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• #1 De Quervain tenosynovitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/de-quervain-tenosynovitis/symptoms-causes/syc-20371332

  De Quervain tenosynovitis (dih-kwer-VAIN ten-oh-sine-oh-VIE-tis) is a painful condition affecting the tendons on the thumb side of the wrist. […] Although the exact cause of de Quervain tenosynovitis isn’t known, any activity that relies on repetitive hand or wrist movement such as working in the garden, playing golf or racket sports, or lifting a baby can make it worse. […] Chronic overuse, such as repeating a particular hand motion day after day, may irritate the covering around the tendons. If the covering becomes irritated, the tendons can thicken and swell. This thickening and swelling restrict the movement of the tendons through the small tunnel that connects them to the base of the thumb. […] Other causes of de Quervain tenosynovitis include: Inflammatory arthritis, such as rheumatoid arthritis. Direct injury to the wrist or tendon, which may cause scar tissue that restricts movement of the tendons. Fluid retention, such as from changes in hormones during pregnancy.

• #2 De Quervain Tenosynovitis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK442005/

  De Quervain tenosynovitis, named after Swiss surgeon Fritz de Quervain, is a condition that involves tendon entrapment affecting the first dorsal compartment of the wrist. […] While the exact cause of de Quervain tenosynovitis is unclear, it has been attributed to myxoid degeneration with fibrous tissue deposits and increased vascularity rather than acute inflammation of the synovial lining. This deposition results in the thickening of the tendon sheath, painfully entrapping the abductor pollicis longus and extensor pollicis brevis tendons. It is associated with repetitive wrist movements, specifically requiring thumb radial abduction, simultaneous extension, and radial wrist deviation. […] Some possible etiologies for the disease include acute injury to the wrist, increased frictional forces to the wrist by forceful movements of the wrist and the thumb, pathogenic causes, inflammatory ailments, and anatomical variations in the first dorsal compartment.

• #3 De Quervain’s Disease: A Discourse on Etiology, Diagnosis, and Treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10208847/

  De Quervains tenosynovitis, also known as De Quervains disease (DQD), is a painful condition that affects the tendons on the lateral side of the wrist. It is caused by inflammation of the tendons that control the movement of the thumb, specifically the abductor pollicis longus (APL) and extensor pollicis brevis (EPB). […] The preliminary literature suggests that DQD results from myxoid degeneration rather than an underlying inflammatory process. On the contrary, present-day investigation emphasizes the inflammatory markers that may cause a predisposition to this condition. […] The exact etiology of DQD is a subject of investigation; many prevailing theories have arisen since De Quervain first postulated its origin in his preliminary paper. […] Several explanations for the underlying cause of DQD have been proposed since its discovery.

• #4 De Quervain’s Tenosynovitis > Fact Sheets > Yale Medicine

  https://www.yalemedicine.org/conditions/de-quervains-tenosynovitis

  Though the name sounds exotic, de Quervains tenosynovitisa condition caused by constriction or pinching of the wrist tendons at the base of the thumbcan arise from such simple tasks as lifting a laundry basket, putting away groceries, or even lifting babies. […] Noting that de Quervains is most common in women between the ages of 30 and 50, J. Grant Thomson, MD, director of Yale Medicines Hand Microsurgery Program, says he sees it most often in women, but usually cannot identify a specific cause. The condition may be associated with repetitive stress, pregnancy, or rheumatoid arthritis, but often just appears for no apparent reason he says. […] More research is needed to understand the exact cause of de Quervain’s tenosynovitis. […] The compression causes pain with activities that rely on repetitive hand or wrist motion.

• #5 De Quervain Tenosynovitis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK442005/

  De Quervain tenosynovitis, named after Swiss surgeon Fritz de Quervain, is a condition that involves tendon entrapment affecting the first dorsal compartment of the wrist. […] While the exact cause of de Quervain tenosynovitis is unclear, it has been attributed to myxoid degeneration with fibrous tissue deposits and increased vascularity rather than acute inflammation of the synovial lining. This deposition results in the thickening of the tendon sheath, painfully entrapping the abductor pollicis longus and extensor pollicis brevis tendons. It is associated with repetitive wrist movements, specifically requiring thumb radial abduction, simultaneous extension, and radial wrist deviation. […] Some possible etiologies for the disease include acute injury to the wrist, increased frictional forces to the wrist by forceful movements of the wrist and the thumb, pathogenic causes, inflammatory ailments, and anatomical variations in the first dorsal compartment.

• #6 de Quervain tendinopathy – UpToDate

  https://www.uptodate.com/contents/de-quervain-tendinopathy

  de Quervain tendinopathy affects the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons in the first extensor compartment at the styloid process of the radius. It is characterized by pain and tenderness at the radial side of the wrist. Although de Quervain tendinopathy is often attributed to overuse or repetitive movements of the wrist or thumb, the cause is generally unknown. […] The etiology of de Quervain tendinopathy is not well-understood. In the past, it was frequently attributed to occupational or repetitive activities involving postures that maintain the thumb in extension and abduction. As an example, it has been thought that new mothers are at risk postpartum due to repetitive motion of hands required to lift and hold newborns. Hormonal causes and fluid retention are another plausible explanation. The evidence to support etiologic hypotheses is limited and is largely based on observational data. The histopathology does not demonstrate inflammation but rather myxoid degeneration (disorganized collagen and increased cellular matrix) in patients referred for surgery.

• #7 De Quervain’s Disease: A Discourse on Etiology, Diagnosis, and Treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10208847/

  Inflammatory mediators are molecules released during the inflammatory response and play a crucial role in the pathogenesis of DQD by promoting the recruitment of immune cells to the site of inflammation, increasing blood vessel permeability, and inducing pain. […] The presence of inflammatory activity within DQD specimens has been demonstrated in multiple studies. […] Some studies suggest inflammation may be a confounding variable that cloaks the true pathological nature of this condition. […] DQD has been investigated from multifarious paradigms, providing insights into the factors contributing to its pathogenesis.

• #8 The Most Common Cause of De Quervain’s Tenosynovitis

  https://www.spencerhospital.org/blog/health-wellness/the-most-common-cause-of-de-quervains-tenosynovitis/

  The most common cause of de Quervains Tenosynovitis is a chronic overuse of the wrist that results in pain at the base of the thumb. […] Those tendons go through a tunnel and with repetitive motion, the tunnel becomes inflamed, which makes the opening smaller for the two tendons to slide through and results in swelling and pain.

• #9 de Quervain’s Tenosynovitis: Symptoms, Causes, Diagnosis, Treatment

  https://www.webmd.com/rheumatoid-arthritis/de-quervains-disease

  De Quervain’s tenosynovitis is inflammation around the tendons in your thumb that leads to painful swelling. […] Doctors often dont know why you get de Quervain’s tenosynovitis. But it does result from: A direct blow to the thumb, Inflammatory conditions like rheumatoid arthritis, Overuse in hobbies, Repetitive workplace tasks. […] The most common cause is repetitive activities that overwork those tendons.

• #10 De Quervain’s Tenosynovitis: Chronic Wrist Pain | HSS

  https://www.hss.edu/condition-list_de-quervain-syndrome.asp

  De Quervain’s tenosynovitis is inflammation of the tendon that runs down the forearm, through the wrist and to the thumb. […] This injury is caused by repetitive strain on the tendon due to frequent, awkward positioning of the wrist and/or thumb. […] It can be brought on by repetition of many everyday activities, including: computer keyboard use, fly fishing, golfing, hammering, knitting, lifting and holding babies, skiing, texting.

• #11 De Quervain’s Tenosynovitis – Causes, Symptoms & Treatment

  https://www.melbournehandtherapy.com.au/conditions-treated/dequervains-tenosynovitis/

  De Quervains tenosynovitis/disease (DQV), is an overuse condition that results in pain on the radial or thumb side of the wrist. […] DQV is a common condition that is generally linked to overuse and work related, repetitive movements. There are many activities in our daily lives that may result in the development of DQV. […] Increased use of mobile phones, ipads, gaming consoles. […] Pregnancy increased fluid can result in more pressure at the wrist. […] New parents/grandparents repetitive lifting with thumbs extended, patting, prolonged holding during feeds with wrist in end range flexion. […] Commencement of high intensity and jarring workouts kettlebells, burpees, push up challenges, etc. […] Manual workers or DIY enthusiasts increased repetitive tasks, eg: painting, moving bricks, etc. This can include a one off day of intense work. […] Underlying chronic inflammatory conditions, eg: osteo or rheumatoid arthritis. […] Direct trauma to the area. […] Scar tissue from wrist fractures, leading to reduced glide of the EPB/APL tendons.

• #12 De Quervain’s Tenosynovitis | Memorial Sloan Kettering Cancer Center

  https://www.mskcc.org/cancer-care/patient-education/de-quervain-tenosynovitis

  De Quervains tenosynovitis is a common and painful condition that can affect the tendons in your wrist. […] Some causes of de Quervains tenosynovitis are: Doing the same wrist movements over and over, such as: Typing. Knitting. Using a hammer. Holding a baby for a long time. Carrying heavy grocery bags. […] Strain or injury to your wrist area. […] Health problems that cause swelling throughout your body, such as rheumatoid arthritis (ROO-muh-TOYD ar-THRY-tis). Rheumatoid arthritis is a disorder that causes swollen and painful joints.

• #13 De Quervain’s Tenosynovitis Causes, Symptoms, Treatment, Medications, Prevention

  https://www.medicinenet.com/de_quervains_tenosynovitis/article.htm

  De Quervain’s tenosynovitis can be brought on by simple strain injury to the extensor pollicis longus and abductor pollicis tendons (tendinitis). Often this form of tendinitis is a result of repetitive motion injury. Typical causes of de Quervain’s tenosynovitis include stresses such as lifting young children into car seats, lifting heavy grocery bags by the loops, and lifting gardening pots up and into place. […] Risk factors for de Quervain’s tenosynovitis include the following: Being female, Age over 40, African ethnicity/descent, Pregnancy. […] De Quervain’s tenosynovitis can be prevented by avoiding activities that stress the wrist and avoiding repetitive motion injuries.

• #14 De Quervain tenosynovitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/de-quervain-tenosynovitis/symptoms-causes/syc-20371332

  De Quervain tenosynovitis (dih-kwer-VAIN ten-oh-sine-oh-VIE-tis) is a painful condition affecting the tendons on the thumb side of the wrist. […] Although the exact cause of de Quervain tenosynovitis isn’t known, any activity that relies on repetitive hand or wrist movement such as working in the garden, playing golf or racket sports, or lifting a baby can make it worse. […] Chronic overuse, such as repeating a particular hand motion day after day, may irritate the covering around the tendons. If the covering becomes irritated, the tendons can thicken and swell. This thickening and swelling restrict the movement of the tendons through the small tunnel that connects them to the base of the thumb. […] Other causes of de Quervain tenosynovitis include: Inflammatory arthritis, such as rheumatoid arthritis. Direct injury to the wrist or tendon, which may cause scar tissue that restricts movement of the tendons. Fluid retention, such as from changes in hormones during pregnancy.

• #15 De Quervain’s Tenosynovitis | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.de-quervain’s-tenosynovitis.zd1018spec

  De Quervain’s (say „duh-kair-VANZ”) tenosynovitis, also called De Quervain’s, is a problem that makes the bottom of your thumb and the side of your wrist hurt. […] People can get de Quervain’s when they hurt or use the thumb or wrist too much. Common activities that need your wrist and thumb can cause the problem. Some activities that might cause de Quervain’s are: Wringing out wet clothes. Hammering. Skiing. Knitting. Lifting heavy objects such as a jug of milk, taking a frying pan off of the stove, or lifting a baby out of a crib. […] If you are pregnant or if you have diabetes or rheumatoid arthritis, you are more likely to get de Quervain’s. More women than men have de Quervain’s. You can get the disease at any age. Most people who have de Quervain’s are women between the ages of 30 and 50.

• #16 De Quervain’s Tendinitis: What Is It and Can It Be Treated?

  https://fortworthhandcenter.com/surgery/de-quervains-tendinitis-treatment/

  What Causes de Quervains Tendinitis? […] Though the exact cause of de Quervains tendinitis is not known, several risk factors include: […] Sports with repetitive movements Sports like tennis, racquetball, skiing, basketball, volleyball, weightlifting, etc., all involve repetitive bending, twisting, and gripping with the wrist and hand. […] Gender De Quervains tendinitis most often occurs in women (including pregnant women), especially those between the ages of 30 and 50. […] Parents with young children De Quervains tendinitis is also commonly called mommys thumb, parent thumb, or baby wrist as a result of the increased pressure involved in repetitively picking up and carrying a child with your arms in front of you and thumbs pointed toward the ceiling. […] Certain hobbies or jobs Certain hobbies, such as gardening, can cause increased pressure on the wrist. Jobs that might lead to the same condition include childcare, manual labor with tools and machines, computer-related work, hairdressing, construction, artists, painters, etc. […] Rheumatoid arthritis People who have already been diagnosed with rheumatoid arthritis may be more susceptible to de Quervains tendinitis. […] Injury Any direct injury to the wrist can lead to scar tissue that restricts movement in your tendons.

• #17

  https://www.hingehealth.com/resources/articles/de-quervains-tenosynovitis/

  De Quervains tenosynovitis, named after the surgeon Fritz de Quervain who first described this problem, refers to an irritation of the two main tendons the abductor pollicis longus (APL) and the extensor pollicis brevis (EPB) that help you straighten your thumb or move it away from your index finger. […] This relatively common problem happens when the tendons that run down the thumb side of the wrist become swollen and inflamed. […] People who have this problem often notice that the pain intensifies when they make a fist, grip an object, or even just rotate their wrist, says Dr. Reising. It can be more common in people who frequently pick up a baby or toddler, play racket sports, or engage their wrists in repetitive motion for another reason perhaps because of texting, doing martial arts, gardening, or styling hair.

• #18 De Quervain Tenosynovitis – StatPearls – NCBI Bookshelf

  https://www.ncbi.nlm.nih.gov/books/NBK442005/

  De Quervain tenosynovitis, named after Swiss surgeon Fritz de Quervain, is a condition that involves tendon entrapment affecting the first dorsal compartment of the wrist. […] While the exact cause of de Quervain tenosynovitis is unclear, it has been attributed to myxoid degeneration with fibrous tissue deposits and increased vascularity rather than acute inflammation of the synovial lining. This deposition results in the thickening of the tendon sheath, painfully entrapping the abductor pollicis longus and extensor pollicis brevis tendons. It is associated with repetitive wrist movements, specifically requiring thumb radial abduction, simultaneous extension, and radial wrist deviation. […] Some possible etiologies for the disease include acute injury to the wrist, increased frictional forces to the wrist by forceful movements of the wrist and the thumb, pathogenic causes, inflammatory ailments, and anatomical variations in the first dorsal compartment.

• #19 De Quervain Tenosynovitis: Practice Essentials, Anatomy, Etiology

  https://emedicine.medscape.com/article/1243387-overview

  The tendons of the abductor pollicis longus and the extensor pollicis brevis are tightly secured against the radial styloid by the overlying extensor retinaculum. Any thickening of the tendons from acute or repetitive trauma restrains gliding of the tendons through the sheath. Efforts at thumb motion, especially when combined with radial or ulnar deviation of the wrist, cause pain and perpetuate the inflammation and swelling.

• #20 De Quervain’s Tendinitis: What Is It and Can It Be Treated?

  https://fortworthhandcenter.com/surgery/de-quervains-tendinitis-treatment/

  What Causes de Quervains Tendinitis? […] Though the exact cause of de Quervains tendinitis is not known, several risk factors include: […] Sports with repetitive movements Sports like tennis, racquetball, skiing, basketball, volleyball, weightlifting, etc., all involve repetitive bending, twisting, and gripping with the wrist and hand. […] Gender De Quervains tendinitis most often occurs in women (including pregnant women), especially those between the ages of 30 and 50. […] Parents with young children De Quervains tendinitis is also commonly called mommys thumb, parent thumb, or baby wrist as a result of the increased pressure involved in repetitively picking up and carrying a child with your arms in front of you and thumbs pointed toward the ceiling. […] Certain hobbies or jobs Certain hobbies, such as gardening, can cause increased pressure on the wrist. Jobs that might lead to the same condition include childcare, manual labor with tools and machines, computer-related work, hairdressing, construction, artists, painters, etc. […] Rheumatoid arthritis People who have already been diagnosed with rheumatoid arthritis may be more susceptible to de Quervains tendinitis. […] Injury Any direct injury to the wrist can lead to scar tissue that restricts movement in your tendons.

• #21 De Quervain’s Syndrome | Florida Orthopaedic Institute

  https://www.floridaortho.com/specialties/hand-wrist/de-quervains-tenosynovitis/

  De Quervain’s tenosynovitis impacts the two tendons. […] Medical researchers have been unable to identify a specific cause of de Quervain’s tenosynovitis. Chronic overuse of the wrists could be a significant factor since tendons attach muscle to bone and are used in the smooth and fluid movement of the hand and wrist. […] People who consistently grip, grasp, or pinch are at higher risk by placing increased pressure on the wrist tendons. Additionally, traumatic wrist injuries or inflammation-inducing diseases, like arthritis, are thought to be potential triggering causes. […] Orthopedic specialists also think that the following risk factors might increase the chance of developing de Quervain’s tenosynovitis: Gender – Women are more likely to develop this condition; Age – De Quervain’s tenosynovitis typically strikes people between the ages of 30 and 50; Lifestyle – Persons with professions or hobbies necessitating frequent or awkward wrist movements may be at increased risk; Pregnancy – Expecting women are more likely to develop the problem. […] Parents of babies and young children are also considered a high-risk category since they often lift their children frequently and unintentionally use their thumbs for leverage and balance. These repeated motions place undue strain on thumb tendons that may lead to de Quervain’s tenosynovitis.

• #22

  https://www.gleneagles.com.sg/conditions-diseases/de-quervains-tenosynovitis/symptoms-causes

  De Quervains tenosynovitis is usually caused by chronic overuse of the wrist from daily repetitive movements. […] Its a common affliction among mothers from activities such as cradling an infant while nursing, lifting a child into a high chair or car seat, or carrying heavy bags of groceries.

• #23 What is De Quervain’s Tenosynovitis and How does it happen? | Merivale Hand Clinic

  https://www.merivalehandclinic.co.nz/resource-hub/what-is-de-quervains-tenosynovitis-and-how-does-it-happen/

  De Quervains tenosynovitis is a condition that affects two tendons that run from the back of the thumb down the side of the wrist. De Quervains tenosynovitis is the name given to the condition that occurs when these tendons are swollen and irritated. […] May be caused by repetitive movement of the thumb and wrist e.g., repetitive use of a screwdriver. […] Is the second most common hand and wrist problem occurring during pregnancy and the postpartum period. Fluid retention during the third trimester of pregnancy and repetitive picking up of the baby in particular positions that are needed for nursing and care of the child predispose new mothers to tenosynovitis. […] Diabetes and auto-immune disorders such as rheumatoid arthritis, lupus, and hypothyroidism are associated with an increased risk of diagnosis.

• #24 What is De Quervain’s Tenosynovitis and How does it happen? | Merivale Hand Clinic

  https://www.merivalehandclinic.co.nz/resource-hub/what-is-de-quervains-tenosynovitis-and-how-does-it-happen/

  De Quervains tenosynovitis is a condition that affects two tendons that run from the back of the thumb down the side of the wrist. De Quervains tenosynovitis is the name given to the condition that occurs when these tendons are swollen and irritated. […] May be caused by repetitive movement of the thumb and wrist e.g., repetitive use of a screwdriver. […] Is the second most common hand and wrist problem occurring during pregnancy and the postpartum period. Fluid retention during the third trimester of pregnancy and repetitive picking up of the baby in particular positions that are needed for nursing and care of the child predispose new mothers to tenosynovitis. […] Diabetes and auto-immune disorders such as rheumatoid arthritis, lupus, and hypothyroidism are associated with an increased risk of diagnosis.

• #25 de Quervain’s Tenosynovitis: Signs & Symptoms | The Hand Society

  https://www.assh.org/handcare/condition/dequervains-tenosynovitis

  Patients with de Quervains Tenosynovitis have painful tendons on the thumb side of the wrist. […] In de Quervains Tenosynovitis, the tunnel (the first extensor compartment) where the tendons run can narrow, or the tendons can take up extra space in the tunnel. This can be due to a thickening of the soft tissues that make up the tunnel or an increase in the amount of soft tissue within the tunnel. […] Doctors are not sure what causes de Quervains Tenosynovitis, but changes in the use of the hand may be a cause. Repetitive movements, changes in hormones, and swelling are likely factors. When new mothers develop this condition, it typically appears 4 to 6 weeks after delivery.

• #26 De Quervain tenosynovitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/de-quervain-tenosynovitis/symptoms-causes/syc-20371332

  De Quervain tenosynovitis (dih-kwer-VAIN ten-oh-sine-oh-VIE-tis) is a painful condition affecting the tendons on the thumb side of the wrist. […] Although the exact cause of de Quervain tenosynovitis isn’t known, any activity that relies on repetitive hand or wrist movement such as working in the garden, playing golf or racket sports, or lifting a baby can make it worse. […] Chronic overuse, such as repeating a particular hand motion day after day, may irritate the covering around the tendons. If the covering becomes irritated, the tendons can thicken and swell. This thickening and swelling restrict the movement of the tendons through the small tunnel that connects them to the base of the thumb. […] Other causes of de Quervain tenosynovitis include: Inflammatory arthritis, such as rheumatoid arthritis. Direct injury to the wrist or tendon, which may cause scar tissue that restricts movement of the tendons. Fluid retention, such as from changes in hormones during pregnancy.

• #27

  https://www.nuh.com.sg/health-resources/diseases-and-conditions/de-quervain-tenosynovitis

  De Quervain tenosynovitis is characterised by pain localised to the wrist joint, specifically near the base of the thumb. The tendons responsible for extending and abducting the thumb experience constriction in a tight tunnel, leading to progressive inflammation caused by friction and repetitive tendon gliding. […] The exact cause of de Quervain tenosynovitis has not been established. However, inflammation of the tendons has been associated with repetitive trauma or overuse of the thumb and wrist in daily activities, such as: […] Sustaining direct injury to the wrist or tendon, leading to tissue scarring.

• #28 De Quervain’s Tenosynovitis – Causes, Symptoms & Treatment

  https://www.melbournehandtherapy.com.au/conditions-treated/dequervains-tenosynovitis/

  De Quervains tenosynovitis/disease (DQV), is an overuse condition that results in pain on the radial or thumb side of the wrist. […] DQV is a common condition that is generally linked to overuse and work related, repetitive movements. There are many activities in our daily lives that may result in the development of DQV. […] Increased use of mobile phones, ipads, gaming consoles. […] Pregnancy increased fluid can result in more pressure at the wrist. […] New parents/grandparents repetitive lifting with thumbs extended, patting, prolonged holding during feeds with wrist in end range flexion. […] Commencement of high intensity and jarring workouts kettlebells, burpees, push up challenges, etc. […] Manual workers or DIY enthusiasts increased repetitive tasks, eg: painting, moving bricks, etc. This can include a one off day of intense work. […] Underlying chronic inflammatory conditions, eg: osteo or rheumatoid arthritis. […] Direct trauma to the area. […] Scar tissue from wrist fractures, leading to reduced glide of the EPB/APL tendons.

• #29 de Quervain’s Tenosynovitis: Causes & Treatment – familydoctor.org

  https://familydoctor.org/condition/de-quervains-tenosynovitis/

  De Quervain’s tenosynovitis is a painful condition that affects the tendons in your wrist. It occurs when the 2 tendons around the base of your thumb become swollen. The swelling causes the sheaths (casings) covering the tendons to become inflamed. This puts pressure on nearby nerves, causing pain and numbness. […] The most common cause of de Quervain’s tenosynovitis is chronic overuse of the wrist. Repetitive movements day after day cause irritation and pain. One common movement that causes it is lifting a child into a car seat. Another is lifting heavy grocery bags by the handles. Other causes could include a direct injury to the wrist or inflammatory arthritis. […] You are more likely to develop de Quervain’s tenosynovitis if: You are a woman; You are 40 years of age or older; Your hobby or job involves repetitive hand and wrist motions. This is a very common cause; You have injured your wrist. Scar tissue can restrict the movement of your tendons; You are pregnant. Hormonal changes during pregnancy can cause it; You have arthritis.

• #30 De Quervain Tenosynovitis: Symptoms, Causes, and Treatment

  https://www.healthline.com/health/de-quervain-tenosynovitis

  De Quervain tenosynovitis develops due to the thickening and degeneration of the protective tendon sheath around the tendons of your thumb. This thickening can trap your tendons and lead to pain and swelling. […] Its often caused by repetitive thumb or wrist motions, specifically motions requiring radial abduction. Radial abduction is the movement of your thumb away from your index finger. Less commonly, a sudden traumatic injury may lead to de Quervain tenosynovitis. […] De Quervain tenosynovitis is often triggered by repetitive wrist activities like playing tennis or breastfeeding a newborn. […] If left untreated, de Quervain tenosynovitis might cause progressive pain and discomfort.

• #31 de Quervain’s Tenosynovitis: Causes & Treatment – familydoctor.org

  https://familydoctor.org/condition/de-quervains-tenosynovitis/

  De Quervain’s tenosynovitis is a painful condition that affects the tendons in your wrist. It occurs when the 2 tendons around the base of your thumb become swollen. The swelling causes the sheaths (casings) covering the tendons to become inflamed. This puts pressure on nearby nerves, causing pain and numbness. […] The most common cause of de Quervain’s tenosynovitis is chronic overuse of the wrist. Repetitive movements day after day cause irritation and pain. One common movement that causes it is lifting a child into a car seat. Another is lifting heavy grocery bags by the handles. Other causes could include a direct injury to the wrist or inflammatory arthritis. […] You are more likely to develop de Quervain’s tenosynovitis if: You are a woman; You are 40 years of age or older; Your hobby or job involves repetitive hand and wrist motions. This is a very common cause; You have injured your wrist. Scar tissue can restrict the movement of your tendons; You are pregnant. Hormonal changes during pregnancy can cause it; You have arthritis.

• #32 De Quervain tenosynovitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/de-quervain-tenosynovitis/symptoms-causes/syc-20371332

  De Quervain tenosynovitis (dih-kwer-VAIN ten-oh-sine-oh-VIE-tis) is a painful condition affecting the tendons on the thumb side of the wrist. […] Although the exact cause of de Quervain tenosynovitis isn’t known, any activity that relies on repetitive hand or wrist movement such as working in the garden, playing golf or racket sports, or lifting a baby can make it worse. […] Chronic overuse, such as repeating a particular hand motion day after day, may irritate the covering around the tendons. If the covering becomes irritated, the tendons can thicken and swell. This thickening and swelling restrict the movement of the tendons through the small tunnel that connects them to the base of the thumb. […] Other causes of de Quervain tenosynovitis include: Inflammatory arthritis, such as rheumatoid arthritis. Direct injury to the wrist or tendon, which may cause scar tissue that restricts movement of the tendons. Fluid retention, such as from changes in hormones during pregnancy.

• #33 De Quervain’s Tenosynovitis – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/de-quervains-tendinosis/

  De Quervain’s tenosynovitis is swelling of the tendons that run along the thumb side of the wrist and attach to the base of the thumb. This occurs when the tendons are constricted by the sheath that they run through to get from the wrist to the hand. […] De Quervain’s tenosynovitis is common and may be caused by overuse of the thumb and wrist. […] It also is associated with pregnancy and breastfeeding. […] People with rheumatoid arthritis may be more susceptible to De Quervain’s tenosynovitis. […] It is most common in people in their 40s and 50s and affects more women than men.

• #34 De Quervain’s Tenosynovitis: Symptoms & Causes | NewYork-Presbyterian

  https://www.nyp.org/orthopedics/columbia-orthopedics/de-quervains-tenosynovitis

  De Quervain’s tenosynovitis causes swelling of the tendons around the base of your thumb, resulting in tenderness and pain along the inside of your wrist. […] In people with de Quervain’s tenosynovitis (also known as de Quervain’s syndrome, de Quervain’s disease, or de Quervain’s tendinosis), the tendons become swollen or the sheath thickens. This puts pressure and friction on the tendons and inhibits their ability to slide smoothly through the sheath, causing inflammation and pain. […] De Quervain’s tenosynovitis most often happens from overuse, when you do too much of a certain type of movement (repetitive stress injury). It may also result from a direct injury to the thumb or rheumatoid arthritis.

• #35 What is De Quervain’s Tenosynovitis and How does it happen? | Merivale Hand Clinic

  https://www.merivalehandclinic.co.nz/resource-hub/what-is-de-quervains-tenosynovitis-and-how-does-it-happen/

  De Quervains tenosynovitis is a condition that affects two tendons that run from the back of the thumb down the side of the wrist. De Quervains tenosynovitis is the name given to the condition that occurs when these tendons are swollen and irritated. […] May be caused by repetitive movement of the thumb and wrist e.g., repetitive use of a screwdriver. […] Is the second most common hand and wrist problem occurring during pregnancy and the postpartum period. Fluid retention during the third trimester of pregnancy and repetitive picking up of the baby in particular positions that are needed for nursing and care of the child predispose new mothers to tenosynovitis. […] Diabetes and auto-immune disorders such as rheumatoid arthritis, lupus, and hypothyroidism are associated with an increased risk of diagnosis.

• #36 De Quervain’s Tenosynovitis | Orthopedic Medical Center

  https://www.orthomedctr.com/de-quervains-tenosynovitis.php

  De Quervain’s tenosynovitis is an inflammation of the two tendons that run from the back of thumb and down the side of the wrist. The causes of De Quervain’s tenosynovitis are unknown, but it has been linked to wrist injury, overuse/repetitive motion, pregnancy and inflammatory arthritis. […] It is much more common in women than in men, and in people who have diabetes or arthritis.

• #37 De Quervain tenosynovitis | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/de-quervain-tenosynovitis?lang=us

  De Quervain tenosynovitis, also known as washerwoman’s sprain/strain, is a painful stenosing tenosynovitis involving the first extensor (dorsal) tendon compartment of the wrist (typically at the radial styloid). This compartment contains the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons. […] De Quervain tenosynovitis is the second most common entrapment tendinopathy in the hand following trigger finger. It usually occurs in middle-aged individuals and is around 3x more common in women (~80% of cases). Most cases are associated with overuse, however, local trauma can also precipitate the condition. […] Thickening of the retinaculum and tendons from acute or repetitive trauma restrains normal gliding within the sheath. This causes inflammation and further edematous thickening of the tendon exacerbating the local stenosing effect. […] In ~10% of patients, there is an intertendinous septum between APL and EPB. The absence of a septum is associated with very high rates (almost 100%) of complete symptom resolution with conservative management. Presence of a septum increases the likelihood that surgical management will be required.

• #38 De Quervain syndrome – Wikipedia

  https://en.wikipedia.org/wiki/De_Quervain_syndrome

  De Quervain syndrome occurs when two tendons that control movement of the thumb become constricted by their tendon sheath in the wrist. This results in pain and tenderness on the thumb side of the wrist. The cause of de Quervain syndrome is not established. Critics of this association note of the human mind’s tendency to misinterpret activities that are painful as activities that make the problem worse. Evidence regarding a possible relation with activity and occupation is debated. A systematic review of potential risk factors did not find any evidence of a causal relationship with activity or occupation. One study found that personal and work-related factors were associated with the diagnosis of de Quervain syndrome in a working population; wrist bending and movements associated with the twisting or driving of screws were the most significant of the work-related factors. Proponents of the view that de Quervain syndrome is a repetitive strain injury consider postures where the thumb is held in abduction and extension to be predisposing factors. The incidence of diagnosis of the condition is higher in women than in men. The syndrome commonly occurs during and, even more so, after pregnancy. Contributory factors may include hormonal changes, fluid retention and again, more debatably increased housework and lifting.

• #39 De Quervain’s Tenosynovitis – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/de-quervains-tendinosis/

  De Quervain’s tenosynovitis is swelling of the tendons that run along the thumb side of the wrist and attach to the base of the thumb. This occurs when the tendons are constricted by the sheath that they run through to get from the wrist to the hand. […] De Quervain’s tenosynovitis is common and may be caused by overuse of the thumb and wrist. […] It also is associated with pregnancy and breastfeeding. […] People with rheumatoid arthritis may be more susceptible to De Quervain’s tenosynovitis. […] It is most common in people in their 40s and 50s and affects more women than men.

• #40 De Quervain tenosynovitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/de-quervain-tenosynovitis/symptoms-causes/syc-20371332

  De Quervain tenosynovitis (dih-kwer-VAIN ten-oh-sine-oh-VIE-tis) is a painful condition affecting the tendons on the thumb side of the wrist. […] Although the exact cause of de Quervain tenosynovitis isn’t known, any activity that relies on repetitive hand or wrist movement such as working in the garden, playing golf or racket sports, or lifting a baby can make it worse. […] Chronic overuse, such as repeating a particular hand motion day after day, may irritate the covering around the tendons. If the covering becomes irritated, the tendons can thicken and swell. This thickening and swelling restrict the movement of the tendons through the small tunnel that connects them to the base of the thumb. […] Other causes of de Quervain tenosynovitis include: Inflammatory arthritis, such as rheumatoid arthritis. Direct injury to the wrist or tendon, which may cause scar tissue that restricts movement of the tendons. Fluid retention, such as from changes in hormones during pregnancy.

• #41 Symptoms and Risk Factors for De Quervain’s Tenosynovitis

  https://www.sports-health.com/sports-injuries/hand-and-wrist-injuries/symptoms-and-risk-factors-de-quervains-tenosynovitis

  De Quervains tenosynovitis is a condition in which inflammation in tendons in the thumb cause pain in the thumb and hand. […] While De Quervains tenosynovitis can affect just about any adult, there are certain factors that can raise individuals risk for the condition: Being female, Being age 40 or older, Performing repetitive tasks that involve hand or wrist movement, often as part of a job, sport, or hobby, Caring for a child, since repeatedly lifting a baby puts strain on the thumbs (the condition is sometimes known as mommy thumb for this reason), Previous wrist injury scar tissue can impede tendon movement, Having a type of inflammatory arthritis such as rheumatoid arthritis, Being pregnant fluctuating hormone levels can make inflammation more likely. […] With the exception of pregnant women whose cases of De Quervains tenosynovitis often resolve when they are no longer pregnant or breastfeeding De Quervains tenosynovitis will not resolve on its own without treatment.

• #42 What is De Quervain’s Tenosynovitis and How does it happen? | Merivale Hand Clinic

  https://www.merivalehandclinic.co.nz/resource-hub/what-is-de-quervains-tenosynovitis-and-how-does-it-happen/

  De Quervains tenosynovitis is a condition that affects two tendons that run from the back of the thumb down the side of the wrist. De Quervains tenosynovitis is the name given to the condition that occurs when these tendons are swollen and irritated. […] May be caused by repetitive movement of the thumb and wrist e.g., repetitive use of a screwdriver. […] Is the second most common hand and wrist problem occurring during pregnancy and the postpartum period. Fluid retention during the third trimester of pregnancy and repetitive picking up of the baby in particular positions that are needed for nursing and care of the child predispose new mothers to tenosynovitis. […] Diabetes and auto-immune disorders such as rheumatoid arthritis, lupus, and hypothyroidism are associated with an increased risk of diagnosis.

• #43 De Quervain’s tenosynovitis | Ohio State Medical Center

  https://wexnermedical.osu.edu/orthopedics/hand-and-upper-extremity/de-quervains-tenosynovitis

  De Quervains tenosynovitis, a type of wrist tendonitis, is an inflammation of the wrist tendons at the base of the thumb. […] This condition often happens because of new, repeated activities using the hand. New mothers are often at risk for this tendonitis because of changes in hormones during pregnancy and cradling and nursing the new baby. […] People who have had a broken wrist or who have inflammatory arthritis may also be at risk.

• #44 Symptoms and Risk Factors for De Quervain’s Tenosynovitis

  https://www.sports-health.com/sports-injuries/hand-and-wrist-injuries/symptoms-and-risk-factors-de-quervains-tenosynovitis

  De Quervains tenosynovitis is a condition in which inflammation in tendons in the thumb cause pain in the thumb and hand. […] While De Quervains tenosynovitis can affect just about any adult, there are certain factors that can raise individuals risk for the condition: Being female, Being age 40 or older, Performing repetitive tasks that involve hand or wrist movement, often as part of a job, sport, or hobby, Caring for a child, since repeatedly lifting a baby puts strain on the thumbs (the condition is sometimes known as mommy thumb for this reason), Previous wrist injury scar tissue can impede tendon movement, Having a type of inflammatory arthritis such as rheumatoid arthritis, Being pregnant fluctuating hormone levels can make inflammation more likely. […] With the exception of pregnant women whose cases of De Quervains tenosynovitis often resolve when they are no longer pregnant or breastfeeding De Quervains tenosynovitis will not resolve on its own without treatment.

• #45 de Quervain’s Tenosynovitis: Causes & Treatment – familydoctor.org

  https://familydoctor.org/condition/de-quervains-tenosynovitis/

  De Quervain’s tenosynovitis is a painful condition that affects the tendons in your wrist. It occurs when the 2 tendons around the base of your thumb become swollen. The swelling causes the sheaths (casings) covering the tendons to become inflamed. This puts pressure on nearby nerves, causing pain and numbness. […] The most common cause of de Quervain’s tenosynovitis is chronic overuse of the wrist. Repetitive movements day after day cause irritation and pain. One common movement that causes it is lifting a child into a car seat. Another is lifting heavy grocery bags by the handles. Other causes could include a direct injury to the wrist or inflammatory arthritis. […] You are more likely to develop de Quervain’s tenosynovitis if: You are a woman; You are 40 years of age or older; Your hobby or job involves repetitive hand and wrist motions. This is a very common cause; You have injured your wrist. Scar tissue can restrict the movement of your tendons; You are pregnant. Hormonal changes during pregnancy can cause it; You have arthritis.

• #46

  https://myhealth.alberta.ca/Health/pages/conditions.aspx?hwid=zd1018spec

  De Quervain’s (say „duh-kair-VANZ”) tenosynovitis, also called De Quervain’s, is a problem that makes the bottom of your thumb and the side of your wrist hurt. […] People can get de Quervain’s when they hurt or use the thumb or wrist too much. Common activities that need your wrist and thumb can cause the problem. Some activities that might cause de Quervain’s are: […] If you are pregnant or if you have diabetes or rheumatoid arthritis, you are more likely to get de Quervain’s. […] Most people who have de Quervain’s are women between the ages of 30 and 50.

• #47 De Quervain tenosynovitis | Radiology Reference Article | Radiopaedia.org

  https://radiopaedia.org/articles/de-quervain-tenosynovitis?lang=us

  De Quervain tenosynovitis, also known as washerwoman’s sprain/strain, is a painful stenosing tenosynovitis involving the first extensor (dorsal) tendon compartment of the wrist (typically at the radial styloid). This compartment contains the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons. […] De Quervain tenosynovitis is the second most common entrapment tendinopathy in the hand following trigger finger. It usually occurs in middle-aged individuals and is around 3x more common in women (~80% of cases). Most cases are associated with overuse, however, local trauma can also precipitate the condition. […] Thickening of the retinaculum and tendons from acute or repetitive trauma restrains normal gliding within the sheath. This causes inflammation and further edematous thickening of the tendon exacerbating the local stenosing effect. […] In ~10% of patients, there is an intertendinous septum between APL and EPB. The absence of a septum is associated with very high rates (almost 100%) of complete symptom resolution with conservative management. Presence of a septum increases the likelihood that surgical management will be required.

• #48 De Quervain’s Tendinosis: Symptoms, Causes, Diagnosis & Treatment

  https://www.clevelandclinicabudhabi.ae/en/health-hub/health-resource/diseases-and-conditions/de-quervains-tendinosis

  De Quervain’s tendinosis is a painful swelling (inflammation) of specific tendons of the thumb. […] Overuse, a direct blow to the thumb, repetitive grasping and certain inflammatory conditions (such as rheumatoid arthritis), can all trigger the tendinosis. […] Often, its cause is unknown. De Quervain’s affects women eight to 10 times more often than men.

• #49 De Quervain’s Tenosynovitis | Kaiser Permanente

  https://healthy.kaiserpermanente.org/health-wellness/health-encyclopedia/he.de-quervain’s-tenosynovitis.zd1018spec

  De Quervain’s (say „duh-kair-VANZ”) tenosynovitis, also called De Quervain’s, is a problem that makes the bottom of your thumb and the side of your wrist hurt. […] People can get de Quervain’s when they hurt or use the thumb or wrist too much. Common activities that need your wrist and thumb can cause the problem. Some activities that might cause de Quervain’s are: Wringing out wet clothes. Hammering. Skiing. Knitting. Lifting heavy objects such as a jug of milk, taking a frying pan off of the stove, or lifting a baby out of a crib. […] If you are pregnant or if you have diabetes or rheumatoid arthritis, you are more likely to get de Quervain’s. More women than men have de Quervain’s. You can get the disease at any age. Most people who have de Quervain’s are women between the ages of 30 and 50.

• #50 De Quervain’s Tenosynovitis – OrthoInfo – AAOS

  https://orthoinfo.aaos.org/en/diseases–conditions/de-quervains-tendinosis/

  De Quervain’s tenosynovitis is swelling of the tendons that run along the thumb side of the wrist and attach to the base of the thumb. This occurs when the tendons are constricted by the sheath that they run through to get from the wrist to the hand. […] De Quervain’s tenosynovitis is common and may be caused by overuse of the thumb and wrist. […] It also is associated with pregnancy and breastfeeding. […] People with rheumatoid arthritis may be more susceptible to De Quervain’s tenosynovitis. […] It is most common in people in their 40s and 50s and affects more women than men.

• #51 De Quervain’s Tenosynovitis Causes, Symptoms, Treatment, Medications, Prevention

  https://www.medicinenet.com/de_quervains_tenosynovitis/article.htm

  De Quervain’s tenosynovitis can be brought on by simple strain injury to the extensor pollicis longus and abductor pollicis tendons (tendinitis). Often this form of tendinitis is a result of repetitive motion injury. Typical causes of de Quervain’s tenosynovitis include stresses such as lifting young children into car seats, lifting heavy grocery bags by the loops, and lifting gardening pots up and into place. […] Risk factors for de Quervain’s tenosynovitis include the following: Being female, Age over 40, African ethnicity/descent, Pregnancy. […] De Quervain’s tenosynovitis can be prevented by avoiding activities that stress the wrist and avoiding repetitive motion injuries.

• #52 De Quervain Tenosynovitis: Practice Essentials, Anatomy, Etiology

  https://emedicine.medscape.com/article/1243387-overview

  The tendons of the abductor pollicis longus and the extensor pollicis brevis are tightly secured against the radial styloid by the overlying extensor retinaculum. Any thickening of the tendons from acute or repetitive trauma restrains gliding of the tendons through the sheath. Efforts at thumb motion, especially when combined with radial or ulnar deviation of the wrist, cause pain and perpetuate the inflammation and swelling.

• #53 What are the causes of De Quervain’s Syndrome?

  https://learnmuscles.com/blog/2025/01/02/causes-de-quervains-syndrome/

  Stenosing tenosynovitis of the tendon sheath of the APL and EPB is common enough to merit its own name because of its proximity to the styloid process of the radius. When these muscles contract to move the thumb, their tendon sheath rubs against the styloid process of the radius and becomes irritated and inflamed. The inflammatory process draws in fibroblasts that lay down collagen fibrin thread adhesions within the sheath. These adhesions impair movement of the tendon within the sheath and therefore impair movement of the thumb, and cause pain when movement is attempted. […] Therefore, De Quervains syndrome is caused by overuse of the thumb, specifically the APL and EPB. This overuse can be concentric contraction to abduct and/or extend the thumb. Or it can be eccentric contraction to slow down adduction and/or flexion of the thumb, or isometric contraction to stabilize the thumb. Continued stretching of these muscles by adduction and flexion will also stretch and tauten the tendon sheath as it rubs against the radial styloid.

• #54 De Quervain tenosynovitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/de-quervain-tenosynovitis/symptoms-causes/syc-20371332

  De Quervain tenosynovitis (dih-kwer-VAIN ten-oh-sine-oh-VIE-tis) is a painful condition affecting the tendons on the thumb side of the wrist. […] Although the exact cause of de Quervain tenosynovitis isn’t known, any activity that relies on repetitive hand or wrist movement such as working in the garden, playing golf or racket sports, or lifting a baby can make it worse. […] Chronic overuse, such as repeating a particular hand motion day after day, may irritate the covering around the tendons. If the covering becomes irritated, the tendons can thicken and swell. This thickening and swelling restrict the movement of the tendons through the small tunnel that connects them to the base of the thumb. […] Other causes of de Quervain tenosynovitis include: Inflammatory arthritis, such as rheumatoid arthritis. Direct injury to the wrist or tendon, which may cause scar tissue that restricts movement of the tendons. Fluid retention, such as from changes in hormones during pregnancy.

• #55 De Quervain tenosynovitis // Middlesex Health

  https://middlesexhealth.org/learning-center/diseases-and-conditions/de-quervain-tenosynovitis

  Although the exact cause of de Quervain tenosynovitis isn’t known, any activity that relies on repetitive hand or wrist movement such as working in the garden, playing golf or racket sports, or lifting a baby can make it worse. […] Chronic overuse, such as repeating a particular hand motion day after day, may irritate the covering around the tendons. If the covering becomes irritated, the tendons can thicken and swell. This thickening and swelling restrict the movement of the tendons through the small tunnel that connects them to the base of the thumb. […] Other causes of de Quervain tenosynovitis include: Inflammatory arthritis, such as rheumatoid arthritis. Direct injury to the wrist or tendon, which may cause scar tissue that restricts movement of the tendons. Fluid retention, such as from changes in hormones during pregnancy.

• #56 What are the causes of De Quervain’s Syndrome?

  https://learnmuscles.com/blog/2025/01/02/causes-de-quervains-syndrome/

  Stenosing tenosynovitis of the tendon sheath of the APL and EPB is common enough to merit its own name because of its proximity to the styloid process of the radius. When these muscles contract to move the thumb, their tendon sheath rubs against the styloid process of the radius and becomes irritated and inflamed. The inflammatory process draws in fibroblasts that lay down collagen fibrin thread adhesions within the sheath. These adhesions impair movement of the tendon within the sheath and therefore impair movement of the thumb, and cause pain when movement is attempted. […] Therefore, De Quervains syndrome is caused by overuse of the thumb, specifically the APL and EPB. This overuse can be concentric contraction to abduct and/or extend the thumb. Or it can be eccentric contraction to slow down adduction and/or flexion of the thumb, or isometric contraction to stabilize the thumb. Continued stretching of these muscles by adduction and flexion will also stretch and tauten the tendon sheath as it rubs against the radial styloid.

• #57 De Quervain’s Tenosynovitis Causes, Symptoms, Treatment, Medications, Prevention

  https://www.medicinenet.com/de_quervains_tenosynovitis/article.htm

  De Quervain’s tenosynovitis can be brought on by simple strain injury to the extensor pollicis longus and abductor pollicis tendons (tendinitis). Often this form of tendinitis is a result of repetitive motion injury. Typical causes of de Quervain’s tenosynovitis include stresses such as lifting young children into car seats, lifting heavy grocery bags by the loops, and lifting gardening pots up and into place. […] Risk factors for de Quervain’s tenosynovitis include the following: Being female, Age over 40, African ethnicity/descent, Pregnancy. […] De Quervain’s tenosynovitis can be prevented by avoiding activities that stress the wrist and avoiding repetitive motion injuries.

• #58 What are the causes of De Quervain’s Syndrome?

  https://learnmuscles.com/blog/2025/01/02/causes-de-quervains-syndrome/

  Once De Quervains syndrome is present, another cause that perpetuates the condition is sleeping with the hand/thumb in a position that stretches and aggravates the tendons/sheath. For this reason, wearing a brace at night that maintains the hand in neutral posture is often recommended. And, in addition to repeated postural/activity overuse of the APL and EPB, a direct physical macrotrauma to the tendons/sheath is another factor that can cause/perpetuate the condition.

• #59 De Quervain’s Disease: A Discourse on Etiology, Diagnosis, and Treatment

  https://pmc.ncbi.nlm.nih.gov/articles/PMC10208847/

  De Quervains tenosynovitis, also known as De Quervains disease (DQD), is a painful condition that affects the tendons on the lateral side of the wrist. It is caused by inflammation of the tendons that control the movement of the thumb, specifically the abductor pollicis longus (APL) and extensor pollicis brevis (EPB). […] The preliminary literature suggests that DQD results from myxoid degeneration rather than an underlying inflammatory process. On the contrary, present-day investigation emphasizes the inflammatory markers that may cause a predisposition to this condition. […] The exact etiology of DQD is a subject of investigation; many prevailing theories have arisen since De Quervain first postulated its origin in his preliminary paper. […] Several explanations for the underlying cause of DQD have been proposed since its discovery.

• #60 De Quervain tenosynovitis – Symptoms and causes – Mayo Clinic

  https://www.mayoclinic.org/diseases-conditions/de-quervain-tenosynovitis/symptoms-causes/syc-20371332

  De Quervain tenosynovitis (dih-kwer-VAIN ten-oh-sine-oh-VIE-tis) is a painful condition affecting the tendons on the thumb side of the wrist. […] Although the exact cause of de Quervain tenosynovitis isn’t known, any activity that relies on repetitive hand or wrist movement such as working in the garden, playing golf or racket sports, or lifting a baby can make it worse. […] Chronic overuse, such as repeating a particular hand motion day after day, may irritate the covering around the tendons. If the covering becomes irritated, the tendons can thicken and swell. This thickening and swelling restrict the movement of the tendons through the small tunnel that connects them to the base of the thumb. […] Other causes of de Quervain tenosynovitis include: Inflammatory arthritis, such as rheumatoid arthritis. Direct injury to the wrist or tendon, which may cause scar tissue that restricts movement of the tendons. Fluid retention, such as from changes in hormones during pregnancy.

• #61 De Quervain tenosynovitis // Middlesex Health

  https://middlesexhealth.org/learning-center/diseases-and-conditions/de-quervain-tenosynovitis

  Although the exact cause of de Quervain tenosynovitis isn’t known, any activity that relies on repetitive hand or wrist movement such as working in the garden, playing golf or racket sports, or lifting a baby can make it worse. […] Chronic overuse, such as repeating a particular hand motion day after day, may irritate the covering around the tendons. If the covering becomes irritated, the tendons can thicken and swell. This thickening and swelling restrict the movement of the tendons through the small tunnel that connects them to the base of the thumb. […] Other causes of de Quervain tenosynovitis include: Inflammatory arthritis, such as rheumatoid arthritis. Direct injury to the wrist or tendon, which may cause scar tissue that restricts movement of the tendons. Fluid retention, such as from changes in hormones during pregnancy.

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