain. Most vomiting episodes last less than 24 hours and often resolve when the child can sleep.
- #45 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Besides vomiting, patients may also experience other GI symptoms. Abdominal pain is present in 80% of patients and may initially be severe enough to mimic acute abdomen and result in a laparotomy. […] Most patients experience retching (79%) and nausea (82%). They typically describe the nausea as the most distressing symptom: It is unrelenting, is completely unrelieved by vomiting, and disappears only when the child is asleep or the episode is over. […] Fever, diarrhea, or both are noted in approximately one third of CVS patients, complicating the differentiation of this condition from gastroenteritis. […] Many patients with CVS have neurologic symptoms, which support the relation between migraines and CVS. Symptoms include headache (42%), photophobia (38%), phonophobia (30%), and vertigo (26%).
- #46 Cyclic Vomiting Syndrome: Recognition and Guidelines for Treatment | UPMC Physician Resourceshttps://www.upmcphysicianresources.com/news/011822-cyclic-vomiting-syndrome
CVS episodes are typically accompanied by tachycardia, dizziness, salivation, and paleness of the skin. During the emetic phase, the patient experiences severe nausea and vomits or retches repeatedly. Stomach pain may accompany vomiting. The emetic phase can last for hours or days. […] The recovery phase begins when vomiting and retching stop and lasts until normal energy and appetite return. […] Patients with CVS experience multiple episodes of vomiting each year. […] The diagnostic criteria known as the Rome IV criteria define the cyclic nature of CVS as two acute-onset episodes within six months that are at least a week apart and each lasts for less than seven days with an absence of vomiting between episodes. […] CVS has many features in common with migraine, epilepsy, and panic disorder.
- #47 Cyclic vomiting syndrome – Wikipediahttps://en.wikipedia.org/wiki/Cyclic_vomiting_syndrome
Episodes may happen every few days, every few weeks or every few months, for some happening at common uniform times, typically mornings. For other affected people, there is not a pattern in time that can be recognized. Some with the condition have a warning of an episodic attack; they may experience a prodrome, some documented prodromal symptoms include: unusually intense nausea and pallor, excess salivation, sweating, flushing, rapid/irregular heartbeat, diarrhea, anxiety/panic, food aversion, restlessness/insomnia, irritability, depersonalization, fatigue/listlessness, intense feelings of being hot or chilled, intense thirst, shivering/shaking, retching, tachypnea, abdominal pain/cramping, limb paresthesias, hyperesthesia, photophobia, phonophobia, headache, and dyspnea, heightened sensitivity, especially to light, though sensitivity to smell, sound, pressure, and temperature, as well as oncoming muscle pain and fatigue, are also reported by some patients. Many experience a full panic attack when nausea begins and continue to panic once the vomiting has begun.
- #48 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) and is characterized by recurrent episodes of severe nausea, vomiting, and often, abdominal pain. Patients are usually asymptomatic in between episodes. […] Most patients (~ 93%) have a prodromal phase. Symptoms during this phase can include nausea, abdominal pain, diaphoresis, fatigue, weakness, hot flashes, chills, shivering, increased thirst, loss of appetite, burping, lightheadedness, and paresthesia. Some patients report a sense of impending doom and many have symptoms consistent with panic. If untreated, this progresses to the emetic phase and patients have unrelenting nausea, retching, vomiting, and other symptoms. During an episode, patients may vomit up to 20 times per hour and the episode may last several hours to days. During this phase, patients are sometimes described as being in a âconscious comaâ and exhibit lethargy, listlessness, withdrawal, and sometimes disorientation.
- #49 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Besides vomiting, patients may also experience other GI symptoms. Abdominal pain is present in 80% of patients and may initially be severe enough to mimic acute abdomen and result in a laparotomy. […] Most patients experience retching (79%) and nausea (82%). They typically describe the nausea as the most distressing symptom: It is unrelenting, is completely unrelieved by vomiting, and disappears only when the child is asleep or the episode is over. […] Fever, diarrhea, or both are noted in approximately one third of CVS patients, complicating the differentiation of this condition from gastroenteritis. […] Many patients with CVS have neurologic symptoms, which support the relation between migraines and CVS. Symptoms include headache (42%), photophobia (38%), phonophobia (30%), and vertigo (26%).
- #50 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Besides vomiting, patients may also experience other GI symptoms. Abdominal pain is present in 80% of patients and may initially be severe enough to mimic acute abdomen and result in a laparotomy. […] Most patients experience retching (79%) and nausea (82%). They typically describe the nausea as the most distressing symptom: It is unrelenting, is completely unrelieved by vomiting, and disappears only when the child is asleep or the episode is over. […] Fever, diarrhea, or both are noted in approximately one third of CVS patients, complicating the differentiation of this condition from gastroenteritis. […] Many patients with CVS have neurologic symptoms, which support the relation between migraines and CVS. Symptoms include headache (42%), photophobia (38%), phonophobia (30%), and vertigo (26%).
- #51 Cyclic vomiting syndrome – Wikipediahttps://en.wikipedia.org/wiki/Cyclic_vomiting_syndrome
Episodes may happen every few days, every few weeks or every few months, for some happening at common uniform times, typically mornings. For other affected people, there is not a pattern in time that can be recognized. Some with the condition have a warning of an episodic attack; they may experience a prodrome, some documented prodromal symptoms include: unusually intense nausea and pallor, excess salivation, sweating, flushing, rapid/irregular heartbeat, diarrhea, anxiety/panic, food aversion, restlessness/insomnia, irritability, depersonalization, fatigue/listlessness, intense feelings of being hot or chilled, intense thirst, shivering/shaking, retching, tachypnea, abdominal pain/cramping, limb paresthesias, hyperesthesia, photophobia, phonophobia, headache, and dyspnea, heightened sensitivity, especially to light, though sensitivity to smell, sound, pressure, and temperature, as well as oncoming muscle pain and fatigue, are also reported by some patients. Many experience a full panic attack when nausea begins and continue to panic once the vomiting has begun.
- #52 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Besides vomiting, patients may also experience other GI symptoms. Abdominal pain is present in 80% of patients and may initially be severe enough to mimic acute abdomen and result in a laparotomy. […] Most patients experience retching (79%) and nausea (82%). They typically describe the nausea as the most distressing symptom: It is unrelenting, is completely unrelieved by vomiting, and disappears only when the child is asleep or the episode is over. […] Fever, diarrhea, or both are noted in approximately one third of CVS patients, complicating the differentiation of this condition from gastroenteritis. […] Many patients with CVS have neurologic symptoms, which support the relation between migraines and CVS. Symptoms include headache (42%), photophobia (38%), phonophobia (30%), and vertigo (26%).
- #53 Cyclic Vomiting Syndrome in 41 adults: the illness, the patients, and problems of management | BMC Medicine | Full Texthttps://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-3-20/tables/1
Nausea […] Sweating […] Epigastric pain or „pressure” […] Fatigue or weakness […] Feeling hot and/or chilly […] Cramping urge to defecate […] Abdominal pain […] Shivering or shakiness […] Insomnia or restless, interrupted sleep […] Aversion for food […] Pounding or irregular heartbeat […] Irritability […] „Panic feelings” […] Intense thirst […] Feelings of depersonalization […] Headache […] Increased salivation […] Dyspnea […] A sensation of abdominal bloating […] Inability to burp […] Excessive burping […] Inability to effect the desired passage of stool or flatus […] Loose stooling […] Epigastric burning […] Paresthesias […] Light headedness
- #54 Cyclic Vomiting Syndrome Causes, Symptoms, Diet, Treatmenthttps://www.medicinenet.com/cyclic_vomiting_syndrome_cvs/article.htm
Cyclic vomiting syndrome is characterized by attacks of intense nausea, vomiting, and lethargy that last anywhere from an hour to 10 days. A person may vomit several times per hour, potentially leading to a dangerous loss of fluids (dehydration). Additional symptoms can include unusually pale skin (pallor or paleness), abdominal pain, diarrhea, headache, and increased sensitivity to light (photophobia) or to sound (phonophobia). In most affected people, the signs and symptoms of each attack are quite similar. […] A person with cyclic vomiting syndrome may have one or more of these symptoms and signs: Repeated vomiting or retching, Heaving or gagging (dry vomiting), Abdominal pain, Diarrhea, Fever, Dizziness, Pale skin, Sensitivity to light (photophobia), Sensitivity to sound (phonophobia), Headaches, Loss of appetite, Thirst, Reduced or less urination, Motion sickness, Fatigue or exhaustion.
- #55 Cyclic vomiting syndrome – Wikipediahttps://en.wikipedia.org/wiki/Cyclic_vomiting_syndrome
Episodes may happen every few days, every few weeks or every few months, for some happening at common uniform times, typically mornings. For other affected people, there is not a pattern in time that can be recognized. Some with the condition have a warning of an episodic attack; they may experience a prodrome, some documented prodromal symptoms include: unusually intense nausea and pallor, excess salivation, sweating, flushing, rapid/irregular heartbeat, diarrhea, anxiety/panic, food aversion, restlessness/insomnia, irritability, depersonalization, fatigue/listlessness, intense feelings of being hot or chilled, intense thirst, shivering/shaking, retching, tachypnea, abdominal pain/cramping, limb paresthesias, hyperesthesia, photophobia, phonophobia, headache, and dyspnea, heightened sensitivity, especially to light, though sensitivity to smell, sound, pressure, and temperature, as well as oncoming muscle pain and fatigue, are also reported by some patients. Many experience a full panic attack when nausea begins and continue to panic once the vomiting has begun.
- #56 Cyclic Vomiting Syndrome in 41 adults: the illness, the patients, and problems of management | BMC Medicine | Full Texthttps://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-3-20/tables/1
Nausea […] Sweating […] Epigastric pain or „pressure” […] Fatigue or weakness […] Feeling hot and/or chilly […] Cramping urge to defecate […] Abdominal pain […] Shivering or shakiness […] Insomnia or restless, interrupted sleep […] Aversion for food […] Pounding or irregular heartbeat […] Irritability […] „Panic feelings” […] Intense thirst […] Feelings of depersonalization […] Headache […] Increased salivation […] Dyspnea […] A sensation of abdominal bloating […] Inability to burp […] Excessive burping […] Inability to effect the desired passage of stool or flatus […] Loose stooling […] Epigastric burning […] Paresthesias […] Light headedness
- #57 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age. […] The episodes of nausea, vomiting, and lethargy last anywhere from an hour to 10 days. An affected person may vomit several times per hour, potentially leading to a dangerous loss of fluids (dehydration). Additional symptoms can include unusually pale skin (pallor), abdominal pain, diarrhea, headache, fever, and an increased sensitivity to light (photophobia) or to sound (phonophobia). In most affected people, the signs and symptoms of each attack are quite similar. These attacks can be debilitating, making it difficult for an affected person to go to work or school. […] Episodes of nausea, vomiting, and lethargy can occur regularly or apparently at random, or can be triggered by a variety of factors. The most common triggers are emotional excitement and infections. Other triggers can include periods without eating (fasting), temperature extremes, lack of sleep, overexertion, allergies, ingesting certain foods or alcohol, and menstruation.
- #58 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
The most common precipitating event is infection (41%), particularly chronic sinusitis. […] Approximately 68% of families are able to identify events that appear to precipitate a patient’s episode. […] The terms cyclic vomiting syndrome and abdominal migraine have often been used interchangeably because of the considerable overlap in clinical criteria. […] Because 80% of children with CVS have abdominal pain, and 50% of those with abdominal pain vomit, many children can be diagnosed with either CVS or abdominal migraine. […] The following 3 additional criteria help strengthen the diagnosis of CVS: Negative screening test results to exclude common GI, hepatobiliary, renal, metabolic, and endocrine disorders; Subsequent development of migraine headaches; A positive response to antimigraine medications. […] Clinical features of CVS are summarized in Table 2 below.
- #59 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age. […] The episodes of nausea, vomiting, and lethargy last anywhere from an hour to 10 days. An affected person may vomit several times per hour, potentially leading to a dangerous loss of fluids (dehydration). Additional symptoms can include unusually pale skin (pallor), abdominal pain, diarrhea, headache, fever, and an increased sensitivity to light (photophobia) or to sound (phonophobia). In most affected people, the signs and symptoms of each attack are quite similar. These attacks can be debilitating, making it difficult for an affected person to go to work or school. […] Episodes of nausea, vomiting, and lethargy can occur regularly or apparently at random, or can be triggered by a variety of factors. The most common triggers are emotional excitement and infections. Other triggers can include periods without eating (fasting), temperature extremes, lack of sleep, overexertion, allergies, ingesting certain foods or alcohol, and menstruation.
- #60 Cyclic Vomiting Syndrome: Diagnostic Criteria and Insights into Long Term Treatment Outcomes – Practical Gastrohttps://practicalgastro.com/2015/01/05/cyclic-vomiting-syndrome-diagnostic-criteria-and-insights-into-long-term-treatment-outcomes/
CVS results in a significant morbidity for patients with loss of time at work or school, a significant disruption in professional and personal life as well as an economic burden. […] CVS in adults can range from mild disease with infrequent episodes to severe debilitating disease requiring multiple emergency department (ED) visits and frequent hospitalizations. […] The majority of CVS attacks occur without any warning although in retrospect patients report that up to 60-80% of CVS attacks can be associated with a trigger mechanism such as infection, psychological stress, emotional stress, physical stress, lack of sleep, diet, motion sickness and onset of menses. […] The anxiety present in CVS patients, including panic disorder, has been reported to trigger attacks in 66% of cases. […] Long term treatment of CVS is based on trying to identify the etiologic subgroups particularly the role of psychological stress while prescribing prophylactic drug and abortive therapy and supportive measures to ameliorate acute vomiting episodes.
- #61 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age. […] The episodes of nausea, vomiting, and lethargy last anywhere from an hour to 10 days. An affected person may vomit several times per hour, potentially leading to a dangerous loss of fluids (dehydration). Additional symptoms can include unusually pale skin (pallor), abdominal pain, diarrhea, headache, fever, and an increased sensitivity to light (photophobia) or to sound (phonophobia). In most affected people, the signs and symptoms of each attack are quite similar. These attacks can be debilitating, making it difficult for an affected person to go to work or school. […] Episodes of nausea, vomiting, and lethargy can occur regularly or apparently at random, or can be triggered by a variety of factors. The most common triggers are emotional excitement and infections. Other triggers can include periods without eating (fasting), temperature extremes, lack of sleep, overexertion, allergies, ingesting certain foods or alcohol, and menstruation.
- #62 Understanding Cyclic Vomiting Syndrome (CVS) | Saint Luke’s Health Systemhttps://www.saintlukeskc.org/health-library/understanding-cyclic-vomiting-syndrome-cvs
Cyclic vomiting syndrome (CVS) is an uncommon health problem in adults. It occurs when you have sudden, recurring episodes or attacks of vomiting. The main symptom of CVS is sudden, recurring episodes of vomiting. They may occur several times a month or several times a year. The episodes follow a similar pattern every time you have them. They tend to start at the same time and last about the same amount of time (hours to days). The pattern is unique to you. Between episodes, you won’t have any nausea or vomiting. […] You may have these other symptoms during an attack: Stomach pain, Heaving, Fever, Loss of appetite, Dizziness, Sensitivity to light, Sluggishness, Diarrhea. Some people with CVS find that symptoms start after a certain trigger. Triggers may include stress, a lack of sleep, substance use, an infection, and certain foods like chocolate or cheese. In women, the syndrome may happen at the same time as their menstrual period.
- #63 Cyclic Vomiting Syndrome – Center For Digestive Healthhttps://troygastro.com/conditions/cyclic-vomiting-syndrome/
Cyclic vomiting syndrome cannot be cured, but children tend to grow out of vomiting episodes by the time they reach adulthood. Treatment for cyclic vomiting syndrome focuses on alleviating symptoms of nausea and vomiting. […] While vomiting episodes tend to have no explanation, certain risk factors may trigger them. These include allergies, colds, triggering foods, overeating, fasting, motion sickness, menstruation, physical exhaustion, and hot temperatures. In children, stress and excitement can trigger an episode, whereas anxiety can lead to vomiting in adults. […] A doctor may recommend nitroglycerin applied externally to relax the anal sphincter and There are treatments that can manage the symptoms of cyclic vomiting syndrome. The typical course of treatment is some sort of medication, such as anti-nausea drugs, antacids, or medication to treat migraines. In severe cases, a person may require intravenous fluids to treat dehydration from vomiting. […] While there is no established cure, most children do grow out of cyclic vomiting syndrome. This is why treatment focuses on alleviating symptoms.
- #64 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic of CVS. […] Although periods of complete normality typically occur between episodes, many adult patients lose the cyclic pattern of symptoms over time, and 63% of them develop inter episodic symptoms (often nausea) between episodes; this pattern is termed coalescence. […] The vomiting in CVS is typically much more severe and intermittent than that observed in gastroesophageal reflux. […] The stereotypical on-off pattern often begins with a prodrome of nausea and pallor. Vomiting peaks in the first hour and then begins to decline over the ensuing 4-8 hours, lasting a mean of 24 hours (median, 43 hours).
- #65 Cyclic Vomiting Syndrome | Children’s Hospital of Philadelphiahttps://www.chop.edu/conditions-diseases/cyclic-vomiting
Cyclic vomiting syndrome (CVS) is a condition that involves recurrent episodes of vomiting with three main features: sudden onset, stereotypical (similar episodes), and periods of wellness between episodes. […] CVS symptoms include vomiting episodes that recur in a cyclical pattern (for example every two weeks or once a month). The vomiting episodes start suddenly, typically beginning with nausea, and progress to vomiting later. The episodes can sometimes wake the affected person from sleep. […] The episodes are stereotypical which means that each new episode resembles previous episodes. Other symptoms can include stomach pain, diarrhea and headache. The vomiting attacks can become so severe that patients become dehydrated and require medical attention. […] In between episodes, patients generally feel completely well. Once an episode resolves, affected children often feel normal within hours. […] Once patients are properly diagnosed and treated, most improve. Additionally, many children outgrow the diagnosis before adulthood.
- #66 Cyclic Vomiting Syndrome: Symptoms, Causes & Triggers, Treatmenthttps://my.clevelandclinic.org/health/diseases/14894-cyclic-vomiting-syndrome
Cyclic vomiting syndrome is when you experience cycles of severe nausea, vomiting and exhaustion that can last from a few hours up to a few days. Episodes can last from a few hours to several days. They can be so severe that you need to stay in bed. You may need to go to the emergency room (ER) or hospital to get IV fluids to prevent dehydration. […] CVS may last for months, years or decades. However, symptoms dont occur every day. Episodes generally occur several times a year but can happen up to once or twice a month. […] The symptoms, time of day, frequency, severity and length of each episode are usually the same for any one person. But these factors can vary from person to person. […] Cyclic vomiting syndrome (CVS) involves sudden, repeated episodes of severe nausea and vomiting.
- #67 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic of CVS. […] Although periods of complete normality typically occur between episodes, many adult patients lose the cyclic pattern of symptoms over time, and 63% of them develop inter episodic symptoms (often nausea) between episodes; this pattern is termed coalescence. […] The vomiting in CVS is typically much more severe and intermittent than that observed in gastroesophageal reflux. […] The stereotypical on-off pattern often begins with a prodrome of nausea and pallor. Vomiting peaks in the first hour and then begins to decline over the ensuing 4-8 hours, lasting a mean of 24 hours (median, 43 hours).
- #68 Cyclic Vomiting Syndrome â CVS | Ohio State Medical Centerhttps://wexnermedical.osu.edu/digestive-diseases/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is a chronic disease marked by severe and recurrent episodes of nausea and vomiting that occur every 10 minutes for several hours. […] During a CVS episode, vomiting can be severe and may occur as often as every 10 minutes for several hours. […] CVS is marked by severe and recurrent episodes of vomiting. During an attack, vomiting may occur every five to 10 minutes for several hours. In general, most episodes last three to seven days. Episodes often start in the middle of the night or early morning hours. […] Other symptoms during an episode can include: Severe nausea, Severe stomach pain, Tiredness, Sensitivity to light, Headaches.
- #69 Cyclic Vomiting Syndrome in Childrenhttps://www.uspharmacist.com/article/cyclic-vomiting-syndrome-in-children
The vomiting episodes usually last for 1 to 3 days. […] The recovery phase begins with the disappearance of nausea and vomiting and lasts until the child resumes normal appetite and activity. Some children may be able to return to eating within a couple of hours, but many will take a few days to return to a regular diet and get their energy back. […] Complications of CVS include severe dehydration, electrolyte imbalances, hematemesis, Mallory-Weiss tear of the esophagus, aspiration, and hypovolemic shock. […] Abdominal pain, diarrhea, fever, dizziness, and sensitivity to light often accompany the vomiting during acute episodes. […] Immediate treatment of vomiting attacks is crucial, since the physical stress of the episode predisposes the patient to more vomiting and perpetuates the cycle.
- #70 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age. […] The episodes of nausea, vomiting, and lethargy last anywhere from an hour to 10 days. An affected person may vomit several times per hour, potentially leading to a dangerous loss of fluids (dehydration). Additional symptoms can include unusually pale skin (pallor), abdominal pain, diarrhea, headache, fever, and an increased sensitivity to light (photophobia) or to sound (phonophobia). In most affected people, the signs and symptoms of each attack are quite similar. These attacks can be debilitating, making it difficult for an affected person to go to work or school. […] Episodes of nausea, vomiting, and lethargy can occur regularly or apparently at random, or can be triggered by a variety of factors. The most common triggers are emotional excitement and infections. Other triggers can include periods without eating (fasting), temperature extremes, lack of sleep, overexertion, allergies, ingesting certain foods or alcohol, and menstruation.
- #71 Cyclic Vomiting Syndrome | MNGIhttps://www.mngi.com/conditions/cyclic-vomiting-syndrome
Cyclic vomiting syndrome, people have episodes or cycles of severe nausea and vomiting that may last for hours or days. Symptoms usually start between the ages of 3 and 7, and may be linked to migraine headaches. The symptoms of cyclic vomiting syndrome are severe vomiting, nausea, and gagging. Episodes usually begin late at night or early in the morning. In children, attacks usually last between 24 and 48 hours. Adults can have symptoms for almost one week. Other symptoms of cyclic vomiting syndrome may be pale skin, feeling very tired and weak, headaches, fever, diarrhea, and abdominal pain. […] About one-half of children have attacks every two to four weeks. Adults may have episodes less often. Possible complications are dehydration, injury to the esophagus (tube that connects the mouth to the stomach) and rotting of teeth.
- #72 Cyclic vomiting syndrome – Wikipediahttps://en.wikipedia.org/wiki/Cyclic_vomiting_syndrome
Episodes may happen every few days, every few weeks or every few months, for some happening at common uniform times, typically mornings. For other affected people, there is not a pattern in time that can be recognized. Some with the condition have a warning of an episodic attack; they may experience a prodrome, some documented prodromal symptoms include: unusually intense nausea and pallor, excess salivation, sweating, flushing, rapid/irregular heartbeat, diarrhea, anxiety/panic, food aversion, restlessness/insomnia, irritability, depersonalization, fatigue/listlessness, intense feelings of being hot or chilled, intense thirst, shivering/shaking, retching, tachypnea, abdominal pain/cramping, limb paresthesias, hyperesthesia, photophobia, phonophobia, headache, and dyspnea, heightened sensitivity, especially to light, though sensitivity to smell, sound, pressure, and temperature, as well as oncoming muscle pain and fatigue, are also reported by some patients. Many experience a full panic attack when nausea begins and continue to panic once the vomiting has begun.
- #73 Cyclic Vomiting Syndrome | MNGIhttps://www.mngi.com/conditions/cyclic-vomiting-syndrome
Cyclic vomiting syndrome, people have episodes or cycles of severe nausea and vomiting that may last for hours or days. Symptoms usually start between the ages of 3 and 7, and may be linked to migraine headaches. The symptoms of cyclic vomiting syndrome are severe vomiting, nausea, and gagging. Episodes usually begin late at night or early in the morning. In children, attacks usually last between 24 and 48 hours. Adults can have symptoms for almost one week. Other symptoms of cyclic vomiting syndrome may be pale skin, feeling very tired and weak, headaches, fever, diarrhea, and abdominal pain. […] About one-half of children have attacks every two to four weeks. Adults may have episodes less often. Possible complications are dehydration, injury to the esophagus (tube that connects the mouth to the stomach) and rotting of teeth.
- #74 Cyclic vomiting syndrome: From pathophysiology to treatment | Revista de GastroenterologÃa de Méxicohttps://www.revistagastroenterologiamexico.org/en-cyclic-vomiting-syndrome-from-pathophysiology-articulo-S2255534X24000616
Once the vomiting has ceased, patients slowly tolerate oral intake before returning to their normal routine. […] The frequency of CVS episodes varies from every two-to-three weeks to three times a year. Episode duration can vary from hours to several days. […] The clinical history is essential in the diagnosis of CVS, which is characterized by episodes of incoercible vomiting, alternating with periods of few or no symptoms. […] The definitive diagnosis is currently made in patients that meet the Rome criteria and in whom other causes of emesis have been ruled out through a detailed clinical history and the previously mentioned tests. […] It is necessary to avoid the triggers identified by the patient (insomnia, fasting, stress). […] Given that chronic cannabis consumption is associated with the lack of treatment response, its use should be suspended.
- #75 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
If the condition is not treated, episodes usually occur four to 12 times per year. Between attacks, vomiting is absent, and nausea is either absent or much reduced. However, many affected people experience other symptoms during and between episodes, including pain, lethargy, digestive disorders such as gastroesophageal reflux and irritable bowel syndrome, and fainting spells (syncope). People with cyclic vomiting syndrome are also more likely than people without the disorder to experience depression, anxiety, and panic disorder. It is unclear whether these health conditions are directly related to nausea and vomiting. […] Cyclic vomiting syndrome is often considered to be a variant of migraines, which are severe headaches often associated with pain, nausea, vomiting, and extreme sensitivity to light and sound. Cyclic vomiting syndrome is likely the same as or closely related to a condition called abdominal migraine, which is characterized by attacks of stomach pain and cramping. Attacks of nausea, vomiting, or abdominal pain in childhood may be replaced by migraine headaches as an affected person gets older. Many people with cyclic vomiting syndrome or abdominal migraine have a family history of migraines.
- #76 Cyclic Vomiting Syndrome in 41 adults: the illness, the patients, and problems of management | BMC Medicine | Full Texthttps://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-3-20
The emetic phase was characterized by persistence of many prodromal symptoms plus severe, persistent nausea and vomiting. […] The deterioration of CVS took the form of near- or complete coalescence of episodes. A near-coalescence occurs when episodes recur with increasing frequency. […] The typical length of the recovery phase was reported by 22 patients and ranged from minutes to as much as ten days.
- #77 FAQ: Cyclic Vomiting Syndrome | Ohio State Health & Discoveryhttps://health.osu.edu/health/general-health/faq-cyclic-vomiting-syndrome
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) characterized by recurrent episodes of severe nausea, vomiting and often abdominal pain. It can be accompanied by other symptoms, such as excessive sweating, hot and cold flashes, diarrhea and sometimes headaches. […] CVS begins abruptly and usually occurs out of the blue, lasting hours to several days or even a week. In between episodes, individuals have periods of normal health, without any symptoms or can have some nausea and occasional abdominal discomfort at baseline. These symptom-free intervals can last for weeks to months. […] However, if left untreated, people with CVS may experience longer and more frequent episodes, potentially leading to a condition called coalescent CVS, in which the typical normal or inter-episodic phase is lost.
- #78 Cyclic Vomiting Syndrome â CVS | Ohio State Medical Centerhttps://wexnermedical.osu.edu/digestive-diseases/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is a chronic disease marked by severe and recurrent episodes of nausea and vomiting that occur every 10 minutes for several hours. […] During a CVS episode, vomiting can be severe and may occur as often as every 10 minutes for several hours. […] CVS is marked by severe and recurrent episodes of vomiting. During an attack, vomiting may occur every five to 10 minutes for several hours. In general, most episodes last three to seven days. Episodes often start in the middle of the night or early morning hours. […] Other symptoms during an episode can include: Severe nausea, Severe stomach pain, Tiredness, Sensitivity to light, Headaches.
- #79 Cyclic Vomiting Syndrome | Children’s Hospital of Philadelphiahttps://www.chop.edu/conditions-diseases/cyclic-vomiting
Cyclic vomiting syndrome (CVS) is a condition that involves recurrent episodes of vomiting with three main features: sudden onset, stereotypical (similar episodes), and periods of wellness between episodes. […] CVS symptoms include vomiting episodes that recur in a cyclical pattern (for example every two weeks or once a month). The vomiting episodes start suddenly, typically beginning with nausea, and progress to vomiting later. The episodes can sometimes wake the affected person from sleep. […] The episodes are stereotypical which means that each new episode resembles previous episodes. Other symptoms can include stomach pain, diarrhea and headache. The vomiting attacks can become so severe that patients become dehydrated and require medical attention. […] In between episodes, patients generally feel completely well. Once an episode resolves, affected children often feel normal within hours. […] Once patients are properly diagnosed and treated, most improve. Additionally, many children outgrow the diagnosis before adulthood.
- #80 Cyclic vomiting syndrome – Wikipediahttps://en.wikipedia.org/wiki/Cyclic_vomiting_syndrome
Episodes may happen every few days, every few weeks or every few months, for some happening at common uniform times, typically mornings. For other affected people, there is not a pattern in time that can be recognized. Some with the condition have a warning of an episodic attack; they may experience a prodrome, some documented prodromal symptoms include: unusually intense nausea and pallor, excess salivation, sweating, flushing, rapid/irregular heartbeat, diarrhea, anxiety/panic, food aversion, restlessness/insomnia, irritability, depersonalization, fatigue/listlessness, intense feelings of being hot or chilled, intense thirst, shivering/shaking, retching, tachypnea, abdominal pain/cramping, limb paresthesias, hyperesthesia, photophobia, phonophobia, headache, and dyspnea, heightened sensitivity, especially to light, though sensitivity to smell, sound, pressure, and temperature, as well as oncoming muscle pain and fatigue, are also reported by some patients. Many experience a full panic attack when nausea begins and continue to panic once the vomiting has begun.
- #81 Cyclic vomiting syndrome – Wikipediahttps://en.wikipedia.org/wiki/Cyclic_vomiting_syndrome
Episodes may happen every few days, every few weeks or every few months, for some happening at common uniform times, typically mornings. For other affected people, there is not a pattern in time that can be recognized. Some with the condition have a warning of an episodic attack; they may experience a prodrome, some documented prodromal symptoms include: unusually intense nausea and pallor, excess salivation, sweating, flushing, rapid/irregular heartbeat, diarrhea, anxiety/panic, food aversion, restlessness/insomnia, irritability, depersonalization, fatigue/listlessness, intense feelings of being hot or chilled, intense thirst, shivering/shaking, retching, tachypnea, abdominal pain/cramping, limb paresthesias, hyperesthesia, photophobia, phonophobia, headache, and dyspnea, heightened sensitivity, especially to light, though sensitivity to smell, sound, pressure, and temperature, as well as oncoming muscle pain and fatigue, are also reported by some patients. Many experience a full panic attack when nausea begins and continue to panic once the vomiting has begun.
- #82 Cyclic vomiting syndrome – Hancock Healthhttps://www.hancockhealth.org/mayo-health-library/cyclic-vomiting-syndrome/
Continued vomiting may cause severe dehydration that can be life-threatening. Call your doctor if you or your child is showing symptoms of dehydration, such as: Excess thirst or dry mouth, Less urination, Dry skin, Sunken eyes or cheeks, No tears when crying, Exhaustion and listlessness. […] Cyclic vomiting syndrome can cause these complications: Dehydration. Excessive vomiting causes the body to lose water quickly. Severe cases of dehydration may need to be treated in the hospital. Injury to the food tube. The stomach acid that comes up with the vomit can damage the tube that connects the mouth and stomach (esophagus). Sometimes the esophagus becomes so irritated it bleeds. Tooth decay. The acid in vomit can corrode tooth enamel. […] Many people know what triggers their cyclic vomiting episodes. Avoiding those triggers can reduce the frequency of episodes.
- #83 Cyclic vomiting syndrome – Hancock Healthhttps://www.hancockhealth.org/mayo-health-library/cyclic-vomiting-syndrome/
Continued vomiting may cause severe dehydration that can be life-threatening. Call your doctor if you or your child is showing symptoms of dehydration, such as: Excess thirst or dry mouth, Less urination, Dry skin, Sunken eyes or cheeks, No tears when crying, Exhaustion and listlessness. […] Cyclic vomiting syndrome can cause these complications: Dehydration. Excessive vomiting causes the body to lose water quickly. Severe cases of dehydration may need to be treated in the hospital. Injury to the food tube. The stomach acid that comes up with the vomit can damage the tube that connects the mouth and stomach (esophagus). Sometimes the esophagus becomes so irritated it bleeds. Tooth decay. The acid in vomit can corrode tooth enamel. […] Many people know what triggers their cyclic vomiting episodes. Avoiding those triggers can reduce the frequency of episodes.
- #84 Cyclic Vomiting Syndrome – Center For Digestive Healthhttps://troygastro.com/conditions/cyclic-vomiting-syndrome/
Cyclic vomiting syndrome is a condition that involves unexplained episodes of severe vomiting. Vomiting episodes may last for several hours or even several days, with symptom-free periods between episodes. […] Vomiting episodes usually start with extreme nausea and sweating. Additional symptoms of an episode of cyclic vomiting syndrome include: Pain in the abdomen, Headache, Dizziness, Light sensitivity, Diarrhea, Gagging. […] Cyclic vomiting syndrome is diagnosed when a person experiences three or more episodes of recurrent vomiting, with periods of normal health between episodes. […] Cyclic vomiting syndrome can cause complications, as repeated vomiting can lead to dehydration. In some cases, dehydration can be severe and life-threatening. Signs of dehydration with cyclic vomiting syndrome are as follows: Dry mouth, Extreme thirst, Dryness of the skin, Lack of energy, Crying without tears, Sunken in eyes or cheeks.
- #85 Cyclic vomiting syndrome – Hancock Healthhttps://www.hancockhealth.org/mayo-health-library/cyclic-vomiting-syndrome/
Continued vomiting may cause severe dehydration that can be life-threatening. Call your doctor if you or your child is showing symptoms of dehydration, such as: Excess thirst or dry mouth, Less urination, Dry skin, Sunken eyes or cheeks, No tears when crying, Exhaustion and listlessness. […] Cyclic vomiting syndrome can cause these complications: Dehydration. Excessive vomiting causes the body to lose water quickly. Severe cases of dehydration may need to be treated in the hospital. Injury to the food tube. The stomach acid that comes up with the vomit can damage the tube that connects the mouth and stomach (esophagus). Sometimes the esophagus becomes so irritated it bleeds. Tooth decay. The acid in vomit can corrode tooth enamel. […] Many people know what triggers their cyclic vomiting episodes. Avoiding those triggers can reduce the frequency of episodes.
- #86 Cyclic vomiting syndrome – Hancock Healthhttps://www.hancockhealth.org/mayo-health-library/cyclic-vomiting-syndrome/
Continued vomiting may cause severe dehydration that can be life-threatening. Call your doctor if you or your child is showing symptoms of dehydration, such as: Excess thirst or dry mouth, Less urination, Dry skin, Sunken eyes or cheeks, No tears when crying, Exhaustion and listlessness. […] Cyclic vomiting syndrome can cause these complications: Dehydration. Excessive vomiting causes the body to lose water quickly. Severe cases of dehydration may need to be treated in the hospital. Injury to the food tube. The stomach acid that comes up with the vomit can damage the tube that connects the mouth and stomach (esophagus). Sometimes the esophagus becomes so irritated it bleeds. Tooth decay. The acid in vomit can corrode tooth enamel. […] Many people know what triggers their cyclic vomiting episodes. Avoiding those triggers can reduce the frequency of episodes.
- #87 Cyclic Vomiting â Digestive Topicshttps://gikids.org/digestive-topics/cyclic-vomiting/
Other symptoms can include nausea, severe stomach pain, diarrhea, headache, lack of appetite, light sensitivity, and low fever. Patients can become disoriented, irritable, and turn pale and clammy during an attack. Some patients vomit until they dry heave and become dehydrated. […] Patients with CVS have periods of intervening wellness in between attacks, they feel completely normal without any symptoms. Usually this occurs within a few hours after an attack, or when they awake from sleep after an episode. Patients can experience a period of wellness for weeks to months (1-3 months on average). Some patients have more frequent episodes that occur every 1-3 weeks, while others may have rare episodes that occur every 6-12 months. […] Complications of cyclic vomiting can include dehydration, inflammation of the esophagus (esophagitis), small tears in the lining of the esophagus (Mallory-Weiss tear), or tooth enamel decay due to recurrent vomiting. […] Fortunately, most patients improve once properly diagnosed and treated.
- #88 Cyclic vomiting syndrome – Hancock Healthhttps://www.hancockhealth.org/mayo-health-library/cyclic-vomiting-syndrome/
Continued vomiting may cause severe dehydration that can be life-threatening. Call your doctor if you or your child is showing symptoms of dehydration, such as: Excess thirst or dry mouth, Less urination, Dry skin, Sunken eyes or cheeks, No tears when crying, Exhaustion and listlessness. […] Cyclic vomiting syndrome can cause these complications: Dehydration. Excessive vomiting causes the body to lose water quickly. Severe cases of dehydration may need to be treated in the hospital. Injury to the food tube. The stomach acid that comes up with the vomit can damage the tube that connects the mouth and stomach (esophagus). Sometimes the esophagus becomes so irritated it bleeds. Tooth decay. The acid in vomit can corrode tooth enamel. […] Many people know what triggers their cyclic vomiting episodes. Avoiding those triggers can reduce the frequency of episodes.
- #89 FAQ: Cyclic Vomiting Syndrome | Ohio State Health & Discoveryhttps://health.osu.edu/health/general-health/faq-cyclic-vomiting-syndrome
The severity and duration vary from person to person, but episodes for each individual are typically consistent. […] CVS is a chronic disorder that can be managed but doesnt go away. However, some seniors with CVS have outgrown vomiting and instead develop episodes of migraine headaches. A large proportion of children with CVS outgrow symptoms but develop migraine headaches or chronic abdominal pain. […] Medication and other treatments, like behavioral therapy and meditation, can help manage the symptoms of CVS. […] Cyclic vomiting syndrome is not a life-threatening condition. However, its important to note that severe episodes of vomiting can lead to complications like severe dehydration and acute kidney injury. Some patients can develop suicidal ideation, particularly if theyre unable to find a doctor who cares for patients with CVS.
- #90 Cyclic Vomiting Syndrome: Practice Essentials, Pathophysiology and Etiology, Epidemiologyhttps://emedicine.medscape.com/article/933135-overview
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic. […] Most published series indicate that CVS lasts an average of 2.5-5.5 years, resolving in late childhood or early adolescence. A few patients continue to be symptomatic through adulthood. […] A survey by Abu-Arafeh et al found the mean ages of children with CVS, abdominal migraines, and migraine headaches to be 5.3 years, 10.3 years, and 11.5 years, respectively. This finding supports the developmental progression from vomiting to abdominal pain to headache. […] Although patients are well about 90% of the time, CVS can be medically and socially disabling. More than 50% of patients require intravenous (IV) fluids, compared with less than 1% of patients with rotavirus gastroenteritis. The average annual cost of testing, treatment, and absenteeism totals $17,000. Children miss an average of 24 school days per year and often need home tutoring or, occasionally, home schooling. Additionally, because of its frequency during times of excitement, CVS has ruined many birthdays, holidays, and vacations. […] In adults, substantial morbidity is associated with CVS, perhaps because of lack of awareness and resultant delays in diagnosis. In a study of 41 CVS patients, Fleisher found that 32% were completely disabled at the time of diagnosis.
- #91 Cyclic Vomiting Syndrome: Causes, Treatment, and Morehttps://www.healthline.com/health/cyclic-vomiting-syndrome
Some people might develop nausea and sweating just before an episode of vomiting. […] CVS can make it difficult to attend work or school. However, many people are able to function as expected in between episodes. […] CVS involves recurring episodes of vomiting and nausea. These symptoms can be severe and cause serious complications, like dehydration.
- #92 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Patients are usually asymptomatic between episodes but ~ 30% can have interepisodic nausea and dyspepsia. In some patients, episodes become progressively longer and the interepisodic phase is considerably shortened and patients have a âcoalescence of symptoms.â […] The severity and unpredictable nature of symptoms makes it difficult for some patients to attend school or work; one study found that 32% of patients with CVS were completely disabled. […] CVS is associated with various comorbidities such as migraine, anxiety, depression and dysautonomia, which can further impair quality of life. Approximately 70% of CVS patients report a personal or family history of migraine. Anxiety and depression affects nearly half of patients with CVS.
- #93 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Patients are usually asymptomatic between episodes but ~ 30% can have interepisodic nausea and dyspepsia. In some patients, episodes become progressively longer and the interepisodic phase is considerably shortened and patients have a âcoalescence of symptoms.â […] The severity and unpredictable nature of symptoms makes it difficult for some patients to attend school or work; one study found that 32% of patients with CVS were completely disabled. […] CVS is associated with various comorbidities such as migraine, anxiety, depression and dysautonomia, which can further impair quality of life. Approximately 70% of CVS patients report a personal or family history of migraine. Anxiety and depression affects nearly half of patients with CVS.
- #94 Cyclic Vomiting Syndrome: Practice Essentials, Pathophysiology and Etiology, Epidemiologyhttps://emedicine.medscape.com/article/933135-overview
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic. […] Most published series indicate that CVS lasts an average of 2.5-5.5 years, resolving in late childhood or early adolescence. A few patients continue to be symptomatic through adulthood. […] A survey by Abu-Arafeh et al found the mean ages of children with CVS, abdominal migraines, and migraine headaches to be 5.3 years, 10.3 years, and 11.5 years, respectively. This finding supports the developmental progression from vomiting to abdominal pain to headache. […] Although patients are well about 90% of the time, CVS can be medically and socially disabling. More than 50% of patients require intravenous (IV) fluids, compared with less than 1% of patients with rotavirus gastroenteritis. The average annual cost of testing, treatment, and absenteeism totals $17,000. Children miss an average of 24 school days per year and often need home tutoring or, occasionally, home schooling. Additionally, because of its frequency during times of excitement, CVS has ruined many birthdays, holidays, and vacations. […] In adults, substantial morbidity is associated with CVS, perhaps because of lack of awareness and resultant delays in diagnosis. In a study of 41 CVS patients, Fleisher found that 32% were completely disabled at the time of diagnosis.
- #95 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Patients are usually asymptomatic between episodes but ~ 30% can have interepisodic nausea and dyspepsia. In some patients, episodes become progressively longer and the interepisodic phase is considerably shortened and patients have a âcoalescence of symptoms.â […] The severity and unpredictable nature of symptoms makes it difficult for some patients to attend school or work; one study found that 32% of patients with CVS were completely disabled. […] CVS is associated with various comorbidities such as migraine, anxiety, depression and dysautonomia, which can further impair quality of life. Approximately 70% of CVS patients report a personal or family history of migraine. Anxiety and depression affects nearly half of patients with CVS.
- #96 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Patients are usually asymptomatic between episodes but ~ 30% can have interepisodic nausea and dyspepsia. In some patients, episodes become progressively longer and the interepisodic phase is considerably shortened and patients have a âcoalescence of symptoms.â […] The severity and unpredictable nature of symptoms makes it difficult for some patients to attend school or work; one study found that 32% of patients with CVS were completely disabled. […] CVS is associated with various comorbidities such as migraine, anxiety, depression and dysautonomia, which can further impair quality of life. Approximately 70% of CVS patients report a personal or family history of migraine. Anxiety and depression affects nearly half of patients with CVS.
- #97 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Patients are usually asymptomatic between episodes but ~ 30% can have interepisodic nausea and dyspepsia. In some patients, episodes become progressively longer and the interepisodic phase is considerably shortened and patients have a âcoalescence of symptoms.â […] The severity and unpredictable nature of symptoms makes it difficult for some patients to attend school or work; one study found that 32% of patients with CVS were completely disabled. […] CVS is associated with various comorbidities such as migraine, anxiety, depression and dysautonomia, which can further impair quality of life. Approximately 70% of CVS patients report a personal or family history of migraine. Anxiety and depression affects nearly half of patients with CVS.
- #98 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Patients are usually asymptomatic between episodes but ~ 30% can have interepisodic nausea and dyspepsia. In some patients, episodes become progressively longer and the interepisodic phase is considerably shortened and patients have a âcoalescence of symptoms.â […] The severity and unpredictable nature of symptoms makes it difficult for some patients to attend school or work; one study found that 32% of patients with CVS were completely disabled. […] CVS is associated with various comorbidities such as migraine, anxiety, depression and dysautonomia, which can further impair quality of life. Approximately 70% of CVS patients report a personal or family history of migraine. Anxiety and depression affects nearly half of patients with CVS.
- #99 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
If the condition is not treated, episodes usually occur four to 12 times per year. Between attacks, vomiting is absent, and nausea is either absent or much reduced. However, many affected people experience other symptoms during and between episodes, including pain, lethargy, digestive disorders such as gastroesophageal reflux and irritable bowel syndrome, and fainting spells (syncope). People with cyclic vomiting syndrome are also more likely than people without the disorder to experience depression, anxiety, and panic disorder. It is unclear whether these health conditions are directly related to nausea and vomiting. […] Cyclic vomiting syndrome is often considered to be a variant of migraines, which are severe headaches often associated with pain, nausea, vomiting, and extreme sensitivity to light and sound. Cyclic vomiting syndrome is likely the same as or closely related to a condition called abdominal migraine, which is characterized by attacks of stomach pain and cramping. Attacks of nausea, vomiting, or abdominal pain in childhood may be replaced by migraine headaches as an affected person gets older. Many people with cyclic vomiting syndrome or abdominal migraine have a family history of migraines.
- #100 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
If the condition is not treated, episodes usually occur four to 12 times per year. Between attacks, vomiting is absent, and nausea is either absent or much reduced. However, many affected people experience other symptoms during and between episodes, including pain, lethargy, digestive disorders such as gastroesophageal reflux and irritable bowel syndrome, and fainting spells (syncope). People with cyclic vomiting syndrome are also more likely than people without the disorder to experience depression, anxiety, and panic disorder. It is unclear whether these health conditions are directly related to nausea and vomiting. […] Cyclic vomiting syndrome is often considered to be a variant of migraines, which are severe headaches often associated with pain, nausea, vomiting, and extreme sensitivity to light and sound. Cyclic vomiting syndrome is likely the same as or closely related to a condition called abdominal migraine, which is characterized by attacks of stomach pain and cramping. Attacks of nausea, vomiting, or abdominal pain in childhood may be replaced by migraine headaches as an affected person gets older. Many people with cyclic vomiting syndrome or abdominal migraine have a family history of migraines.
- #101 Cyclic Vomiting Syndrome Causes, Symptoms, Diet, Treatmenthttps://www.medicinenet.com/cyclic_vomiting_syndrome_cvs/article.htm
The prognosis for CVS varies. Patients with complications and weak responses to treatment have a fair prognosis while others may respond well and have a good prognosis. In general, CVS lasts about two and a half to five and a half years, resolving late childhood or early adolescence. Some patients go on to develop migraine headaches, and a few patients have CVS extend into adulthood. Patients with a diagnosis of cyclic vomiting syndrome plus have a prognosis usually ranging from fair to poor.
- #102 Cyclic Vomiting Syndrome: Symptoms, Causes & Triggers, Treatmenthttps://my.clevelandclinic.org/health/diseases/14894-cyclic-vomiting-syndrome
Cyclic vomiting syndrome is when you experience cycles of severe nausea, vomiting and exhaustion that can last from a few hours up to a few days. Episodes can last from a few hours to several days. They can be so severe that you need to stay in bed. You may need to go to the emergency room (ER) or hospital to get IV fluids to prevent dehydration. […] CVS may last for months, years or decades. However, symptoms dont occur every day. Episodes generally occur several times a year but can happen up to once or twice a month. […] The symptoms, time of day, frequency, severity and length of each episode are usually the same for any one person. But these factors can vary from person to person. […] Cyclic vomiting syndrome (CVS) involves sudden, repeated episodes of severe nausea and vomiting.
- #103 Cyclic Vomiting Syndrome: Practice Essentials, Pathophysiology and Etiology, Epidemiologyhttps://emedicine.medscape.com/article/933135-overview
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic. […] Most published series indicate that CVS lasts an average of 2.5-5.5 years, resolving in late childhood or early adolescence. A few patients continue to be symptomatic through adulthood. […] A survey by Abu-Arafeh et al found the mean ages of children with CVS, abdominal migraines, and migraine headaches to be 5.3 years, 10.3 years, and 11.5 years, respectively. This finding supports the developmental progression from vomiting to abdominal pain to headache. […] Although patients are well about 90% of the time, CVS can be medically and socially disabling. More than 50% of patients require intravenous (IV) fluids, compared with less than 1% of patients with rotavirus gastroenteritis. The average annual cost of testing, treatment, and absenteeism totals $17,000. Children miss an average of 24 school days per year and often need home tutoring or, occasionally, home schooling. Additionally, because of its frequency during times of excitement, CVS has ruined many birthdays, holidays, and vacations. […] In adults, substantial morbidity is associated with CVS, perhaps because of lack of awareness and resultant delays in diagnosis. In a study of 41 CVS patients, Fleisher found that 32% were completely disabled at the time of diagnosis.
- #104 FAQ: Cyclic Vomiting Syndrome | Ohio State Health & Discoveryhttps://health.osu.edu/health/general-health/faq-cyclic-vomiting-syndrome
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) characterized by recurrent episodes of severe nausea, vomiting and often abdominal pain. It can be accompanied by other symptoms, such as excessive sweating, hot and cold flashes, diarrhea and sometimes headaches. […] CVS begins abruptly and usually occurs out of the blue, lasting hours to several days or even a week. In between episodes, individuals have periods of normal health, without any symptoms or can have some nausea and occasional abdominal discomfort at baseline. These symptom-free intervals can last for weeks to months. […] However, if left untreated, people with CVS may experience longer and more frequent episodes, potentially leading to a condition called coalescent CVS, in which the typical normal or inter-episodic phase is lost.
- #105 Cyclic Vomiting Syndrome: Diagnostic Criteria and Insights into Long Term Treatment Outcomes – Practical Gastrohttps://practicalgastro.com/2015/01/05/cyclic-vomiting-syndrome-diagnostic-criteria-and-insights-into-long-term-treatment-outcomes/
Cyclic vomiting syndrome (CVS) in adults is a disorder characterized by recurrent abrupt bouts of nausea, vomiting and abdominal pain separated by variable periods of normal health. […] This alternating pattern of disease and disease-free periods distinguishes CVS from other disorders of nausea and vomiting. […] Adult patients typically have been symptomatic for a long time before diagnosis. Patients often remain undiagnosed for some time due to lack of recognition of this clinical entity with reports suggesting a delay in diagnosis for as long as 8-21 years following onset of the symptoms. […] Over time without appropriate specific treatment, CVS cycles slowly begin to coalesce and become closer together and this can confuse the presentation and suggest more of a chronic entity such as gastroparesis.
- #106 Cyclic Vomiting Syndrome | Symptoms, Diagnosis & Treatmenthttps://www.cincinnatichildrens.org/health/c/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is a condition of recurrent episodes of intense nausea and vomiting lasting hours to days separated by completely symptom-free periods. The cause is unknown but there appears to be an increased incidence in children who have a family or personal history of migraines. […] CVS occurs most commonly in children ages 3 to 7 years old but can occur at any age, including adulthood. […] There may or may not be a warning sign or trigger prior to the start of a cyclic vomiting episode. If there is a trigger or warning sign, it may occur within minutes to hours prior to the episode. […] During the vomiting episode, other symptoms may include: headache, nausea, fever, dizziness, abdominal pain, unable to eat, drink, or take medications, light or sound sensitivity, dehydration. […] Over time, most children do grow out of CVS.
- #107https://www.aurorahealthcare.org/services/gastroenterology-colorectal-surgery/cyclic-vomiting-syndrome
Many children outgrow cyclic vomiting syndrome by the time they reach adolescence. Its important to monitor your child while they are in a CVS episode, especially if theyre young and cant communicate their needs. Your child will need to maintain fluids. […] Recurrent vomiting in adults or children is an unpleasant and often debilitating symptom to manage, but most can lead normal lives, especially between CVS episodes. Children typically outgrow CVS, but some could experience episodes into adulthood.
- #108 About cyclic vomiting syndrome | Children’s Wisconsinhttps://childrenswi.org/medical-care/gastroenterology-liver-and-nutrition-program/conditions/cyclic-vomiting-syndrome
Relentless vomiting can lead to significant dehydration. Signs of dehydration include thirst, much less urination, a dry mouth, and irritability or difficulty staying awake. A child with symptoms of dehydration should see a health care provider immediately. […] Vomiting can cause severe dehydration that can be life threatening and lead to hospitalization. Cyclic vomiting attacks can last for days and be extremely debilitating for the child and disruptive to family life. On average, these children miss about three weeks of school annually and suffer from significant anxiety due to their condition. […] Many children will outgrow CVS around puberty, but about 75% will likely develop migraine headaches later in life. Some children develop chronic daily nausea.
- #109 About cyclic vomiting syndrome | Children’s Wisconsinhttps://childrenswi.org/medical-care/gastroenterology-liver-and-nutrition-program/conditions/cyclic-vomiting-syndrome
Relentless vomiting can lead to significant dehydration. Signs of dehydration include thirst, much less urination, a dry mouth, and irritability or difficulty staying awake. A child with symptoms of dehydration should see a health care provider immediately. […] Vomiting can cause severe dehydration that can be life threatening and lead to hospitalization. Cyclic vomiting attacks can last for days and be extremely debilitating for the child and disruptive to family life. On average, these children miss about three weeks of school annually and suffer from significant anxiety due to their condition. […] Many children will outgrow CVS around puberty, but about 75% will likely develop migraine headaches later in life. Some children develop chronic daily nausea.
- #110 Cyclic Vomiting Syndrome: Practice Essentials, Pathophysiology and Etiology, Epidemiologyhttps://emedicine.medscape.com/article/933135-overview
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic. […] Most published series indicate that CVS lasts an average of 2.5-5.5 years, resolving in late childhood or early adolescence. A few patients continue to be symptomatic through adulthood. […] A survey by Abu-Arafeh et al found the mean ages of children with CVS, abdominal migraines, and migraine headaches to be 5.3 years, 10.3 years, and 11.5 years, respectively. This finding supports the developmental progression from vomiting to abdominal pain to headache. […] Although patients are well about 90% of the time, CVS can be medically and socially disabling. More than 50% of patients require intravenous (IV) fluids, compared with less than 1% of patients with rotavirus gastroenteritis. The average annual cost of testing, treatment, and absenteeism totals $17,000. Children miss an average of 24 school days per year and often need home tutoring or, occasionally, home schooling. Additionally, because of its frequency during times of excitement, CVS has ruined many birthdays, holidays, and vacations. […] In adults, substantial morbidity is associated with CVS, perhaps because of lack of awareness and resultant delays in diagnosis. In a study of 41 CVS patients, Fleisher found that 32% were completely disabled at the time of diagnosis.
- #111 FAQ: Cyclic Vomiting Syndrome | Ohio State Health & Discoveryhttps://health.osu.edu/health/general-health/faq-cyclic-vomiting-syndrome
The severity and duration vary from person to person, but episodes for each individual are typically consistent. […] CVS is a chronic disorder that can be managed but doesnt go away. However, some seniors with CVS have outgrown vomiting and instead develop episodes of migraine headaches. A large proportion of children with CVS outgrow symptoms but develop migraine headaches or chronic abdominal pain. […] Medication and other treatments, like behavioral therapy and meditation, can help manage the symptoms of CVS. […] Cyclic vomiting syndrome is not a life-threatening condition. However, its important to note that severe episodes of vomiting can lead to complications like severe dehydration and acute kidney injury. Some patients can develop suicidal ideation, particularly if theyre unable to find a doctor who cares for patients with CVS.
- #112 Cyclic Vomiting Syndrome in 41 adults: the illness, the patients, and problems of management | BMC Medicine | Full Texthttps://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-3-20
Cyclic Vomiting Syndrome (CVS) is a disorder characterized by recurrent, stereotypic episodes of incapacitating nausea, vomiting and other symptoms, separated by intervals of comparative wellness. […] Age of onset ranged from 2 to 49 years. The duration of CVS at the time of consultation ranged from less than 1 year to 49 years. CVS episodes were stereotypic in respect of their hours of onset, symptomatology and length. Ninety-three percent of patients had recognizable prodromes. […] Deterioration in the course of CVS is indicated by coalescence of episodes in time. The prognosis of CVS is favorable in the majority of patients. […] The prodrome of a cyclic vomiting episode is important because it allows for attempts at aborting the emetic phase. Thirty-eight patients (93%) had recognizable prodromes.
- #113 Cyclic Vomiting Syndrome: Diagnostic Criteria and Insights into Long Term Treatment Outcomes – Practical Gastrohttps://practicalgastro.com/2015/01/05/cyclic-vomiting-syndrome-diagnostic-criteria-and-insights-into-long-term-treatment-outcomes/
Long term management is focused on reducing and actually preventing future hyperemesis episodes. […] The important message for our clinicians is that CVS can be presented to the patient as a potentially reversible disease: Following initial intensive treatment to achieve remission and after effectively addressing comorbidities, the dose of amitriptyline can be slowly tapered and even stopped over time.
- #114 Cyclic Vomiting Syndrome: Causes, Treatment, and Morehttps://www.healthline.com/health/cyclic-vomiting-syndrome
Cyclic vomiting syndrome (CVS) is a gastrointestinal condition. The disorder involves recurring, sudden episodes of nausea and vomiting without any specific cause. The symptoms can be severe, lasting for hours or days. […] The main symptom of CVS is recurrent episodes of severe vomiting and nausea. The nausea, along with dry heaving, usually persists after vomiting. […] Children with CVS often experience these episodes for several hours or days. Adults typically have less frequent episodes. However, the cycle of episodes may last longer. It can last for about a week. […] Other symptoms of CVS include fatigue, pale skin in people with lighter complexions, abdominal pain, diarrhea, dizziness, headache, fever, drooling, sensitivity to light (photophobia) or sound, heightened sensitivity to smell (hypersomnia), and fainting.
- #115 Cyclic Vomiting Syndrome | Symptoms, Diagnosis & Treatmenthttps://www.cincinnatichildrens.org/health/c/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is a condition of recurrent episodes of intense nausea and vomiting lasting hours to days separated by completely symptom-free periods. The cause is unknown but there appears to be an increased incidence in children who have a family or personal history of migraines. […] CVS occurs most commonly in children ages 3 to 7 years old but can occur at any age, including adulthood. […] There may or may not be a warning sign or trigger prior to the start of a cyclic vomiting episode. If there is a trigger or warning sign, it may occur within minutes to hours prior to the episode. […] During the vomiting episode, other symptoms may include: headache, nausea, fever, dizziness, abdominal pain, unable to eat, drink, or take medications, light or sound sensitivity, dehydration. […] Over time, most children do grow out of CVS.
- #116 Cyclic Vomiting Syndrome: Causes, Treatment, and Morehttps://www.healthline.com/health/cyclic-vomiting-syndrome
Cyclic vomiting syndrome (CVS) is a gastrointestinal condition. The disorder involves recurring, sudden episodes of nausea and vomiting without any specific cause. The symptoms can be severe, lasting for hours or days. […] The main symptom of CVS is recurrent episodes of severe vomiting and nausea. The nausea, along with dry heaving, usually persists after vomiting. […] Children with CVS often experience these episodes for several hours or days. Adults typically have less frequent episodes. However, the cycle of episodes may last longer. It can last for about a week. […] Other symptoms of CVS include fatigue, pale skin in people with lighter complexions, abdominal pain, diarrhea, dizziness, headache, fever, drooling, sensitivity to light (photophobia) or sound, heightened sensitivity to smell (hypersomnia), and fainting.
- #117 Cyclic Vomiting Syndrome: Practice Essentials, Pathophysiology and Etiology, Epidemiologyhttps://emedicine.medscape.com/article/933135-overview
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic. […] Most published series indicate that CVS lasts an average of 2.5-5.5 years, resolving in late childhood or early adolescence. A few patients continue to be symptomatic through adulthood. […] A survey by Abu-Arafeh et al found the mean ages of children with CVS, abdominal migraines, and migraine headaches to be 5.3 years, 10.3 years, and 11.5 years, respectively. This finding supports the developmental progression from vomiting to abdominal pain to headache. […] Although patients are well about 90% of the time, CVS can be medically and socially disabling. More than 50% of patients require intravenous (IV) fluids, compared with less than 1% of patients with rotavirus gastroenteritis. The average annual cost of testing, treatment, and absenteeism totals $17,000. Children miss an average of 24 school days per year and often need home tutoring or, occasionally, home schooling. Additionally, because of its frequency during times of excitement, CVS has ruined many birthdays, holidays, and vacations. […] In adults, substantial morbidity is associated with CVS, perhaps because of lack of awareness and resultant delays in diagnosis. In a study of 41 CVS patients, Fleisher found that 32% were completely disabled at the time of diagnosis.
- #118 Cyclic Vomiting Syndrome: Practice Essentials, Pathophysiology and Etiology, Epidemiologyhttps://emedicine.medscape.com/article/933135-overview
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic. […] Most published series indicate that CVS lasts an average of 2.5-5.5 years, resolving in late childhood or early adolescence. A few patients continue to be symptomatic through adulthood. […] A survey by Abu-Arafeh et al found the mean ages of children with CVS, abdominal migraines, and migraine headaches to be 5.3 years, 10.3 years, and 11.5 years, respectively. This finding supports the developmental progression from vomiting to abdominal pain to headache. […] Although patients are well about 90% of the time, CVS can be medically and socially disabling. More than 50% of patients require intravenous (IV) fluids, compared with less than 1% of patients with rotavirus gastroenteritis. The average annual cost of testing, treatment, and absenteeism totals $17,000. Children miss an average of 24 school days per year and often need home tutoring or, occasionally, home schooling. Additionally, because of its frequency during times of excitement, CVS has ruined many birthdays, holidays, and vacations. […] In adults, substantial morbidity is associated with CVS, perhaps because of lack of awareness and resultant delays in diagnosis. In a study of 41 CVS patients, Fleisher found that 32% were completely disabled at the time of diagnosis.
- #119 About cyclic vomiting syndrome | Children’s Wisconsinhttps://childrenswi.org/medical-care/gastroenterology-liver-and-nutrition-program/conditions/cyclic-vomiting-syndrome
Relentless vomiting can lead to significant dehydration. Signs of dehydration include thirst, much less urination, a dry mouth, and irritability or difficulty staying awake. A child with symptoms of dehydration should see a health care provider immediately. […] Vomiting can cause severe dehydration that can be life threatening and lead to hospitalization. Cyclic vomiting attacks can last for days and be extremely debilitating for the child and disruptive to family life. On average, these children miss about three weeks of school annually and suffer from significant anxiety due to their condition. […] Many children will outgrow CVS around puberty, but about 75% will likely develop migraine headaches later in life. Some children develop chronic daily nausea.
- #120 Cyclic Vomiting Syndrome: Practice Essentials, Pathophysiology and Etiology, Epidemiologyhttps://emedicine.medscape.com/article/933135-overview
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic. […] Most published series indicate that CVS lasts an average of 2.5-5.5 years, resolving in late childhood or early adolescence. A few patients continue to be symptomatic through adulthood. […] A survey by Abu-Arafeh et al found the mean ages of children with CVS, abdominal migraines, and migraine headaches to be 5.3 years, 10.3 years, and 11.5 years, respectively. This finding supports the developmental progression from vomiting to abdominal pain to headache. […] Although patients are well about 90% of the time, CVS can be medically and socially disabling. More than 50% of patients require intravenous (IV) fluids, compared with less than 1% of patients with rotavirus gastroenteritis. The average annual cost of testing, treatment, and absenteeism totals $17,000. Children miss an average of 24 school days per year and often need home tutoring or, occasionally, home schooling. Additionally, because of its frequency during times of excitement, CVS has ruined many birthdays, holidays, and vacations. […] In adults, substantial morbidity is associated with CVS, perhaps because of lack of awareness and resultant delays in diagnosis. In a study of 41 CVS patients, Fleisher found that 32% were completely disabled at the time of diagnosis.
- #121 Cyclic Vomiting Syndrome: Causes, Treatment, and Morehttps://www.healthline.com/health/cyclic-vomiting-syndrome
Cyclic vomiting syndrome (CVS) is a gastrointestinal condition. The disorder involves recurring, sudden episodes of nausea and vomiting without any specific cause. The symptoms can be severe, lasting for hours or days. […] The main symptom of CVS is recurrent episodes of severe vomiting and nausea. The nausea, along with dry heaving, usually persists after vomiting. […] Children with CVS often experience these episodes for several hours or days. Adults typically have less frequent episodes. However, the cycle of episodes may last longer. It can last for about a week. […] Other symptoms of CVS include fatigue, pale skin in people with lighter complexions, abdominal pain, diarrhea, dizziness, headache, fever, drooling, sensitivity to light (photophobia) or sound, heightened sensitivity to smell (hypersomnia), and fainting.
- #122 Cyclic Vomiting Syndrome: Practice Essentials, Pathophysiology and Etiology, Epidemiologyhttps://emedicine.medscape.com/article/933135-overview
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic. […] Most published series indicate that CVS lasts an average of 2.5-5.5 years, resolving in late childhood or early adolescence. A few patients continue to be symptomatic through adulthood. […] A survey by Abu-Arafeh et al found the mean ages of children with CVS, abdominal migraines, and migraine headaches to be 5.3 years, 10.3 years, and 11.5 years, respectively. This finding supports the developmental progression from vomiting to abdominal pain to headache. […] Although patients are well about 90% of the time, CVS can be medically and socially disabling. More than 50% of patients require intravenous (IV) fluids, compared with less than 1% of patients with rotavirus gastroenteritis. The average annual cost of testing, treatment, and absenteeism totals $17,000. Children miss an average of 24 school days per year and often need home tutoring or, occasionally, home schooling. Additionally, because of its frequency during times of excitement, CVS has ruined many birthdays, holidays, and vacations. […] In adults, substantial morbidity is associated with CVS, perhaps because of lack of awareness and resultant delays in diagnosis. In a study of 41 CVS patients, Fleisher found that 32% were completely disabled at the time of diagnosis.
- #123 Cyclic Vomiting Syndrome: Recognition and Guidelines for Treatment | UPMC Physician Resourceshttps://www.upmcphysicianresources.com/news/011822-cyclic-vomiting-syndrome
Nausea and vomiting have many etiologies, and cyclic vomiting syndrome (CVS) is not the first diagnosis that comes to mind for an adult presenting to the emergency department. […] Adults with CVS almost always receive fragmented care, and a diagnostic delay of five to six years from the onset of symptoms is typical. […] CVS is characterized by four phases. Each attack begins with a prodromic phase, followed by an emetic phase, and then a recovery phase. Between episodes, there is a well phase, during which the patient is typically, but not always, asymptomatic. […] Sweating and nausea are common during the prodrome phase, which is similar to the prodrome experienced by migraine sufferers. […] Episodes often begin suddenly in the early morning. Patients describe this sudden onset as feeling like a switch flipped, which suggests a nervous system state change.
- #124 Cyclic Vomiting Syndrome: Diagnostic Criteria and Insights into Long Term Treatment Outcomes – Practical Gastrohttps://practicalgastro.com/2015/01/05/cyclic-vomiting-syndrome-diagnostic-criteria-and-insights-into-long-term-treatment-outcomes/
Cyclic vomiting syndrome (CVS) in adults is a disorder characterized by recurrent abrupt bouts of nausea, vomiting and abdominal pain separated by variable periods of normal health. […] This alternating pattern of disease and disease-free periods distinguishes CVS from other disorders of nausea and vomiting. […] Adult patients typically have been symptomatic for a long time before diagnosis. Patients often remain undiagnosed for some time due to lack of recognition of this clinical entity with reports suggesting a delay in diagnosis for as long as 8-21 years following onset of the symptoms. […] Over time without appropriate specific treatment, CVS cycles slowly begin to coalesce and become closer together and this can confuse the presentation and suggest more of a chronic entity such as gastroparesis.
- #125 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
Most people with cyclic vomiting syndrome have normal intelligence, although some affected people have developmental delay or intellectual disability. Autism spectrum disorder, which affects communication and social interaction, have also been associated with cyclic vomiting syndrome. Additionally, muscle weakness (myopathy) and seizures are possible. People with any of these additional features are said to have cyclic vomiting syndrome plus.
- #126 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
Most people with cyclic vomiting syndrome have normal intelligence, although some affected people have developmental delay or intellectual disability. Autism spectrum disorder, which affects communication and social interaction, have also been associated with cyclic vomiting syndrome. Additionally, muscle weakness (myopathy) and seizures are possible. People with any of these additional features are said to have cyclic vomiting syndrome plus.
- #127 Cyclic Vomiting Syndrome Causes, Symptoms, Diet, Treatmenthttps://www.medicinenet.com/cyclic_vomiting_syndrome_cvs/article.htm
The prognosis for CVS varies. Patients with complications and weak responses to treatment have a fair prognosis while others may respond well and have a good prognosis. In general, CVS lasts about two and a half to five and a half years, resolving late childhood or early adolescence. Some patients go on to develop migraine headaches, and a few patients have CVS extend into adulthood. Patients with a diagnosis of cyclic vomiting syndrome plus have a prognosis usually ranging from fair to poor.
- #128 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
If the condition is not treated, episodes usually occur four to 12 times per year. Between attacks, vomiting is absent, and nausea is either absent or much reduced. However, many affected people experience other symptoms during and between episodes, including pain, lethargy, digestive disorders such as gastroesophageal reflux and irritable bowel syndrome, and fainting spells (syncope). People with cyclic vomiting syndrome are also more likely than people without the disorder to experience depression, anxiety, and panic disorder. It is unclear whether these health conditions are directly related to nausea and vomiting. […] Cyclic vomiting syndrome is often considered to be a variant of migraines, which are severe headaches often associated with pain, nausea, vomiting, and extreme sensitivity to light and sound. Cyclic vomiting syndrome is likely the same as or closely related to a condition called abdominal migraine, which is characterized by attacks of stomach pain and cramping. Attacks of nausea, vomiting, or abdominal pain in childhood may be replaced by migraine headaches as an affected person gets older. Many people with cyclic vomiting syndrome or abdominal migraine have a family history of migraines.
- #129 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
If the condition is not treated, episodes usually occur four to 12 times per year. Between attacks, vomiting is absent, and nausea is either absent or much reduced. However, many affected people experience other symptoms during and between episodes, including pain, lethargy, digestive disorders such as gastroesophageal reflux and irritable bowel syndrome, and fainting spells (syncope). People with cyclic vomiting syndrome are also more likely than people without the disorder to experience depression, anxiety, and panic disorder. It is unclear whether these health conditions are directly related to nausea and vomiting. […] Cyclic vomiting syndrome is often considered to be a variant of migraines, which are severe headaches often associated with pain, nausea, vomiting, and extreme sensitivity to light and sound. Cyclic vomiting syndrome is likely the same as or closely related to a condition called abdominal migraine, which is characterized by attacks of stomach pain and cramping. Attacks of nausea, vomiting, or abdominal pain in childhood may be replaced by migraine headaches as an affected person gets older. Many people with cyclic vomiting syndrome or abdominal migraine have a family history of migraines.
- #130 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
If the condition is not treated, episodes usually occur four to 12 times per year. Between attacks, vomiting is absent, and nausea is either absent or much reduced. However, many affected people experience other symptoms during and between episodes, including pain, lethargy, digestive disorders such as gastroesophageal reflux and irritable bowel syndrome, and fainting spells (syncope). People with cyclic vomiting syndrome are also more likely than people without the disorder to experience depression, anxiety, and panic disorder. It is unclear whether these health conditions are directly related to nausea and vomiting. […] Cyclic vomiting syndrome is often considered to be a variant of migraines, which are severe headaches often associated with pain, nausea, vomiting, and extreme sensitivity to light and sound. Cyclic vomiting syndrome is likely the same as or closely related to a condition called abdominal migraine, which is characterized by attacks of stomach pain and cramping. Attacks of nausea, vomiting, or abdominal pain in childhood may be replaced by migraine headaches as an affected person gets older. Many people with cyclic vomiting syndrome or abdominal migraine have a family history of migraines.
- #131 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
If the condition is not treated, episodes usually occur four to 12 times per year. Between attacks, vomiting is absent, and nausea is either absent or much reduced. However, many affected people experience other symptoms during and between episodes, including pain, lethargy, digestive disorders such as gastroesophageal reflux and irritable bowel syndrome, and fainting spells (syncope). People with cyclic vomiting syndrome are also more likely than people without the disorder to experience depression, anxiety, and panic disorder. It is unclear whether these health conditions are directly related to nausea and vomiting. […] Cyclic vomiting syndrome is often considered to be a variant of migraines, which are severe headaches often associated with pain, nausea, vomiting, and extreme sensitivity to light and sound. Cyclic vomiting syndrome is likely the same as or closely related to a condition called abdominal migraine, which is characterized by attacks of stomach pain and cramping. Attacks of nausea, vomiting, or abdominal pain in childhood may be replaced by migraine headaches as an affected person gets older. Many people with cyclic vomiting syndrome or abdominal migraine have a family history of migraines.
- #132 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
The most common precipitating event is infection (41%), particularly chronic sinusitis. […] Approximately 68% of families are able to identify events that appear to precipitate a patient’s episode. […] The terms cyclic vomiting syndrome and abdominal migraine have often been used interchangeably because of the considerable overlap in clinical criteria. […] Because 80% of children with CVS have abdominal pain, and 50% of those with abdominal pain vomit, many children can be diagnosed with either CVS or abdominal migraine. […] The following 3 additional criteria help strengthen the diagnosis of CVS: Negative screening test results to exclude common GI, hepatobiliary, renal, metabolic, and endocrine disorders; Subsequent development of migraine headaches; A positive response to antimigraine medications. […] Clinical features of CVS are summarized in Table 2 below.
- #133 Cyclic Vomiting Syndrome Clinical Presentation: Historyhttps://emedicine.medscape.com/article/933135-clinical
The most common precipitating event is infection (41%), particularly chronic sinusitis. […] Approximately 68% of families are able to identify events that appear to precipitate a patient’s episode. […] The terms cyclic vomiting syndrome and abdominal migraine have often been used interchangeably because of the considerable overlap in clinical criteria. […] Because 80% of children with CVS have abdominal pain, and 50% of those with abdominal pain vomit, many children can be diagnosed with either CVS or abdominal migraine. […] The following 3 additional criteria help strengthen the diagnosis of CVS: Negative screening test results to exclude common GI, hepatobiliary, renal, metabolic, and endocrine disorders; Subsequent development of migraine headaches; A positive response to antimigraine medications. […] Clinical features of CVS are summarized in Table 2 below.
- #134 Cyclic Vomiting Syndrome: Recognition and Guidelines for Treatment | UPMC Physician Resourceshttps://www.upmcphysicianresources.com/news/011822-cyclic-vomiting-syndrome
CVS episodes are typically accompanied by tachycardia, dizziness, salivation, and paleness of the skin. During the emetic phase, the patient experiences severe nausea and vomits or retches repeatedly. Stomach pain may accompany vomiting. The emetic phase can last for hours or days. […] The recovery phase begins when vomiting and retching stop and lasts until normal energy and appetite return. […] Patients with CVS experience multiple episodes of vomiting each year. […] The diagnostic criteria known as the Rome IV criteria define the cyclic nature of CVS as two acute-onset episodes within six months that are at least a week apart and each lasts for less than seven days with an absence of vomiting between episodes. […] CVS has many features in common with migraine, epilepsy, and panic disorder.
- #135 Cyclic Vomiting Syndrome: Recognition and Guidelines for Treatment | UPMC Physician Resourceshttps://www.upmcphysicianresources.com/news/011822-cyclic-vomiting-syndrome
These similarities suggest a common neurogenic etiology and, moreover, suggest that patients with CVS could benefit from trials of therapies that are currently available for the treatment of migraines, seizures, or panic disorder. […] Most patients respond to readily available medications. […] For prophylaxis, tricyclic antidepressants, such as amitriptyline, are strongly recommended as a first-line medication in patients with moderate-to-severe CVS. […] When patients present to the emergency department during a CVS episode, a combination of anti-emetics, analgesics, and sedation is likely to yield relief. […] Recognition of CVS is key to improving the lives of these patients. CVS is treatable in most patients with drugs that are widely available and known to be well-tolerated.
- #136 Cyclic vomiting syndrome | UM Health-Sparrowhttps://www.uofmhealthsparrow.org/departments-conditions/conditions/cyclic-vomiting-syndrome
Cyclic vomiting syndrome is characterized by episodes of severe vomiting that have no apparent cause. Episodes can last for hours or days and alternate with symptom-free periods. Episodes are similar, meaning that they tend to start at the same time of day, last the same length of time, and occur with the same symptoms and intensity. […] The symptoms of cyclic vomiting syndrome often begin in the morning. Signs and symptoms include: Three or more recurrent episodes of vomiting that start around the same time and last for a similar length of time. Varying intervals of generally normal health without nausea between episodes. Intense nausea and sweating before an episode starts. […] Other signs and symptoms during a vomiting episode may include: Abdominal pain, Diarrhea, Dizziness, Sensitivity to light, Headache, Retching or gagging.
- #137 Cyclic Vomiting Syndrome: Symptoms, Causes & Triggers, Treatmenthttps://my.clevelandclinic.org/health/diseases/14894-cyclic-vomiting-syndrome
Cyclic vomiting syndrome is when you experience cycles of severe nausea, vomiting and exhaustion that can last from a few hours up to a few days. Episodes can last from a few hours to several days. They can be so severe that you need to stay in bed. You may need to go to the emergency room (ER) or hospital to get IV fluids to prevent dehydration. […] CVS may last for months, years or decades. However, symptoms dont occur every day. Episodes generally occur several times a year but can happen up to once or twice a month. […] The symptoms, time of day, frequency, severity and length of each episode are usually the same for any one person. But these factors can vary from person to person. […] Cyclic vomiting syndrome (CVS) involves sudden, repeated episodes of severe nausea and vomiting.
- #138 Symptoms & Causes of Cyclic Vomiting Syndrome – NIDDKhttps://www.niddk.nih.gov/health-information/digestive-diseases/cyclic-vomiting-syndrome/symptoms-causes
The symptoms will vary as you go through the four phases of cyclic vomiting syndrome: During the prodrome phase, you feel an episode coming on. Often marked by intense sweating and nausea with or without pain in your abdomen this phase can last from a few minutes to several hours. Your skin may look unusually pale. […] The main symptoms of this phase are severe nausea, vomiting, and retching. At the peak of this phase, you may vomit several times an hour. […] Recovery begins when you stop vomiting and retching and you feel less nauseated. You may feel better gradually or quickly. The recovery phase ends when your nausea stops and your healthy skin color, appetite, and energy return. […] The well phase happens between episodes. You have no symptoms during this phase.
- #139 FAQ: Cyclic Vomiting Syndrome | Ohio State Health & Discoveryhttps://health.osu.edu/health/general-health/faq-cyclic-vomiting-syndrome
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) characterized by recurrent episodes of severe nausea, vomiting and often abdominal pain. It can be accompanied by other symptoms, such as excessive sweating, hot and cold flashes, diarrhea and sometimes headaches. […] CVS begins abruptly and usually occurs out of the blue, lasting hours to several days or even a week. In between episodes, individuals have periods of normal health, without any symptoms or can have some nausea and occasional abdominal discomfort at baseline. These symptom-free intervals can last for weeks to months. […] However, if left untreated, people with CVS may experience longer and more frequent episodes, potentially leading to a condition called coalescent CVS, in which the typical normal or inter-episodic phase is lost.
- #140 Cyclic vomiting syndrome: A GI primer | MDedgehttps://mdedge.com/gihepnews/article/221281/mixed-topics/cyclic-vomiting-syndrome-gi-primer
Cyclic vomiting syndrome (CVS) is a chronic disorder of gut-brain interaction (DGBI) and is characterized by recurrent episodes of severe nausea, vomiting, and often, abdominal pain. Patients are usually asymptomatic in between episodes. […] Most patients (~ 93%) have a prodromal phase. Symptoms during this phase can include nausea, abdominal pain, diaphoresis, fatigue, weakness, hot flashes, chills, shivering, increased thirst, loss of appetite, burping, lightheadedness, and paresthesia. Some patients report a sense of impending doom and many have symptoms consistent with panic. If untreated, this progresses to the emetic phase and patients have unrelenting nausea, retching, vomiting, and other symptoms. During an episode, patients may vomit up to 20 times per hour and the episode may last several hours to days. During this phase, patients are sometimes described as being in a âconscious comaâ and exhibit lethargy, listlessness, withdrawal, and sometimes disorientation.
- #141 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age. […] The episodes of nausea, vomiting, and lethargy last anywhere from an hour to 10 days. An affected person may vomit several times per hour, potentially leading to a dangerous loss of fluids (dehydration). Additional symptoms can include unusually pale skin (pallor), abdominal pain, diarrhea, headache, fever, and an increased sensitivity to light (photophobia) or to sound (phonophobia). In most affected people, the signs and symptoms of each attack are quite similar. These attacks can be debilitating, making it difficult for an affected person to go to work or school. […] Episodes of nausea, vomiting, and lethargy can occur regularly or apparently at random, or can be triggered by a variety of factors. The most common triggers are emotional excitement and infections. Other triggers can include periods without eating (fasting), temperature extremes, lack of sleep, overexertion, allergies, ingesting certain foods or alcohol, and menstruation.
- #142 Cyclic vomiting syndrome – Hancock Healthhttps://www.hancockhealth.org/mayo-health-library/cyclic-vomiting-syndrome/
Continued vomiting may cause severe dehydration that can be life-threatening. Call your doctor if you or your child is showing symptoms of dehydration, such as: Excess thirst or dry mouth, Less urination, Dry skin, Sunken eyes or cheeks, No tears when crying, Exhaustion and listlessness. […] Cyclic vomiting syndrome can cause these complications: Dehydration. Excessive vomiting causes the body to lose water quickly. Severe cases of dehydration may need to be treated in the hospital. Injury to the food tube. The stomach acid that comes up with the vomit can damage the tube that connects the mouth and stomach (esophagus). Sometimes the esophagus becomes so irritated it bleeds. Tooth decay. The acid in vomit can corrode tooth enamel. […] Many people know what triggers their cyclic vomiting episodes. Avoiding those triggers can reduce the frequency of episodes.
- #143 About cyclic vomiting syndrome | Children’s Wisconsinhttps://childrenswi.org/medical-care/gastroenterology-liver-and-nutrition-program/conditions/cyclic-vomiting-syndrome
Relentless vomiting can lead to significant dehydration. Signs of dehydration include thirst, much less urination, a dry mouth, and irritability or difficulty staying awake. A child with symptoms of dehydration should see a health care provider immediately. […] Vomiting can cause severe dehydration that can be life threatening and lead to hospitalization. Cyclic vomiting attacks can last for days and be extremely debilitating for the child and disruptive to family life. On average, these children miss about three weeks of school annually and suffer from significant anxiety due to their condition. […] Many children will outgrow CVS around puberty, but about 75% will likely develop migraine headaches later in life. Some children develop chronic daily nausea.
- #144 Cyclic Vomiting Syndrome: Practice Essentials, Pathophysiology and Etiology, Epidemiologyhttps://emedicine.medscape.com/article/933135-overview
Cyclic vomiting syndrome (CVS) is characterized by recurrent, discrete, stereotypical episodes of rapid-fire vomiting between varying periods of completely normal health. This on-and-off stereotypical pattern of vomiting is nearly pathognomonic. […] Most published series indicate that CVS lasts an average of 2.5-5.5 years, resolving in late childhood or early adolescence. A few patients continue to be symptomatic through adulthood. […] A survey by Abu-Arafeh et al found the mean ages of children with CVS, abdominal migraines, and migraine headaches to be 5.3 years, 10.3 years, and 11.5 years, respectively. This finding supports the developmental progression from vomiting to abdominal pain to headache. […] Although patients are well about 90% of the time, CVS can be medically and socially disabling. More than 50% of patients require intravenous (IV) fluids, compared with less than 1% of patients with rotavirus gastroenteritis. The average annual cost of testing, treatment, and absenteeism totals $17,000. Children miss an average of 24 school days per year and often need home tutoring or, occasionally, home schooling. Additionally, because of its frequency during times of excitement, CVS has ruined many birthdays, holidays, and vacations. […] In adults, substantial morbidity is associated with CVS, perhaps because of lack of awareness and resultant delays in diagnosis. In a study of 41 CVS patients, Fleisher found that 32% were completely disabled at the time of diagnosis.
- #145 Cyclic vomiting syndrome: MedlinePlus GeneticsLockhttps://medlineplus.gov/genetics/condition/cyclic-vomiting-syndrome/
If the condition is not treated, episodes usually occur four to 12 times per year. Between attacks, vomiting is absent, and nausea is either absent or much reduced. However, many affected people experience other symptoms during and between episodes, including pain, lethargy, digestive disorders such as gastroesophageal reflux and irritable bowel syndrome, and fainting spells (syncope). People with cyclic vomiting syndrome are also more likely than people without the disorder to experience depression, anxiety, and panic disorder. It is unclear whether these health conditions are directly related to nausea and vomiting. […] Cyclic vomiting syndrome is often considered to be a variant of migraines, which are severe headaches often associated with pain, nausea, vomiting, and extreme sensitivity to light and sound. Cyclic vomiting syndrome is likely the same as or closely related to a condition called abdominal migraine, which is characterized by attacks of stomach pain and cramping. Attacks of nausea, vomiting, or abdominal pain in childhood may be replaced by migraine headaches as an affected person gets older. Many people with cyclic vomiting syndrome or abdominal migraine have a family history of migraines.
- #146 Cyclic Vomiting Syndrome in 41 adults: the illness, the patients, and problems of management | BMC Medicine | Full Texthttps://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-3-20
Cyclic Vomiting Syndrome (CVS) is a disorder characterized by recurrent, stereotypic episodes of incapacitating nausea, vomiting and other symptoms, separated by intervals of comparative wellness. […] Age of onset ranged from 2 to 49 years. The duration of CVS at the time of consultation ranged from less than 1 year to 49 years. CVS episodes were stereotypic in respect of their hours of onset, symptomatology and length. Ninety-three percent of patients had recognizable prodromes. […] Deterioration in the course of CVS is indicated by coalescence of episodes in time. The prognosis of CVS is favorable in the majority of patients. […] The prodrome of a cyclic vomiting episode is important because it allows for attempts at aborting the emetic phase. Thirty-eight patients (93%) had recognizable prodromes.